Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ful | 52D | Leukotriene A-4 hydrolase | 3.3.2.6 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3ful | 52D | Leukotriene A-4 hydrolase | 3.3.2.6 | 1.000 | |
| 3fui | 812 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.706 | |
| 4rsy | B3N | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.684 | |
| 3fuj | 00G | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.612 | |
| 3fun | 798 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.603 | |
| 3chs | 4BU | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.530 | |
| 3fu5 | 492 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.476 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.446 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.442 |