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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3h2sNDPPutative NADH-flavin reductase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3h2sNDPPutative NADH-flavin reductase/1.000
4rvgTYDD-mycarose 3-C-methyltransferase/0.475
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.472
4a83DXCMajor pollen allergen Bet v 1-A/0.472
4xguADPPutative pachytene checkpoint protein 2/0.460
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.452
1me6IVSPlasmepsin-23.4.23.390.451
4acuQN7Beta-secretase 13.4.23.460.451
4a81DXCMajor pollen allergen Bet v 1-A/0.450
3fr5I4AFatty acid-binding protein, adipocyte/0.449
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.449
4a84DXCMajor pollen allergen Bet v 1-A/0.447
1w6hTITPlasmepsin-23.4.23.390.446
2qjoNADBifunctional NMN adenylyltransferase/Nudix hydrolase2.7.7.10.446
4x28FDAAcyl-CoA dehydrogenase FadE26/0.446
4x28FDAAcyl-CoA dehydrogenase FadE27/0.446
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.445
3lqfNADGalactitol dehydrogenase/0.445
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.444
4bb3KKAIsopenicillin N synthase1.21.3.10.442
5jscFADPutative acyl-CoA dehydrogenase/0.442
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1ma0NADAlcohol dehydrogenase class-31.1.1.10.441
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.440