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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3hx4ANPCalmodulin-domain protein kinase 1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3hx4ANPCalmodulin-domain protein kinase 1/1.000
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.476
4iebANPCalmodulin-domain protein kinase 1/0.474
3gu83GUDeath-associated protein kinase 12.7.11.10.452
4aotGW8Serine/threonine-protein kinase 102.7.11.10.446
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.445
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.442
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.441
5cnoANPEpidermal growth factor receptor2.7.10.10.440