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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3jqrFADFerredoxin--NADP reductase, apicoplast

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3jqrFADFerredoxin--NADP reductase, apicoplast/1.000
1bx0FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.600
1fnbFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.599
3zc3FADFerredoxin--NADP reductase1.18.1.20.598
1bx1FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.593
1gawFADFerredoxin/0.590
1fndFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.589
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.587
1gjrFADFerredoxin--NADP reductase1.18.1.20.576
1h42FADFerredoxin--NADP reductase1.18.1.20.570
1fncFDAFerredoxin--NADP reductase, chloroplastic1.18.1.20.568
2ok8FADFerredoxin--NADP reductase, apicoplast/0.567
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.564
3vo2FADFerredoxin--NADP reductase/0.562
1gaqFADFerredoxin/0.555
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.555
1w35FADFerredoxin--NADP reductase1.18.1.20.552
3w5uFADFerredoxin/0.551
1queFADFerredoxin--NADP reductase1.18.1.20.544
1sm4FADFerredoxin--NADP reductase/0.543
2rc6FADFerredoxin--NADP reductase/0.533
1h85FADFerredoxin--NADP reductase1.18.1.20.531
1gr1FADFerredoxin--NADP reductase1.18.1.20.530
4c43FADFerredoxin--NADP reductase1.18.1.20.527
1qh0FADFerredoxin--NADP reductase1.18.1.20.526
1ogiFADFerredoxin--NADP reductase1.18.1.20.525
1ogjFADFerredoxin--NADP reductase1.18.1.20.523
2b5oFADFerredoxin--NADP reductase1.18.1.20.520
1e62FADFerredoxin--NADP reductase1.18.1.20.519
3qfcFADNADPH--cytochrome P450 reductase/0.516
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.514
4bprFADFerredoxin--NADP reductase1.18.1.20.514
1w87FADFerredoxin--NADP reductase1.18.1.20.510
1e64FADFerredoxin--NADP reductase1.18.1.20.509
1qgyFADFerredoxin--NADP reductase1.18.1.20.507
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.505
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.505
3fpkFADFerredoxin-NADP reductase/0.503
1e63FADFerredoxin--NADP reductase1.18.1.20.500
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.500
1go2FADFerredoxin--NADP reductase1.18.1.20.499
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.499
2ejzSAHDiphthine synthase/0.498
3zbtFADFerredoxin--NADP reductase1.18.1.20.498
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.496
1qgzFADFerredoxin--NADP reductase1.18.1.20.495
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.493
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.492
1x1bSAHC-20 methyltransferase/0.492
2watCOAFatty acid synthase subunit alpha2.3.1.860.492
1c7oPPGHemolysin/0.489
4e32DWNMethyltransferase/0.489
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.488
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.487
4jtqNAPAldo-keto reductase family 1 member C2/0.487
1ja1FADNADPH--cytochrome P450 reductase/0.485
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.485
2futH1SHeparin and heparin-sulfate lyase/0.484
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.483
1x1cSAHC-20 methyltransferase/0.482
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.482
3c1oNAPEugenol synthase/0.482
3f6sFMNFlavodoxin/0.482
3ska053Genome polyprotein2.7.7.480.482
4b4w9L9Bifunctional protein FolD/0.482
1cqp803Integrin alpha-L/0.481
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.481
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.481
3qftFADNADPH--cytochrome P450 reductase/0.481
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.480
2ij7TPFMycocyclosin synthase1.14.21.90.480
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.480
2c20NADUDP-glucose 4-epimerase/0.479
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.478
3keqNADRedox-sensing transcriptional repressor Rex/0.478
4c77N01Phenylacetone monooxygenase1.14.13.920.478
4d03NAPPhenylacetone monooxygenase1.14.13.920.478
1r5hAO2Methionine aminopeptidase 2/0.477
1xddAAYIntegrin alpha-L/0.476
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.476
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.475
3f90FMNFlavodoxin/0.475
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.475
1k7fIAVTryptophan synthase alpha chain/0.474
1yw7A41Methionine aminopeptidase 2/0.474
2r8pT6FTransketolase 1/0.474
3fr5I4AFatty acid-binding protein, adipocyte/0.474
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.474
1w6jR71Lanosterol synthase5.4.99.70.473
3qe2FADNADPH--cytochrome P450 reductase/0.473
3rsv3RSBeta-secretase 13.4.23.460.473
2j83BATUlilysin3.4.240.472
3bgxMEFThymidylate synthase/0.472
3klbFMNUncharacterized protein/0.472
4dyb0MHNucleoprotein/0.472
5a4vQUEGlutathione S-transferase F22.5.1.180.472
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.471
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
4yaoFADNADPH--cytochrome P450 reductase/0.471
1ja0FADNADPH--cytochrome P450 reductase/0.470
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.470
1sq5ADPPantothenate kinase2.7.1.330.470
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.470
2ifaFMNUncharacterized protein/0.470
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.470
3ojwFMNNADPH--cytochrome P450 reductase/0.470
1g63FMNEpidermin decarboxylase4.1.10.469
1rvvINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.469
2jl1NAPTriphenylmethane reductase/0.469
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.469
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.469
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.468
1o86LPRAngiotensin-converting enzyme3.2.10.468
2hxzH7JCathepsin S3.4.22.270.468
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3q9bB3NAcetylpolyamine amidohydrolase/0.468
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.468
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.468
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.468
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.467
2qimZEAClass 10 plant pathogenesis-related protein/0.467
2wzySQXSoluble acetylcholine receptor/0.467
2x06NADL-sulfolactate dehydrogenase/0.467
2x9dITCTetracycline repressor protein class D/0.467
3ce0P34Poly [ADP-ribose] polymerase 32.4.2.300.467
3qe2FMNNADPH--cytochrome P450 reductase/0.467
3rviRVIBeta-secretase 13.4.23.460.467
4omaLCSMethionine gamma-lyase/0.467
1tilATPAnti-sigma F factor/0.466
2aouCQAHistamine N-methyltransferase2.1.1.80.466
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.466
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.466
4kxjP34Nucleoprotein/0.466
1yhjR6CPyridoxal kinase2.7.1.350.465
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.465
2w02ATPAcsD/0.465
2zsaADPPantothenate kinase2.7.1.330.465
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.465
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.464
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.464
2uxuNARHTH-type transcriptional regulator TtgR/0.464
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.464
3s5wFADL-ornithine N(5)-monooxygenase/0.464
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.464
4j7gTRHPCZA361.3/0.464
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.464
1c9wNAPAldose reductase-related protein 2/0.463
1pl6572Sorbitol dehydrogenase1.1.1.140.463
2bn4FMNNADPH--cytochrome P450 reductase/0.463
2e0nSAHPrecorrin-2 C20-methyltransferase/0.463
2gl0ADNUncharacterized protein/0.463
2hp2KE4Glutamate-1-semialdehyde 2,1-aminomutase5.4.3.80.463
4n4v2GYTankyrase-12.4.2.300.463
4pl0ANPMicrocin-J25 export ATP-binding/permease protein McjD/0.463
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.462
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
2a2xNA9Prothrombin3.4.21.50.462
2ed3SAHDiphthine synthase/0.462
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.462
3sfy3FYUncharacterized protein/0.462
4bfxZVXPantothenate kinase2.7.1.330.462
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
1dgfNDPCatalase1.11.1.60.461
1jdzFMBPurine nucleoside phosphorylase/0.461
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
2rc5FADFerredoxin--NADP reductase/0.461
2uxhQUEHTH-type transcriptional regulator TtgR/0.461
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
4usrFADMonooxygenase/0.461
5ah5LSSLeucine--tRNA ligase/0.461
1nqw5YL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.460
1vbmYSATyrosine--tRNA ligase6.1.1.10.460
1yw9A84Methionine aminopeptidase 2/0.460
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.460
2r8oT5XTransketolase 1/0.460
2w6pOA4Biotin carboxylase6.3.4.140.460
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.460
4gv25MEPoly [ADP-ribose] polymerase 32.4.2.300.460
4y9rFADNADPH--cytochrome P450 reductase/0.460
5irnADPNucleotide binding oligomerization domain containing 2/0.460
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.459
1qzyTDEMethionine aminopeptidase 2/0.459
2g226IGRenin3.4.23.150.459
3busSAHDemethylrebeccamycin-D-glucose O-methyltransferase/0.459
3pqbVGPPutative oxidoreductase/0.459
3u4o08EGenome polyprotein2.7.7.480.459
4lcw1VYMajor histocompatibility complex class I-related gene protein/0.459
4ypuSAMHistone-lysine N-methyltransferase ASH1L2.1.1.430.459
1g60SAMModification methylase MboII2.1.1.720.458
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1s4oGDPGlycolipid 2-alpha-mannosyltransferase/0.458
2w6cBM4Acetylcholinesterase3.1.1.70.458
3anmSYD1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.458
3h3r14HCollagen type IV alpha-3-binding protein/0.458
3h3t16HCollagen type IV alpha-3-binding protein/0.458
3n39FMNProtein NrdI/0.458
3r7kFDAProbable acyl CoA dehydrogenase/0.458
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.458
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.458
4drhRAPSerine/threonine-protein kinase mTOR2.7.11.10.458
4drhRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.458
4fkzUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.458
4yaw2AMNADPH--cytochrome P450 reductase/0.458
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.457
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.457
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.457
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3af3GCPPantothenate kinase2.7.1.330.457
3b03VNRIsopentenyl-diphosphate delta-isomerase/0.457
3c4hDRLPoly [ADP-ribose] polymerase 32.4.2.300.457
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3hggCHDCmeR/0.457
4df2FMNNADPH dehydrogenase/0.457
4frkDWDBeta-secretase 13.4.23.460.457
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.457
4jtqFLPAldo-keto reductase family 1 member C2/0.457
4xbjIN5Alanine racemase, biosynthetic/0.457
1fwmCB3Thymidylate synthase/0.456
1lnmDTXBilin-binding protein/0.456
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.456
1x1dSAHC-20 methyltransferase/0.456
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.456
2ga2A19Methionine aminopeptidase 2/0.456
2gv8NDPThiol-specific monooxygenase1.14.130.456
2ikuLIYRenin3.4.23.150.456
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.456
2xlpFADPutative flavin-containing monooxygenase/0.456
2xytTC9Soluble acetylcholine receptor/0.456
2zevB71Geranylgeranyl pyrophosphate synthase/0.456
3fktSIIBeta-secretase 13.4.23.460.456
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.456
3hl0NADMaleylacetate reductase/0.456
3qfsFADNADPH--cytochrome P450 reductase/0.456
3qwbNDPProbable quinone oxidoreductase1.6.5.50.456
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.456
4bfwZVWPantothenate kinase2.7.1.330.456
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.456
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
4qaiFMNNADPH dehydrogenase/0.456
1dghNDPCatalase1.11.1.60.455
1j8qFMNFlavodoxin/0.455
1l2tATPUncharacterized ABC transporter ATP-binding protein MJ0796/0.455
1p33MTXPteridine reductase 11.5.1.330.455
1x27ASP_ASP_TYR_VAL_PTRTyrosine-protein kinase Lck2.7.10.20.455
2b82ADNClass B acid phosphatase3.1.3.20.455
2g1n1IGRenin3.4.23.150.455
2piaFMNPhthalate dioxygenase reductase/0.455
3aezGDPPantothenate kinase2.7.1.330.455
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.455
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.455
4hhy15RPoly [ADP-ribose] polymerase 12.4.2.300.455
4j0t6T9Beta-secretase 13.4.23.460.455
4krs1SXTankyrase-12.4.2.300.455
1hi0GTPRNA-directed RNA polymerase2.7.7.480.454
2ea4F79Methionine aminopeptidase 2/0.454
2x95X95Angiotensin-converting enzyme3.4.15.10.454
3ekuCY9Actin-5C/0.454
3ivcFG4Pantothenate synthetase6.3.2.10.454
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3zeiAWHO-acetylserine sulfhydrylase/0.454
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.454
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.454
1amoFADNADPH--cytochrome P450 reductase/0.453
1lvu9PPPurine nucleoside phosphorylase2.4.2.10.453
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.453
1yw8A75Methionine aminopeptidase 2/0.453
2g1r3IGRenin3.4.23.150.453
2g6pHM2Methionine aminopeptidase 1/0.453
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.453
3ba6AN2Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.453
3hiiPNTAmiloride-sensitive amine oxidase [copper-containing]/0.453
3p0fBAUUridine phosphorylase 22.4.2.30.453
3ufl508Beta-secretase 13.4.23.460.453
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.453
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.453
4e2yJHZMethyltransferase/0.453
4e7r0NWProthrombin3.4.21.50.453
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.453
4to1DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.453
1al8DHPPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.452
1wkhPPE[LysW]-aminoadipate semialdehyde transaminase/0.452
2gesCOKPantothenate kinase2.7.1.330.452
3e6eDCSAlanine racemase/0.452
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.452
3zhtTD9Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.452
4dyp0MSNucleoprotein/0.452
4g090VDHistidinol dehydrogenase/0.452
4xnw2IDP2Y purinoceptor 1/0.452
1ohhANPATP synthase subunit alpha, mitochondrial/0.451
1ohhANPATP synthase subunit beta, mitochondrial3.6.3.140.451
1ry0PG2Aldo-keto reductase family 1 member C3/0.451
2bpoFADNADPH--cytochrome P450 reductase/0.451
3buzTADIota toxin component Ia/0.451
3frkTQPQdtB/0.451
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.451
3rtnRTNBeta-secretase 13.4.23.460.451
3v2uATPProtein GAL3/0.451
4b4vL34Bifunctional protein FolD/0.451
4driRAPSerine/threonine-protein kinase mTOR2.7.11.10.451
4driRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.451
4dvi2IWTankyrase-12.4.2.300.451
4dya0MFNucleoprotein/0.451
4m9aFDAAcyl-CoA dehydrogenase/0.451
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.451
1nm6L86Prothrombin3.4.21.50.450
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
1zdwFLVPrenyltransferase/0.450
2clfF6FTryptophan synthase alpha chain/0.450
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.450
2iibC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.450
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
3ckqUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.450
3gnvXNZGenome polyprotein2.7.7.480.450
3icpNADNAD-dependent epimerase/dehydratase/0.450
3ojxFMNNADPH--cytochrome P450 reductase/0.450
4e0u0MVCyclic dipeptide N-prenyltransferase/0.450
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.450
4hfp15UProthrombin3.4.21.50.450
4nv1TYDFormyl transferase/0.450
4p9cDCMDeoxycytidylate deaminase/0.450
4x9dU5PUncharacterized protein MJ1435/0.450
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
2g247IGRenin3.4.23.150.449
2v5uFMNFlavodoxin/0.449
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.449
2zcvNDPQuinone oxidoreductase 21.6.5.20.449
3cow52HPantothenate synthetase6.3.2.10.449
3intFDAUDP-galactopyranose mutase5.4.99.90.449
3m4p4ADAsparaginyl-tRNA synthetase, putative/0.449
3ts1TYATyrosine--tRNA ligase6.1.1.10.449
3v0p4GWHisto-blood group ABO system transferase/0.449
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.449
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.449
4b65FADL-ornithine N(5)-monooxygenase/0.449
4cdmFO1Deoxyribodipyrimidine photolyase/0.449
4frjDWBBeta-secretase 13.4.23.460.449
4h6pFMNChromate reductase/0.449
4ktl1CQCytochrome P450/0.449
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.449
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.449
1amoFMNNADPH--cytochrome P450 reductase/0.448
1fmlRTLRetinol dehydratase/0.448
1gky5GPGuanylate kinase2.7.4.80.448
2ejvNADL-threonine 3-dehydrogenase/0.448
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.448
2oatPFMOrnithine aminotransferase, mitochondrial2.6.1.130.448
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
3qfrFMNNADPH--cytochrome P450 reductase/0.448
4araC56Acetylcholinesterase3.1.1.70.448
4h1e10JBeta-secretase 13.4.23.460.448
4j7hTRHPCZA361.3/0.448
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.448
4m0f1YKAcetylcholinesterase3.1.1.70.448
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.448
1bjkFADFerredoxin--NADP reductase1.18.1.20.447
1fwyUD1Bifunctional protein GlmU/0.447
1odcA8BAcetylcholinesterase3.1.1.70.447
1r58AO5Methionine aminopeptidase 2/0.447
2clmF6FTryptophan synthase alpha chain/0.447
3ai0PNWBeta-glucosidase/0.447
3kp4MIITranscriptional regulator TcaR/0.447
3lpkZ76Beta-secretase 13.4.23.460.447
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3pdnSFGHistone-lysine N-methyltransferase SMYD32.1.1.430.447
3wqmB29Diterpene synthase3.1.7.80.447
4bj9UHBTankyrase-22.4.2.300.447
4gv7MEWPoly [ADP-ribose] polymerase 12.4.2.300.447
4nesUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.447
4oviN01Phenylacetone monooxygenase1.14.13.920.447
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1k9sFM1Purine nucleoside phosphorylase DeoD-type/0.446
1r5gAO1Methionine aminopeptidase 2/0.446
1thz326Bifunctional purine biosynthesis protein PURH2.1.2.30.446
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.446
2oazI96Methionine aminopeptidase 2/0.446
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3mauEXTPutative sphingosine-1-phosphate lyase/0.446
4c717RD3-oxoacyl-ACP synthase/0.446
4dyn0MRNucleoprotein/0.446
4j0v1H7Beta-secretase 13.4.23.460.446
4jlm1NNDeoxycytidine kinase2.7.1.740.446
4relKMPGlycosyltransferase/0.446
4ts7ADPPurine phosphoribosyltransferase (GpT-1)/0.446
1e79ATPATP synthase subunit alpha, mitochondrial/0.445
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.445
1qg0FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.445
1x1aSAMC-20 methyltransferase/0.445
1x8lOXRRetinol dehydratase/0.445
2ea2F77Methionine aminopeptidase 2/0.445
2g1s4IGRenin3.4.23.150.445
2qw034Z4-chlorobenzoyl CoA ligase/0.445
3dr7GPDGDP-perosamine synthase/0.445
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3qviK95HAP protein/0.445
4b63FADL-ornithine N(5)-monooxygenase/0.445
4b65NDPL-ornithine N(5)-monooxygenase/0.445
4h3i10VBeta-secretase 13.4.23.460.445
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.445
4psbGA3Cytokinin-specific binding protein/0.445
4rvgTYDD-mycarose 3-C-methyltransferase/0.445
1d3dBZTProthrombin3.4.21.50.444
1txzAPRProbable ADP-ribose 1''-phosphate phosphatase YML087W3.1.3.840.444
1u1jC2F5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 12.1.1.140.444
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.444
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.444
2hveADPNucleoside diphosphate kinase A2.7.4.60.444
2zevIPEGeranylgeranyl pyrophosphate synthase/0.444
3arvSAUChitinase A/0.444
3cr0809Wee1-like protein kinase2.7.10.20.444
3cvkN34Genome polyprotein2.7.7.480.444
3l3mA92Poly [ADP-ribose] polymerase 12.4.2.300.444
3ukoNADAlcohol dehydrogenase class-3/0.444
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.444
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.444
4nbjD3YD-tyrosyl-tRNA(Tyr) deacylase/0.444
4req5ADMethylmalonyl-CoA mutase large subunit5.4.99.20.444
5cxv0HKMuscarinic acetylcholine receptor M1/0.444
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.443
1cnfFADNitrate reductase [NADH]1.7.1.10.443
1j9zFADNADPH--cytochrome P450 reductase/0.443
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.443
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.443
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.443
1xe55FEPlasmepsin-23.4.23.390.443
2cf9348Prothrombin3.4.21.50.443
2emuSAHDiphthine synthase/0.443
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.443
2pucGUNHTH-type transcriptional repressor PurR/0.443
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3e4aQIXInsulin-degrading enzyme3.4.24.560.443
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.443
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.443
4fqsLYAThymidylate synthase ThyA/0.443
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.443
4ips1G4Mycocyclosin synthase1.14.21.90.443
4mlp2CXCryptochrome-2/0.443
4rh10TTSpore photoproduct lyase/0.443
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.443
3d4sTIMBeta-2 adrenergic receptor/0.443
1jf0CZHObelin/0.442
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.442
1ndzFR5Adenosine deaminase3.5.4.40.442
1oxoIK2Aspartate aminotransferase, mitochondrial2.6.1.10.442
1pkfEPDEpothilone C/D epoxidase1.140.442
1tllFMNNitric oxide synthase, brain1.14.13.390.442
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.442
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.442
2bf4FADNADPH--cytochrome P450 reductase/0.442
2dshSAHDiphthine synthase/0.442
2e94364Geranylgeranyl pyrophosphate synthase/0.442
2iko7IGRenin3.4.23.150.442
2uxoTACHTH-type transcriptional regulator TtgR/0.442
2xq0BESLeukotriene A-4 hydrolase homolog3.3.2.60.442
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.442
3biz61EWee1-like protein kinase2.7.10.20.442
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3g5hYTTMycocyclosin synthase1.14.21.90.442
3iocA5DPantothenate synthetase6.3.2.10.442
3qt62P0Mevalonate diphosphate decarboxylase/0.442
4eb7PLPCysteine desulfurase IscS 2/0.442
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.442
4phlPILPhosphodiesterase/0.442
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.442
4z87GDPInosine-5'-monophosphate dehydrogenase/0.442
5jqhCAUBeta-2 adrenergic receptor/0.442
5d6lCAUBeta-2 adrenergic receptor/0.442
1cq6PY4Aspartate aminotransferase2.6.1.10.441
1n2iPAJPantothenate synthetase6.3.2.10.441
1n75ATPGlutamate--tRNA ligase6.1.1.170.441
1odnAPVIsopenicillin N synthase1.21.3.10.441
1q83TZ5Acetylcholinesterase3.1.1.70.441
1ygkRRCPyridoxal kinase2.7.1.350.441
1z71L17Prothrombin3.4.21.50.441
2bqzSAHN-lysine methyltransferase KMT5A/0.441
2dv4SAHDiphthine synthase/0.441
2gpjFADSiderophore-interacting protein/0.441
2v57PRLTetR family transcriptional regulator/0.441
3ioeA7DPantothenate synthetase6.3.2.10.441
3irhDTPHD domain protein/0.441
3jzdNADMaleylacetate reductase/0.441
3ndjJHZMethyltransferase/0.441
3otwCOAPhosphopantetheine adenylyltransferase/0.441
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.441
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.441
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4eqrCOACoenzyme A disulfide reductase/0.441
4ey7E20Acetylcholinesterase3.1.1.70.441
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.441
4ke11R6Beta-secretase 13.4.23.460.441
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.441
4xmxBESAminopeptidase N3.4.11.20.441
1e66HUXAcetylcholinesterase3.1.1.70.440
1h36R88Squalene--hopene cyclase4.2.1.1290.440
1h8hADPATP synthase subunit alpha, mitochondrial/0.440
1h8hADPATP synthase subunit beta, mitochondrial3.6.3.140.440
1jwtBLIProthrombin3.4.21.50.440
1krhFADBenzoate 1,2-dioxygenase electron transfer component1.18.1.30.440
1obnASVIsopenicillin N synthase1.21.3.10.440
1qruATPGlutamine--tRNA ligase6.1.1.180.440
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.440
2uuk897Prothrombin3.4.21.50.440
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.440
3fvqATPFe(3+) ions import ATP-binding protein FbpC/0.440
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.440
3l3lL3LPoly [ADP-ribose] polymerase 12.4.2.300.440
3pndFADFAD:protein FMN transferase/0.440
4acuQN7Beta-secretase 13.4.23.460.440
4ef9FMNDihydroorotate dehydrogenase (fumarate)/0.440
4l6s1WQPoly [ADP-ribose] polymerase 12.4.2.300.440
4n3r2GUTankyrase-12.4.2.300.440
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.440
4nv10FXFormyl transferase/0.440
5dsyUHBPoly [ADP-ribose] polymerase 22.4.2.300.440