Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3fuh | BES | Leukotriene A-4 hydrolase | 3.3.2.6 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3fuh | BES | Leukotriene A-4 hydrolase | 3.3.2.6 | 1.000 | |
| 3ftx | BES | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.629 | |
| 2r59 | PH0 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.608 | |
| 4gaa | BES | Leukotriene A(4) hydrolase | / | 0.580 | |
| 3fuf | BES | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.469 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.453 |