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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3hv6R39Mitogen-activated protein kinase 14

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3hv6R39Mitogen-activated protein kinase 14/1.000
3hv71AUMitogen-activated protein kinase 14/0.661
3p7bP7BMitogen-activated protein kinase 14/0.633
1kv2B96Mitogen-activated protein kinase 14/0.612
2yisYISMitogen-activated protein kinase 14/0.604
3uvr06FMitogen-activated protein kinase 14/0.592
3p7cP7CMitogen-activated protein kinase 14/0.591
3lfbZ87Mitogen-activated protein kinase 14/0.587
3p7aP7AMitogen-activated protein kinase 14/0.585
2puuG2GMitogen-activated protein kinase 14/0.569
3gcuR48Mitogen-activated protein kinase 14/0.565
3gi3B10Mitogen-activated protein kinase 14/0.545
3p5kP5KMitogen-activated protein kinase 14/0.544
1kv1BMUMitogen-activated protein kinase 14/0.536
3npcB96Mitogen-activated protein kinase 92.7.11.240.532
3o8uBMUMitogen-activated protein kinase 14/0.529
3p78P78Mitogen-activated protein kinase 14/0.529
3nnxEDDMitogen-activated protein kinase 14/0.528
3gcvSS6Mitogen-activated protein kinase 14/0.523
1w82L10Mitogen-activated protein kinase 14/0.522
3k3jF4CMitogen-activated protein kinase 14/0.520
4eh90OQMitogen-activated protein kinase 14/0.518
1wbvLI3Mitogen-activated protein kinase 14/0.510
3hv4L51Mitogen-activated protein kinase 14/0.508
3nnuEDBMitogen-activated protein kinase 14/0.508
1wbsLI2Mitogen-activated protein kinase 14/0.504
2e2b406Tyrosine-protein kinase ABL12.7.10.20.503
2yiwYIWMitogen-activated protein kinase 14/0.502
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.499
4h1m0YJProtein-tyrosine kinase 2-beta2.7.10.20.494
1wbtWBTMitogen-activated protein kinase 14/0.493
4l8mF46Mitogen-activated protein kinase 14/0.489
3os33OSDual specificity mitogen-activated protein kinase kinase 12.7.12.20.488
4z34ON7Lysophosphatidic acid receptor 1/0.486
3ugc046Tyrosine-protein kinase JAK2/0.484
2cciATPCyclin-dependent kinase 22.7.11.220.482
3e9319BMitogen-activated protein kinase 14/0.482
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
3nnwEDDMitogen-activated protein kinase 14/0.480
3nwxKVSGag-Pol polyprotein3.4.23.160.480
1hosPHPGag-Pol polyprotein/0.479
3vhe42QVascular endothelial growth factor receptor 22.7.10.10.479
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.479
4u0i0LIMast/stem cell growth factor receptor Kit2.7.10.10.479
3gc8B45Mitogen-activated protein kinase 112.7.11.240.478
3nynSGVG protein-coupled receptor kinase 62.7.11.160.478
4g170VNCasein kinase I isoform gamma-32.7.11.10.478
2f3kRO1Protease/0.477
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
3ekqROCGag-Pol polyprotein3.4.23.160.477
3uvqFS8Mitogen-activated protein kinase 14/0.477
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.477
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.476
1ivq0PXGag-Pol polyprotein/0.475
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.475
1k6tXN1Gag-Pol polyprotein3.4.23.160.474
1sguMK1Gag-Pol polyprotein3.4.23.160.474
2v51LABActin, alpha skeletal muscle/0.474
3h0sB38Acetyl-CoA carboxylase/0.474
3s56ROCProtease/0.474
3zokNAD3-dehydroquinate synthase, chloroplastic4.2.3.40.474
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.473
1wbnL09Mitogen-activated protein kinase 14/0.473
3ggxGGXGag-Pol polyprotein/0.473
4nka2K7Fibroblast growth factor receptor 1/0.473
3el4ROCGag-Pol polyprotein3.4.23.160.472
3nwq2NCGag-Pol polyprotein3.4.23.160.472
1w2xRCPAcetyl-CoA carboxylase/0.471
2bpz3INGag-Pol polyprotein3.4.23.160.471
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.471
3dfcANPDeath-associated protein kinase 12.7.11.10.471
3pwrROCGag-Pol polyprotein3.4.23.160.471
4k4p3TLGag-Pol polyprotein/0.471
1nvfADPPentafunctional AROM polypeptide/0.470
2cen4AHProtease/0.470
2hiw7MPTyrosine-protein kinase ABL12.7.10.20.470
2pk5075Protease/0.470
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
3ua506XCytochrome P450 2B61.14.130.470
3v013V0Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.470
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.470
1bai0Q4Gag-Pro polyprotein/0.469
1u3cFADCryptochrome-1/0.469
2bpw1INGag-Pol polyprotein3.4.23.160.469
3anlNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.469
3rgaLSBEpoxide hydrolase LasB5.5.10.469
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.469
4djqM86Pol polyprotein/0.469
5hidB1ESerine/threonine-protein kinase B-raf2.7.11.10.469
1k6cMK1Gag-Pol polyprotein3.4.23.160.468
1ohr1UNV-1 PROTEASE protein/0.468
2btsU32Cyclin-dependent kinase 22.7.11.220.468
2upjU02Gag-Pol polyprotein3.4.23.160.468
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
3el51UNGag-Pol polyprotein/0.468
4dqe017Gag-Pol polyprotein/0.468
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.468
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.468
4hgt15GCasein kinase I isoform delta2.7.11.10.468
1bveDMPGag-Pol polyprotein3.4.23.160.467
1hviA77Protease/0.467
2b9wFADPutative aminooxidase/0.467
2qhcAB1Protease/0.467
2qnqQN3Gag-Pol polyprotein3.4.23.160.467
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.467
3t113T1Gag-Pol polyprotein3.4.23.160.467
4j55031Gag-Pol polyprotein3.4.23.160.467
2bpy3INGag-Pol polyprotein3.4.23.160.466
3sls77DDual specificity mitogen-activated protein kinase kinase 12.7.12.20.466
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.466
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.466
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.466
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.466
1difA85Gag-Pol polyprotein/0.465
1fvt106Cyclin-dependent kinase 22.7.11.220.465
1ida0POGag-Pol polyprotein3.4.23.470.465
1wbmBLLPol protein/0.465
2izrBRKCasein kinase I isoform gamma-32.7.11.10.465
2nnpROCProtease/0.465
2p3c3TLProtease/0.465
2yaaATPDeath-associated protein kinase 2/0.465
3dxjNE6DNA-directed RNA polymerase subunit beta/0.465
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.465
3ekt017Gag-Pol polyprotein3.4.23.160.465
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.465
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.465
1b6kPI5Gag-Pol polyprotein3.4.23.160.464
1k6pXN3Gag-Pol polyprotein3.4.23.160.464
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
2qak1UNGag-Pol polyprotein3.4.23.160.464
2y9qANPMitogen-activated protein kinase 12.7.11.240.464
3d83GK6Mitogen-activated protein kinase 14/0.464
3em6017Gag-Pol polyprotein3.4.23.160.464
3k4vROCGag-Pol polyprotein3.4.23.160.464
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.464
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.464
2ba9FADPutative aminooxidase/0.463
2qnnQN1Gag-Pol polyprotein3.4.23.160.463
3el9DR7Gag-Pol polyprotein3.4.23.160.463
3nxe2NCProtease/0.463
3vf7031Gag-Pol polyprotein3.4.23.160.463
4jx1CAHCamphor 5-monooxygenase1.14.15.10.463
1t3r017Gag-Pol polyprotein3.4.23.160.462
2fdd385Pol protein/0.462
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
2om9AJAPeroxisome proliferator-activated receptor gamma/0.462
2qd7065Gag-Pol polyprotein3.4.23.160.462
2r3jSCJCyclin-dependent kinase 22.7.11.220.462
3r28XA0Cyclin-dependent kinase 22.7.11.220.462
4j5j478Gag-Pol polyprotein3.4.23.160.462
1ckpPVBCyclin-dependent kinase 22.7.11.220.461
1dw60Q4Gag-Pol polyprotein3.4.23.160.461
1h1r6CPCyclin-dependent kinase 22.7.11.220.461
1t7kBH0Gag-Pol polyprotein3.4.23.160.461
2fxdDR7Pol polyprotein/0.461
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.461
3okfNAD3-dehydroquinate synthase4.2.3.40.461
3ufnROCGag-Pol polyprotein/0.461
3uwlFOZThymidylate synthase/0.461
4jx1CAMCamphor 5-monooxygenase1.14.15.10.461
1hxwRITGag-Pol polyprotein/0.460
1yt9OISGag-Pol polyprotein/0.460
2aidTHKGag-Pol polyprotein3.4.23.160.460
2k62ITLFatty acid-binding protein, liver/0.460
2p55MRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.460
2q59240Peroxisome proliferator-activated receptor gamma/0.460
2qd6065Gag-Pol polyprotein3.4.23.160.460
2qd8065Gag-Pol polyprotein3.4.23.160.460
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
3d1xROCGag-Pol polyprotein3.4.23.160.460
3dcrKVSProtease/0.460
3wzeBAXVascular endothelial growth factor receptor 22.7.10.10.460
3zcw4A2Kinesin-like protein KIF11/0.460
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.460
4z9rNADOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.460
5br4NADLactaldehyde reductase1.1.1.770.460
1d4yTPVGag-Pol polyprotein3.4.23.160.459
1ijjLARActin, alpha skeletal muscle/0.459
3meeT27Gag-Pol polyprotein2.7.7.490.459
3zewSTUEphrin type-B receptor 42.7.10.10.459
3qakUKAAdenosine receptor A2a/0.459
1atnATPActin, alpha skeletal muscle/0.458
1hvsA77Gag-Pol polyprotein/0.458
1pjkANPCasein kinase II subunit alpha2.7.11.10.458
1s9jBBMDual specificity mitogen-activated protein kinase kinase 12.7.12.20.458
2rkfAB1Pol protein/0.458
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.458
3p79P79Mitogen-activated protein kinase 14/0.458
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.458
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
4dqb017Gag-Pol polyprotein/0.458
4ubsDIFPentalenic acid synthase1.14.15.110.458
5k2bZMAAdenosine receptor A2a/0.458
1d4lPI9Gag-Pol polyprotein3.4.23.160.457
1h1s4SPCyclin-dependent kinase 22.7.11.220.457
1nr5NADPentafunctional AROM polypeptide/0.457
2fde385Gag-Pol polyprotein3.4.23.160.457
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.457
2r38G4GGag-Pol polyprotein3.4.23.160.457
2r43G3GGag-Pol polyprotein3.4.23.160.457
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
3gggNADPrephenate dehydrogenase/0.457
3jvwDMPGag-Pol polyprotein3.4.23.160.457
3lffZ83Mitogen-activated protein kinase 14/0.457
3nu3478Gag-Pol polyprotein3.4.23.160.457
3qihNI7Gag-Pol polyprotein3.4.23.160.457
3tvuB37Acetyl-CoA carboxylase/0.457
4b1vLABActin, alpha skeletal muscle/0.457
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.457
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.457
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.457
4z35ON9Lysophosphatidic acid receptor 1/0.457
1bvgDMPGag-Pol polyprotein3.4.23.160.456
1fff0Q4Gag-Pol polyprotein3.4.23.160.456
1hk1T44Serum albumin/0.456
1mesDMPGag-Pol polyprotein3.4.23.160.456
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.456
2bqvA1AProtease/0.456
2f8g017Gag-Pol polyprotein3.4.23.160.456
2idw017Protease/0.456
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
3v04V04Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.456
4eym0RXMitogen-activated protein kinase 132.7.11.240.456
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.456
4o761M3Bromodomain-containing protein 4/0.456
4rvj478Protease/0.456
5av3KMPDeath-associated protein kinase 12.7.11.10.456
1rl8RITGag-Pol polyprotein3.4.23.160.455
1xp6AIUEstrogen receptor/0.455
2avm2NCGag-Pol polyprotein3.4.23.160.455
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.455
2znnS44Peroxisome proliferator-activated receptor alpha/0.455
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.455
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.455
3qp0NI8Gag-Pol polyprotein3.4.23.160.455
3s85LK0Gag-Pol polyprotein/0.455
3sa323XProtease/0.455
3zptM8YGag-Pol polyprotein3.4.23.160.455
3uzaT4GAdenosine receptor A2a/0.455
1ee0CAA2-pyrone synthase/0.454
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.454
1rdwLARActin, alpha skeletal muscle/0.454
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.454
1u3dFADCryptochrome-1/0.454
2a4fAAUV-1 protease/0.454
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.454
3aidARQGag-Pol polyprotein3.4.23.160.454
3anmNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.454
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.454
3hp552PMitogen-activated protein kinase 14/0.454
3hzc2NCProtease/0.454
3mlbLJZProbable nicotinate-nucleotide adenylyltransferase/0.454
3ndtROCGag-Pol polyprotein3.4.23.160.454
3rpr25ZCyclin-dependent kinase 22.7.11.220.454
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.454
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.454
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.454
4luxQJ8Nitric oxide synthase, brain1.14.13.390.454
1a8g2Z4Gag-Pol polyprotein3.4.23.160.453
1pkdUCNCyclin-dependent kinase 22.7.11.220.453
1qbrXV6Gag-Pol polyprotein3.4.23.160.453
1z1hHBBGag-Pol polyprotein3.4.23.160.453
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.453
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.453
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.453
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.453
3cyxROCGag-Pol polyprotein3.4.23.160.453
3ekuATPActin-5C/0.453
3n7uNADFormate dehydrogenase, chloroplastic/mitochondrial/0.453
3s0o50ZCyclin-dependent kinase 22.7.11.220.453
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.453
4an35Y0Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.453
4c8b0LIReceptor-interacting serine/threonine-protein kinase 22.7.11.10.453
4djoMK5Pol polyprotein/0.453
4eok4SPCyclin-dependent kinase 22.7.11.220.453
4nc3ERM5-hydroxytryptamine receptor 2B/0.453
5dhhDGWNociceptin receptor/0.453
1b6mPI6Gag-Pol polyprotein3.4.23.160.452
1fgc2NCGag-Pol polyprotein3.4.23.160.452
1hshMK1Gag-Pol polyprotein/0.452
1mrxK57Gag-Pol polyprotein3.4.23.160.452
1ndeMONEstrogen receptor beta/0.452
1zyjBI5Mitogen-activated protein kinase 14/0.452
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.452
2q3kMUWGag-Pol polyprotein/0.452
2xyfG40Gag-Pol polyprotein/0.452
2y02Y01Beta-1 adrenergic receptor/0.452
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.452
3d8vUD1Bifunctional protein GlmU/0.452
3em4DR7Gag-Pol polyprotein3.4.23.160.452
3n62XFJNitric oxide synthase, brain1.14.13.390.452
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.452
3qruX19Cyclin-dependent kinase 22.7.11.220.452
3qw2NADMyo-inositol-1-phosphate synthase (Ino1)/0.452
4aa0AA0Mitogen-activated protein kinase 14/0.452
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
4cnjFADL-amino acid oxidase/0.452
4i22IREEpidermal growth factor receptor2.7.10.10.452
4ye3G04Gag-Pol polyprotein3.4.23.160.452
1yinCM3Estrogen receptor/0.451
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.451
2b00GCHPhospholipase A2, major isoenzyme3.1.1.40.451
2bpv1INGag-Pol polyprotein3.4.23.160.451
2fxeDR7Gag-Pol polyprotein3.4.23.160.451
2pv7NADT-protein1.3.1.120.451
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.451
2xyeCXGGag-Pol polyprotein/0.451
3bgcLJHGag-Pol polyprotein3.4.23.160.451
3bqr4RBDeath-associated protein kinase 3/0.451
3d1yROCGag-Pol polyprotein3.4.23.160.451
3dqrJI2Nitric oxide synthase, brain1.14.13.390.451
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.451
3ogqAB1Pol polyprotein/0.451
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
3pp1IZGDual specificity mitogen-activated protein kinase kinase 12.7.12.20.451
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.451
4h3qANPMitogen-activated protein kinase 12.7.11.240.451
4j99ACPFibroblast growth factor receptor 2/0.451
4k5d1Q6Nitric oxide synthase, brain1.14.13.390.451
4pl4ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.451
4wbbADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
1ec3MS3Gag-Pol polyprotein3.4.23.160.450
1hpoUNIGag-Pol polyprotein3.4.23.160.450
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
2qi6MZ8Gag-Pol polyprotein/0.450
3megT27Gag-Pol polyprotein2.7.7.490.450
3qtrX36Cyclin-dependent kinase 22.7.11.220.450
3r9dX6BCyclin-dependent kinase 22.7.11.220.450
3rusADPChaperonin/0.450
4asdBAXVascular endothelial growth factor receptor 22.7.10.10.450
4fc00T2Serine/threonine-protein kinase B-raf2.7.11.10.450
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.450
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.450
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.450
4nk92K5Fibroblast growth factor receptor 1/0.450
5auvAGIDeath-associated protein kinase 12.7.11.10.450
5dr9SKEAurora kinase A2.7.11.10.450
5k2dZMAAdenosine receptor A2a/0.450
4uhrNGIAdenosine receptor A2a/0.450
1fg62NCGag-Pol polyprotein3.4.23.160.449
1gih1PUCyclin-dependent kinase 22.7.11.220.449
1hvkA79Gag-Pol polyprotein/0.449
1iiq0ZRGag-Pol polyprotein3.4.23.160.449
1kxpATPActin, alpha skeletal muscle/0.449
1nvaADPPentafunctional AROM polypeptide/0.449
1p4mFMNRiboflavin kinase2.7.1.260.449
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.449
1wbk568Pol protein/0.449
2fleAIProtease/0.449
2hog710Serine/threonine-protein kinase Chk12.7.11.10.449
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.449
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.449
3cs9NILTyrosine-protein kinase ABL12.7.10.20.449
3ctj320Hepatocyte growth factor receptor2.7.10.10.449
3el1DR7Gag-Pol polyprotein3.4.23.160.449
3fnlSHALactoperoxidase/0.449
3g7jGTXGlutathione transferase GST1-4/0.449
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.449
4btjATPTau-tubulin kinase 12.7.11.10.449
4c4h7RODual specificity protein kinase TTK2.7.12.10.449
4ctaATPCinA-like protein/0.449
4dqh017Gag-Pol polyprotein/0.449
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4j98ACPFibroblast growth factor receptor 2/0.449
4ocvANPAminoglycoside phosphotransferase/0.449
4uuxAPRCinA-like protein/0.449
4y8wSTRSteroid 21-hydroxylase/0.449
5j3wFMNSensory box protein/0.449
5k2cZMAAdenosine receptor A2a/0.449
1ec2BEJGag-Pol polyprotein3.4.23.160.448
1kzkJE2Gag-Pol polyprotein3.4.23.160.448
1qbu846Gag-Pol polyprotein3.4.23.160.448
1vijBAYGag-Pol polyprotein/0.448
1w5vBE3Gag-Pol polyprotein3.4.23.160.448
1xl2189Gag-Pol polyprotein3.4.23.160.448
1zgyBRLPeroxisome proliferator-activated receptor gamma/0.448
2a1eIPFGag-Pol polyprotein3.4.23.160.448
2aoe0Q4Gag-Pol polyprotein3.4.23.160.448
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.448
2cem2AHPol protein/0.448
2iw84SPCyclin-dependent kinase 22.7.11.220.448
2j0m4STFocal adhesion kinase 12.7.10.20.448
2nmyROCProtease/0.448
2nnhREACytochrome P450 2C8/0.448
3ekwDR7Gag-Pol polyprotein3.4.23.160.448
3nnz59WNitric oxide synthase, brain1.14.13.390.448
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.448
3vfa031Gag-Pol polyprotein3.4.23.160.448
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.448
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.448
4at0FADPossible succinate dehydrogenase/0.448
4hdbG52Gag-Pol polyprotein3.4.23.160.448
4hdfG52Gag-Pol polyprotein3.4.23.160.448
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.448
5upjUINGag-Pol polyprotein/0.448
1daz0Q4Gag-Pol polyprotein3.4.23.160.447
1nveNADPentafunctional AROM polypeptide/0.447
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.447
1sh9RITGag-Pol polyprotein3.4.23.160.447
1xdiFADNAD(P)H dehydrogenase (quinone)/0.447
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.447
2uy0HV1Gag-Pol polyprotein3.4.23.160.447
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.447
3nieANPMitogen-activated protein kinase/0.447
3r8pZ46Cyclin-dependent kinase 22.7.11.220.447
4a84DXCMajor pollen allergen Bet v 1-A/0.447
4fkj11KCyclin-dependent kinase 22.7.11.220.447
4k5gQ13Nitric oxide synthase, brain1.14.13.390.447
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.447
4qgiROCGag-Pol polyprotein3.4.23.160.447
1hvjA78Gag-Pol polyprotein/0.446
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
1vyzN5BCyclin-dependent kinase 22.7.11.220.446
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.446
2y03Y01Beta-1 adrenergic receptor/0.446
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.446
3ggaGGWGag-Pol polyprotein/0.446
3lzu017Gag-Pol polyprotein3.4.23.160.446
3rkb12ZCyclin-dependent kinase 22.7.11.220.446
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.446
4aseAV9Vascular endothelial growth factor receptor 22.7.10.10.446
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.446
4cx3HW8Nitric oxide synthase, brain1.14.13.390.446
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.446
4y93746Tyrosine-protein kinase/0.446
5iubCLRAdenosine receptor A2a/0.446
1c6x3INProtease/0.445
1hiiC20Gag-Pol polyprotein/0.445
1idb0DOGag-Pol polyprotein/0.445
1ivp1ZKGag-Pol polyprotein/0.445
1lriCLRBeta-elicitin cryptogein/0.445
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.445
1rrmAPRLactaldehyde reductase1.1.1.770.445
1sdtMK1Gag-Pol polyprotein3.4.23.160.445
1t02LVA3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.445
2b55D31Cyclin-dependent kinase 22.7.11.220.445
2ca0PXICytochrome P450 monooxygenase PikC/0.445
2cmvNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.445
2d3mCOA5,7-dihydroxy-2-methylchromone synthase2.3.1.2160.445
2pk6O33V-1 protease/0.445
2pwcG3GGag-Pol polyprotein3.4.23.160.445
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.445
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2w05FRTCyclin-dependent kinase 22.7.11.220.445
2y4mGDXUncharacterized protein/0.445
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.445
3dk1G05Gag-Pol polyprotein3.4.23.160.445
3jvy017Gag-Pol polyprotein3.4.23.160.445
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.445
3nc9TR3Ketohexokinase/0.445
3qwjX6ACyclin-dependent kinase 22.7.11.220.445
3sa5A69Protease/0.445
3ucb017Gag-Pol polyprotein/0.445
3vs3VSETyrosine-protein kinase HCK2.7.10.20.445
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.445
4a6bQG8Gag-Pol polyprotein3.4.23.160.445
4anmWULCasein kinase II subunit alpha2.7.11.10.445
4aotGW8Serine/threonine-protein kinase 102.7.11.10.445
4dxd9PCCell division protein FtsZ/0.445
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.445
4h3c0YZDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.445
4hgs15GCasein kinase I isoform gamma-32.7.11.10.445
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.445
4oauADP2-5A-dependent ribonuclease3.1.260.445
1c6zROCProtease/0.444
1cqp803Integrin alpha-L/0.444
1eagA70Candidapepsin-23.4.23.240.444
1gx1CDP2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.444
1k1u0Q4Gag-Pol polyprotein3.4.23.160.444
1k6vXN2Gag-Pol polyprotein3.4.23.160.444
1lf3EH5Plasmepsin-23.4.23.390.444
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.444
1rbmKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.444
1sozVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.444
1sx4ADP60 kDa chaperonin/0.444
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.444
2cej1AHPol protein/0.444
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.444
2r3tG4GGag-Pol polyprotein3.4.23.160.444
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.444
3jw2017Gag-Pol polyprotein3.4.23.160.444
3nyg2NCGag-Pol polyprotein3.4.23.160.444
3sa4F72Protease/0.444
3tl9ROCGag-Pol polyprotein3.4.23.160.444
3zk5Z18Cytochrome P450 monooxygenase PikC/0.444
4aguD15Cyclin-dependent kinase-like 1/0.444
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.444
4j95ACPFibroblast growth factor receptor 2/0.444
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.444
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.444
5uviZMAAdenosine receptor A2a/0.444
1b6lPI4Gag-Pol polyprotein3.4.23.160.443
1ec0BEDGag-Pol polyprotein3.4.23.160.443
1ff02NCGag-Pol polyprotein3.4.23.160.443
1ffi2NCGag-Pol polyprotein3.4.23.160.443
1hvlA76Gag-Pol polyprotein/0.443
1oguST8Cyclin-dependent kinase 22.7.11.220.443
1rfqLARActin, alpha skeletal muscle/0.443
1wvxBD4Death-associated protein kinase 12.7.11.10.443
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.443
1zhwHC2Oxysterol-binding protein homolog 4/0.443
2cduFADNADH oxidase/0.443
2izsBRQCasein kinase I isoform gamma-32.7.11.10.443
2oalFADFlavin-dependent tryptophan halogenase RebH1.14.19.90.443
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.443
3a2oKNJGag-Pol polyprotein3.4.23.160.443
3gu7ADPDeath-associated protein kinase 12.7.11.10.443
3qrmNK7Gag-Pol polyprotein3.4.23.160.443
3w2rW2REpidermal growth factor receptor2.7.10.10.443
4bewCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.443
4eol1ROCyclin-dependent kinase 22.7.11.220.443
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.443
4iebANPCalmodulin-domain protein kinase 1/0.443
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.443
4ki8ADP60 kDa chaperonin/0.443
4pd6URINucleoside permease/0.443
5av2KMPDeath-associated protein kinase 12.7.11.10.443
5jtbZMAAdenosine receptor A2a/0.443
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
1gthFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.442
1i8tFADUDP-galactopyranose mutase5.4.99.90.442
1kp8AGS60 kDa chaperonin/0.442
1sduMK1Gag-Pol polyprotein3.4.23.160.442
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.442
2eauCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.442
2hs1017Protease/0.442
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.442
2i0aMUIProtease/0.442
2q61SF1Peroxisome proliferator-activated receptor gamma/0.442
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.442
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.442
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.442
2y00Y01Beta-1 adrenergic receptor/0.442
2y01Y01Beta-1 adrenergic receptor/0.442
3dl9V2HVitamin D 25-hydroxylase/0.442
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
3el01UNGag-Pol polyprotein3.4.23.160.442
3fgoCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.442
3gubGUBDeath-associated protein kinase 12.7.11.10.442
3icsCOACoenzyme A disulfide reductase/0.442
3ncz3NCRho-associated protein kinase 12.7.11.10.442
3opdHIEHeat shock protein 83/0.442
3orn3ORDual specificity mitogen-activated protein kinase kinase 12.7.12.20.442
3tmz06XCytochrome P450 2B41.14.14.10.442
3upjU03Gag-Pol polyprotein/0.442
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.442
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.442
4nyeADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.442
4uymVOR14-alpha sterol demethylase Cyp51B/0.442
4xumIMNPeroxisome proliferator-activated receptor gamma/0.442
5g3sFDAFlavin-dependent L-tryptophan oxidase VioA/0.442
1a9mU0EGag-Pol polyprotein/0.441
1mduATPActin, alpha skeletal muscle/0.441
1xjdSTUProtein kinase C theta type2.7.11.130.441
2fgiPD1Fibroblast growth factor receptor 1/0.441
2j14GNIPeroxisome proliferator-activated receptor delta/0.441
2nnkROCProtease/0.441
2r5q1UNGag-Pol polyprotein/0.441
2uxzHI1Gag-Pol polyprotein3.4.23.160.441
2zb0GK3Mitogen-activated protein kinase 14/0.441
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
3ekv478Gag-Pol polyprotein3.4.23.160.441
3i2l2NCProtease/0.441
3i7eDJRGag-Pol polyprotein/0.441
3kdcJZPGag-Pol polyprotein3.4.23.160.441
3kq7KQ7Mitogen-activated protein kinase 14/0.441
3qpjN4IGag-Pol polyprotein3.4.23.160.441
3qtqX35Cyclin-dependent kinase 22.7.11.220.441
3s00Z60Cyclin-dependent kinase 22.7.11.220.441
3u4uLNHCasein kinase II subunit alpha2.7.11.10.441
3vewADPnebramycin 5' synthase6.1.2.20.441
3wd7COAAcridone synthase/0.441
3wmxNADNAD dependent epimerase/dehydratase/0.441
3wxyCOAUncharacterized protein/0.441
4bgh3I6Cyclin-dependent kinase 22.7.11.220.441
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.441
4h380YXDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.441
4hw764MMacrophage colony-stimulating factor 1 receptor2.7.10.10.441
4jsfQJ4Nitric oxide synthase, brain1.14.13.390.441
4kb81QNCasein kinase I isoform delta2.7.11.10.441
4lgh0JNProto-oncogene tyrosine-protein kinase Src2.7.10.20.441
4lmnEUIDual specificity mitogen-activated protein kinase kinase 12.7.12.20.441
4o2z046Mitogen-activated protein kinase/0.441
4pl8ATPActin, alpha skeletal muscle/0.441
4s34ANPMitogen-activated protein kinase 12.7.11.240.441
4y6nUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.441
1hwr216Gag-Pol polyprotein3.4.23.160.440
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.440
1me7RVPInosine-5'-monophosphate dehydrogenase/0.440
1ot7CHCBile acid receptor/0.440
1tduCB3Thymidylate synthase/0.440
1w0xOLOCyclin-dependent kinase 22.7.11.220.440
2avvMK1Gag-Pol polyprotein3.4.23.160.440
2b0m201Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.440
2e9cB75Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.440
2qci065Gag-Pol polyprotein3.4.23.160.440
3ddpRC8Cyclin-dependent kinase 22.7.11.220.440
3e7iB2Nitric oxide synthase, inducible1.14.13.390.440
3ekyDR7Gag-Pol polyprotein3.4.23.160.440
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.440
3lfnA27Cyclin-dependent kinase 22.7.11.220.440
3nu4478Gag-Pol polyprotein3.4.23.160.440
3nwyGTPUridylate kinase/0.440
3pnf8BXNitric oxide synthase, brain1.14.13.390.440
3poz03PEpidermal growth factor receptor2.7.10.10.440
3t5iSER_SER_CMT_FARRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.440
3vryB43Tyrosine-protein kinase HCK2.7.10.20.440
3zpuM8BGag-Pol polyprotein3.4.23.160.440
4a4wYFBPeroxisome proliferator-activated receptor gamma/0.440
4bcmT7ZCyclin-dependent kinase 22.7.11.220.440
4becATPType I restriction enzyme EcoR124II R protein3.1.21.30.440
4bgg844Activin receptor type-12.7.11.300.440
4djpM73Pol polyprotein/0.440
4djr0KJPol polyprotein/0.440
4ehv0SJMitogen-activated protein kinase 14/0.440
4f640S8Fibroblast growth factor receptor 1/0.440
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.440
4jboWPHAurora kinase A2.7.11.10.440
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.440
4o7uTHFThymidylate synthase/0.440
4pkhADPActin, alpha skeletal muscle/0.440
4r20AERCytochrome P450 family 17 polypeptide 2/0.440