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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3fufBESLeukotriene A-4 hydrolase3.3.2.6

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3fufBESLeukotriene A-4 hydrolase3.3.2.61.000
3ftxBESLeukotriene A-4 hydrolase3.3.2.60.922
2r59PH0Leukotriene A-4 hydrolase3.3.2.60.643
3fuhBESLeukotriene A-4 hydrolase3.3.2.60.613
4gaaBESLeukotriene A(4) hydrolase/0.608
2xq0BESLeukotriene A-4 hydrolase homolog3.3.2.60.517
2zs8ADPPantothenate kinase2.7.1.330.453
3aezGDPPantothenate kinase2.7.1.330.453
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.453
2hptBESAminopeptidase N3.4.11.20.446