Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3gduTYR_ARG_PHESerine endoprotease DegS3.4.21.107

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3gduTYR_ARG_PHESerine endoprotease DegS3.4.21.1071.000
3gdvTYR_GLN_PHESerine endoprotease DegS3.4.21.1070.647
3gcoVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.476
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.447
5bmvVLBTubulin alpha-1B chain/0.443
5bmvVLBTubulin beta chain/0.443
2q5g1FAPeroxisome proliferator-activated receptor delta/0.440
2xlpFADPutative flavin-containing monooxygenase/0.440