sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3h3f | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3h3f | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 1.000 | |
| 4l4s | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.567 | |
| 4rls | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.556 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.550 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.530 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.530 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.494 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.482 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.472 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.469 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.468 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.468 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.468 | |
| 1ez4 | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.466 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.461 | |
| 1b8u | NAD | Malate dehydrogenase | / | 0.457 | |
| 2ldb | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.457 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.456 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.456 | |
| 3pqf | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.454 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.454 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.449 | |
| 4ajp | 88N | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.447 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.445 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.443 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 4ajn | 88V | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.440 | |
| 4ajj | 88R | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 |