sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3fpz | AHZ | Thiamine thiazole synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3fpz | AHZ | Thiamine thiazole synthase | / | 1.000 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.522 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.471 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.461 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.454 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.450 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.447 | |
| 4d04 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.447 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 0.446 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.444 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.444 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.444 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.444 | |
| 3gwd | FAD | Cyclohexanone monooxygenase | / | 0.443 | |
| 4c5o | FAD | Putative monooxygenase | / | 0.443 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.442 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.442 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.441 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.441 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.441 |