sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3i0p | NAD | Malate dehydrogenase, putative |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3i0p | NAD | Malate dehydrogenase, putative | / | 1.000 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.490 | |
| 1z2i | NAD | Putative malate dehydrogenase | / | 0.483 | |
| 1gqt | ACP | Ribokinase | / | 0.461 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.450 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.446 | |
| 1v9n | NDP | Malate dehydrogenase | 1.1.1.37 | 0.445 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.443 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.443 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.443 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.441 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.441 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.440 |