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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3iogSDFMetallo-beta-lactamase type 2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3iogSDFMetallo-beta-lactamase type 2/1.000
3akn11DFatty acid-binding protein, intestinal/0.538
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.527
2qdsMCOMetallo-beta-lactamase type 2/0.521
4a83DXCMajor pollen allergen Bet v 1-A/0.518
4a81DXCMajor pollen allergen Bet v 1-A/0.509
3otwCOAPhosphopantetheine adenylyltransferase/0.506
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.504
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.503
4dc0NDPPutative ketoacyl reductase1.3.10.502
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.501
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.501
1xddAAYIntegrin alpha-L/0.500
1i5cADPChemotaxis protein CheA2.7.13.30.498
3u9eCOALmo1369 protein/0.497
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.497
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.496
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.496
2g247IGRenin3.4.23.150.495
3ixp834Ecdysone receptor/0.495
4hl1ZZ7Metallo-beta-lactamase type 2/0.495
1ay0TPPTransketolase 12.2.1.10.494
1hb3SCVIsopenicillin N synthase1.21.3.10.494
3akm11DFatty acid-binding protein, intestinal/0.494
3lqfNADGalactitol dehydrogenase/0.494
3sp9IL2Peroxisome proliferator-activated receptor delta/0.494
3gwfNAPCyclohexanone monooxygenase/0.493
1h9zRWFSerum albumin/0.492
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.492
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.492
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.492
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.492
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.492
4iah1DXAlr2278 protein/0.492
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.491
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.490
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.490
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.490
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.489
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.488
2rhgIGPTryptophan synthase alpha chain/0.488
3fhxPLPPyridoxal kinase2.7.1.350.488
1cjvFOKAdenylate cyclase type 2/0.487
1cjvFOKAdenylate cyclase type 5/0.487
2d29FADAcyl-CoA dehydrogenase/0.487
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.486
2ejzSAHDiphthine synthase/0.486
3c14FOKAdenylate cyclase type 2/0.486
3c14FOKAdenylate cyclase type 5/0.486
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.486
1cf3FADGlucose oxidase1.1.3.40.485
1hb1OCVIsopenicillin N synthase1.21.3.10.485
1osvCHCBile acid receptor/0.485
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.485
4psbGA3Cytokinin-specific binding protein/0.485
4a802ANMajor pollen allergen Bet v 1-A/0.484
5stdUNNScytalone dehydratase4.2.1.940.484
1fmjRTLRetinol dehydratase/0.483
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.483
1obnASVIsopenicillin N synthase1.21.3.10.483
1ot7IU5Bile acid receptor/0.483
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.483
4lcg1WMUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.483
1i59ADPChemotaxis protein CheA2.7.13.30.482
2onmADPAldehyde dehydrogenase, mitochondrial1.2.1.30.482
2zbaZBATrichothecene 3-O-acetyltransferase/0.482
3uayADNPurine nucleoside phosphorylase DeoD-type/0.482
4kxjP34Nucleoprotein/0.482
4v2gITCTetracycline repressor protein class D/0.482
1bk0ACVIsopenicillin N synthase1.21.3.10.481
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.481
1bwsNDPGDP-L-fucose synthase/0.480
1qiqACCIsopenicillin N synthase1.21.3.10.480
2rhrEMOPutative ketoacyl reductase1.3.10.480
3zkyWT4Isopenicillin N synthase1.21.3.10.480
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.480
2iviACWIsopenicillin N synthase1.21.3.10.479
2jb4A14Isopenicillin N synthase1.21.3.10.479
4iarERM5-hydroxytryptamine receptor 1B/0.479
1kt3RTLRetinol-binding protein 4/0.478
1o1vTCHGastrotropin/0.478
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.478
3tfq07MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.478
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.478
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.478
1tl7FOKAdenylate cyclase type 2/0.477
1tl7FOKAdenylate cyclase type 5/0.477
2npfMOUElongation factor 2/0.477
4a8v2ANMajor pollen allergen Bet v 1-J/0.477
4bfwZVWPantothenate kinase2.7.1.330.477
4dbzNDPPutative ketoacyl reductase1.3.10.477
4hl2ZZ7Metallo-beta-lactamase type 2/0.477
4uugPXGBranched-chain amino acid aminotransferase, putative/0.477
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.477
4zu44TGWxcM-like protein/0.477
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.477
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.476
1udaUFGUDP-glucose 4-epimerase5.1.3.20.476
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.476
2c0cNAPProstaglandin reductase 310.476
4relKMPGlycosyltransferase/0.476
5a3bAPRSIR2 family protein/0.476
1m13HYFNuclear receptor subfamily 1 group I member 2/0.475
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.475
2hk9NAPShikimate dehydrogenase (NADP(+))/0.475
2nnqT4BFatty acid-binding protein, adipocyte/0.475
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.475
4exsX8ZMetallo-beta-lactamase type 2/0.475
4ipw1G7Mycocyclosin synthase1.14.21.90.475
4tmcFMNOld yellow enzyme/0.475
1q45FMN12-oxophytodienoate reductase 31.3.1.420.474
1txtCAAHMG-CoA synthase/0.474
2rqfJH3Hemolymph juvenile hormone binding protein/0.474
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.474
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.474
3ha5SFGHydroxymycolate synthase MmaA42.1.10.474
3l6jZ90Alr2278 protein/0.474
1z4uPH9Polyprotein/0.473
2cy0NAPShikimate dehydrogenase (NADP(+))/0.473
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.473
3h3t16HCollagen type IV alpha-3-binding protein/0.473
3imgBZ2Pantothenate synthetase6.3.2.10.473
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.473
3vtbTKAVitamin D3 receptor/0.473
4a6rTA8Probable aminotransferase/0.473
4cdmFO1Deoxyribodipyrimidine photolyase/0.473
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.473
4mihFADPyranose 2-oxidase1.1.3.100.473
1culFOKAdenylate cyclase type 2/0.472
1culFOKAdenylate cyclase type 5/0.472
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.472
2ea4F79Methionine aminopeptidase 2/0.472
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.472
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.472
3fhxPXLPyridoxal kinase2.7.1.350.472
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.472
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.472
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.472
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.472
1x7hNDPPutative ketoacyl reductase1.3.10.471
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.471
3cehAVEGlycogen phosphorylase, liver form2.4.1.10.471
4gd40WSLysine-specific demethylase 4A1.14.110.471
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
4nbwNADShort-chain dehydrogenase/reductase SDR/0.471
1xpqFADPolyamine oxidase FMS1/0.470
2ohvNHLGlutamate racemase/0.470
2po7CHDFerrochelatase, mitochondrial4.99.1.10.470
3ogkOGKCoronatine-insensitive protein 1/0.470
3sl2ATPSensor histidine kinase WalK/0.470
3vtdTKDVitamin D3 receptor/0.470
3zhrTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.470
4jqh1MFAlr2278 protein/0.470
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.470
1cjuFOKAdenylate cyclase type 2/0.469
1cjuFOKAdenylate cyclase type 5/0.469
1dgbNDPCatalase1.11.1.60.469
1gky5GPGuanylate kinase2.7.4.80.469
1y6oMJIPhospholipase A2, major isoenzyme3.1.1.40.469
1zg32HIIsoflavone 4'-O-methyltransferase/0.469
2futH1SHeparin and heparin-sulfate lyase/0.469
4l4xNDPAmphI/0.469
4mlp2CXCryptochrome-2/0.469
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.469
4zowCLMMultidrug transporter MdfA/0.469
1kt6RTLRetinol-binding protein 4/0.468
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.468
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.468
2xveFADPutative flavin-containing monooxygenase/0.468
3csdEMOPutative ketoacyl reductase1.3.10.468
3h3qH13Collagen type IV alpha-3-binding protein/0.468
3junAJDPhenazine biosynthesis protein A/B/0.468
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3zoiM2WIsopenicillin N synthase1.21.3.10.468
4cukNAID-lactate dehydrogenase/0.468
4fv7E94Mitogen-activated protein kinase 12.7.11.240.468
4g3jVNTLanosterol 14-alpha-demethylase/0.468
4i1iNADMalate dehydrogenase/0.468
4mv1ADPBiotin carboxylase6.3.4.140.468
4q0kGA3Phytohormone-binding protein/0.468
1kt7RTLRetinol-binding protein 4/0.467
1u1cBAUUridine phosphorylase2.4.2.30.467
2bu9HFVIsopenicillin N synthase1.21.3.10.467
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.467
3stdMQ0Scytalone dehydratase4.2.1.940.467
4iae1DXAlr2278 protein/0.467
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.467
4uymVOR14-alpha sterol demethylase Cyp51B/0.467
1bmfADPATP synthase subunit alpha, mitochondrial/0.466
1bmfADPATP synthase subunit beta, mitochondrial3.6.3.140.466
1cjtFOKAdenylate cyclase type 2/0.466
1cjtFOKAdenylate cyclase type 5/0.466
1cqp803Integrin alpha-L/0.466
1kt4RTLRetinol-binding protein 4/0.466
1nytNAPShikimate dehydrogenase (NADP(+))/0.466
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.466
2g1n1IGRenin3.4.23.150.466
2il2LIXRenin3.4.23.150.466
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.466
2zlaVDBVitamin D3 receptor/0.466
3gwfFADCyclohexanone monooxygenase/0.466
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.466
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.466
4a862ANMajor pollen allergen Bet v 1-A/0.466
4bb3KKAIsopenicillin N synthase1.21.3.10.466
4rh10TTSpore photoproduct lyase/0.466
1odcA8BAcetylcholinesterase3.1.1.70.465
2a94AP0L-lactate dehydrogenase1.1.1.270.465
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.465
2vqoTFGHistone deacetylase 43.5.1.980.465
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.465
3pqbVGPPutative oxidoreductase/0.465
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.465
3zhqTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.465
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.465
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.465
4bfzZVZPantothenate kinase2.7.1.330.465
4ocvANPAminoglycoside phosphotransferase/0.465
4oztP1AEcdysone receptor, putative/0.465
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.465
5fm7ADPRuvB-like helicase/0.465
1cjkFOKAdenylate cyclase type 2/0.464
1cjkFOKAdenylate cyclase type 5/0.464
1h50FMNPentaerythritol tetranitrate reductase/0.464
1l8qADPChromosomal replication initiator protein DnaA/0.464
1oyaFMNNADPH dehydrogenase 11.6.99.10.464
1rf7DHFDihydrofolate reductase1.5.1.30.464
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.464
1zdwFLVPrenyltransferase/0.464
2ghlLIBMitogen-activated protein kinase 14/0.464
2gjlFMNNitronate monooxygenase1.13.12.160.464
3ahiHTLProbable phosphoketolase/0.464
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.464
3i2834NBifunctional epoxide hydrolase 23.3.2.100.464
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
3s1dZIRCytokinin dehydrogenase 11.5.99.120.464
1cs4FOKAdenylate cyclase type 2/0.463
1cs4FOKAdenylate cyclase type 5/0.463
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.463
1fxfMJIPhospholipase A2, major isoenzyme3.1.1.40.463
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.463
2emuSAHDiphthine synthase/0.463
2fj1CTCTetracycline repressor protein class D/0.463
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.463
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.463
2r59PH0Leukotriene A-4 hydrolase3.3.2.60.463
2rlcCHDCholoylglycine hydrolase3.5.1.240.463
2y60M8FIsopenicillin N synthase1.21.3.10.463
2yj5ATPCopper-transporting ATPase/0.463
3bg7FADPyranose 2-oxidase/0.463
3ddw055Glycogen phosphorylase, liver form2.4.1.10.463
3fp0FP015-O-acetyltransferase/0.463
3fr5I4AFatty acid-binding protein, adipocyte/0.463
3lu1NADUDP-N-acetylglucosamine 4-epimerase/0.463
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.463
3p8iFMNPentaerythritol tetranitrate reductase/0.463
3v0p4GWHisto-blood group ABO system transferase/0.463
3wtkTH4Acetylcholine-binding protein/0.463
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.463
4ambDUDPutative glycosyl transferase/0.463
4da7AC2Purine nucleoside phosphorylase DeoD-type2.4.2.10.463
4dptAGSMevalonate diphosphate decarboxylase/0.463
4qe6JN3Bile acid receptor/0.463
4rnxFMNNADPH dehydrogenase 11.6.99.10.463
4xwtU5PRibonuclease J/0.463
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
1i5bANPChemotaxis protein CheA2.7.13.30.462
1x1bSAHC-20 methyltransferase/0.462
1x8lOXRRetinol dehydratase/0.462
1zeoC01Peroxisome proliferator-activated receptor gamma/0.462
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.462
3bsyACOUDP-N-acetylbacillosamine N-acetyltransferase2.3.1.2030.462
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
3il1B5DGlutamate receptor 2/0.462
3k4nFADPyranose 2-oxidase/0.462
3pm1ETHTH-type transcriptional regulator QacR/0.462
3wv9FEGHmd co-occurring protein HcgE/0.462
4bfvZVVPantothenate kinase2.7.1.330.462
4ejvLCLTranscriptional regulator TcaR/0.462
4i6gFADCryptochrome-2/0.462
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.462
4jlm1NNDeoxycytidine kinase2.7.1.740.462
4l0qNADAlcohol dehydrogenase class-3/0.462
4pd6URINucleoside permease/0.462
4qi5FADCellobiose dehydrogenase/0.462
5bn3ADPV-type ATP synthase alpha chain/0.462
5bn3ADPNEQ263/0.462
1dd6MCIMetallo-beta-lactamase type 2/0.461
1kquBR4Phospholipase A2, membrane associated/0.461
1mrqSTRAldo-keto reductase family 1 member C1/0.461
1x2hLPALipoate-protein ligase A6.3.1.200.461
1yb5NAPQuinone oxidoreductase1.6.5.50.461
1ygjRMCPyridoxal kinase2.7.1.350.461
2an9GDPGuanylate kinase2.7.4.80.461
2b0m201Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.461
2belCBOCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.461
2ejvNADL-threonine 3-dehydrogenase/0.461
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.461
2ignFADPyranose 2-oxidase/0.461
2lbaCHOFatty acid binding protein 6/0.461
2xszATPRuvB-like 23.6.4.120.461
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.461
3ibqATPPyridoxal kinase/0.461
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.461
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.461
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.461
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.461
4ure1PSCyclohexanol dehydrogenase/0.461
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.461
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.460
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.460
2cahNDPCatalase1.11.1.60.460
2ej2PPEBranched-chain amino acid aminotransferase (IlvE)/0.460
2oapANPType II secretion system protein (GspE-2)/0.460
2vkeTACTetracycline repressor protein class D/0.460
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.460
2zevB71Geranylgeranyl pyrophosphate synthase/0.460
3gw9VNILanosterol 14-alpha-demethylase/0.460
3n0cFADFlavin-dependent thymidylate synthase2.1.1.1480.460
3qiyQI1Botulinum neurotoxin type A3.4.24.690.460
3v2uATPProtein GAL3/0.460
3vt65YIVitamin D3 receptor/0.460
3vt9YI4Vitamin D3 receptor/0.460
4a6eASEAcetylserotonin O-methyltransferase2.1.1.40.460
4a99FADTetX family tetracycline inactivation enzyme/0.460
4e5yNDPGDP-L-fucose synthase1.1.1.2710.460
4kugNAD3-hydroxybutyryl-CoA dehydrogenase/0.460
4lsaBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.460
4ubuCOASteroid 3-ketoacyl-CoA thiolase/0.460
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.460
5hs1VORLanosterol 14-alpha demethylase/0.460
1bwlFMNNADPH dehydrogenase 11.6.99.10.459
1dhrNADDihydropteridine reductase1.5.1.340.459
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.459
1i59ANPChemotaxis protein CheA2.7.13.30.459
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.459
1kkq471Peroxisome proliferator-activated receptor alpha/0.459
1kziTHGThymidylate synthase/0.459
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.459
1nvtNAPShikimate dehydrogenase (NADP(+))/0.459
1x7gNAPPutative ketoacyl reductase1.3.10.459
2g1r3IGRenin3.4.23.150.459
2idoTMPDNA polymerase III subunit epsilon2.7.7.70.459
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.459
2xb5I7TTetracycline repressor protein class D/0.459
2xlpFADPutative flavin-containing monooxygenase/0.459
2yxuATPPyridoxal kinase2.7.1.350.459
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3fr4F8AFatty acid-binding protein, adipocyte/0.459
3mdmFJZCholesterol 24-hydroxylase/0.459
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4c3yFAD3-ketosteroid dehydrogenase/0.459
4ho6UTPGlucose-1-phosphate thymidylyltransferase/0.459
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.459
5c1mCLRMu-type opioid receptor/0.459
1fxsNAPGDP-L-fucose synthase/0.458
1g1aNADdTDP-glucose 4,6-dehydratase/0.458
1jkx138Phosphoribosylglycinamide formyltransferase/0.458
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
1pagFMPAntiviral protein I3.2.2.220.458
1r5hAO2Methionine aminopeptidase 2/0.458
1x1aSAMC-20 methyltransferase/0.458
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
2znoS44Peroxisome proliferator-activated receptor gamma/0.458
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.458
3ivcFG4Pantothenate synthetase6.3.2.10.458
3lkhLT6Genome polyprotein2.7.7.480.458
3oqfS51Renin3.4.23.150.458
3vg9ZMAAdenosine receptor A2a/0.458
3vt7VDXVitamin D3 receptor/0.458
3zbzOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.458
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.458
4fxy0W2Neurolysin, mitochondrial3.4.24.160.458
4ramPNMMetallo-beta-lactamase type 2/0.458
4rawZZ7Metallo-beta-lactamase type 2/0.458
1eioGCHGastrotropin/0.457
1gveNAPAflatoxin B1 aldehyde reductase member 310.457
1mczRMNBenzoylformate decarboxylase4.1.1.70.457
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.457
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1qorNDPQuinone oxidoreductase 1/0.457
1w06W05Isopenicillin N synthase1.21.3.10.457
2cndFADNitrate reductase [NADH]1.7.1.10.457
2p1t3TNRetinoic acid receptor RXR-alpha/0.457
2vkvTDCTetracycline repressor protein class D/0.457
3bi5FADPolyamine oxidase FMS1/0.457
3cndFADPolyamine oxidase FMS1/0.457
3iaeD7KBenzaldehyde lyase/0.457
3keqNADRedox-sensing transcriptional repressor Rex/0.457
3oev3OEProteasome subunit beta type-53.4.25.10.457
3oev3OEProteasome subunit beta type-63.4.25.10.457
3vf60H6Glucokinase2.7.1.20.457
4a87NARMajor pollen allergen Bet v 1-A/0.457
4dbs0HVAldo-keto reductase family 1 member C3/0.457
4eqxFADCoenzyme A disulfide reductase/0.457
4fhd0TTSpore photoproduct lyase/0.457
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.457
4l5b1UXDeoxycytidine kinase2.7.1.740.457
4o701QKBromodomain-containing protein 4/0.457
4q71FADBifunctional protein PutA/0.457
4ttiFMCPurine nucleoside phosphorylase DeoD-type/0.457
5ccyTMPPolymerase acidic protein/0.457
1n5qTNCActVA 6 protein/0.456
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.456
1xkdNAPIsocitrate dehydrogenase [NADP]/0.456
1yhjR6CPyridoxal kinase2.7.1.350.456
2e8hSAHDiphthine synthase/0.456
2gv8NDPThiol-specific monooxygenase1.14.130.456
2hveADPNucleoside diphosphate kinase A2.7.4.60.456
2pamTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.456
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.456
2vbdV10Isopenicillin N synthase1.21.3.10.456
2w03ADNAcsD/0.456
2xvq9DSSerum albumin/0.456
2y05RALProstaglandin reductase 1/0.456
3b6pTMPThree-prime repair exonuclease 13.1.11.20.456
3f03FMNPentaerythritol tetranitrate reductase/0.456
3r5yF42Uncharacterized protein/0.456
3wleNAD(R)-specific carbonyl reductase/0.456
3zhuTD8Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.456
3zk5Z18Cytochrome P450 monooxygenase PikC/0.456
4a84DXCMajor pollen allergen Bet v 1-A/0.456
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.456
4dpuAGSMevalonate diphosphate decarboxylase/0.456
4dpy2P0Mevalonate diphosphate decarboxylase/0.456
4dz5NAPAldo-keto reductase family 1 member C3/0.456
4e37NDPCatalase1.11.1.60.456
4g210VPVitamin D3 receptor A/0.456
4m83ERYOleandomycin glycosyltransferase2.4.10.456
4xbjIN5Alanine racemase, biosynthetic/0.456
4zj8SUVOrexin receptor type 1/0.456
1jd0AZMCarbonic anhydrase 124.2.1.10.455
1kvoOAPPhospholipase A2, membrane associated/0.455
1rftPXMPyridoxal kinase2.7.1.350.455
1thnADPAnti-sigma F factor/0.455
1u0hFOKAdenylate cyclase type 2/0.455
1u0hFOKAdenylate cyclase type 5/0.455
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2a9z26AAdenosine kinase2.7.1.200.455
2g0nGDPRas-related C3 botulinum toxin substrate 3/0.455
2h55DZ8Heat shock protein HSP 90-alpha/0.455
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.455
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.455
2w6oOA3Biotin carboxylase6.3.4.140.455
3af3GCPPantothenate kinase2.7.1.330.455
3atyFMNProstaglandin F2a synthase/0.455
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.455
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3vsxR32Renin3.4.23.150.455
4e0u0MVCyclic dipeptide N-prenyltransferase/0.455
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.455
4n1gCEIObelin/0.455
4twnB96Ephrin type-A receptor 32.7.10.10.455
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.455
4xiwAZMCarbonic anhydrase, alpha type/0.455
1bsvNDPGDP-L-fucose synthase/0.454
1e3eNAIAlcohol dehydrogenase 41.1.1.10.454
1gaxVAAValine--tRNA ligase6.1.1.90.454
1k7fIAVTryptophan synthase alpha chain/0.454
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.454
1rx8FOLDihydrofolate reductase1.5.1.30.454
2f2sCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.454
2fr1NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.454
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.454
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.454
2jizANPATP synthase subunit beta, mitochondrial3.6.3.140.454
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.454
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
2ozuACOHistone acetyltransferase KAT6A/0.454
2qimZEAClass 10 plant pathogenesis-related protein/0.454
2tctCTCTetracycline repressor protein class D/0.454
2vceU2FUDP-glycosyltransferase 72B1/0.454
2ym1FADPhenylacetone monooxygenase1.14.13.920.454
2zsiGA4Gibberellin receptor GID1A30.454
3bi2FADPolyamine oxidase FMS1/0.454
3cinNADMyo-inositol-1-phosphate synthase-related protein/0.454
3e8xNAPBH1520 protein/0.454
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.454
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.454
3nx2FERFerulic acid decarboxylase/0.454
3rbqGLY_ALA_GLY_DAOProtein unc-119 homolog A/0.454
4er6AW2Histone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.454
4gk2L66Ephrin type-A receptor 32.7.10.10.454
4ho9UTPGlucose-1-phosphate thymidylyltransferase/0.454
4jx1CAHCamphor 5-monooxygenase1.14.15.10.454
4r1lADPPhenylacetate-coenzyme A ligase/0.454
5ikqJMSProstaglandin G/H synthase 21.14.99.10.454
6gsxGPSGlutathione S-transferase Mu 12.5.1.180.454
1bwkFMNNADPH dehydrogenase 11.6.99.10.453
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.453
1yw8A75Methionine aminopeptidase 2/0.453
2abbFMNPentaerythritol tetranitrate reductase/0.453
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.453
2dsgSAHDiphthine synthase/0.453
2gjnFMNNitronate monooxygenase1.13.12.160.453
2ociTYCValacyclovir hydrolase3.10.453
2ok7FADFerredoxin--NADP reductase, apicoplast/0.453
2q9fC3SCholesterol 24-hydroxylase/0.453
2rh9IGPTryptophan synthase alpha chain/0.453
2xrlDXTTetracycline repressor protein class D/0.453
2xvfFADPutative flavin-containing monooxygenase/0.453
3c3xNAPEugenol synthase 11.1.1.3180.453
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.453
3f63GTXGlutathione transferase GST1-4/0.453
3h3r14HCollagen type IV alpha-3-binding protein/0.453
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.453
3hl0NADMaleylacetate reductase/0.453
3junAKDPhenazine biosynthesis protein A/B/0.453
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.453
3nxyD2HDihydrofolate reductase1.5.1.30.453
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.453
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.453
4bfyZVYPantothenate kinase2.7.1.330.453
4c1fX8ZMetallo-beta-lactamase type 2/0.453
4da6GA2Purine nucleoside phosphorylase DeoD-type2.4.2.10.453
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.453
4rujVDXVitamin D3 receptor A/0.453
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.453
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.453
1al7HSTPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.452
1blzACVIsopenicillin N synthase1.21.3.10.452
1if8SBSCarbonic anhydrase 24.2.1.10.452
1kqwRTLCellular retinol-binding protein type II/0.452
1o5rFR9Adenosine deaminase3.5.4.40.452
1qipGNBLactoylglutathione lyase4.4.1.50.452
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1rneC60Renin3.4.23.150.452
1u1gBBBUridine phosphorylase2.4.2.30.452
2bsxNOSPurine nucleoside phosphorylase/0.452
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.452
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.452
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.452
2jj2ADPATP synthase subunit alpha, mitochondrial/0.452
2jj2ADPATP synthase subunit beta, mitochondrial3.6.3.140.452
2jl1NAPTriphenylmethane reductase/0.452
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.452
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.452
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.452
3hk1B64Fatty acid-binding protein, adipocyte/0.452
3qizQI2Botulinum neurotoxin type A3.4.24.690.452
3vt8YI3Vitamin D3 receptor/0.452
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.452
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.452
4ia7BIVVitamin D3 receptor A/0.452
4to5DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.452
4u7wNDPMxaA/0.452
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.452
5e7oMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.452
5emhNAPIridoid synthase1.3.1.990.452
3emlZMAAdenosine receptor A2a/0.452
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.451
1dgfNDPCatalase1.11.1.60.451
1h74ADPHomoserine kinase2.7.1.390.451
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.451
1lluNADAlcohol dehydrogenase/0.451
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.451
1rfvADPPyridoxal kinase2.7.1.350.451
1uxjNADMalate dehydrogenase/0.451
1ve3SAMUncharacterized protein/0.451
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
2hdjNDPAldo-keto reductase family 1 member C2/0.451
2hsdNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.451
2igoFADPyranose 2-oxidase/0.451
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.451
2jizADPATP synthase subunit beta, mitochondrial3.6.3.140.451
2w6mOA1Biotin carboxylase6.3.4.140.451
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.451
3gfbNADL-threonine 3-dehydrogenase/0.451
3maaFKPAdenylate cyclase type 2/0.451
3maaFKPAdenylate cyclase type 5/0.451
3orfNADDihydropteridine reductase1.5.1.340.451
3p82FMNPentaerythritol tetranitrate reductase/0.451
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.451
4ceqQCHIntegrase/0.451
4eji0QACytochrome P450 2A131.14.14.10.451
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.451
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.451
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.451
4k6fNAPPutative Acetoacetyl-CoA reductase/0.451
4mdhNADMalate dehydrogenase, cytoplasmic1.1.1.370.451
4tx9AMZPhosphoribosyl isomerase A/0.451
4xbfFADLysine-specific histone demethylase 1A10.451
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.451
5js6NAD17-beta-hydroxysteroid dehydrogenase 141.1.10.451
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.450
1di8DTQCyclin-dependent kinase 22.7.11.220.450
1eirBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.450
1fmlRTLRetinol dehydratase/0.450
1o9bNAIQuinate/shikimate dehydrogenase/0.450
1pkfEPDEpothilone C/D epoxidase1.140.450
1vbiNADMalate/L-lactate dehydrogenase family protein/0.450
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
2g226IGRenin3.4.23.150.450
2nn7M29Carbonic anhydrase 14.2.1.10.450
2pauD5M5'-deoxynucleotidase YfbR/0.450
2x9dITCTetracycline repressor protein class D/0.450
2xtzGSPGuanine nucleotide-binding protein alpha-1 subunit/0.450
3djfBC3Purine nucleoside phosphorylase/0.450
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.450
3rj0BLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.450
3smkCW714-3-3 protein sigma/0.450
3tfyMET_LEU_GLY_PRON-alpha-acetyltransferase 502.3.10.450
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.450
4y8wSTRSteroid 21-hydroxylase/0.450
5cb3APRO-acetyl-ADP-ribose deacetylase/0.450
4s0vSUVOrexin receptor type 2/0.450
1db1VDXVitamin D3 receptor/0.449
1dghNDPCatalase1.11.1.60.449
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
1ry0PG2Aldo-keto reductase family 1 member C3/0.449
1towCRZFatty acid-binding protein, adipocyte/0.449
1x8b824Wee1-like protein kinase2.7.10.20.449
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.449
1ycfFMNNitric oxide reductase10.449
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.449
2g1o2IGRenin3.4.23.150.449
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.449
2o12FMNChorismate synthase/0.449
2oegUPGUDP-glucose pyrophosphorylase/0.449
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.449
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3c4vLIPD-inositol 3-phosphate glycosyltransferase2.4.1.2500.449
3kpzZNEVitamin D3 receptor/0.449
3l63CAMCamphor 5-monooxygenase1.14.15.10.449
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
3lu8IQXSerum albumin/0.449
3mjrAC2Deoxycytidine kinase2.7.1.740.449
3otqMZLBifunctional epoxide hydrolase 23.3.2.100.449
3p67FMNPentaerythritol tetranitrate reductase/0.449
3r7vZ02Cyclin-dependent kinase 22.7.11.220.449
3wqmB29Diterpene synthase3.1.7.80.449
4aosNAPSteroid monooxygenase/0.449
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.449
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.449
4e5j581Polymerase acidic protein/0.449
4m4922YL-lactate dehydrogenase A chain1.1.1.270.449
4nbuNAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.449
4rkdKETAminotransferase/0.449
5hg0SAMPantothenate synthetase/0.449
5jljGNPGTP-binding nuclear protein Ran/0.449
5jscFADPutative acyl-CoA dehydrogenase/0.449
3sn6P0GBeta-2 adrenergic receptor/0.449
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.448
1dirNADDihydropteridine reductase1.5.1.340.448
1dkfBMSRetinoic acid receptor alpha/0.448
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.448
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1ot7CHCBile acid receptor/0.448
1qoqIGPTryptophan synthase alpha chain/0.448
2gvdFKPAdenylate cyclase type 2/0.448
2gvdFKPAdenylate cyclase type 5/0.448
2kceD16Thymidylate synthase/0.448
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.448
2rkvZBATrichothecene 3-O-acetyltransferase/0.448
2v59LZKBiotin carboxylase6.3.4.140.448
2vb8TLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.448
2w4qCBWProstaglandin reductase 21.3.1.480.448
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.448
3cvkN34Genome polyprotein2.7.7.480.448
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3ll9ADPIsopentenyl phosphate kinase/0.448
3mqe416Prostaglandin G/H synthase 21.14.99.10.448
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3qt62P0Mevalonate diphosphate decarboxylase/0.448
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.448
3tm5SFGUncharacterized protein/0.448
4do30LAFatty-acid amide hydrolase 13.5.1.990.448
4eh9IRGMitogen-activated protein kinase 14/0.448
4gdcNDPUDP-galactopyranose mutase/0.448
4ia1BIVVitamin D3 receptor A/0.448
4p9dTMPDeoxycytidylate deaminase/0.448
4rrgA3TThreonine--tRNA ligase6.1.1.30.448
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.448
5bv3M7Gm7GpppX diphosphatase3.6.1.590.448
5la6GDPTubulin beta-2B chain/0.448
1adfTADAlcohol dehydrogenase E chain1.1.1.10.447
1b48HAGGlutathione S-transferase A42.5.1.180.447
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.447
1hdrNADDihydropteridine reductase1.5.1.340.447
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1qinGIPLactoylglutathione lyase4.4.1.50.447
1rj6AZMCarbonic anhydrase 144.2.1.10.447
1uzwCDHIsopenicillin N synthase1.21.3.10.447
1wxyFRKAdenosine deaminase3.5.4.40.447
1xjqADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 12.7.1.250.447
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.447
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
2iko7IGRenin3.4.23.150.447
2vyqFADFerredoxin--NADP reductase1.18.1.20.447
2xlsFADPutative flavin-containing monooxygenase/0.447
2zs9ADPPantothenate kinase2.7.1.330.447
3atzFMNProstaglandin F2a synthase/0.447
3br3ETHTH-type transcriptional regulator QacR/0.447
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
3ckqUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.447
3gueUPGUTP-glucose-1-phosphate uridylyltransferase 2, putative/0.447
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.447
3l8yGNPGTPase HRas/0.447
3vt5YI2Vitamin D3 receptor/0.447
3w6hAZMCarbonic anhydrase 14.2.1.10.447
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.447
4c717RD3-oxoacyl-ACP synthase/0.447
4djaFAD(6-4) photolyase/0.447
4e8wIHAD-beta-D-heptose 7-phosphate kinase/0.447
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.447
4f6w0SSCyclin-dependent kinase 82.7.11.220.447
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.447
4ihl1F514-3-3 protein zeta/delta/0.447
4jazSTLPeroxisome proliferator-activated receptor gamma/0.447
4nmdFDABifunctional protein PutA/0.447
4stdBFSScytalone dehydratase4.2.1.940.447
5fltVJJCarbonic anhydrase 24.2.1.10.447
1ez0NAPNADP-dependent fatty aldehyde dehydrogenase1.2.1.40.446
1g45FSBCarbonic anhydrase 24.2.1.10.446
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.446
1ipeNDPTropinone reductase 21.1.1.2360.446
1k0lFADp-hydroxybenzoate hydroxylase/0.446
1n1eNDEGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.80.446
1r58AO5Methionine aminopeptidase 2/0.446
1r5gAO1Methionine aminopeptidase 2/0.446
1w4zNAPPutative ketoacyl reductase1.3.10.446
1xe65FPPlasmepsin-23.4.23.390.446
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.446
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.446
2mm3CHOGastrotropin/0.446
2o7oDXTTetracycline repressor protein class D/0.446
2uxoTACHTH-type transcriptional regulator TtgR/0.446
2xdaJPS3-dehydroquinate dehydratase4.2.1.100.446
2xf3J01Uncharacterized protein/0.446
2xy93ESAngiotensin-converting enzyme3.2.10.446
2xytTC9Soluble acetylcholine receptor/0.446
3af4GCPPantothenate kinase2.7.1.330.446
3ge1ADPGlycerol kinase/0.446
3mknDNBPyrimidine-specific ribonucleoside hydrolase RihB/0.446
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.446
4bfuZVUPantothenate kinase2.7.1.330.446
4dch4DCGlucokinase2.7.1.20.446
4en4ATPPyridoxal kinase2.7.1.350.446
4fki09KCyclin-dependent kinase 22.7.11.220.446
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.446
4g2fC07Ephrin type-A receptor 32.7.10.10.446
4m9aFDAAcyl-CoA dehydrogenase/0.446
4pb25UDNucleoside permease/0.446
4q0a4OAVitamin D3 receptor A/0.446
4qfyDCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.446
4y3zF41Endothiapepsin3.4.23.220.446
6stdMS2Scytalone dehydratase4.2.1.940.446
1bdbNADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase/0.445
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1icpFMN12-oxophytodienoate reductase 11.3.1.420.445
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.445
1oc1ASVIsopenicillin N synthase1.21.3.10.445
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.445
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.445
1x1dSAHC-20 methyltransferase/0.445
2c4jGSOGlutathione S-transferase Mu 22.5.1.180.445
2dvlFADAcyl-CoA dehydrogenase/0.445
2e16SAHDiphthine synthase/0.445
2fhjH4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.445
2fk8SAMHydroxymycolate synthase MmaA42.1.10.445
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.445
2g1s4IGRenin3.4.23.150.445
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.445
2hl0A3SThreonine--tRNA ligase6.1.1.30.445
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.445
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.445
2y3rTRKTamL/0.445
2y3sTIRTamL/0.445
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.445
3f7bAG5Carbonic anhydrase 44.2.1.10.445
3fsjD7KBenzoylformate decarboxylase4.1.1.70.445
3h18PMSEsterase/lipase/0.445
3hatGLY_VAL_ARG_RNGProthrombin3.4.21.50.445
3juhANPCasein kinase II subunit alpha2.7.11.10.445
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3oqkS52Renin3.4.23.150.445
3u8hBHPPhospholipase A2, membrane associated/0.445
4auxXTCTetracycline repressor protein class D/0.445
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.445
4fhf0TTSpore photoproduct lyase/0.445
4lxlPD2Lysine-specific demethylase 4B1.14.110.445
4pkl1GHUncharacterized protein/0.445
4q72FADBifunctional protein PutA/0.445
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.445
5cwa0GAAnthranilate synthase component 14.1.3.270.445
5dcyNAPIridoid synthase1.3.1.990.445
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.444
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.444
1hncGDNGlutathione S-transferase Mu 22.5.1.180.444
1jf0CZHObelin/0.444
1jioDEB6-deoxyerythronolide B hydroxylase/0.444
1mx0ANPType 2 DNA topoisomerase 6 subunit B/0.444
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.444
1x1cSAHC-20 methyltransferase/0.444
2ev9NAPShikimate dehydrogenase (NADP(+))/0.444
2i4qUA4Renin3.4.23.150.444
2jamJ60Calcium/calmodulin-dependent protein kinase type 1G2.7.11.170.444
2jfhLK1UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.444
2jn3JN3Fatty acid-binding protein, liver/0.444
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
2r0cFADPutative FAD-monooxygenase/0.444
2vprTDCTetracycline repressor protein class H/0.444
2vwqNAPGlucose 1-dehydrogenase/0.444
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.444
3aosJH2Hemolymph juvenile hormone binding protein/0.444
3ed1GA3Gibberellin receptor GID1/0.444
3eq6BCOAcyl-coenzyme A synthetase ACSM2A, mitochondrial6.2.1.20.444
3f1kNAPUncharacterized oxidoreductase YciK10.444
3hx4ANPCalmodulin-domain protein kinase 1/0.444
3jpuTY4Transcriptional activator protein LasR/0.444
3jzfJZKBiotin carboxylase6.3.4.140.444
3p62FMNPentaerythritol tetranitrate reductase/0.444
3pe2E1BCasein kinase II subunit alpha2.7.11.10.444
3phiNDPShikimate dehydrogenase (NADP(+))/0.444
3uk6ADPRuvB-like 23.6.4.120.444
3zeiAWHO-acetylserine sulfhydrylase/0.444
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.444
4a86H35Major pollen allergen Bet v 1-A/0.444
4b3aTACTetracycline repressor protein class D/0.444
4bfxZVXPantothenate kinase2.7.1.330.444
4eqkMGTPolymerase basic protein 2/0.444
4h0dZZ7Metallo-beta-lactamase type 2/0.444
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.444
4rupH97Vitamin D3 receptor A/0.444
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.444
8catNDPCatalase1.11.1.60.444
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.443
1hfqMOTDihydrofolate reductase1.5.1.30.443
1jpaANPEphrin type-B receptor 22.7.10.10.443
1mbtFADUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.443
1p8dCO1Oxysterols receptor LXR-beta/0.443
1pq944BOxysterols receptor LXR-beta/0.443
1qjfACSIsopenicillin N synthase1.21.3.10.443
1rk3VDXVitamin D3 receptor/0.443
1rpwDIDHTH-type transcriptional regulator QacR/0.443
1uyuCAMCamphor 5-monooxygenase1.14.15.10.443
1w6hTITPlasmepsin-23.4.23.390.443
2a9y26AAdenosine kinase2.7.1.200.443
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.443
2bvs2CEProthrombin3.4.21.50.443
2qtrNXXProbable nicotinate-nucleotide adenylyltransferase/0.443
2x6o2TCTetracycline repressor protein class D/0.443
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
2yylFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.443
2zb8IMNProstaglandin reductase 21.3.1.480.443
3bgxMEFThymidylate synthase/0.443
3bk2U5PRibonuclease J/0.443
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.443
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.443
3fr28CAFatty acid-binding protein, adipocyte/0.443
3fwfCAMCamphor 5-monooxygenase1.14.15.10.443
3mqgACOLipopolysaccharides biosynthesis acetyltransferase/0.443
3rgzBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.443
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.443
3stv3HOMethylketone synthase I/0.443
3vyfVYFRenin3.4.23.150.443
3zc3NAPFerredoxin--NADP reductase1.18.1.20.443
3zkuHCVIsopenicillin N synthase1.21.3.10.443
4a6nFADTetX family tetracycline inactivation enzyme/0.443
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.443
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.443
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.443
4i4b1CV3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.443
4jq4IMNAldo-keto reductase family 1 member C2/0.443
4ktkKTKCytochrome P450/0.443
4ktoFADPutative isovaleryl-CoA dehydrogenase protein/0.443
4l6gCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.443
4paoGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.443
4yaf2AMNADPH--cytochrome P450 reductase/0.443
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.442
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
1el4CTZObelin/0.442
1h63FMNPentaerythritol tetranitrate reductase/0.442
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.442
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1orkATCTetracycline repressor protein class D/0.442
1t2cNAIL-lactate dehydrogenase1.1.1.270.442
1t4u81AProthrombin3.4.21.50.442
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.442
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
2cf8ESHProthrombin3.4.21.50.442
2ft9CHDFatty acid-binding protein 2, liver/0.442
2hcdBIVVitamin D3 receptor A/0.442
2ipjFFAAldo-keto reductase family 1 member C2/0.442
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.442
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.442
2q59240Peroxisome proliferator-activated receptor gamma/0.442
2uuvFADAlkyldihydroxyacetonephosphate synthase2.5.1.260.442
2xviFADPutative flavin-containing monooxygenase/0.442
2xyuQ9GEphrin type-A receptor 42.7.10.10.442
3bnkFMNFlavoredoxin/0.442
3br2DEQHTH-type transcriptional regulator QacR/0.442
3cgoJNOMitogen-activated protein kinase 102.7.11.240.442
3fhyATPPyridoxal kinase2.7.1.350.442
3g0cRUFDipeptidyl peptidase 4/0.442
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.442
3gncQQQGlutaryl-CoA dehydrogenase/0.442
3k6l2BBPeptide deformylase3.5.1.880.442
3nguADPNucleoside diphosphate kinase/0.442
3pd4A3GThreonine--tRNA ligase6.1.1.30.442
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.442
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.442
3qfcNAPNADPH--cytochrome P450 reductase/0.442
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
3w0yDS4Vitamin D3 receptor/0.442
4a95NHWGlycylpeptide N-tetradecanoyltransferase/0.442
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4eb5PLPCysteine desulfurase IscS 2/0.442
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
4l2yXXKPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.442
4oqyNDP(S)-imine reductase/0.442
4xguADPPutative pachytene checkpoint protein 2/0.442
5jjsSAHGenome polyprotein/0.442
3vw7VPXProteinase-activated receptor 1/0.442
1bl6SB6Mitogen-activated protein kinase 14/0.441
1cbqRE9Cellular retinoic acid-binding protein 2/0.441
1dhiMTXDihydrofolate reductase1.5.1.30.441
1fndA2PFerredoxin--NADP reductase, chloroplastic1.18.1.20.441
1g6oADPCag alpha/0.441
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1gs3EQUSteroid Delta-isomerase5.3.3.10.441
1j49NADD-lactate dehydrogenase1.1.1.280.441
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.441
1p0pBCHCholinesterase3.1.1.80.441
1skmSAHModification methylase HhaI2.1.1.370.441
1tkaN3TTransketolase 12.2.1.10.441
1toiHCIAspartate aminotransferase2.6.1.10.441
1xe55FEPlasmepsin-23.4.23.390.441
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
1ypkCCRProthrombin3.4.21.50.441
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.441
2bf4NAPNADPH--cytochrome P450 reductase/0.441
2d8aNADL-threonine 3-dehydrogenase/0.441
2e20B4PPropionate kinase/0.441
2h23SAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.441
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.441
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.441
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.441
2ydbNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
2zl9VDAVitamin D3 receptor/0.441
3b9lAZZSerum albumin/0.441
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.441
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3fvlBHKCarboxypeptidase A13.4.17.10.441
3g8eIS1Nicotinamide phosphoribosyltransferase2.4.2.120.441
3gdsVAL_TYR_TYR_PHESerine endoprotease DegS3.4.21.1070.441
3ii43IIDihydrolipoyl dehydrogenase1.8.1.40.441
3jziJZLBiotin carboxylase6.3.4.140.441
3nr4PYVAbscisic acid receptor PYL2/0.441
3nz2ACOHexapeptide-repeat containing-acetyltransferase/0.441
3ogwIMNLactoperoxidase1.11.1.70.441
3vtcTK3Vitamin D3 receptor/0.441
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.441
4brgGNPEctonucleoside triphosphate diphosphohydrolase I/0.441
4g090VDHistidinol dehydrogenase/0.441
4g7gVFVLanosterol 14-alpha-demethylase/0.441
4h6kFMNNADPH dehydrogenase 11.6.99.10.441
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.441
4nhyPD2Prolyl 3-hydroxylase OGFOD11.14.110.441
4rvgTYDD-mycarose 3-C-methyltransferase/0.441
4rvnCOAPhenylacetate-coenzyme A ligase/0.441
5ej6TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.441
5fkmTDCTetracycline repressor protein class D/0.441
1g6kNADGlucose 1-dehydrogenase1.1.1.470.440
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1mxfMTXPutative pteridine reductase 2/0.440
1mzs6693-oxoacyl-[acyl-carrier-protein] synthase 3/0.440
1n1dC2GGlycerol-3-phosphate cytidylyltransferase2.7.7.390.440
1q6t600Tyrosine-protein phosphatase non-receptor type 13.1.3.480.440
1stdBFSScytalone dehydratase4.2.1.940.440
1y0s331Peroxisome proliferator-activated receptor delta/0.440
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.440
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.440
2c29NAPDihydroflavonol 4-reductase/0.440
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.440
2dw4FADLysine-specific histone demethylase 1A10.440
2g1y5IGRenin3.4.23.150.440
2npxNADNADH peroxidase1.11.1.10.440
2pb6SAHDiphthine synthase/0.440
2qfvNAPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.440
2z9dFMNFMN-dependent NADH-azoreductase/0.440
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.440
3dagFEG5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.440
3e6yCW114-3-3-like protein C/0.440
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.440
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.440
3imeBZ2Pantothenate synthetase6.3.2.10.440
3iocA5DPantothenate synthetase6.3.2.10.440
3khuUPGUDP-glucose 6-dehydrogenase1.1.1.220.440
3m9vTYDFAD-dependent oxidoreductase/0.440
3mddFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.440
3nxuRITCytochrome P450 3A4/0.440
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.440
3p6nDSOCamphor 5-monooxygenase1.14.15.10.440
3p74FMNPentaerythritol tetranitrate reductase/0.440
3p84FMNPentaerythritol tetranitrate reductase/0.440
3rr3FLRProstaglandin G/H synthase 21.14.99.10.440
3ukrCKHActin-related protein 3/0.440
3ukrCKHActin-related protein 2/0.440
4ac0MIYTetracycline repressor protein class B from transposon Tn10/0.440
4ap1FADSteroid monooxygenase/0.440
4b1rITCTetracycline repressor protein class D/0.440
4b2gV1NUncharacterized protein/0.440
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.440
4ejmNAPPutative zinc-binding dehydrogenase/0.440
4ekg0QJHistone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.440
4em9TCEPeroxisome proliferator-activated receptor gamma/0.440
4f700STCyclin-dependent kinase 82.7.11.220.440
4fweFADLysine-specific histone demethylase 1B10.440
4ia3BIVVitamin D3 receptor A/0.440
4jlj1NMDeoxycytidine kinase2.7.1.740.440
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.440
4jx1CAMCamphor 5-monooxygenase1.14.15.10.440
4kqrVPPPeptidoglycan D,D-transpeptidase FtsI/0.440
4wctFADFructosyl amine:oxygen oxidoreductase/0.440
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.440
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.440