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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3gtcGTCBeta-lactamase3.5.2.6

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3gtcGTCBeta-lactamase3.5.2.61.000
2pu2DK2Beta-lactamase3.5.2.60.600
2r9w23CBeta-lactamase3.5.2.60.587
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.533
2ea2F77Methionine aminopeptidase 2/0.523
1yw8A75Methionine aminopeptidase 2/0.517
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.501
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.500
2g8yNADHydroxycarboxylate dehydrogenase B/0.499
3af1GDPPantothenate kinase2.7.1.330.497
1zp3FAD5,10-methylenetetrahydrofolate reductase1.5.1.200.496
1xddAAYIntegrin alpha-L/0.494
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.494
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.493
2r59PH0Leukotriene A-4 hydrolase3.3.2.60.493
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.492
4bfxZVXPantothenate kinase2.7.1.330.492
2whqHI6Acetylcholinesterase3.1.1.70.491
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.491
2oapANPType II secretion system protein (GspE-2)/0.487
3c1y2BADNA integrity scanning protein DisA/0.485
5dw50T1Succinyl-CoA:acetate CoA-transferase/0.484
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.483
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.483
3oqkS52Renin3.4.23.150.483
3rdqDTBStreptavidin/0.483
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.483
2ea4F79Methionine aminopeptidase 2/0.482
3q43D66M1 family aminopeptidase3.4.110.482
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.481
4i9n1E5L-lactate dehydrogenase A chain1.1.1.270.481
2fj1CTCTetracycline repressor protein class D/0.480
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.480
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.480
1tilATPAnti-sigma F factor/0.479
2gv8NDPThiol-specific monooxygenase1.14.130.479
4ocvANPAminoglycoside phosphotransferase/0.479
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.478
3qt62P0Mevalonate diphosphate decarboxylase/0.478
3to3ATPPetrobactin biosynthesis protein AsbB/0.478
2gesCOKPantothenate kinase2.7.1.330.477
4eu4COASuccinyl-CoA:acetate CoA-transferase/0.477
2geuCOKPantothenate kinase2.7.1.330.476
2po7CHDFerrochelatase, mitochondrial4.99.1.10.476
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.476
2vuuNAPNitrogen metabolite repression protein nmrA/0.476
4f3gKAIGlutamate receptor 3/0.476
4q0kGA3Phytohormone-binding protein/0.476
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.475
2z4sADPChromosomal replication initiator protein DnaA/0.475
3rykTYDdTDP-4-dehydrorhamnose 3,5-epimerase/0.475
3uk6ADPRuvB-like 23.6.4.120.475
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.475
4m4922YL-lactate dehydrogenase A chain1.1.1.270.475
4xguADPPutative pachytene checkpoint protein 2/0.475
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.474
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.474
1qzyTDEMethionine aminopeptidase 2/0.474
5ah5LSSLeucine--tRNA ligase/0.474
1yw9A84Methionine aminopeptidase 2/0.473
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.473
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.472
2iqgF2IBeta-secretase 13.4.23.460.472
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.472
2zrfDTPProtein RecA/0.472
3fhxPXLPyridoxal kinase2.7.1.350.472
1ppkIVVPenicillopepsin-13.4.23.200.471
2a94AP0L-lactate dehydrogenase1.1.1.270.471
2g247IGRenin3.4.23.150.471
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.471
2rlcCHDCholoylglycine hydrolase3.5.1.240.471
3bk2U5PRibonuclease J/0.471
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.471
4dptAGSMevalonate diphosphate decarboxylase/0.471
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.470
2futH1SHeparin and heparin-sulfate lyase/0.470
2g1n1IGRenin3.4.23.150.470
4dfg0JVGag-Pol polyprotein3.4.23.160.470
4djaFAD(6-4) photolyase/0.470
4dpuAGSMevalonate diphosphate decarboxylase/0.470
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.469
3oqfS51Renin3.4.23.150.469
4lh71X8DNA ligase/0.469
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.468
1vf3GDNGlutathione S-transferase 32.5.1.180.468
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3fr5I4AFatty acid-binding protein, adipocyte/0.468
3h06VBPGlutamate receptor 2/0.468
5kwvANPPantothenate synthetase/0.468
2ikuLIYRenin3.4.23.150.467
3h7rNAPAldo-keto reductase family 4 member C8/0.467
5kgpACOPredicted acetyltransferase/0.467
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.466
2ejzSAHDiphthine synthase/0.466
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.466
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.466
2zs9ADPPantothenate kinase2.7.1.330.466
3h3r14HCollagen type IV alpha-3-binding protein/0.466
3rbaCODPhosphopantetheine adenylyltransferase/0.466
3u9eCOALmo1369 protein/0.466
3zj7C1KStrictosidine-O-beta-D-glucosidase3.2.1.1050.466
4b4w9L9Bifunctional protein FolD/0.466
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.466
4hy6FJ1Heat shock protein HSP 90-alpha/0.466
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.466
2vkeTACTetracycline repressor protein class D/0.465
2zrvFNRIsopentenyl-diphosphate delta-isomerase/0.465
3dv5BAVBeta-secretase 13.4.23.460.465
3otwCOAPhosphopantetheine adenylyltransferase/0.465
3qfaFADThioredoxin reductase 1, cytoplasmic1.8.1.90.465
3uylTYDProbable NDP-rhamnosyltransferase/0.465
4b63NAPL-ornithine N(5)-monooxygenase/0.465
4gv7MEWPoly [ADP-ribose] polymerase 12.4.2.300.465
1tojHCIAspartate aminotransferase2.6.1.10.464
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.464
2w6pOA4Biotin carboxylase6.3.4.140.464
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
3hk1B64Fatty acid-binding protein, adipocyte/0.464
3lq4TDPPyruvate dehydrogenase E1 component1.2.4.10.464
3tqxPLP2-amino-3-ketobutyrate coenzyme A ligase/0.464
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.464
4u0mATPCyclic GMP-AMP synthase/0.464
1i59ANPChemotaxis protein CheA2.7.13.30.463
1k7fIAVTryptophan synthase alpha chain/0.463
1n2hPAJPantothenate synthetase6.3.2.10.463
2lfoGCHFatty acid-binding protein, liver/0.463
3e8xNAPBH1520 protein/0.463
3ojxFMNNADPH--cytochrome P450 reductase/0.463
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.463
4b68FADL-ornithine N(5)-monooxygenase/0.463
4ryvZEAProtein LlR18A/0.463
1gc5ADPADP-dependent glucokinase2.7.1.1470.462
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.462
1r5hAO2Methionine aminopeptidase 2/0.462
2briANPUridylate kinase2.7.4.220.462
2i7nACOPantothenate kinase 12.7.1.330.462
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.462
2wedPP6Penicillopepsin-13.4.23.200.462
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.462
4nesUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.462
1bk0ACVIsopenicillin N synthase1.21.3.10.461
1t2cNAIL-lactate dehydrogenase1.1.1.270.461
2g1r3IGRenin3.4.23.150.461
2p83MR0Beta-secretase 13.4.23.460.461
3hl0NADMaleylacetate reductase/0.461
3p62FMNPentaerythritol tetranitrate reductase/0.461
3rpeFADPutative modulator of drug activity/0.461
3uyk0CXProbable NDP-rhamnosyltransferase/0.461
4kbyC2EStimulator of interferon genes protein/0.461
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.461
1thnADPAnti-sigma F factor/0.460
2qbuSAHPrecorrin-2 methyltransferase/0.460
2z95NDPGDP-mannose 4,6-dehydratase/0.460
2zrxFMNIsopentenyl-diphosphate delta-isomerase/0.460
3eksCY9Actin-5C/0.460
3fsuFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.460
3fzfATPHeat shock cognate 71 kDa protein/0.460
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.460
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.460
4biwANPSensor histidine kinase CpxA/0.460
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.460
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.460
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.460
1h51FMNPentaerythritol tetranitrate reductase/0.459
1zp4FAD5,10-methylenetetrahydrofolate reductase1.5.1.200.459
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.459
2vutNADNitrogen metabolite repression protein nmrA/0.459
2xviFADPutative flavin-containing monooxygenase/0.459
3qlrNDPDihydrofolate reductase1.5.1.30.459
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.459
4bfuZVUPantothenate kinase2.7.1.330.459
4twnB96Ephrin type-A receptor 32.7.10.10.459
1g7vPAI2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.458
2cnsACORibosomal-protein-alanine acetyltransferase/0.458
2uxoTACHTH-type transcriptional regulator TtgR/0.458
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.458
4m9aFDAAcyl-CoA dehydrogenase/0.458
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.458
5czySAMEukaryotic huntingtin interacting protein B/0.458
1qrpHH0Pepsin A-43.4.23.10.457
1s4oGDPGlycolipid 2-alpha-mannosyltransferase/0.457
2i4qUA4Renin3.4.23.150.457
2iviACWIsopenicillin N synthase1.21.3.10.457
3b9xNOSPyrimidine-specific ribonucleoside hydrolase RihB3.2.2.80.457
3dgeADPSensor histidine kinase/0.457
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.457
3t64DU3Deoxyuridine 5'-triphosphate nucleotidohydrolase/0.457
3ufl508Beta-secretase 13.4.23.460.457
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
4gxs0YSGlutamate receptor 2/0.457
5dp2NAPCurF/0.457
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.456
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.456
1zrqFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.456
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.456
2iko7IGRenin3.4.23.150.456
2ob0ACON-alpha-acetyltransferase 50/0.456
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.456
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.456
2zreAGSProtein RecA/0.456
2zs8ADPPantothenate kinase2.7.1.330.456
3arvSAUChitinase A/0.456
3ig6438Urokinase-type plasminogen activator3.4.21.730.456
3nr4PYVAbscisic acid receptor PYL2/0.456
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.456
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.456
4psbGA3Cytokinin-specific binding protein/0.456
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.455
1kqnNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.455
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.455
2hpvFMNFMN-dependent NADH-azoreductase1.70.455
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.455
2wzySQXSoluble acetylcholine receptor/0.455
2y6fM9FIsopenicillin N synthase1.21.3.10.455
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.455
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.455
4rvgTYDD-mycarose 3-C-methyltransferase/0.455
1dxyNADD-2-hydroxyisocaproate dehydrogenase1.1.10.454
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.454
1x1bSAHC-20 methyltransferase/0.454
2ed3SAHDiphthine synthase/0.454
2qtaTDPPyruvate dehydrogenase E1 component1.2.4.10.454
3rvhHQ2Lysine-specific demethylase 4A1.14.110.454
3w6hAZMCarbonic anhydrase 14.2.1.10.454
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.454
4g090VDHistidinol dehydrogenase/0.454
4itxIN5Cystathionine beta-lyase MetC4.4.1.80.454
1lrkUD1UDP-glucose 4-epimerase5.1.3.20.453
1rzuADPGlycogen synthase 12.4.1.210.453
1sdwIYTPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.453
1vyrFMNPentaerythritol tetranitrate reductase/0.453
1z44FMNNADPH dehydrogenase/0.453
2bxqIMNSerum albumin/0.453
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.453
2x90EALAngiotensin-converting enzyme3.4.15.10.453
2xf3J01Uncharacterized protein/0.453
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.453
3b05FNRIsopentenyl-diphosphate delta-isomerase/0.453
3fhxPLPPyridoxal kinase2.7.1.350.453
3h3qH13Collagen type IV alpha-3-binding protein/0.453
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.453
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.453
4i0h1BLBeta-secretase 13.4.23.460.453
4lxk1YTBeta-secretase 13.4.23.460.453
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.453
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.453
4s0vSUVOrexin receptor type 2/0.453
1h50FMNPentaerythritol tetranitrate reductase/0.452
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.452
1jraFADFAD-linked sulfhydryl oxidase ERV21.8.3.20.452
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.452
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.452
1ri1GTGmRNA cap guanine-N7 methyltransferase2.1.1.560.452
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.452
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.452
2j415GPGuanylate kinase/0.452
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.452
4b68NAPL-ornithine N(5)-monooxygenase/0.452
4bftZVTPantothenate kinase2.7.1.330.452
4bfzZVZPantothenate kinase2.7.1.330.452
4s1iPLPPyridoxal kinase, putative/0.452
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.452
1fw0KAIGlutamate receptor 2/0.451
1lb9DNQGlutamate receptor 2/0.451
1m8jNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.451
2qo9ANPEphrin type-A receptor 32.7.10.10.451
2x91LPRAngiotensin-converting enzyme3.4.15.10.451
3h3sH15Collagen type IV alpha-3-binding protein/0.451
3junAJDPhenazine biosynthesis protein A/B/0.451
3ogwIMNLactoperoxidase1.11.1.70.451
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.451
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.451
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.451
4gd40WSLysine-specific demethylase 4A1.14.110.451
4i9h1E4L-lactate dehydrogenase A chain1.1.1.270.451
4j0v1H7Beta-secretase 13.4.23.460.451
4l0qNADAlcohol dehydrogenase class-3/0.451
4rvfTYDD-mycarose 3-C-methyltransferase/0.451
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.451
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.451
4xnw2IDP2Y purinoceptor 1/0.451
1a9cGTPGTP cyclohydrolase 13.5.4.160.450
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.450
1x8lOXRRetinol dehydratase/0.450
1yqzCOACoenzyme A disulfide reductase/0.450
2a4xBLMMitomycin-binding protein/0.450
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.450
2a9z26AAdenosine kinase2.7.1.200.450
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.450
2iyaZIOOleandomycin glycosyltransferase/0.450
2w6cBM4Acetylcholinesterase3.1.1.70.450
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.450
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.450
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
4j1k1HGBeta-secretase 13.4.23.460.450
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.450
4mv1ADPBiotin carboxylase6.3.4.140.450
1l0oADPAnti-sigma F factor/0.449
1ppm0P1Penicillopepsin-13.4.23.200.449
1towCRZFatty acid-binding protein, adipocyte/0.449
2clmF6FTryptophan synthase alpha chain/0.449
2pncCLUPrimary amine oxidase, liver isozyme/0.449
2y3sTIRTamL/0.449
3af0GDPPantothenate kinase2.7.1.330.449
3ai0PNWBeta-glucosidase/0.449
3c36KAIGlutamate receptor ionotropic, kainate 1/0.449
3fp0FP015-O-acetyltransferase/0.449
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.449
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.449
5d4vYGPUncharacterized protein MJ0489/0.449
1cf3FADGlucose oxidase1.1.3.40.448
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.448
1jqdSAHHistamine N-methyltransferase2.1.1.80.448
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.448
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.448
1me7MOAInosine-5'-monophosphate dehydrogenase/0.448
1xe55FEPlasmepsin-23.4.23.390.448
2gjlFMNNitronate monooxygenase1.13.12.160.448
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.448
2iyfERYOleandomycin glycosyltransferase2.4.10.448
2vceU2FUDP-glycosyltransferase 72B1/0.448
3c35KAIGlutamate receptor ionotropic, kainate 1/0.448
3g0yP9A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.448
3h3t16HCollagen type IV alpha-3-binding protein/0.448
4b1e6T6Beta-secretase 13.4.23.460.448
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
4ol0GTPGTP-binding nuclear protein Ran/0.448
4qzuRTLRetinol-binding protein 2/0.448
1obnASVIsopenicillin N synthase1.21.3.10.447
1x1cSAHC-20 methyltransferase/0.447
1z7yAA5Cysteine synthase 12.5.1.470.447
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.447
2a9y26AAdenosine kinase2.7.1.200.447
2c12FADNitroalkane oxidase1.7.3.10.447
2j3qTFLAcetylcholinesterase3.1.1.70.447
2xy93ESAngiotensin-converting enzyme3.2.10.447
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3a3gDLZLumazine protein/0.447
3q9bB3NAcetylpolyamine amidohydrolase/0.447
3qeoLLTDeoxycytidine kinase2.7.1.740.447
3rucNADUDP-N-acetylglucosamine 4-epimerase/0.447
4aoaIK2Beta-phenylalanine transaminase2.6.10.447
4iawLIZNeutrophil gelatinase-associated lipocalin/0.447
4qaiFMNNADPH dehydrogenase/0.447
4tm1FDAKtzI/0.447
5ao1DG3Deoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.447
1b5tFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.446
1digL37C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.446
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.446
1nzfUPGDNA beta-glucosyltransferase/0.446
1t3zCAOFormyl-CoA:oxalate CoA-transferase/0.446
1ve3SAMUncharacterized protein/0.446
1xe65FPPlasmepsin-23.4.23.390.446
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.446
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.446
2xlrFADPutative flavin-containing monooxygenase/0.446
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.446
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3h2sNDPPutative NADH-flavin reductase/0.446
3lpjZ75Beta-secretase 13.4.23.460.446
3lqfNADGalactitol dehydrogenase/0.446
3vyeVYERenin3.4.23.150.446
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.446
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.446
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.446
4ohvANPProtein clpf-1/0.446
4djhJDCKappa-type opioid receptor/0.446
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.445
1cdoNADAlcohol dehydrogenase 11.1.1.10.445
1d3pBT3Prothrombin3.4.21.50.445
1fmlRTLRetinol dehydratase/0.445
1h69ARHNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.445
2flhZEACytokinin-specific binding protein/0.445
2ignFADPyranose 2-oxidase/0.445
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.445
2pj4414Carboxypeptidase B/0.445
2rqfJH3Hemolymph juvenile hormone binding protein/0.445
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.445
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3ruaNADUDP-N-acetylglucosamine 4-epimerase/0.445
3tneRITCandidapepsin-13.4.23.240.445
4a83DXCMajor pollen allergen Bet v 1-A/0.445
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.445
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.445
4ih71ERGenome polyprotein2.7.7.480.445
5c1mCLRMu-type opioid receptor/0.445
1esmCOAPantothenate kinase2.7.1.330.444
1h63FMNPentaerythritol tetranitrate reductase/0.444
1kqcFMNOxygen-insensitive NAD(P)H nitroreductase/0.444
1n2iPAJPantothenate synthetase6.3.2.10.444
1tehNADAlcohol dehydrogenase class-31.1.1.10.444
1ty9FMNPhenazine biosynthesis protein PhzG1.40.444
1w7h3IPMitogen-activated protein kinase 14/0.444
2cekN8TAcetylcholinesterase3.1.1.70.444
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.444
2hm1LIQBeta-secretase 13.4.23.460.444
2jb4A14Isopenicillin N synthase1.21.3.10.444
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.444
2npxNADNADH peroxidase1.11.1.10.444
3rqqBA3ADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.444
4bgbADPPredicted molecular chaperone distantly related to HSP70-fold metalloproteases/0.444
4idgNADPutative UDP-glucose 4-epimerase/0.444
4itmATPTetraacyldisaccharide 4'-kinase/0.444
4to3DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.444
1a8rGTPGTP cyclohydrolase 13.5.4.160.443
1cjkFOKAdenylate cyclase type 2/0.443
1cjkFOKAdenylate cyclase type 5/0.443
1culFOKAdenylate cyclase type 2/0.443
1culFOKAdenylate cyclase type 5/0.443
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.443
1l8qADPChromosomal replication initiator protein DnaA/0.443
1o76CAMCamphor 5-monooxygenase1.14.15.10.443
1s4pGDPGlycolipid 2-alpha-mannosyltransferase/0.443
1toiHCIAspartate aminotransferase2.6.1.10.443
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.443
2g1s4IGRenin3.4.23.150.443
2g21L1BRenin3.4.23.150.443
2g226IGRenin3.4.23.150.443
2wqpWQPPolysialic acid capsule biosynthesis protein SiaC/0.443
3co93MSGenome polyprotein2.7.7.480.443
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
3in6FMNUncharacterized protein/0.443
3junAKDPhenazine biosynthesis protein A/B/0.443
3ns2PYVAbscisic acid receptor PYL2/0.443
4a86H35Major pollen allergen Bet v 1-A/0.443
4y3qF02Endothiapepsin3.4.23.220.443
4y4jLNREndothiapepsin3.4.23.220.443
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.443
1cnfFADNitrate reductase [NADH]1.7.1.10.442
1g1aNADdTDP-glucose 4,6-dehydratase/0.442
1h22E10Acetylcholinesterase3.1.1.70.442
1mewXMPInosine-5'-monophosphate dehydrogenase/0.442
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.442
1x1aSAMC-20 methyltransferase/0.442
1z48FMNNADPH dehydrogenase/0.442
2c20NADUDP-glucose 4-epimerase/0.442
2g1o2IGRenin3.4.23.150.442
2jh0701Prothrombin3.4.21.50.442
2xlpNAPPutative flavin-containing monooxygenase/0.442
2xveFADPutative flavin-containing monooxygenase/0.442
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.442
3apwDP0Alpha-1-acid glycoprotein 2/0.442
3d2rADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.442
3fstFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.442
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
3jziJZLBiotin carboxylase6.3.4.140.442
3k5c0BIBeta-secretase 13.4.23.460.442
3qe2FMNNADPH--cytochrome P450 reductase/0.442
4dbzNDPPutative ketoacyl reductase1.3.10.442
4gsuDWZL,D-transpeptidase 22.3.20.442
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.442
4oztP1AEcdysone receptor, putative/0.442
4tlzFADKtzI/0.442
4y45F91Endothiapepsin3.4.23.220.442
4yau2AMNADPH--cytochrome P450 reductase/0.442
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.442
1d0lBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.441
1fmjRTLRetinol dehydratase/0.441
1jpaANPEphrin type-B receptor 22.7.10.10.441
1nzdUPGDNA beta-glucosyltransferase/0.441
1rp7TZDPyruvate dehydrogenase E1 component1.2.4.10.441
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.441
1tl7FOKAdenylate cyclase type 2/0.441
1tl7FOKAdenylate cyclase type 5/0.441
1xmmM7Gm7GpppX diphosphatase3.6.1.590.441
2b56UTPRNA editing complex protein MP57/0.441
2bu9HFVIsopenicillin N synthase1.21.3.10.441
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.441
2eh5SAHDiphthine synthase/0.441
2emuSAHDiphthine synthase/0.441
2ftoTMPThymidylate synthase/0.441
2ieaTDPPyruvate dehydrogenase E1 component1.2.4.10.441
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.441
2zvcSAHPrecorrin-3 C17-methyltransferase/0.441
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.441
3d4bDZDNAD-dependent protein deacetylase/0.441
3f63GTXGlutathione transferase GST1-4/0.441
3gw9VNILanosterol 14-alpha-demethylase/0.441
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.441
3jzdNADMaleylacetate reductase/0.441
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.441
3koyZ97D-ornithine 4,5-aminomutase subunit beta/0.441
3nmpPYVAbscisic acid receptor PYL2/0.441
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.441
4cmfPXGUncharacterized protein/0.441
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.441
4zj8SUVOrexin receptor type 1/0.441
1dhrNADDihydropteridine reductase1.5.1.340.440
1kqwRTLCellular retinol-binding protein type II/0.440
1o97FADElectron transfer flavoprotein subunit alpha/0.440
1p5rCOAFormyl-CoA:oxalate CoA-transferase/0.440
1r5gAO1Methionine aminopeptidase 2/0.440
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.440
1udaUFGUDP-glucose 4-epimerase5.1.3.20.440
1vsoAT1Glutamate receptor ionotropic, kainate 1/0.440
1w6hTITPlasmepsin-23.4.23.390.440
1w6rGNTAcetylcholinesterase3.1.1.70.440
1wuaAP8Actin, alpha skeletal muscle/0.440
1ygkRRCPyridoxal kinase2.7.1.350.440
2abbFMNPentaerythritol tetranitrate reductase/0.440
2f3rG5PGuanylate kinase2.7.4.80.440
2ft9CHDFatty acid-binding protein 2, liver/0.440
2g1y5IGRenin3.4.23.150.440
2he5NDPAldo-keto reductase family 1 member C211.1.10.440
3bgxTMPThymidylate synthase/0.440
3mauEXTPutative sphingosine-1-phosphate lyase/0.440
3rueNADUDP-N-acetylglucosamine 4-epimerase/0.440
3s2v3HUGlutamate receptor ionotropic, kainate 1/0.440
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.440
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.440
3vydVYDRenin3.4.23.150.440
3w5hFADNADH-cytochrome b5 reductase 31.6.2.20.440
3ziuLSSLeucyl-tRNA synthetase/0.440
4b1rITCTetracycline repressor protein class D/0.440
4bamMM9Prothrombin3.4.21.50.440
4bfsZVSPantothenate kinase2.7.1.330.440
4d89BXDBeta-secretase 13.4.23.460.440
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.440
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.440
4i1iNADMalate dehydrogenase/0.440
4ohwATPProtein clpf-1/0.440
4tx9AMZPhosphoribosyl isomerase A/0.440
4txzG2PCyclic GMP-AMP synthase/0.440
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.440
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
5agaANPDNA polymerase theta/0.440
5d3qGDPDynamin-13.6.5.50.440