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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3hmm855TGF-beta receptor type-12.7.11.30

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3hmm855TGF-beta receptor type-12.7.11.301.000
3gxlQIGTGF-beta receptor type-12.7.11.300.753
1vjy460TGF-beta receptor type-12.7.11.300.671
2wotZZGTGF-beta receptor type-12.7.11.300.557
5e8wSTUTGF-beta receptor type-12.7.11.300.552
1eh4IC1Casein kinase I homolog 12.7.11.10.551
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.547
5e8ySTUTGF-beta receptor type-22.7.11.300.536
1rw8580TGF-beta receptor type-12.7.11.300.533
4dymIYZActivin receptor type-12.7.11.300.521
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.520
1u4dDBQActivated CDC42 kinase 1/0.519
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.518
1bygSTUTyrosine-protein kinase CSK/0.517
3l8p0CEAngiopoietin-1 receptor2.7.10.10.513
1u54ACPActivated CDC42 kinase 1/0.511
5cnoANPEpidermal growth factor receptor2.7.10.10.511
1aq1STUCyclin-dependent kinase 22.7.11.220.509
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.508
3zewSTUEphrin type-B receptor 42.7.10.10.506
4bgg844Activin receptor type-12.7.11.300.506
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.505
3gubGUBDeath-associated protein kinase 12.7.11.10.504
3ttjJBIMitogen-activated protein kinase 102.7.11.240.504
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.503
4k33ACPFibroblast growth factor receptor 32.7.10.10.503
1g5sI17Cyclin-dependent kinase 22.7.11.220.502
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.502
3kvxFMYMitogen-activated protein kinase 102.7.11.240.499
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.498
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.498
3mtfA3FActivin receptor type-12.7.11.300.498
4e4m0NHTyrosine-protein kinase JAK2/0.498
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.497
4hvi19STyrosine-protein kinase JAK32.7.10.20.496
4jqeANPCasein kinase II subunit alpha2.7.11.10.496
4lfiGNPCasein kinase II subunit alpha2.7.11.10.496
4aqc88ATyrosine-protein kinase JAK2/0.495
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.493
4y95746Tyrosine-protein kinase/0.492
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.491
1py5PY1TGF-beta receptor type-12.7.11.300.491
2b53D23Cyclin-dependent kinase 22.7.11.220.491
2uzbC75Cyclin-dependent kinase 22.7.11.220.491
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.491
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.490
3uyt0CKCasein kinase I isoform delta2.7.11.10.490
4kbk1QGCasein kinase I isoform delta2.7.11.10.490
5cnnANPEpidermal growth factor receptor2.7.10.10.490
4gk3L87Ephrin type-A receptor 32.7.10.10.489
3eljGS7Mitogen-activated protein kinase 82.7.11.240.488
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.488
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.487
4btjADPTau-tubulin kinase 12.7.11.10.486
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.486
2p33J07Mitogen-activated protein kinase 102.7.11.240.485
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.485
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.485
1oirHDYCyclin-dependent kinase 22.7.11.220.484
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.484
4anmWULCasein kinase II subunit alpha2.7.11.10.484
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.484
4jia1K3Tyrosine-protein kinase JAK2/0.484
4eor4SPCyclin-dependent kinase 22.7.11.220.483
1pmn984Mitogen-activated protein kinase 102.7.11.240.482
3oom507Activin receptor type-12.7.11.300.482
3r83Z14Cyclin-dependent kinase 22.7.11.220.482
3ttiKBIMitogen-activated protein kinase 102.7.11.240.482
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.482
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.482
4iwd1JCHepatocyte growth factor receptor2.7.10.10.482
5e92ANPTGF-beta receptor type-22.7.11.300.482
4btjATPTau-tubulin kinase 12.7.11.10.481
4ji91M3Tyrosine-protein kinase JAK2/0.481
2pvnP63Casein kinase II subunit alpha2.7.11.10.480
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.480
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.480
3be9P04Casein kinase II subunit alpha2.7.11.10.479
3k5uPFQAurora kinase A2.7.11.10.479
3le62BZCyclin-dependent kinase 22.7.11.220.479
3sheI85MAP kinase-activated protein kinase 32.7.11.10.479
3w33W19Epidermal growth factor receptor2.7.10.10.479
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.479
4qnyANPMitogen activated protein kinase, putative/0.479
1ir3ANPInsulin receptor2.7.10.10.478
2w17I19Cyclin-dependent kinase 22.7.11.220.478
2xngA0HAurora kinase A2.7.11.10.478
3oriAGSSerine/threonine protein kinase/0.478
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.478
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.478
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.478
4c02TAKActivin receptor type-12.7.11.300.478
4y93746Tyrosine-protein kinase/0.478
1h1s4SPCyclin-dependent kinase 22.7.11.220.477
2c6lDT4Cyclin-dependent kinase 22.7.11.220.477
2yn8STUEphrin type-B receptor 42.7.10.10.477
3lfqA28Cyclin-dependent kinase 22.7.11.220.477
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.477
3w32W32Epidermal growth factor receptor2.7.10.10.477
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.477
4fkv61KCyclin-dependent kinase 22.7.11.220.477
1y91CT9Cyclin-dependent kinase 22.7.11.220.476
2pvhP19Casein kinase II subunit alpha2.7.11.10.476
2x1nX1NCyclin-dependent kinase 22.7.11.220.476
4ewhT77Activated CDC42 kinase 1/0.476
4j95ACPFibroblast growth factor receptor 2/0.476
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.475
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.475
1w8cN69Cyclin-dependent kinase 22.7.11.220.475
1xkkFMMEpidermal growth factor receptor2.7.10.10.475
2pwlACPFibroblast growth factor receptor 2/0.475
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.474
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.474
2wouZZFTGF-beta receptor type-12.7.11.300.474
3gu83GUDeath-associated protein kinase 12.7.11.10.474
3r8vZ62Cyclin-dependent kinase 22.7.11.220.474
3vt8YI3Vitamin D3 receptor/0.474
4f650S9Fibroblast growth factor receptor 1/0.474
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.474
1gih1PUCyclin-dependent kinase 22.7.11.220.473
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.473
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.473
1xjdSTUProtein kinase C theta type2.7.11.130.473
2w06FRVCyclin-dependent kinase 22.7.11.220.473
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.473
3vs3VSETyrosine-protein kinase HCK2.7.10.20.473
3w2sW2REpidermal growth factor receptor2.7.10.10.473
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.473
4m69ANPReceptor-interacting serine/threonine-protein kinase 32.7.11.10.473
3a60STURibosomal protein S6 kinase beta-12.7.11.10.472
3lpbNVBTyrosine-protein kinase JAK2/0.472
3zmmF9JTyrosine-protein kinase JAK2/0.472
4hge15VTyrosine-protein kinase JAK2/0.472
2b7aIZATyrosine-protein kinase JAK2/0.471
2vttLZDCyclin-dependent kinase 22.7.11.220.471
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.471
3iok1P6Tyrosine-protein kinase JAK2/0.471
3rni21ZCyclin-dependent kinase 22.7.11.220.471
4lopSB4Mitogen-activated protein kinase 14/0.471
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.470
2dwbANPAurora kinase A2.7.11.10.470
2eufLQQCyclin-dependent kinase 62.7.11.220.470
3vt9YI4Vitamin D3 receptor/0.470
3zh8C58Protein kinase C iota type2.7.11.130.470
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.470
4kb81QOCasein kinase I isoform delta2.7.11.10.470
4yuqKS1Calmodulin-like domain protein kinase/0.470
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.469
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.469
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.469
2c5yMTWCyclin-dependent kinase 22.7.11.220.469
2ds11CDCyclin-dependent kinase 22.7.11.220.469
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.469
3oroAGSSerine/threonine protein kinase/0.469
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.469
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.468
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.468
3nynSGVG protein-coupled receptor kinase 62.7.11.160.468
3vt7VDXVitamin D3 receptor/0.468
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.468
4ux9ANPMitogen-activated protein kinase 82.7.11.240.468
5e8xSTUTGF-beta receptor type-12.7.11.300.468
1sguMK1Gag-Pol polyprotein3.4.23.160.467
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.467
3rk708ZCyclin-dependent kinase 22.7.11.220.467
5dnrATPAurora kinase A2.7.11.10.467
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.466
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.466
4fklCK2Cyclin-dependent kinase 22.7.11.220.466
1di8DTQCyclin-dependent kinase 22.7.11.220.465
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.465
2qo9ANPEphrin type-A receptor 32.7.10.10.465
2vv9IM9Cyclin-dependent kinase 22.7.11.220.465
3s1h56ZCyclin-dependent kinase 22.7.11.220.465
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.465
4wkqIREEpidermal growth factor receptor2.7.10.10.465
2vx17X8Ephrin type-B receptor 42.7.10.10.464
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.464
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.464
4hvh19RTyrosine-protein kinase JAK32.7.10.20.464
4j99ACPFibroblast growth factor receptor 2/0.464
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.464
4zseANPEpidermal growth factor receptor2.7.10.10.464
2r64740Cyclin-dependent kinase 22.7.11.220.463
2w1fL0FAurora kinase A2.7.11.10.463
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.463
2xneASHAurora kinase A2.7.11.10.463
3tqhNDPQuinone oxidoreductase/0.463
4jq7KJQEpidermal growth factor receptor2.7.10.10.463
1csnATPCasein kinase I homolog 12.7.11.10.462
1dawANPCasein kinase II subunit alpha2.7.11.10.462
1m2pHNACasein kinase II subunit alpha2.7.11.10.462
1oitHDTCyclin-dependent kinase 22.7.11.220.462
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.462
2j0lANPFocal adhesion kinase 12.7.10.20.462
3cgoJNOMitogen-activated protein kinase 102.7.11.240.462
3rkb12ZCyclin-dependent kinase 22.7.11.220.462
3uzp0CKCasein kinase I isoform delta2.7.11.10.462
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.462
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.462
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.462
2cchATPCyclin-dependent kinase 22.7.11.220.461
2xa4AZ5Tyrosine-protein kinase JAK2/0.461
3a7jADPSerine/threonine-protein kinase 242.7.11.10.461
3clyACPFibroblast growth factor receptor 2/0.461
3s2pPMUCyclin-dependent kinase 22.7.11.220.461
4g2fC07Ephrin type-A receptor 32.7.10.10.461
4hnf16WCasein kinase I isoform delta2.7.11.10.461
4ia2BIVVitamin D3 receptor A/0.461
2w1gL0GAurora kinase A2.7.11.10.460
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.460
3cgfJNFMitogen-activated protein kinase 102.7.11.240.460
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.460
3rak03ZCyclin-dependent kinase 22.7.11.220.460
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.460
4fl2ANPTyrosine-protein kinase SYK2.7.10.20.460
4fob0USALK tyrosine kinase receptor2.7.10.10.460
4hvg19QTyrosine-protein kinase JAK32.7.10.20.460
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.460
4foc0UUALK tyrosine kinase receptor2.7.10.10.459
4hjoAQ4Epidermal growth factor receptor2.7.10.10.459
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.459
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.459
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.459
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
2a4lRRCCyclin-dependent kinase 22.7.11.220.458
2vwz7X6Ephrin type-B receptor 42.7.10.10.458
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.458
3lq5SLQCyclin-dependent kinase 92.7.11.220.458
4c62XWWTyrosine-protein kinase JAK2/0.458
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.458
4i22IREEpidermal growth factor receptor2.7.10.10.458
4nk92K5Fibroblast growth factor receptor 1/0.458
5cvhADPCasein kinase II subunit alpha2.7.11.10.458
5drdATPAurora kinase A2.7.11.10.458
2b52D42Cyclin-dependent kinase 22.7.11.220.457
2evaADNMitogen-activated protein kinase kinase kinase 72.7.11.250.457
2v7a627Tyrosine-protein kinase ABL12.7.10.20.457
2xrwANPMitogen-activated protein kinase 82.7.11.240.457
3ggfGVDSerine/threonine-protein kinase 26/0.457
3pxkPXKFocal adhesion kinase 12.7.10.20.457
4acm7YGCyclin-dependent kinase 22.7.11.220.457
4eon1ROCyclin-dependent kinase 22.7.11.220.457
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.457
4gk2L66Ephrin type-A receptor 32.7.10.10.457
4gmy0X5Tyrosine-protein kinase JAK2/0.457
4riyADPEpidermal growth factor receptor2.7.10.10.457
1bwsNDPGDP-L-fucose synthase/0.456
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.456
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.456
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.456
2xs0ANPMitogen-activated protein kinase 82.7.11.240.456
3ormAGSSerine/threonine protein kinase/0.456
3rmf20ZCyclin-dependent kinase 22.7.11.220.456
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.456
4fmqANPMitogen-activated protein kinase 12.7.11.240.456
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.456
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1om1IQACasein kinase II subunit alpha2.7.11.10.455
2uzeC95Cyclin-dependent kinase 22.7.11.220.455
2y9qANPMitogen-activated protein kinase 12.7.11.240.455
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.455
3nieANPMitogen-activated protein kinase/0.455
3t8oATPRhodopsin kinase/0.455
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.455
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.455
1lf3EH5Plasmepsin-23.4.23.390.454
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.454
3cukFADD-amino-acid oxidase1.4.3.30.454
3ddpRC8Cyclin-dependent kinase 22.7.11.220.454
3i60E86Mitogen-activated protein kinase 12.7.11.240.454
3r71X86Cyclin-dependent kinase 22.7.11.220.454
3r9oZ71Cyclin-dependent kinase 22.7.11.220.454
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.454
4loqSB4Mitogen-activated protein kinase 14/0.454
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1jnkANPMitogen-activated protein kinase 102.7.11.240.453
1jpaANPEphrin type-B receptor 22.7.10.10.453
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.453
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.453
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.453
4bcoT6QCyclin-dependent kinase 22.7.11.220.453
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.453
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.453
4j97ACPFibroblast growth factor receptor 2/0.453
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.452
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.452
2itzIREEpidermal growth factor receptor2.7.10.10.452
2r3lSCWCyclin-dependent kinase 22.7.11.220.452
3pj8404Cyclin-dependent kinase 22.7.11.220.452
3vvpBNUUncharacterized protein/0.452
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4ek816KCyclin-dependent kinase 22.7.11.220.452
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4jr7GNPCasein kinase II subunit alpha2.7.11.10.452
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.452
5eypLOCTubulin beta chain/0.452
1h1r6CPCyclin-dependent kinase 22.7.11.220.451
1iyzNDPProbable quinone oxidoreductase/0.451
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.451
1m2qMNXCasein kinase II subunit alpha2.7.11.10.451
1yvj4STTyrosine-protein kinase JAK32.7.10.20.451
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.451
2om9AJAPeroxisome proliferator-activated receptor gamma/0.451
3fln3FNMitogen-activated protein kinase 14/0.451
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.451
3poz03PEpidermal growth factor receptor2.7.10.10.451
4jq8KJ8Epidermal growth factor receptor2.7.10.10.451
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.451
4qmpDKISerine/threonine-protein kinase 242.7.11.10.451
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.451
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1rfvADPPyridoxal kinase2.7.1.350.450
2henADPEphrin type-B receptor 22.7.10.10.450
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.450
2izsBRQCasein kinase I isoform gamma-32.7.11.10.450
2w1hL0FCyclin-dependent kinase 22.7.11.220.450
2zdt46CMitogen-activated protein kinase 102.7.11.240.450
3dogNNNCyclin-dependent kinase 22.7.11.220.450
3r7vZ02Cyclin-dependent kinase 22.7.11.220.450
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.450
4f081RSTyrosine-protein kinase JAK2/0.450
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.450
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.449
2c6o4SPCyclin-dependent kinase 22.7.11.220.449
2c6tDT5Cyclin-dependent kinase 22.7.11.220.449
2o0uC0MMitogen-activated protein kinase 102.7.11.240.449
3dds26BGlycogen phosphorylase, liver form2.4.1.10.449
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.449
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4c61LMMTyrosine-protein kinase JAK2/0.449
4erwSTUCyclin-dependent kinase 22.7.11.220.449
4ic7ANPMitogen-activated protein kinase 72.7.11.240.449
4id71G0Activated CDC42 kinase 1/0.449
4lrjANPUncharacterized protein/0.449
4qmlANPSerine/threonine-protein kinase 242.7.11.10.449
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.449
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.448
2excJNKMitogen-activated protein kinase 102.7.11.240.448
2j0m4STFocal adhesion kinase 12.7.10.20.448
3el4ROCGag-Pol polyprotein3.4.23.160.448
3ik6HCZGlutamate receptor 2/0.448
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.448
4dgnLU2Casein kinase II subunit alpha2.7.11.10.448
4ez50RSCyclin-dependent kinase 62.7.11.220.448
5aaaVGHALK tyrosine kinase receptor2.7.10.10.448
5dn3ATPAurora kinase A2.7.11.10.448
1v9aSAHUncharacterized protein/0.447
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.447
2r3jSCJCyclin-dependent kinase 22.7.11.220.447
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.447
3qtzX42Cyclin-dependent kinase 22.7.11.220.447
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4fkr45KCyclin-dependent kinase 22.7.11.220.447
4fod0UVALK tyrosine kinase receptor2.7.10.10.447
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.447
5dt3ATPAurora kinase A2.7.11.10.447
1dayGNPCasein kinase II subunit alpha2.7.11.10.446
1e3eNAIAlcohol dehydrogenase 41.1.1.10.446
1ol7ADPAurora kinase A2.7.11.10.446
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.446
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.446
2itpAEEEpidermal growth factor receptor2.7.10.10.446
2pvlP55Casein kinase II subunit alpha2.7.11.10.446
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.446
3hl7I47Mitogen-activated protein kinase 14/0.446
3il1B5DGlutamate receptor 2/0.446
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.446
3rvg17PTyrosine-protein kinase JAK2/0.446
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.446
3vryB43Tyrosine-protein kinase HCK2.7.10.20.446
4a6cQG9Gag-Pol polyprotein3.4.23.160.446
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.446
4fv4EK7Mitogen-activated protein kinase 12.7.11.240.446
4kba1QMCasein kinase I isoform delta2.7.11.10.446
4nifANPMitogen-activated protein kinase 12.7.11.240.446
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.446
1dhrNADDihydropteridine reductase1.5.1.340.445
1ivq0PXGag-Pol polyprotein/0.445
1nytNAPShikimate dehydrogenase (NADP(+))/0.445
1pxoCK7Cyclin-dependent kinase 22.7.11.220.445
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.445
2izrBRKCasein kinase I isoform gamma-32.7.11.10.445
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.445
2uznC96Cyclin-dependent kinase 22.7.11.220.445
3lfnA27Cyclin-dependent kinase 22.7.11.220.445
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.445
4f9b0SYCell division cycle 7-related protein kinase2.7.11.10.445
4f9c0SXCell division cycle 7-related protein kinase2.7.11.10.445
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.445
4mwhATPCasein kinase II subunit alpha2.7.11.10.445
1p4fDRGDeath-associated protein kinase 12.7.11.10.444
1pmv537Mitogen-activated protein kinase 102.7.11.240.444
1sxjADPReplication factor C subunit 5/0.444
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.444
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.444
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.444
2pvmP29Casein kinase II subunit alpha2.7.11.10.444
2q5g1FAPeroxisome proliferator-activated receptor delta/0.444
2vwy7X5Ephrin type-B receptor 42.7.10.10.444
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.444
3at4CCKCasein kinase II subunit alpha2.7.11.10.444
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.444
3c4zADPRhodopsin kinase/0.444
3sqq99ZCyclin-dependent kinase 22.7.11.220.444
4c4jX21Dual specificity protein kinase TTK2.7.12.10.444
4gub0Y4Casein kinase II subunit alpha2.7.11.10.444
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.444
4o1pANPRibonuclease L/0.444
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
1ebyBEBGag-Pol polyprotein3.4.23.160.443
1gii1PUCyclin-dependent kinase 22.7.11.220.443
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.443
2bqvA1AProtease/0.443
2pmdGNPTranslation initiation factor 2 subunit gamma/0.443
2w05FRTCyclin-dependent kinase 22.7.11.220.443
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.443
2xnbY8LCyclin-dependent kinase 22.7.11.220.443
3eyhIZATyrosine-protein kinase JAK1/0.443
3lltANPProtein serine/threonine kinase-1/0.443
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.443
4btmF8ETau-tubulin kinase 12.7.11.10.443
1nvtNAPShikimate dehydrogenase (NADP(+))/0.442
1oguST8Cyclin-dependent kinase 22.7.11.220.442
2fxdDR7Pol polyprotein/0.442
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.442
2oorNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.442
2x9fX9FEphrin type-B receptor 42.7.10.10.442
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.442
3lmgANPReceptor tyrosine-protein kinase erbB-32.7.10.10.442
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.442
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.442
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.442
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.442
3zonIK1Non-receptor tyrosine-protein kinase TYK22.7.10.20.442
4b0gVEKAurora kinase A2.7.11.10.442
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.442
4g1wG1WMitogen-activated protein kinase 82.7.11.240.442
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1k6tXN1Gag-Pol polyprotein3.4.23.160.441
1ke7LS3Cyclin-dependent kinase 22.7.11.220.441
1w0xOLOCyclin-dependent kinase 22.7.11.220.441
2a0cCK9Cyclin-dependent kinase 22.7.11.220.441
2bfyH1NAurora kinase B-A2.7.11.10.441
2bhhRYUCyclin-dependent kinase 22.7.11.220.441
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.441
2c6kDT2Cyclin-dependent kinase 22.7.11.220.441
2ebaFADPutative glutaryl-CoA dehydrogenase/0.441
2gjlFMNNitronate monooxygenase1.13.12.160.441
2iw94SPCyclin-dependent kinase 22.7.11.220.441
2pvjP44Casein kinase II subunit alpha2.7.11.10.441
2qo7ANPEphrin type-A receptor 32.7.10.10.441
2r5q1UNGag-Pol polyprotein/0.441
2wxvWXVCyclin-dependent kinase 22.7.11.220.441
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.441
3el51UNGag-Pol polyprotein/0.441
3h8bNSYCathepsin L13.4.22.150.441
3nx4NAPPutative oxidoreductase/0.441
3qu0X40Cyclin-dependent kinase 22.7.11.220.441
3r9dX6BCyclin-dependent kinase 22.7.11.220.441
3rk507ZCyclin-dependent kinase 22.7.11.220.441
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.441
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.441
3zep1NXTyrosine-protein kinase JAK32.7.10.20.441
4deeADPAurora kinase A2.7.11.10.441
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.441
4kb81QNCasein kinase I isoform delta2.7.11.10.441
1c6yMK1Protease/0.440
1dhjMTXDihydrofolate reductase1.5.1.30.440
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.440
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.440
1zemNADXylitol dehydrogenase/0.440
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.440
2vtqLZACyclin-dependent kinase 22.7.11.220.440
2vx07X7Ephrin type-B receptor 42.7.10.10.440
2w9hTOPDihydrofolate reductase1.5.1.30.440
2wpa889Cyclin-dependent kinase 22.7.11.220.440
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.440
2xb7GUIALK tyrosine kinase receptor2.7.10.10.440
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.440
3f03FMNPentaerythritol tetranitrate reductase/0.440
3fhyATPPyridoxal kinase2.7.1.350.440
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.440
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.440
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.440
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.440
4pl3ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.440