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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3i0rRT3Gag-Pol polyprotein2.7.7.49

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3i0rRT3Gag-Pol polyprotein2.7.7.491.000
3is9AC7Gag-Pol polyprotein2.7.7.490.631
3i0sRT7Gag-Pol polyprotein2.7.7.490.605
3dleGFAGag-Pol polyprotein2.7.7.490.603
1rt2TNKGag-Pol polyprotein2.7.7.490.600
3ffi3OBGag-Pol polyprotein2.7.7.490.597
1tvrTB9Gag-Pol polyprotein2.7.7.490.596
1hpzAAPGag-Pol polyprotein2.7.7.490.595
1c1bGCAGag-Pol polyprotein2.7.7.490.589
1tktH12Gag-Pol polyprotein2.7.7.490.582
1jlaTNKGag-Pol polyprotein2.7.7.490.581
3dmjGWEPol protein/0.576
1tkzH16Gag-Pol polyprotein2.7.7.490.575
3nbpJGZGag-Pol polyprotein2.7.7.490.573
1rtiHEFGag-Pol polyprotein2.7.7.490.565
2ic3HBYGag-Pol polyprotein2.7.7.490.563
2ze2T27Gag-Pol polyprotein2.7.7.490.563
1revTB9Gag-Pol polyprotein2.7.7.490.561
1eetBFUGag-Pol polyprotein2.7.7.490.559
3di6PDZGag-Pol polyprotein2.7.7.490.559
1ep4S11Gag-Pol polyprotein2.7.7.490.557
1hquHBYGag-Pol polyprotein2.7.7.490.555
4i7fNVEGag-Pol polyprotein2.7.7.490.554
2rkiTT1Gag-Pol polyprotein2.7.7.490.553
1rt5UC2Gag-Pol polyprotein2.7.7.490.551
1s9eADBGag-Pol polyprotein2.7.7.490.551
4kko1REGag-Pol polyprotein2.7.7.490.550
3dokGWJPol protein/0.547
1tkxGWBGag-Pol polyprotein2.7.7.490.546
1tl1H18Gag-Pol polyprotein2.7.7.490.546
2ban357Gag-Pol polyprotein2.7.7.490.545
3lamKRPGag-Pol polyprotein2.7.7.490.544
1s1wUC1Gag-Pol polyprotein2.7.7.490.543
3m8qDJZGag-Pol polyprotein2.7.7.490.542
4i2pG73Gag-Pol polyprotein2.7.7.490.542
1vruAAPGag-Pol polyprotein2.7.7.490.541
3t1a5MAGag-Pol polyprotein2.7.7.490.538
4ko0JLJGag-Pol polyprotein2.7.7.490.538
1s1vTNKGag-Pol polyprotein2.7.7.490.536
2vg7NNIGag-Pol polyprotein2.7.7.490.536
4id5T27Gag-Pol polyprotein2.7.7.490.534
3lakKR1Gag-Pol polyprotein2.7.7.490.533
1c1c612Gag-Pol polyprotein2.7.7.490.531
1hniAAAGag-Pol polyprotein2.7.7.490.530
1hnvTBOGag-Pol polyprotein2.7.7.490.528
1ikwEFZGag-Pol polyprotein2.7.7.490.527
1klmSPPGag-Pol polyprotein2.7.7.490.527
2zd1T27Gag-Pol polyprotein2.7.7.490.526
1ikxPNUGag-Pol polyprotein2.7.7.490.523
4g1qT27Gag-Pol polyprotein2.7.7.490.523
2opqHBQGag-Pol polyprotein2.7.7.490.520
3dolGWIPol protein/0.520
1rt4UC1Gag-Pol polyprotein2.7.7.490.519
5cyqT27Gag-Pol polyprotein2.7.7.490.519
3lanKBTGag-Pol polyprotein2.7.7.490.518
1fk9EFZGag-Pol polyprotein2.7.7.490.517
1rt1MKCGag-Pol polyprotein2.7.7.490.516
1s6qTPBGag-Pol polyprotein2.7.7.490.513
2rf2MRXGag-Pol polyprotein2.7.7.490.512
3drpR8EGag-Pol polyprotein2.7.7.490.512
1jlgUC1Gag-Pol polyprotein2.7.7.490.511
3m8p65BGag-Pol polyprotein2.7.7.490.511
1tl3H20Gag-Pol polyprotein2.7.7.490.509
3drrR8EGag-Pol polyprotein2.7.7.490.509
3e01PZ2Gag-Pol polyprotein2.7.7.490.509
3t195MAGag-Pol polyprotein2.7.7.490.508
3dlgGWEGag-Pol polyprotein2.7.7.490.506
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.506
4rw4494Gag-Pol polyprotein2.7.7.490.506
1ikyMSDGag-Pol polyprotein2.7.7.490.505
2zjwREFCasein kinase II subunit alpha2.7.11.10.505
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.504
4i2q1BTGag-Pol polyprotein2.7.7.490.504
3megT27Gag-Pol polyprotein2.7.7.490.500
2opsHBQGag-Pol polyprotein2.7.7.490.499
3be9P04Casein kinase II subunit alpha2.7.11.10.498
4ig3T27Gag-Pol polyprotein2.7.7.490.498
2be2R22Gag-Pol polyprotein2.7.7.490.496
1jlqSBNGag-Pol polyprotein2.7.7.490.494
3lalKRVGag-Pol polyprotein2.7.7.490.494
3med65BGag-Pol polyprotein2.7.7.490.494
2pvnP63Casein kinase II subunit alpha2.7.11.10.493
3mec65BGag-Pol polyprotein2.7.7.490.493
2vg5NNCGag-Pol polyprotein2.7.7.490.492
3dyaPZLGag-Pol polyprotein2.7.7.490.492
4jqeANPCasein kinase II subunit alpha2.7.11.10.492
2hnzPC0Gag-Pol polyprotein2.7.7.490.490
4ifvT27Gag-Pol polyprotein2.7.7.490.488
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.487
4ia2BIVVitamin D3 receptor A/0.485
1cx2S58Prostaglandin G/H synthase 21.14.99.10.484
1s1tUC1Gag-Pol polyprotein2.7.7.490.484
2q59240Peroxisome proliferator-activated receptor gamma/0.484
5a27MYAGlycylpeptide N-tetradecanoyltransferase/0.484
1aq1STUCyclin-dependent kinase 22.7.11.220.483
2hndNVPGag-Pol polyprotein2.7.7.490.483
3r9dX6BCyclin-dependent kinase 22.7.11.220.483
3tamM06Gag-Pol polyprotein2.7.7.490.483
4anmWULCasein kinase II subunit alpha2.7.11.10.483
2b5j3ACGag-Pol polyprotein2.7.7.490.482
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.481
4b12NHWGlycylpeptide N-tetradecanoyltransferase/0.480
2p4yC03Peroxisome proliferator-activated receptor gamma/0.479
4grb0XGCasein kinase II subunit alpha2.7.11.10.479
2oppHBQGag-Pol polyprotein2.7.7.490.478
2vu3LZECyclin-dependent kinase 22.7.11.220.478
2w98P1ZProstaglandin reductase 21.3.1.480.478
3meeT27Gag-Pol polyprotein2.7.7.490.478
3qqkX02Cyclin-dependent kinase 22.7.11.220.477
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.477
5cvfATPCasein kinase II subunit alpha2.7.11.10.477
2duv371Cyclin-dependent kinase 22.7.11.220.475
3bgrT27Gag-Pol polyprotein2.7.7.490.475
3s1h56ZCyclin-dependent kinase 22.7.11.220.475
2ittAEEEpidermal growth factor receptor2.7.10.10.474
1ndeMONEstrogen receptor beta/0.472
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.472
3qtzX42Cyclin-dependent kinase 22.7.11.220.472
4a32MYAGlycylpeptide N-tetradecanoyltransferase/0.472
4a95NHWGlycylpeptide N-tetradecanoyltransferase/0.472
1di8DTQCyclin-dependent kinase 22.7.11.220.471
1oiuN76Cyclin-dependent kinase 22.7.11.220.471
4dgo0JWCasein kinase II subunit alpha2.7.11.10.471
1gii1PUCyclin-dependent kinase 22.7.11.220.470
1oguST8Cyclin-dependent kinase 22.7.11.220.470
1zeoC01Peroxisome proliferator-activated receptor gamma/0.470
2uzbC75Cyclin-dependent kinase 22.7.11.220.470
4b13NHWGlycylpeptide N-tetradecanoyltransferase/0.470
4b14NHWGlycylpeptide N-tetradecanoyltransferase/0.470
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.470
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.469
3at3ATKCasein kinase II subunit alpha2.7.11.10.469
3u4uLNHCasein kinase II subunit alpha2.7.11.10.469
1oitHDTCyclin-dependent kinase 22.7.11.220.468
2w05FRTCyclin-dependent kinase 22.7.11.220.468
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.468
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
4bcmT7ZCyclin-dependent kinase 22.7.11.220.468
1cqp803Integrin alpha-L/0.467
1ezvSMACytochrome b/0.467
2iw84SPCyclin-dependent kinase 22.7.11.220.467
2nmtNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.467
3ddpRC8Cyclin-dependent kinase 22.7.11.220.467
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.467
4a33MYAGlycylpeptide N-tetradecanoyltransferase/0.467
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.466
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.466
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.466
4b10NHWGlycylpeptide N-tetradecanoyltransferase/0.466
5ag7MYAGlycylpeptide N-tetradecanoyltransferase/0.466
1n4hREANuclear receptor ROR-beta/0.465
1xjdSTUProtein kinase C theta type2.7.11.130.465
2x1nX1NCyclin-dependent kinase 22.7.11.220.465
3h1jSMACytochrome b/0.465
4bchT7ZCyclin-dependent kinase 92.7.11.220.465
4o761M3Bromodomain-containing protein 4/0.465
5k2bZMAAdenosine receptor A2a/0.465
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.464
3t8xT8XT-cell surface glycoprotein CD1b/0.464
4a30MYAGlycylpeptide N-tetradecanoyltransferase/0.464
4c4jX21Dual specificity protein kinase TTK2.7.12.10.464
4wsqKSAAP2-associated protein kinase 12.7.11.10.464
1ysx4EBSerum albumin/0.463
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.463
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
2j14GNIPeroxisome proliferator-activated receptor delta/0.462
4c2xNHWGlycylpeptide N-tetradecanoyltransferase 2/0.462
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4jq8KJ8Epidermal growth factor receptor2.7.10.10.462
1zg32HIIsoflavone 4'-O-methyltransferase/0.461
2b55D31Cyclin-dependent kinase 22.7.11.220.461
2itpAEEEpidermal growth factor receptor2.7.10.10.461
2q5p241Peroxisome proliferator-activated receptor gamma/0.461
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.461
3abaFLICytochrome P450/0.461
3cgfJNFMitogen-activated protein kinase 102.7.11.240.461
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.461
3pe2E1BCasein kinase II subunit alpha2.7.11.10.461
3vjhJ35Peroxisome proliferator-activated receptor gamma/0.461
3vspEK8Peroxisome proliferator-activated receptor gamma/0.461
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.461
4ez50RSCyclin-dependent kinase 62.7.11.220.461
4gub0Y4Casein kinase II subunit alpha2.7.11.10.461
4ubsDIFPentalenic acid synthase1.14.15.110.461
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.460
3gc8B45Mitogen-activated protein kinase 112.7.11.240.460
3livE16Protease/0.460
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
3my5RFZCyclin-dependent kinase 22.7.11.220.460
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.460
4a9mP9MBromodomain-containing protein 2/0.460
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4elb34RDihydrofolate reductase/0.460
5ag6MYAGlycylpeptide N-tetradecanoyltransferase/0.460
5cshATPCasein kinase II subunit alpha2.7.11.10.460
6coxS58Prostaglandin G/H synthase 21.14.99.10.460
1q5dEPBEpothilone C/D epoxidase1.140.459
2gtk208Peroxisome proliferator-activated receptor gamma/0.459
2iw94SPCyclin-dependent kinase 22.7.11.220.459
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.459
3ln1CELProstaglandin G/H synthase 21.14.99.10.459
4cgpMYAGlycylpeptide N-tetradecanoyltransferase/0.459
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.459
1nq7ARLNuclear receptor ROR-beta/0.458
1pkdUCNCyclin-dependent kinase 22.7.11.220.458
2p33J07Mitogen-activated protein kinase 102.7.11.240.458
3juhANPCasein kinase II subunit alpha2.7.11.10.458
3nga3NGCasein kinase II subunit alpha2.7.11.10.458
3rmf20ZCyclin-dependent kinase 22.7.11.220.458
3s2pPMUCyclin-dependent kinase 22.7.11.220.458
3t2yFADSulfide-quinone reductase/0.458
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.458
4a2zMYAGlycylpeptide N-tetradecanoyltransferase/0.458
4a4vYFDPeroxisome proliferator-activated receptor gamma/0.458
4c2zMYAGlycylpeptide N-tetradecanoyltransferase 1/0.458
4hee14RPeroxisome proliferator-activated receptor gamma/0.458
4ia7BIVVitamin D3 receptor A/0.458
5uviZMAAdenosine receptor A2a/0.458
1m79MQ1Dihydrofolate reductase1.5.1.30.457
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.457
2izsBRQCasein kinase I isoform gamma-32.7.11.10.457
2xynVX6Abelson tyrosine-protein kinase 22.7.10.20.457
2yneNHWGlycylpeptide N-tetradecanoyltransferase/0.457
3c6tM14Gag-Pol polyprotein2.7.7.490.457
3pqbVGPPutative oxidoreductase/0.457
3rni21ZCyclin-dependent kinase 22.7.11.220.457
4fkv61KCyclin-dependent kinase 22.7.11.220.457
4k2xFADPolyketide oxygenase/hydroxylase/0.457
1m2pHNACasein kinase II subunit alpha2.7.11.10.456
2c7xNRBCytochrome P450 monooxygenase PikC/0.456
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.456
2yekEAMBromodomain-containing protein 2/0.456
3at4CCKCasein kinase II subunit alpha2.7.11.10.456
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.456
3lfnA27Cyclin-dependent kinase 22.7.11.220.456
3zuyTCHTransporter/0.456
4iui1GQEstrogen receptor/0.456
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.456
4rupH97Vitamin D3 receptor A/0.456
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.456
5itzLOCTubulin beta-2B chain/0.456
1e9hINRCyclin-dependent kinase 22.7.11.220.455
1oi9N20Cyclin-dependent kinase 22.7.11.220.455
2fvdLIACyclin-dependent kinase 22.7.11.220.455
2r64740Cyclin-dependent kinase 22.7.11.220.455
2vv9IM9Cyclin-dependent kinase 22.7.11.220.455
2w17I19Cyclin-dependent kinase 22.7.11.220.455
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.455
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.455
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4tvbNADHomospermidine synthase2.5.1.440.455
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.455
1kb9SMACytochrome b/0.454
1oiyN41Cyclin-dependent kinase 22.7.11.220.454
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.454
1sozVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.454
2bheBRYCyclin-dependent kinase 22.7.11.220.454
2hw2RFPRifampin ADP-ribosyl transferase/0.454
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.454
2wleCOAPolysialic acid O-acetyltransferase/0.454
3qtuX44Cyclin-dependent kinase 22.7.11.220.454
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.454
4ejh0QACytochrome P450 2A131.14.14.10.454
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4hgt15GCasein kinase I isoform delta2.7.11.10.454
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.454
5br4NADLactaldehyde reductase1.1.1.770.454
1h1s4SPCyclin-dependent kinase 22.7.11.220.453
1l2jETCEstrogen receptor beta/0.453
1xdiFADNAD(P)H dehydrogenase (quinone)/0.453
1xuoLA1Integrin alpha-L/0.453
1y0s331Peroxisome proliferator-activated receptor delta/0.453
1yc2NADNAD-dependent protein deacylase 2/0.453
3cxhSMACytochrome b/0.453
3eljGS7Mitogen-activated protein kinase 82.7.11.240.453
3frqERYErythromycin resistance repressor protein/0.453
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.453
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.453
3r83Z14Cyclin-dependent kinase 22.7.11.220.453
3rak03ZCyclin-dependent kinase 22.7.11.220.453
3rkb12ZCyclin-dependent kinase 22.7.11.220.453
3sw719KCyclin-dependent kinase 22.7.11.220.453
3zcw4A2Kinesin-like protein KIF11/0.453
4bcpT3CCyclin-dependent kinase 22.7.11.220.453
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4ia1BIVVitamin D3 receptor A/0.453
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
5iua6DXAdenosine receptor A2a/0.453
4z9g1Q5Corticotropin-releasing factor receptor 1/0.453
1fvv107Cyclin-dependent kinase 22.7.11.220.452
1rdt570Peroxisome proliferator-activated receptor gamma/0.452
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.452
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.452
3begANPSRSF protein kinase 12.7.11.10.452
3bfb9ODPheromone-binding protein ASP1/0.452
3ctj320Hepatocyte growth factor receptor2.7.10.10.452
3cwkREACellular retinoic acid-binding protein 2/0.452
3kpkFADSulfide-quinone reductase/0.452
3lltANPProtein serine/threonine kinase-1/0.452
3nynSGVG protein-coupled receptor kinase 62.7.11.160.452
3rpv26ZCyclin-dependent kinase 22.7.11.220.452
3tubFPUTyrosine-protein kinase SYK2.7.10.20.452
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.452
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
4eor4SPCyclin-dependent kinase 22.7.11.220.452
4hgs15GCasein kinase I isoform gamma-32.7.11.10.452
4q5hANPProtein kinase OspG2.70.452
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.452
1hvyD16Thymidylate synthase2.1.1.450.451
2hamC33Vitamin D3 receptor/0.451
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.451
3q92XNBKetohexokinase/0.451
3r8pZ46Cyclin-dependent kinase 22.7.11.220.451
4aguD15Cyclin-dependent kinase-like 1/0.451
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4bcnT9NCyclin-dependent kinase 22.7.11.220.451
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
5av2KMPDeath-associated protein kinase 12.7.11.10.451
1fkoEFZGag-Pol polyprotein2.7.7.490.450
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.450
3d74NBBPheromone-binding protein ASP1/0.450
3dl9V2HVitamin D 25-hydroxylase/0.450
3ezvEZVCyclin-dependent kinase 22.7.11.220.450
3opdHIEHeat shock protein 83/0.450
3qzgX67Cyclin-dependent kinase 22.7.11.220.450
3vt5YI2Vitamin D3 receptor/0.450
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.450
4eon1ROCyclin-dependent kinase 22.7.11.220.450
4iarERM5-hydroxytryptamine receptor 1B/0.450
4o71CPBBromodomain-containing protein 4/0.450
5cvhADPCasein kinase II subunit alpha2.7.11.10.450
1fmjRTLRetinol dehydratase/0.449
1ke6LS2Cyclin-dependent kinase 22.7.11.220.449
1qvnFRIInterleukin-2/0.449
1zhwHC2Oxysterol-binding protein homolog 4/0.449
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.449
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.449
3dhoB2MStreptogramin A acetyltransferase2.3.10.449
3gbk2PQPeroxisome proliferator-activated receptor gamma/0.449
3h0aD30Peroxisome proliferator-activated receptor gamma/0.449
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.449
3syiFADSulfide-quinone reductase/0.449
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4b7dQLECytochrome P450 monooxygenase PikC/0.449
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
4cfnJYMCyclin-dependent kinase 22.7.11.220.449
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4g1wG1WMitogen-activated protein kinase 82.7.11.240.449
4jr3KJREpidermal growth factor receptor2.7.10.10.449
4nc3ERM5-hydroxytryptamine receptor 2B/0.449
1k74544Peroxisome proliferator-activated receptor gamma/0.448
1ppjANYCytochrome b/0.448
1uyePU9Heat shock protein HSP 90-alpha/0.448
1v1k3FPCyclin-dependent kinase 22.7.11.220.448
2b52D42Cyclin-dependent kinase 22.7.11.220.448
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.448
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.448
2pvlP55Casein kinase II subunit alpha2.7.11.10.448
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.448
2yiuSMACytochrome b/0.448
2zbaZBATrichothecene 3-O-acetyltransferase/0.448
3bfa9ODOdorant binding protein ASP1/0.448
3cgoJNOMitogen-activated protein kinase 102.7.11.240.448
3qlrNDPDihydrofolate reductase1.5.1.30.448
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.448
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.448
3sw418KCyclin-dependent kinase 22.7.11.220.448
3t14FADSulfide-quinone reductase/0.448
3tm5SFGUncharacterized protein/0.448
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.448
4apuA2KProgesterone receptor/0.448
4dgnLU2Casein kinase II subunit alpha2.7.11.10.448
4gmy0X5Tyrosine-protein kinase JAK2/0.448
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.448
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.448
4nb6444Nuclear receptor ROR-gamma/0.448
3pwhZMAAdenosine receptor A2a/0.448
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
1om1IQACasein kinase II subunit alpha2.7.11.10.447
1pmn984Mitogen-activated protein kinase 102.7.11.240.447
1umlFR4Adenosine deaminase3.5.4.40.447
1zhzERGOxysterol-binding protein homolog 4/0.447
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.447
2jf9OHTEstrogen receptor/0.447
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.447
3a60STURibosomal protein S6 kinase beta-12.7.11.10.447
3h0sB38Acetyl-CoA carboxylase/0.447
3irxUDRGag-Pol polyprotein2.7.7.490.447
3le62BZCyclin-dependent kinase 22.7.11.220.447
3lixE17Protease/0.447
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.447
3r7yZ04Cyclin-dependent kinase 22.7.11.220.447
3sp9IL2Peroxisome proliferator-activated receptor delta/0.447
3t2zFADSulfide-quinone reductase/0.447
4acm7YGCyclin-dependent kinase 22.7.11.220.447
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.447
4dscA8SAbscisic acid receptor PYL3/0.447
4enhFVXCholesterol 24-hydroxylase/0.447
4f9mFCMPeroxisome proliferator-activated receptor gamma/0.447
4hfmNAP2-alkenal reductase (NADP(+)-dependent)/0.447
4jvmXDIEstrogen sulfotransferase2.8.2.40.447
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.447
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.447
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.447
5e8ySTUTGF-beta receptor type-22.7.11.300.447
1mp0NADAlcohol dehydrogenase class-31.1.1.10.446
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.446
1sn5T3Transthyretin/0.446
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.446
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.446
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.446
2ijmADPFocal adhesion kinase 12.7.10.20.446
3icrCOACoenzyme A disulfide reductase/0.446
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.446
3oom507Activin receptor type-12.7.11.300.446
3p3e3P3UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.446
3rvg17PTyrosine-protein kinase JAK2/0.446
4b7sQLECytochrome P450 monooxygenase PikC/0.446
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.446
4ogrADNCyclin-dependent kinase 92.7.11.220.446
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.446
4k5y1Q5Corticotropin-releasing factor receptor 1/0.446
1bygSTUTyrosine-protein kinase CSK/0.445
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1h1r6CPCyclin-dependent kinase 22.7.11.220.445
1ie8KH1Vitamin D3 receptor/0.445
1ke9LS5Cyclin-dependent kinase 22.7.11.220.445
2c3qGTXGlutathione S-transferase theta-12.5.1.180.445
2hb8MVDVitamin D3 receptor/0.445
2nnhREACytochrome P450 2C8/0.445
2pvhP19Casein kinase II subunit alpha2.7.11.10.445
2q70DC8Estrogen receptor/0.445
2qa2FADPolyketide oxygenase CabE/0.445
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.445
2y00Y01Beta-1 adrenergic receptor/0.445
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.445
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3sheI85MAP kinase-activated protein kinase 32.7.11.10.445
3vtdTKDVitamin D3 receptor/0.445
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.445
4fz60VGTyrosine-protein kinase SYK2.7.10.20.445
4hvi19STyrosine-protein kinase JAK32.7.10.20.445
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.445
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.445
4qa1B3NHistone deacetylase 83.5.1.980.445
5hs1VORLanosterol 14-alpha demethylase/0.445
1wvxBD4Death-associated protein kinase 12.7.11.10.444
2hcdBIVVitamin D3 receptor A/0.444
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.444
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.444
3axwTIDCasein kinase II subunit alpha2.7.11.10.444
3gcoVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.444
3gxlQIGTGF-beta receptor type-12.7.11.300.444
3qlhT27Gag-Pol polyprotein2.7.7.490.444
3t2kFADSulfide-quinone reductase/0.444
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.444
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.444
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.444
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.444
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.444
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.444
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.444
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.443
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.443
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.443
1qxlFR8Adenosine deaminase3.5.4.40.443
1s19MC9Vitamin D3 receptor/0.443
2om9AJAPeroxisome proliferator-activated receptor gamma/0.443
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.443
2qe4JJ3Estrogen receptor/0.443
3eel53TUncharacterized protein/0.443
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.443
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.443
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
3vrwYS5Vitamin D3 receptor/0.443
3w0c6DSVitamin D3 receptor/0.443
3zewSTUEphrin type-B receptor 42.7.10.10.443
4c4g7RODual specificity protein kinase TTK2.7.12.10.443
4eok4SPCyclin-dependent kinase 22.7.11.220.443
4g1z0VPVitamin D3 receptor A/0.443
4hnf16WCasein kinase I isoform delta2.7.11.10.443
4pd6URINucleoside permease/0.443
5kgpACOPredicted acetyltransferase/0.443
1db1VDXVitamin D3 receptor/0.442
1fm6BRLPeroxisome proliferator-activated receptor gamma/0.442
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1pyePM1Cyclin-dependent kinase 22.7.11.220.442
1xdsDRAAclacinomycin 10-hydroxylase RdmB4.1.10.442
2bxqIMNSerum albumin/0.442
2ewaSB2Mitogen-activated protein kinase 14/0.442
2j0m4STFocal adhesion kinase 12.7.10.20.442
2q8sL92Peroxisome proliferator-activated receptor gamma/0.442
2vagV25Dual specificity protein kinase CLK12.7.12.10.442
2y9qANPMitogen-activated protein kinase 12.7.11.240.442
3bc3OPTCathepsin L13.4.22.150.442
3cs8BRLPeroxisome proliferator-activated receptor gamma/0.442
3g7jGTXGlutathione transferase GST1-4/0.442
3gubGUBDeath-associated protein kinase 12.7.11.10.442
3linE13Protease/0.442
3nbvANPKetohexokinase/0.442
3poz03PEpidermal growth factor receptor2.7.10.10.442
3wv9FEGHmd co-occurring protein HcgE/0.442
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4bcoT6QCyclin-dependent kinase 22.7.11.220.442
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.442
4erwSTUCyclin-dependent kinase 22.7.11.220.442
4fa60TAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.442
4g160VMCasein kinase I isoform gamma-32.7.11.10.442
4hge15VTyrosine-protein kinase JAK2/0.442
4ib4ERM5-hydroxytryptamine receptor 2B/0.442
4inb1F6Gag protein/0.442
4o2z046Mitogen-activated protein kinase/0.442
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.442
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.442
1n83CLRNuclear receptor ROR-alpha/0.441
1oirHDYCyclin-dependent kinase 22.7.11.220.441
1pxpCK8Cyclin-dependent kinase 22.7.11.220.441
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.441
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.441
1rm4NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.441
1txiTX5Vitamin D3 receptor/0.441
1v7aFRCAdenosine deaminase3.5.4.40.441
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.441
1yvj4STTyrosine-protein kinase JAK32.7.10.20.441
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.441
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.441
2ph5NADHomospermidine synthase/0.441
2xytTC9Soluble acetylcholine receptor/0.441
2ydwWSHBromodomain-containing protein 2/0.441
3ds6A17Mitogen-activated protein kinase 14/0.441
3kpzZNEVitamin D3 receptor/0.441
3mb714ICasein kinase II subunit alpha2.7.11.10.441
3nszANPCasein kinase II subunit alpha2.7.11.10.441
3owl19ECasein kinase II subunit alpha2.7.11.10.441
3qruX19Cyclin-dependent kinase 22.7.11.220.441
3ral04ZCyclin-dependent kinase 22.7.11.220.441
3s1dZIRCytokinin dehydrogenase 11.5.99.120.441
3tmz06XCytochrome P450 2B41.14.14.10.441
3ua506XCytochrome P450 2B61.14.130.441
4a9iP9IBromodomain-containing protein 2/0.441
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.441
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.441
4kfp1R7Nicotinamide phosphoribosyltransferase2.4.2.120.441
4kwi1TJReductase homolog/0.441
4xivACPChemotaxis protein CheA2.7.13.30.441
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.441
1adcPADAlcohol dehydrogenase E chain1.1.1.10.440
1eh4IC1Casein kinase I homolog 12.7.11.10.440
1g5sI17Cyclin-dependent kinase 22.7.11.220.440
1kkq471Peroxisome proliferator-activated receptor alpha/0.440
1m2rMNYCasein kinase II subunit alpha2.7.11.10.440
1pd9CO4Dihydrofolate reductase1.5.1.30.440
1sqvUHDCytochrome b/0.440
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.440
1xddAAYIntegrin alpha-L/0.440
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.440
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
2c6hPXICytochrome P450 monooxygenase PikC/0.440
2j7t274Serine/threonine-protein kinase 102.7.11.10.440
2jn3JN3Fatty acid-binding protein, liver/0.440
2vtqLZACyclin-dependent kinase 22.7.11.220.440
2x6dX6DAurora kinase A2.7.11.10.440
3a1l2CCCytochrome P450/0.440
3amyAGICasein kinase II subunit alpha2.7.11.10.440
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.440
3d75NBBPheromone-binding protein ASP1/0.440
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3vt9YI4Vitamin D3 receptor/0.440
3w5rLOAVitamin D3 receptor/0.440
4bbe3O4Tyrosine-protein kinase JAK2/0.440
4c4h7RODual specificity protein kinase TTK2.7.12.10.440
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.440
4fmqANPMitogen-activated protein kinase 12.7.11.240.440
4o0wADNAurora kinase A2.7.11.10.440
4riyADPEpidermal growth factor receptor2.7.10.10.440
4yuqKS1Calmodulin-like domain protein kinase/0.440
5dr6SKEAurora kinase A2.7.11.10.440