sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3g2l | LEW | Glycogen phosphorylase, muscle form | 2.4.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3g2l | LEW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 1.000 | |
| 2qln | F59 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.664 | |
| 4eke | D1I | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.642 | |
| 1k08 | BZD | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.576 | |
| 3ms4 | 21N | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.561 | |
| 3zcs | CAW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.549 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.536 | |
| 2qn3 | F55 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.527 | |
| 2qn7 | HBZ | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.526 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.492 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.492 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.491 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.485 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.483 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.480 | |
| 3g2h | KOT | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.480 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.479 | |
| 5a3b | APR | SIR2 family protein | / | 0.479 | |
| 2qrq | S13 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.478 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.477 | |
| 4qxr | 1YE | Stimulator of interferon genes protein | / | 0.477 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1wng | SAH | Diphthine synthase | / | 0.470 | |
| 3fr8 | NDP | Ketol-acid reductoisomerase, chloroplastic | 1.1.1.86 | 0.470 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.470 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.469 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.469 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.469 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.468 | |
| 4xj4 | 3AT | Cyclic GMP-AMP synthase | / | 0.468 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.467 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.467 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.466 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.466 | |
| 2el0 | SAH | Diphthine synthase | / | 0.465 | |
| 3evb | SAH | Genome polyprotein | 2.1.1.56 | 0.465 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.465 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.465 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.465 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.463 | |
| 4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 3co9 | 3MS | Genome polyprotein | 2.7.7.48 | 0.462 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.462 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.462 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.461 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.461 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.461 | |
| 2dsi | SAH | Diphthine synthase | / | 0.461 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.461 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 4txz | G2P | Cyclic GMP-AMP synthase | / | 0.461 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.461 | |
| 2hut | SAH | Diphthine synthase | / | 0.460 | |
| 4blr | UTP | NTPase P4 | / | 0.460 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.460 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.459 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.459 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.459 | |
| 3l7d | DK5 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.459 | |
| 3s2v | 3HU | Glutamate receptor ionotropic, kainate 1 | / | 0.459 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.459 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.458 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.458 | |
| 3vv8 | B02 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.458 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.457 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.457 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.457 | |
| 3dg8 | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.457 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.456 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.456 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.456 | |
| 2zja | ACP | ATP-dependent DNA helicase Hel308 | / | 0.456 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.456 | |
| 3ing | NDP | Homoserine dehydrogenase related protein | / | 0.456 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 1sgu | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 2cej | 1AH | Pol protein | / | 0.455 | |
| 2hg1 | N5O | Endoplasmin | / | 0.455 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.455 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.455 | |
| 4cki | ADN | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.455 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.454 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.453 | |
| 1kev | NDP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.453 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2bkz | SBC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2y3s | TIR | TamL | / | 0.453 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.453 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.453 | |
| 4im0 | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.453 | |
| 1gve | NAP | Aflatoxin B1 aldehyde reductase member 3 | 1 | 0.452 | |
| 1z0d | GDP | Ras-related protein Rab-5C | / | 0.452 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.452 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.452 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.451 | |
| 2dxx | SAH | Diphthine synthase | / | 0.451 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.451 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.451 | |
| 2os1 | BB2 | Peptide deformylase | / | 0.451 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.451 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.451 | |
| 3kfs | 3TL | Gag-Pol polyprotein | / | 0.451 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.451 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.451 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.450 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.450 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.450 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.450 | |
| 2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.450 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.450 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.450 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.449 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.449 | |
| 3ocp | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.449 | |
| 3ort | AGS | Serine/threonine protein kinase | / | 0.449 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.449 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.449 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.449 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.448 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.448 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.448 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.448 | |
| 3a3g | DLZ | Lumazine protein | / | 0.448 | |
| 3aeb | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.448 | |
| 3r4b | 74T | Gag-Pol polyprotein | / | 0.448 | |
| 3vf3 | 0GS | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3zdi | UGJ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.448 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.448 | |
| 4yjd | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.448 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.448 | |
| 1bdr | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 1jmg | UMP | Thymidylate synthase | / | 0.447 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.447 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.447 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 3t6i | NC9 | Endothiapepsin | 3.4.23.22 | 0.447 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.447 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.447 | |
| 4q1x | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.447 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.447 | |
| 1rp7 | TZD | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.446 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.446 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.446 | |
| 2hs1 | 017 | Protease | / | 0.446 | |
| 3o9i | A61 | Gag-Pol polyprotein | / | 0.446 | |
| 3omu | IBD | Heat shock protein 83 | / | 0.446 | |
| 3zhy | FM6 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.446 | |
| 4dja | FAD | (6-4) photolyase | / | 0.446 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.445 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.445 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.445 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.445 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.445 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.445 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.445 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.445 | |
| 2zkj | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.445 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 3mxd | K53 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3qvs | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.445 | |
| 3qw4 | U5P | Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | / | 0.445 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.445 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.445 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.445 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.445 | |
| 1a94 | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1b5t | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.444 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1mrw | K57 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.444 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.444 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.444 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.444 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.444 | |
| 2pch | SAH | Diphthine synthase | / | 0.444 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.444 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.444 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.444 | |
| 4egh | 0OY | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4u7w | NDP | MxaA | / | 0.444 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.443 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.443 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.443 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.443 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.443 | |
| 3e8n | VRA | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.443 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.443 | |
| 3ge6 | FMN | Nitroreductase | / | 0.443 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.443 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.443 | |
| 3o9d | K19 | Pol polyprotein | / | 0.443 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.443 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4eut | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.443 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.443 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 4kvz | SAH | PtnL protein | / | 0.443 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.443 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 1k2c | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.442 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.442 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.442 | |
| 3o96 | IQO | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.442 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.442 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4cpd | NAD | Alcohol dehydrogenase | / | 0.442 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.442 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.442 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.442 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.442 | |
| 4z0g | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.442 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.441 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.441 | |
| 1t7k | BH0 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.441 | |
| 2dph | NAD | Formaldehyde dismutase | / | 0.441 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.441 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.441 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.441 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.441 | |
| 3vx4 | ATP | Putative ABC transporter, ATP-binding protein ComA | / | 0.441 | |
| 3wbf | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.441 | |
| 4fuj | 1U9 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.441 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.441 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.441 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.441 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.441 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.441 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.440 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.440 | |
| 1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.440 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 2p20 | PRX | Acetyl-coenzyme A synthetase | / | 0.440 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.440 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.440 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.440 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3o9h | K2E | Gag-Pol polyprotein | / | 0.440 | |
| 3tog | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 4el0 | D1K | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.440 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.440 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.440 | |
| 4w6z | 8ID | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.440 | |
| 4xsv | CTP | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.440 |