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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3jq8DX3Pteridine reductase, putative

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3jq8DX3Pteridine reductase, putative/1.000
3jqbDX6Pteridine reductase, putative/0.568
2x9vTMQPteridine reductase/0.551
3jq9AX1Pteridine reductase, putative/0.551
2vz0D64Pteridine reductase/0.549
3jq7DX2Pteridine reductase, putative/0.544
3jqgAX6Pteridine reductase, putative/0.544
2yhuWHFPteridine reductase/0.537
3jq6DX1Pteridine reductase, putative/0.535
3bmqAX5Pteridine reductase/0.531
3bmcFOLPteridine reductase/0.522
3mcvMCVPteridine reductase/0.513
1p33MTXPteridine reductase 11.5.1.330.501
2x9gLYAPteridine reductase/0.488
1mxfMTXPutative pteridine reductase 2/0.483
2bfmTOPPteridine reductase 11.5.1.330.470
1e7wMTXPteridine reductase 11.5.1.330.456
2wd7VGDPteridine reductase/0.454
3bmnAX3Pteridine reductase/0.445