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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3fzsB96Protein-tyrosine kinase 2-beta2.7.10.2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3fzsB96Protein-tyrosine kinase 2-beta2.7.10.21.000
4h1j0YHProtein-tyrosine kinase 2-beta2.7.10.20.584
3fzt4JZProtein-tyrosine kinase 2-beta2.7.10.20.572
2hog710Serine/threonine-protein kinase Chk12.7.11.10.528
4k9yK9YFocal adhesion kinase 12.7.10.20.517
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.507
4elb34RDihydrofolate reductase/0.507
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.502
2owb626Serine/threonine-protein kinase PLK12.7.11.210.501
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.500
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.499
1ove358Mitogen-activated protein kinase 14/0.498
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.497
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.496
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.494
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.493
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.492
4equG6ISerine/threonine-protein kinase 102.7.11.10.492
3cqeP91Wee1-like protein kinase2.7.10.20.491
3zkpERBErythromycin C-12 hydroxylase1.14.13.1540.490
2c6o4SPCyclin-dependent kinase 22.7.11.220.488
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.487
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.486
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.485
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.485
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.484
2ij7TPFMycocyclosin synthase1.14.21.90.483
3d78NBBPheromone-binding protein ASP1/0.483
1xjdSTUProtein kinase C theta type2.7.11.130.482
4a4l939Serine/threonine-protein kinase PLK12.7.11.210.482
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.482
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.481
2izsBRQCasein kinase I isoform gamma-32.7.11.10.481
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.481
3bqr4RBDeath-associated protein kinase 3/0.481
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.481
1wvxBD4Death-associated protein kinase 12.7.11.10.480
3s2pPMUCyclin-dependent kinase 22.7.11.220.480
3t8oATPRhodopsin kinase/0.480
2etm7PYFocal adhesion kinase 12.7.10.20.479
2j0m4STFocal adhesion kinase 12.7.10.20.479
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.478
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.478
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.477
3fl8RARDihydrofolate reductase/0.477
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.477
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.477
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.477
4ic7ANPMitogen-activated protein kinase 72.7.11.240.477
4jbtASDCytochrome P450 monooxygenase/0.477
1h1s4SPCyclin-dependent kinase 22.7.11.220.476
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.476
3my5RFZCyclin-dependent kinase 22.7.11.220.476
4jlk1NODeoxycytidine kinase2.7.1.740.476
5k2bZMAAdenosine receptor A2a/0.476
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.475
3qtuX44Cyclin-dependent kinase 22.7.11.220.475
4fnyI3KALK tyrosine kinase receptor2.7.10.10.475
1ke6LS2Cyclin-dependent kinase 22.7.11.220.474
3r8lZ30Cyclin-dependent kinase 22.7.11.220.474
3tubFPUTyrosine-protein kinase SYK2.7.10.20.474
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.474
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.473
4bcqTJFCyclin-dependent kinase 22.7.11.220.473
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.473
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.472
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.472
4ib4ERM5-hydroxytryptamine receptor 2B/0.472
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.472
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.471
5uviZMAAdenosine receptor A2a/0.471
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.470
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.470
5k2aZMAAdenosine receptor A2a/0.470
1ke7LS3Cyclin-dependent kinase 22.7.11.220.469
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.469
4bgh3I6Cyclin-dependent kinase 22.7.11.220.469
3rfmCFFAdenosine receptor A2a/0.469
1ie4T44Transthyretin/0.468
3uyt0CKCasein kinase I isoform delta2.7.11.10.468
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.468
1j7uANPAminoglycoside 3'-phosphotransferase2.7.1.950.467
2xb7GUIALK tyrosine kinase receptor2.7.10.10.467
3bi6396Wee1-like protein kinase2.7.10.20.467
4bcmT7ZCyclin-dependent kinase 22.7.11.220.467
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.467
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.467
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.467
1i5aACPChemotaxis protein CheA2.7.13.30.466
1mvsDTMDihydrofolate reductase1.5.1.30.466
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.466
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.466
2p33J07Mitogen-activated protein kinase 102.7.11.240.466
3qu0X40Cyclin-dependent kinase 22.7.11.220.466
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.466
3zsh469Mitogen-activated protein kinase 14/0.466
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.466
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.466
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.466
1g5sI17Cyclin-dependent kinase 22.7.11.220.465
1oguST8Cyclin-dependent kinase 22.7.11.220.465
2in6839Wee1-like protein kinase2.7.10.20.465
2uzoC62Cyclin-dependent kinase 22.7.11.220.465
2w05FRTCyclin-dependent kinase 22.7.11.220.465
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.465
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.465
1ckpPVBCyclin-dependent kinase 22.7.11.220.464
1fm4DXCMajor pollen allergen Bet v 1-L/0.464
1oi9N20Cyclin-dependent kinase 22.7.11.220.464
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.464
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.464
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.464
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.464
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.464
4eevL1XHepatocyte growth factor receptor2.7.10.10.464
1xddAAYIntegrin alpha-L/0.463
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.463
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.463
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.463
2vrx447Aurora kinase B-A2.7.11.10.463
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.463
2yac937Serine/threonine-protein kinase PLK12.7.11.210.463
3iok1P6Tyrosine-protein kinase JAK2/0.463
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.463
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.463
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.463
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
5cvhADPCasein kinase II subunit alpha2.7.11.10.463
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.462
4j6bPLOCytochrome P450 monooxygenase/0.462
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.461
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.461
2excJNKMitogen-activated protein kinase 102.7.11.240.461
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.461
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.461
4at0FADPossible succinate dehydrogenase/0.461
4fv9E71Mitogen-activated protein kinase 12.7.11.240.461
4j6dTESCytochrome P450 monooxygenase/0.461
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.461
4r20AERCytochrome P450 family 17 polypeptide 2/0.461
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.460
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.460
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.460
2fvdLIACyclin-dependent kinase 22.7.11.220.460
2qk8MTXDihydrofolate reductase/0.460
2uxpCLMHTH-type transcriptional regulator TtgR/0.460
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.460
3rkb12ZCyclin-dependent kinase 22.7.11.220.460
3tk3CPZCytochrome P450 2B41.14.14.10.460
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.460
4eiyZMAAdenosine receptor A2a/0.460
4ele31IDihydrofolate reductase/0.460
4g1wG1WMitogen-activated protein kinase 82.7.11.240.460
4gmy0X5Tyrosine-protein kinase JAK2/0.460
4jlj1NMDeoxycytidine kinase2.7.1.740.460
1bygSTUTyrosine-protein kinase CSK/0.459
1pkdUCNCyclin-dependent kinase 22.7.11.220.459
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.459
3bfa9ODOdorant binding protein ASP1/0.459
3iqeF42F420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.459
3mtfA3FActivin receptor type-12.7.11.300.459
3qzhX69Cyclin-dependent kinase 22.7.11.220.459
3r1qX75Cyclin-dependent kinase 22.7.11.220.459
3r9dX6BCyclin-dependent kinase 22.7.11.220.459
4ysjADPCalmodulin-like domain protein kinase/0.459
1i59ADPChemotaxis protein CheA2.7.13.30.458
1v0pPVBCell division control protein 2 homolog2.7.11.220.458
2iw84SPCyclin-dependent kinase 22.7.11.220.458
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.458
3pe2E1BCasein kinase II subunit alpha2.7.11.10.458
4b99R4LMitogen-activated protein kinase 72.7.11.240.458
4fob0USALK tyrosine kinase receptor2.7.10.10.458
4j6cSTRCytochrome P450 monooxygenase/0.458
1ke5LS1Cyclin-dependent kinase 22.7.11.220.457
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.457
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.457
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.457
2iw94SPCyclin-dependent kinase 22.7.11.220.457
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.457
3at4CCKCasein kinase II subunit alpha2.7.11.10.457
3ddpRC8Cyclin-dependent kinase 22.7.11.220.457
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.457
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.457
3jwcEKBDihydrofolate reductase/0.457
3t8xT8XT-cell surface glycoprotein CD1b/0.457
3zk6H1IBcl-2-like protein 1/0.457
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.457
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.457
5auwQUEDeath-associated protein kinase 12.7.11.10.457
5jtbZMAAdenosine receptor A2a/0.457
1di8DTQCyclin-dependent kinase 22.7.11.220.456
1i58ADPChemotaxis protein CheA2.7.13.30.456
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.456
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.456
2hckQUETyrosine-protein kinase HCK2.7.10.20.456
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.456
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.456
3jwm5WBDihydrofolate reductase/0.456
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.456
3r1sX73Cyclin-dependent kinase 22.7.11.220.456
3zsgT75Mitogen-activated protein kinase 14/0.456
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.456
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.456
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.456
1diuBDMDihydrofolate reductase1.5.1.30.455
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.455
1w0xOLOCyclin-dependent kinase 22.7.11.220.455
1zzlTZYMitogen-activated protein kinase 14/0.455
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.455
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.455
2ix5FADAcyl-coenzyme A oxidase 4, peroxisomal1.3.3.60.455
2j0k4STFocal adhesion kinase 12.7.10.20.455
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.455
2ph5NADHomospermidine synthase/0.455
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.455
2xkeWI2Serine/threonine-protein kinase Nek22.7.11.10.455
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.455
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.455
2yn8STUEphrin type-B receptor 42.7.10.10.455
3gu83GUDeath-associated protein kinase 12.7.11.10.455
3l8p0CEAngiopoietin-1 receptor2.7.10.10.455
3qtzX42Cyclin-dependent kinase 22.7.11.220.455
4bbhNHWGlycylpeptide N-tetradecanoyltransferase/0.455
4f1mACPProbable serine/threonine-protein kinase roco42.7.11.10.455
4n6hEJ4Delta-type opioid receptor/0.455
5e8wSTUTGF-beta receptor type-12.7.11.300.455
1h1r6CPCyclin-dependent kinase 22.7.11.220.454
1rf9DBRCamphor 5-monooxygenase1.14.15.10.454
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.454
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.454
2uzbC75Cyclin-dependent kinase 22.7.11.220.454
2x1nX1NCyclin-dependent kinase 22.7.11.220.454
3cv9VDXVitamin D3 dihydroxylase/0.454
3h0aD30Peroxisome proliferator-activated receptor gamma/0.454
3m08RARDihydrofolate reductase1.5.1.30.454
3r7iX9ICyclin-dependent kinase 22.7.11.220.454
3sruQ26Dihydrofolate reductase1.5.1.30.454
3zh8C58Protein kinase C iota type2.7.11.130.454
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.454
3reyXACAdenosine receptor A2a/0.454
3pwhZMAAdenosine receptor A2a/0.454
1jt6DEQHTH-type transcriptional regulator QacR/0.453
2duv371Cyclin-dependent kinase 22.7.11.220.453
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.453
2zdt46CMitogen-activated protein kinase 102.7.11.240.453
3a62STURibosomal protein S6 kinase beta-12.7.11.10.453
3gubGUBDeath-associated protein kinase 12.7.11.10.453
3nynSGVG protein-coupled receptor kinase 62.7.11.160.453
3roy22ZCyclin-dependent kinase 22.7.11.220.453
4eok4SPCyclin-dependent kinase 22.7.11.220.453
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.453
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
4xumIMNPeroxisome proliferator-activated receptor gamma/0.453
1ec2BEJGag-Pol polyprotein3.4.23.160.452
1s9jBBMDual specificity mitogen-activated protein kinase kinase 12.7.12.20.452
2c5nCK8Cyclin-dependent kinase 22.7.11.220.452
2vf0F89Thymidylate synthase/0.452
2xa4AZ5Tyrosine-protein kinase JAK2/0.452
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.452
3hx4ANPCalmodulin-domain protein kinase 1/0.452
3ormAGSSerine/threonine protein kinase/0.452
3p6nDSOCamphor 5-monooxygenase1.14.15.10.452
3q44D50M1 family aminopeptidase3.4.110.452
3ua506XCytochrome P450 2B61.14.130.452
3uli1N3Cyclin-dependent kinase 22.7.11.220.452
4i22IREEpidermal growth factor receptor2.7.10.10.452
4ia2BIVVitamin D3 receptor A/0.452
4nb6444Nuclear receptor ROR-gamma/0.452
4o701QKBromodomain-containing protein 4/0.452
4qbjNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.452
4ux9ANPMitogen-activated protein kinase 82.7.11.240.452
5iu86DZAdenosine receptor A2a/0.452
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.451
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.451
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.451
3qqfX07Cyclin-dependent kinase 22.7.11.220.451
3rk708ZCyclin-dependent kinase 22.7.11.220.451
3sheI85MAP kinase-activated protein kinase 32.7.11.10.451
4a4xJUPSerine/threonine-protein kinase Nek22.7.11.10.451
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.451
4c4iX20Dual specificity protein kinase TTK2.7.12.10.451
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.451
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.451
4g47TZFMycocyclosin synthase1.14.21.90.451
4ktf1TMCytochrome P450/0.451
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.451
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.451
5iubCLRAdenosine receptor A2a/0.451
5k2dZMAAdenosine receptor A2a/0.451
1i5bANPChemotaxis protein CheA2.7.13.30.450
1pmn984Mitogen-activated protein kinase 102.7.11.240.450
2j0lANPFocal adhesion kinase 12.7.10.20.450
2xk85R1Serine/threonine-protein kinase Nek22.7.11.10.450
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.450
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.450
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.450
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.450
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.450
3q92XNBKetohexokinase/0.450
3r73X87Cyclin-dependent kinase 22.7.11.220.450
3rk507ZCyclin-dependent kinase 22.7.11.220.450
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.450
3wmxNADNAD dependent epimerase/dehydratase/0.450
4c4h7RODual specificity protein kinase TTK2.7.12.10.450
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.450
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.450
4lv8ADPRhoptry protein 5 C/0.450
4qmpDKISerine/threonine-protein kinase 242.7.11.10.450
5k2cZMAAdenosine receptor A2a/0.450
1c6zROCProtease/0.449
1eh4IC1Casein kinase I homolog 12.7.11.10.449
1k6pXN3Gag-Pol polyprotein3.4.23.160.449
2fleAIProtease/0.449
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.449
2uzlC94Cyclin-dependent kinase 22.7.11.220.449
3a60STURibosomal protein S6 kinase beta-12.7.11.10.449
3bhy7CPDeath-associated protein kinase 3/0.449
3eb0DRKUncharacterized protein/0.449
3qtsX46Cyclin-dependent kinase 22.7.11.220.449
3r8pZ46Cyclin-dependent kinase 22.7.11.220.449
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.449
3wv9FEGHmd co-occurring protein HcgE/0.449
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.449
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.449
1aq1STUCyclin-dependent kinase 22.7.11.220.448
1cdeGARPhosphoribosylglycinamide formyltransferase/0.448
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.448
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2bpz3INGag-Pol polyprotein3.4.23.160.448
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.448
2izrBRKCasein kinase I isoform gamma-32.7.11.10.448
2r64740Cyclin-dependent kinase 22.7.11.220.448
2xvdAS6Ephrin type-B receptor 42.7.10.10.448
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
3cgoJNOMitogen-activated protein kinase 102.7.11.240.448
3hz137DHeat shock protein HSP 90-alpha/0.448
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.448
3owaFADAcyl-CoA dehydrogenase/0.448
3rk909ZCyclin-dependent kinase 22.7.11.220.448
3rpv26ZCyclin-dependent kinase 22.7.11.220.448
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.448
4aa4QC0Mitogen-activated protein kinase 14/0.448
4bkjSTIEpithelial discoidin domain-containing receptor 12.7.10.10.448
4c61LMMTyrosine-protein kinase JAK2/0.448
4ea13RXDehydrosqualene synthase/0.448
4elh53IDihydrofolate reductase/0.448
4fv4EK7Mitogen-activated protein kinase 12.7.11.240.448
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.448
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.448
4hni16WCasein kinase I isoform epsilon2.7.11.10.448
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.448
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.448
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.448
5ap57RODual specificity protein kinase TTK2.7.12.10.448
5ckwANPUncharacterized protein/0.448
4uhrNGIAdenosine receptor A2a/0.448
1ke8LS4Cyclin-dependent kinase 22.7.11.220.447
1rbmKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.447
2w1hL0FCyclin-dependent kinase 22.7.11.220.447
2xmyCDKCyclin-dependent kinase 22.7.11.220.447
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.447
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.447
3ezrEZRCyclin-dependent kinase 22.7.11.220.447
3kq7KQ7Mitogen-activated protein kinase 14/0.447
3m8qDJZGag-Pol polyprotein2.7.7.490.447
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.447
3qruX19Cyclin-dependent kinase 22.7.11.220.447
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.447
3t5iSER_SER_CMT_FARRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.447
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4fgh0U6Dihydrofolate reductase1.5.1.30.447
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.447
4hvg19QTyrosine-protein kinase JAK32.7.10.20.447
4kf1HT5Aryldialkylphosphatase3.1.8.10.447
4nks2M2Fibroblast growth factor receptor 1/0.447
4qmzB49Serine/threonine-protein kinase 242.7.11.10.447
4wsqKSAAP2-associated protein kinase 12.7.11.10.447
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.447
5ab7MLCNonspecific lipid-transfer protein, putative/0.447
1hiiC20Gag-Pol polyprotein/0.446
1lcoPPYCytochrome b2, mitochondrial1.1.2.30.446
1oiyN41Cyclin-dependent kinase 22.7.11.220.446
1q5dEPBEpothilone C/D epoxidase1.140.446
1unlRRCCyclin-dependent-like kinase 52.7.11.10.446
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.446
2h96893Mitogen-activated protein kinase 82.7.11.240.446
2hm9TRRDihydrofolate reductase1.5.1.30.446
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.446
2j0j4STFocal adhesion kinase 12.7.10.20.446
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.446
2yixYIXMitogen-activated protein kinase 14/0.446
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.446
2znnS44Peroxisome proliferator-activated receptor alpha/0.446
3fkoFKOMitogen-activated protein kinase 14/0.446
3qwkX62Cyclin-dependent kinase 22.7.11.220.446
3sqq99ZCyclin-dependent kinase 22.7.11.220.446
3vquO22Dual specificity protein kinase TTK2.7.12.10.446
4c4f7CEDual specificity protein kinase TTK2.7.12.10.446
4elb34SDihydrofolate reductase/0.446
4ez50RSCyclin-dependent kinase 62.7.11.220.446
4klaCHDFerrochelatase, mitochondrial4.99.1.10.446
4o2z046Mitogen-activated protein kinase/0.446
4xe606UDihydrofolate reductase1.5.1.30.446
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.446
1egdFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.445
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.445
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
2itzIREEpidermal growth factor receptor2.7.10.10.445
2w06FRVCyclin-dependent kinase 22.7.11.220.445
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.445
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.445
2xclANPPhosphoribosylamine--glycine ligase/0.445
2xru400Aurora kinase A2.7.11.10.445
3oafOAGDihydrofolate reductase1.5.1.30.445
3ttjJBIMitogen-activated protein kinase 102.7.11.240.445
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.445
4a84DXCMajor pollen allergen Bet v 1-A/0.445
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.445
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.445
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.445
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.445
4xbfFADLysine-specific histone demethylase 1A10.445
4yuqKS1Calmodulin-like domain protein kinase/0.445
1k6cMK1Gag-Pol polyprotein3.4.23.160.444
1l2tATPUncharacterized ABC transporter ATP-binding protein MJ0796/0.444
1ouy094Mitogen-activated protein kinase 14/0.444
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.444
1zhzERGOxysterol-binding protein homolog 4/0.444
2bpw1INGag-Pol polyprotein3.4.23.160.444
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.444
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.444
2r0cFADPutative FAD-monooxygenase/0.444
2upjU02Gag-Pol polyprotein3.4.23.160.444
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.444
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.444
3c4wATPRhodopsin kinase/0.444
3i60E86Mitogen-activated protein kinase 12.7.11.240.444
3qiyQI1Botulinum neurotoxin type A3.4.24.690.444
3qm4PN0Cytochrome P450 2D6/0.444
3ral04ZCyclin-dependent kinase 22.7.11.220.444
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.444
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.444
4fko20KCyclin-dependent kinase 22.7.11.220.444
4fkw62KCyclin-dependent kinase 22.7.11.220.444
4g170VNCasein kinase I isoform gamma-32.7.11.10.444
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.444
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.444
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.444
4nka2K7Fibroblast growth factor receptor 1/0.444
5dr9SKEAurora kinase A2.7.11.10.444
1w2cANPInositol-trisphosphate 3-kinase A2.7.1.1270.443
1zrzBI1Protein kinase C iota type2.7.11.130.443
2b55D31Cyclin-dependent kinase 22.7.11.220.443
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.443
2jedLG8Protein kinase C theta type2.7.11.130.443
2pvnP63Casein kinase II subunit alpha2.7.11.10.443
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.443
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.443
2wxvWXVCyclin-dependent kinase 22.7.11.220.443
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.443
3d74NBBPheromone-binding protein ASP1/0.443
3fmn530Mitogen-activated protein kinase 14/0.443
3p3e3P3UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.443
3r71X86Cyclin-dependent kinase 22.7.11.220.443
3r7yZ04Cyclin-dependent kinase 22.7.11.220.443
3rpo24ZCyclin-dependent kinase 22.7.11.220.443
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.443
4eor4SPCyclin-dependent kinase 22.7.11.220.443
4f640S8Fibroblast growth factor receptor 1/0.443
4fkr45KCyclin-dependent kinase 22.7.11.220.443
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.443
4gt3ATPMitogen-activated protein kinase 12.7.11.240.443
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.443
4kd11QKCyclin-dependent kinase 22.7.11.220.443
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.443
3sn6P0GBeta-2 adrenergic receptor/0.443
3uzcT4EAdenosine receptor A2a/0.443
1fvt106Cyclin-dependent kinase 22.7.11.220.442
1iyzNDPProbable quinone oxidoreductase/0.442
1yt9OISGag-Pol polyprotein/0.442
1zeoC01Peroxisome proliferator-activated receptor gamma/0.442
1zyjBI5Mitogen-activated protein kinase 14/0.442
2c6mDT5Cyclin-dependent kinase 22.7.11.220.442
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.442
2hk51BMTyrosine-protein kinase HCK2.7.10.20.442
2izt23DCasein kinase I isoform gamma-32.7.11.10.442
2w5bAGSSerine/threonine-protein kinase Nek22.7.11.10.442
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.442
3acw651Dehydrosqualene synthase/0.442
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.442
3el4ROCGag-Pol polyprotein3.4.23.160.442
3em6017Gag-Pol polyprotein3.4.23.160.442
3ez2ADPPlasmid partition protein A/0.442
3fl4FL4Mitogen-activated protein kinase 14/0.442
3itzP66Mitogen-activated protein kinase 14/0.442
3lfeZ84Mitogen-activated protein kinase 14/0.442
3o0iP54Heat shock protein HSP 90-alpha/0.442
3qtxX43Cyclin-dependent kinase 22.7.11.220.442
3rqjY2BNitric oxide synthase, brain1.14.13.390.442
3svqJK4Nitric oxide synthase, brain1.14.13.390.442
3unj0BXCyclin-dependent kinase 22.7.11.220.442
4bgg844Activin receptor type-12.7.11.300.442
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4fkv61KCyclin-dependent kinase 22.7.11.220.442
4hnf16WCasein kinase I isoform delta2.7.11.10.442
4iaq2GM5-hydroxytryptamine receptor 1B/0.442
4jvlESTEstrogen sulfotransferase2.8.2.40.442
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
4ykgFADAlkyl hydroperoxide reductase subunit F1.8.10.442
1finATPCyclin-dependent kinase 22.7.11.220.441
1i59ANPChemotaxis protein CheA2.7.13.30.441
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.441
1r78FMDCyclin-dependent kinase 22.7.11.220.441
1vyzN5BCyclin-dependent kinase 22.7.11.220.441
1x8b824Wee1-like protein kinase2.7.10.20.441
2r3r6SCCyclin-dependent kinase 22.7.11.220.441
2rjp886A disintegrin and metalloproteinase with thrombospondin motifs 43.4.24.820.441
2vd5BI8Myotonin-protein kinase2.7.11.10.441
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.441
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.441
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.441
3dxjNE6DNA-directed RNA polymerase subunit beta/0.441
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.441
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.441
3ig7EFPCyclin-dependent kinase 22.7.11.220.441
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.441
3rm719ZCyclin-dependent kinase 22.7.11.220.441
3sw418KCyclin-dependent kinase 22.7.11.220.441
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.441
3vt8YI3Vitamin D3 receptor/0.441
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.441
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.441
4fks46KCyclin-dependent kinase 22.7.11.220.441
4ia3BIVVitamin D3 receptor A/0.441
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.441
4o71CPBBromodomain-containing protein 4/0.441
4ryvZEAProtein LlR18A/0.441
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.441
5ab6CAANonspecific lipid-transfer protein, putative/0.441
1npa3NHGag-Pol polyprotein3.4.23.160.440
1npwLGZGag-Pol polyprotein3.4.23.160.440
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
2i40BLZCyclin-dependent kinase 22.7.11.220.440
2itpAEEEpidermal growth factor receptor2.7.10.10.440
2q641UNGag-Pol polyprotein3.4.23.160.440
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.440
2r3jSCJCyclin-dependent kinase 22.7.11.220.440
2vwy7X5Ephrin type-B receptor 42.7.10.10.440
2wotZZGTGF-beta receptor type-12.7.11.300.440
2xkc4VQSerine/threonine-protein kinase Nek22.7.11.10.440
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3qzgX67Cyclin-dependent kinase 22.7.11.220.440
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.440
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440
4b7dQLECytochrome P450 monooxygenase PikC/0.440
4brxKGWFocal adhesion kinase 12.7.10.20.440
4e730NRMitogen-activated protein kinase 82.7.11.240.440
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.440
4ia1BIVVitamin D3 receptor A/0.440
4irnFADAnaB/0.440
4ktkKTKCytochrome P450/0.440
5iua6DXAdenosine receptor A2a/0.440