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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3fpaDTBATP-dependent dethiobiotin synthetase BioD

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3fpaDTBATP-dependent dethiobiotin synthetase BioD/1.000
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.504
2rcyNAPPyrroline-5-carboxylate reductase/0.499
3dm6757Beta-secretase 13.4.23.460.498
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.497
2i3gNAPN-acetyl-gamma-glutamyl-phosphate reductase1.2.1.380.495
3to6LYS_CMCHistone acetyltransferase ESA1/0.494
4dpi0N1Beta-secretase 13.4.23.460.492
3atyFMNProstaglandin F2a synthase/0.491
1nvtNAPShikimate dehydrogenase (NADP(+))/0.489
2h3wCOACarnitine O-acetyltransferase2.3.1.70.489
1ds7FMNOxygen-insensitive NAD(P)H nitroreductase/0.488
4a0rDTBBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial6.3.3.30.487
4a6cQG9Gag-Pol polyprotein3.4.23.160.487
4wjiNAPPutative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase/0.487
3atzFMNProstaglandin F2a synthase/0.486
3gqvNAPEnoyl reductase LovC10.486
3lpiZ74Beta-secretase 13.4.23.460.486
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.484
3b70NAPEnoyl reductase LovC10.484
3gfbNADL-threonine 3-dehydrogenase/0.484
3lpkZ76Beta-secretase 13.4.23.460.484
4ambDUDPutative glycosyl transferase/0.483
3bgbLJGGag-Pol polyprotein3.4.23.160.482
3ge1ADPGlycerol kinase/0.482
2p83MR0Beta-secretase 13.4.23.460.481
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.481
1c9k5GPBifunctional adenosylcobalamin biosynthesis protein CobU/0.480
1bwsNDPGDP-L-fucose synthase/0.479
2jn3JN3Fatty acid-binding protein, liver/0.479
4e2bFMNDehydrogenase/0.479
1bwaXV6Gag-Pol polyprotein3.4.23.160.478
1fwkADPHomoserine kinase2.7.1.390.478
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.478
3tjzGNPADP-ribosylation factor 1/0.478
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.477
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.477
3c1y2BADNA integrity scanning protein DisA/0.477
3f1kNAPUncharacterized oxidoreductase YciK10.477
1cbqRE9Cellular retinoic acid-binding protein 2/0.476
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.476
1qrpHH0Pepsin A-43.4.23.10.476
2ou2ACOHistone acetyltransferase KAT5/0.476
4e2dFMNDehydrogenase/0.476
4r81FMNPredicted NADH dehydrogenase/0.476
2ywwATPAspartate carbamoyltransferase regulatory chain/0.474
3ukoNADAlcohol dehydrogenase class-3/0.474
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.474
1psa0ZLPepsin A3.4.23.10.473
2oapANPType II secretion system protein (GspE-2)/0.473
3cluFADElectron transfer flavoprotein subunit alpha/0.473
3skgPB8Beta-secretase 13.4.23.460.473
1p0hACOMycothiol acetyltransferase2.3.1.1890.472
3dafFEG5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.472
4hwkNAPSepiapterin reductase1.1.1.1530.472
1k6tXN1Gag-Pol polyprotein3.4.23.160.471
1mjaCOAHistone acetyltransferase ESA1/0.471
2d8aNADL-threonine 3-dehydrogenase/0.471
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.471
2xgs44PUncharacterized protein/0.471
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.471
3gy0NAPNAD(P)-dependent oxidoreductase/0.471
3k5c0BIBeta-secretase 13.4.23.460.471
1c6yMK1Protease/0.470
2dfvNADL-threonine 3-dehydrogenase/0.470
2ebaFADPutative glutaryl-CoA dehydrogenase/0.470
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.470
2iko7IGRenin3.4.23.150.470
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.470
3dagFEG5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.470
3p62FMNPentaerythritol tetranitrate reductase/0.470
4h4yNAPBiphenyl dioxygenase ferredoxin reductase subunit/0.470
4z26FADPutative GMC-type oxidoreductase R13510.470
1n2hPAJPantothenate synthetase6.3.2.10.469
2wkz5AHGag-Pol polyprotein/0.469
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.468
2qbuSAHPrecorrin-2 methyltransferase/0.468
3cib314Beta-secretase 13.4.23.460.468
3in6FMNUncharacterized protein/0.468
3lqfNADGalactitol dehydrogenase/0.468
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.468
4nieNBHNuclear receptor ROR-gamma/0.468
1fm6BRLPeroxisome proliferator-activated receptor gamma/0.467
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.467
2y05NAPProstaglandin reductase 1/0.467
3cic316Beta-secretase 13.4.23.460.467
3cisATPUniversal stress protein Rv2623/0.467
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.467
3vg10GTBeta-secretase 13.4.23.460.467
4k8s1QTBeta-secretase 13.4.23.460.467
1lluNADAlcohol dehydrogenase/0.466
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.466
2vnaNAPProstaglandin reductase 21.3.1.480.466
3hyoADPPyridoxal kinase/0.466
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.466
3qlsNDPDihydrofolate reductase1.5.1.30.466
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4dfg0JVGag-Pol polyprotein3.4.23.160.466
1v0jFADUDP-galactopyranose mutase5.4.99.90.465
2e20B4PPropionate kinase/0.465
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.465
3bgcLJHGag-Pol polyprotein3.4.23.160.465
3oibFDAPutative acyl-CoA dehydrogenase/0.465
3qwbNDPProbable quinone oxidoreductase1.6.5.50.465
3toxNAPPutative oxidoreductase/0.465
4gid0GHBeta-secretase 13.4.23.460.465
2pauD5M5'-deoxynucleotidase YfbR/0.464
3pxvFMNNitroreductase/0.464
3rn8RN8Glutamate receptor 2/0.464
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.464
4exg916Beta-secretase 13.4.23.460.464
4g7gVFVLanosterol 14-alpha-demethylase/0.464
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.464
4kqwNAPKetol-acid reductoisomerase (NADP(+))/0.464
1h6bNDPGlucose--fructose oxidoreductase1.1.99.280.463
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.463
1yb5NAPQuinone oxidoreductase1.6.5.50.463
2f3eAXQBeta-secretase 13.4.23.460.463
3gwdNAPCyclohexanone monooxygenase/0.463
3phiNDPShikimate dehydrogenase (NADP(+))/0.463
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.463
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.463
4lxa1YSBeta-secretase 13.4.23.460.463
1bwb146Gag-Pol polyprotein3.4.23.160.462
1xs7MMIBeta-secretase 13.4.23.460.462
2fdpFRPBeta-secretase 13.4.23.460.462
2vbdV10Isopenicillin N synthase1.21.3.10.462
3i7eDJRGag-Pol polyprotein/0.462
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
4lj6ACPChaperone protein ClpB/0.462
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.462
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.461
1lbcCYZGlutamate receptor 2/0.461
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.461
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.461
3ai2NDPNADPH-sorbose reductase/0.461
3cid318Beta-secretase 13.4.23.460.461
3ekuCY9Actin-5C/0.461
3ieuGDPGTPase Era/0.461
3nsh957Beta-secretase 13.4.23.460.461
3p67FMNPentaerythritol tetranitrate reductase/0.461
3rpeFADPutative modulator of drug activity/0.461
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.461
4ej0NAPADP-L-glycero-D-manno-heptose-6-epimerase/0.461
4i0i957Beta-secretase 13.4.23.460.461
1xddAAYIntegrin alpha-L/0.460
2g247IGRenin3.4.23.150.460
2qnqQN3Gag-Pol polyprotein3.4.23.160.460
2wdzNADGalactitol dehydrogenase/0.460
3duyAFJBeta-secretase 13.4.23.460.460
3w0nANPHygromycin-B 4-O-kinase2.7.1.1630.460
4a6bQG8Gag-Pol polyprotein3.4.23.160.460
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.460
4uunNAIL-lactate dehydrogenase/0.460
5ahsFADAcyl-CoA dehydrogenase/0.460
1bwfATFGlycerol kinase/0.459
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.459
2geuCOKPantothenate kinase2.7.1.330.459
2j3kNAPNADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.459
2wf1ZY1Beta-secretase 13.4.23.460.459
3dk1G05Gag-Pol polyprotein3.4.23.160.459
3iocA5DPantothenate synthetase6.3.2.10.459
3own3OXRenin3.4.23.150.459
4b2gV1NUncharacterized protein/0.459
4j7uNAPSepiapterin reductase1.1.1.1530.459
4xiwAZMCarbonic anhydrase, alpha type/0.459
5a3bAPRSIR2 family protein/0.459
1hskFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.458
1mj9COAHistone acetyltransferase ESA1/0.458
1mjbACOHistone acetyltransferase ESA1/0.458
2yimMC4Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.458
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.458
3f46I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.458
3slkNDPPolyketide synthase extender module 2/0.458
4a99FADTetX family tetracycline inactivation enzyme/0.458
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.458
4k9h1QUBeta-secretase 13.4.23.460.458
4z24FADPutative GMC-type oxidoreductase R13510.458
1x1dSAHC-20 methyltransferase/0.457
2bb9AKCGag-Pol polyprotein3.4.23.160.457
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.457
2givACOHistone acetyltransferase KAT8/0.457
2j09FADDeoxyribodipyrimidine photo-lyase4.1.99.30.457
2r43G3GGag-Pol polyprotein3.4.23.160.457
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.457
3k4nFADPyranose 2-oxidase/0.457
3lpjZ75Beta-secretase 13.4.23.460.457
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.457
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.457
4yxm2BADNA integrity scanning protein DisA/0.457
2g1r3IGRenin3.4.23.150.456
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.456
2j3iNAPNADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.456
2vkeTACTetracycline repressor protein class D/0.456
3coy53HPantothenate synthetase6.3.2.10.456
3qe2FMNNADPH--cytochrome P450 reductase/0.456
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.456
1icuFMNOxygen-insensitive NAD(P)H nitroreductase/0.455
1tehNADAlcohol dehydrogenase class-31.1.1.10.455
1xe55FEPlasmepsin-23.4.23.390.455
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.455
2e77FMNLactate oxidase/0.455
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.455
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.455
3gw9VNILanosterol 14-alpha-demethylase/0.455
3l0lHC3Nuclear receptor ROR-gamma/0.455
3r7kFDAProbable acyl CoA dehydrogenase/0.455
4djaFAD(6-4) photolyase/0.455
4h9tHL4Phosphotriesterase/0.455
4jicFMNGTN Reductase/0.455
4rnuFMNNADPH dehydrogenase 11.6.99.10.455
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.454
1i59ANPChemotaxis protein CheA2.7.13.30.454
1j49NADD-lactate dehydrogenase1.1.1.280.454
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.454
2ahrNAPPyrroline-5-carboxylate reductase/0.454
3imgBZ2Pantothenate synthetase6.3.2.10.454
3q71AR6Poly [ADP-ribose] polymerase 142.4.2.300.454
3up0D7SaceDAF-12/0.454
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.454
4euaCOASuccinyl-CoA:acetate CoA-transferase/0.454
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.454
4jbiNDPAlcohol dehydrogenase (Zinc)/0.454
4loi1YCStimulator of interferon genes protein/0.454
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.454
4xxvNAD3-isopropylmalate dehydrogenase/0.454
1h63FMNPentaerythritol tetranitrate reductase/0.453
1h6cNDPGlucose--fructose oxidoreductase1.1.99.280.453
2ag5NAD3-hydroxybutyrate dehydrogenase type 2/0.453
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.453
2fy5SOPCholine O-acetyltransferase2.3.1.60.453
2xlrFADPutative flavin-containing monooxygenase/0.453
3c212BADNA integrity scanning protein DisA/0.453
3cobADPKinesin heavy chain-like protein/0.453
3ohh3HHBeta-secretase 13.4.23.460.453
3r2fPB0Beta-secretase 13.4.23.460.453
3unk0BYCyclin-dependent kinase 22.7.11.220.453
3w8eNAD3-hydroxybutyrate dehydrogenase/0.453
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.453
4g3jVNTLanosterol 14-alpha-demethylase/0.453
4ktoFADPutative isovaleryl-CoA dehydrogenase protein/0.453
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.452
1edoNAP3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic1.1.1.1000.452
1hwzNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.452
1nzdUPGDNA beta-glucosyltransferase/0.452
1o0sNAINAD-dependent malic enzyme, mitochondrial1.1.1.380.452
1x1bSAHC-20 methyltransferase/0.452
2eixFADNADH-cytochrome b5 reductase/0.452
2obyNAPQuinone oxidoreductase PIG310.452
2xpuTDCTetracycline repressor protein class D/0.452
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.452
3jynNDPQuinone oxidoreductase/0.452
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.452
3qbhQBHBeta-secretase 13.4.23.460.452
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.452
3sx2NADUncharacterized protein/0.452
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.452
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.452
4h50NAPBiphenyl dioxygenase ferredoxin reductase subunit/0.452
4k36SAMAnaerobic sulfatase-maturating enzyme1.8.980.452
1bxsNADRetinal dehydrogenase 11.2.1.360.451
1e3eNAIAlcohol dehydrogenase 41.1.1.10.451
1w6hTITPlasmepsin-23.4.23.390.451
2f3fAXFBeta-secretase 13.4.23.460.451
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
2vf0F89Thymidylate synthase/0.451
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.451
3bk2U5PRibonuclease J/0.451
3f03FMNPentaerythritol tetranitrate reductase/0.451
3hazFADBifunctional protein PutA/0.451
3k5gBJCBeta-secretase 13.4.23.460.451
3kybFADUDP-galactopyranose mutase5.4.99.90.451
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.451
3p74FMNPentaerythritol tetranitrate reductase/0.451
3up4NAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.451
4b8wNAPGDP-L-fucose synthase1.1.1.2710.451
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
4dbzNDPPutative ketoacyl reductase1.3.10.451
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.451
4h4wNAPBiphenyl dioxygenase ferredoxin reductase subunit/0.451
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.451
5a3cNADSIR2 family protein/0.451
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.451
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
1egdFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.450
1kqoDNDNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.450
1sguMK1Gag-Pol polyprotein3.4.23.160.450
1ybmNAPUncharacterized protein At5g02240/0.450
1zdwFLVPrenyltransferase/0.450
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.450
2fzwNADAlcohol dehydrogenase class-31.1.1.10.450
2g226IGRenin3.4.23.150.450
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.450
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.450
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.450
3b20NADGlyceraldehyde-3-phosphate dehydrogenase/0.450
3b2eADPATPase GET3/0.450
3h4lANPDNA mismatch repair protein PMS1/0.450
3ixk929Beta-secretase 13.4.23.460.450
4kcfAKMFAD-dependent oxidoreductase/0.450
1b8vNADMalate dehydrogenase/0.449
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.449
1g0nNDPTetrahydroxynaphthalene reductase1.1.1.2520.449
1h74AGSHomoserine kinase2.7.1.390.449
1hpxKNIGag-Pol polyprotein/0.449
2c3qGTXGlutathione S-transferase theta-12.5.1.180.449
2d29FADAcyl-CoA dehydrogenase/0.449
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2oahQINBeta-secretase 13.4.23.460.449
2pamTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.449
2r0cFADPutative FAD-monooxygenase/0.449
2r8pT6FTransketolase 1/0.449
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
2xviFADPutative flavin-containing monooxygenase/0.449
2yylFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.449
3clrFADElectron transfer flavoprotein subunit alpha/0.449
3clsFADElectron transfer flavoprotein subunit alpha/0.449
3ggoNAIPrephenate dehydrogenase/0.449
3h86AP5Adenylate kinase/0.449
3ixp834Ecdysone receptor/0.449
3mzhCMPCRP-like cAMP-activated global transcriptional regulator/0.449
3r5yF42Uncharacterized protein/0.449
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.449
4oplFDAConserved Archaeal protein/0.449
4q71FADBifunctional protein PutA/0.449
1c6x3INProtease/0.448
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1k6pXN3Gag-Pol polyprotein3.4.23.160.448
1rj6AZMCarbonic anhydrase 144.2.1.10.448
2c12FADNitroalkane oxidase1.7.3.10.448
2wf4ZY4Beta-secretase 13.4.23.460.448
3d8bADPFidgetin-like protein 13.6.40.448
3eksCY9Actin-5C/0.448
3jzdNADMaleylacetate reductase/0.448
3kpbSAMUncharacterized protein MJ0100/0.448
4a0mNADBetaine aldehyde dehydrogenase, chloroplastic1.2.1.80.448
4iacACPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.448
4ku5DCC3-oxoacyl-[ACP] synthase III/0.448
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.448
1d0mBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.447
1f8fNADBenzyl alcohol dehydrogenase/0.447
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.447
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1knrFADL-aspartate oxidase1.4.3.160.447
1rfvADPPyridoxal kinase2.7.1.350.447
1tsxUMPThymidylate synthase/0.447
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.447
2avvMK1Gag-Pol polyprotein3.4.23.160.447
2cy0NAPShikimate dehydrogenase (NADP(+))/0.447
2dteNAIGlucose 1-dehydrogenase related protein/0.447
2g8yNADHydroxycarboxylate dehydrogenase B/0.447
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.447
2ignFADPyranose 2-oxidase/0.447
2vj6VG5Beta-secretase 13.4.23.460.447
2w3bNDPDihydrofolate reductase1.5.1.30.447
2y0mACOHistone acetyltransferase KAT8/0.447
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.447
2ylrNAPPhenylacetone monooxygenase1.14.13.920.447
3flwFLWMitogen-activated protein kinase 14/0.447
3v2uATPProtein GAL3/0.447
3veu0GOBeta-secretase 13.4.23.460.447
4b8zNAPGDP-L-fucose synthase1.1.1.2710.447
4ez8DHFThymidylate synthase2.1.1.450.447
4fj2NAP17beta-hydroxysteroid dehydrogenase/0.447
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.447
4q73FADBifunctional protein PutA/0.447
4yryFADGlutamate synthase, beta subunit/0.447
1fxsNAPGDP-L-fucose synthase/0.446
1t2aNDPGDP-mannose 4,6 dehydratase4.2.1.470.446
2freFMNNAD(P)H-flavin oxidoreductase/0.446
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.446
2g20L1ARenin3.4.23.150.446
2q4bNAPUncharacterized protein At5g02240/0.446
2y60M8FIsopenicillin N synthase1.21.3.10.446
3a4vNADNDP-sugar epimerase/0.446
3fql79ZGenome polyprotein2.7.7.480.446
3sz0FADSulfide-quinone reductase/0.446
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.446
4at0FADPossible succinate dehydrogenase/0.446
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.446
4ewo996Beta-secretase 13.4.23.460.446
4iarERM5-hydroxytryptamine receptor 1B/0.446
4l9kEHFSerum albumin/0.446
5d3qGDPDynamin-13.6.5.50.446
5dldUD1UDP-N-Acetylglucosamine 2-epimerase/0.446
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.446
5itzLOCTubulin beta-2B chain/0.446
1j4jACOAcetyltransferase2.3.10.445
1kkq471Peroxisome proliferator-activated receptor alpha/0.445
1ra3NAPDihydrofolate reductase1.5.1.30.445
1rfuADPPyridoxal kinase2.7.1.350.445
1tqf32PBeta-secretase 13.4.23.460.445
2fy4COACholine O-acetyltransferase2.3.1.60.445
2igoFADPyranose 2-oxidase/0.445
2iqgF2IBeta-secretase 13.4.23.460.445
2qs1UB1Glutamate receptor ionotropic, kainate 1/0.445
2vijC44Beta-secretase 13.4.23.460.445
2ym2FADPhenylacetone monooxygenase1.14.13.920.445
3cz7ACOHistone acetyltransferase RTT1092.3.1.480.445
3dv5BAVBeta-secretase 13.4.23.460.445
3ecg065Gag-Pol polyprotein3.4.23.470.445
3fcjFADNitroalkane oxidase1.7.3.10.445
3gbuATPUncharacterized sugar kinase PH14592.7.10.445
3iltTRUGlutamate receptor 2/0.445
3kpkFADSulfide-quinone reductase/0.445
3nxxNDPDihydrofolate reductase1.5.1.30.445
3ohf3HFBeta-secretase 13.4.23.460.445
3oxv478Gag-Pol polyprotein3.4.23.160.445
3p3c3P3UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.445
4impNDPPolyketide synthase extender modules 3-4/0.445
4yaoFMNNADPH--cytochrome P450 reductase/0.445
5e7oMGDDMSO reductase family type II enzyme, molybdopterin subunit/0.445
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.444
1hf3NADAlcohol dehydrogenase E chain1.1.1.10.444
1i9c5ADGlutamate mutase epsilon subunit/0.444
1kh3ANPArgininosuccinate synthase/0.444
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.444
1mtrPI6Gag-Pol polyprotein3.4.23.160.444
1p9wANPType II secretion system protein E/0.444
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.444
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.444
2fzeAPRAlcohol dehydrogenase class-31.1.1.10.444
2q3kMUWGag-Pol polyprotein/0.444
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.444
3a1nNADNDP-sugar epimerase/0.444
3ixj586Beta-secretase 13.4.23.460.444
3k5dXLIBeta-secretase 13.4.23.460.444
3keuATPPyridoxal kinase2.7.1.350.444
3pfdFDAAcyl-CoA dehydrogenase FadE25/0.444
3qaaG04Gag-Pol polyprotein3.4.23.160.444
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.444
3t3c017Gag-Pol polyprotein3.4.23.160.444
4acxS8ZBeta-secretase 13.4.23.460.444
4kl9NDPDihydrofolate reductase1.5.1.30.444
4l04NAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.444
1bv9XV6Gag-Pol polyprotein3.4.23.160.443
1c70L75Protease/0.443
1d4hBEHGag-Pol polyprotein3.4.23.160.443
1h6dNDPGlucose--fructose oxidoreductase1.1.99.280.443
1knpFADL-aspartate oxidase1.4.3.160.443
1kzkJE2Gag-Pol polyprotein3.4.23.160.443
1obbNADAlpha-glucosidase3.2.1.200.443
1pz0NAPProtein IolS1.1.10.443
1qrrUPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.443
1xnjADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 12.7.1.250.443
1ykfNAPNADP-dependent isopropanol dehydrogenase1.1.1.800.443
2b3dFADModulator of drug activity B/0.443
2bpw1INGag-Pol polyprotein3.4.23.160.443
2c27ACOMycothiol acetyltransferase2.3.1.1890.443
2cmvNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.443
2q0kNAPThioredoxin reductase1.8.1.90.443
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.443
2zb3NDPProstaglandin reductase 21.3.1.480.443
3b6zCO7Enoyl reductase LovC10.443
3cosNADAlcohol dehydrogenase 41.1.1.10.443
3dmeFADPutative conserved exported protein/0.443
3s1dZIRCytokinin dehydrogenase 11.5.99.120.443
4a33MYAGlycylpeptide N-tetradecanoyltransferase/0.443
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.443
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.443
4gl4NAIAlcohol dehydrogenase class-3/0.443
4lcg1WMUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.443
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.443
4ohwATPProtein clpf-1/0.443
4zlaBESCytosol aminopeptidase3.4.11.10.443
5idwNAPShort-chain dehydrogenase/reductase SDR/0.443
1bim0QBRenin3.4.23.150.442
1k6vXN2Gag-Pol polyprotein3.4.23.160.442
1n7hNDPGDP-mannose 4,6 dehydratase 24.2.1.470.442
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.442
1s5kCOAAminoglycoside N(6')-acetyltransferase type 1/0.442
1yqdNAPSinapyl alcohol dehydrogenase/0.442
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.442
2e1zB4PPropionate kinase/0.442
2oxtSAMGenome polyprotein/0.442
2vn0TDZCytochrome P450 2C8/0.442
2y6o1N1Ephrin type-A receptor 42.7.10.10.442
3cyw017Gag-Pol polyprotein3.4.23.160.442
3f6sFMNFlavodoxin/0.442
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.442
3o9hK2EGag-Pol polyprotein/0.442
3s3tATPUniversal stress protein/0.442
3zoiM2WIsopenicillin N synthase1.21.3.10.442
4c49HCYCorticosteroid-binding globulin/0.442
4dpf0LGBeta-secretase 13.4.23.460.442
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.442
4l8u9AZSerum albumin/0.442
4q72FADBifunctional protein PutA/0.442
4r20AERCytochrome P450 family 17 polypeptide 2/0.442
4wriOKAOkadaic acid binding protein 2-alpha/0.442
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
1bdmNAXMalate dehydrogenase/0.441
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.441
1icvFMNOxygen-insensitive NAD(P)H nitroreductase/0.441
1jnzFADAdenylylsulfate reductase, subunit A (AprA)/0.441
1p4mADPRiboflavin kinase2.7.1.260.441
2abbFMNPentaerythritol tetranitrate reductase/0.441
2ejvNADL-threonine 3-dehydrogenase/0.441
2ft9CHDFatty acid-binding protein 2, liver/0.441
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.441
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.441
2xvq9DSSerum albumin/0.441
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.441
3bmoNAPPteridine reductase/0.441
3dv1AR9Beta-secretase 13.4.23.460.441
3em4DR7Gag-Pol polyprotein3.4.23.160.441
3fvlBHKCarboxypeptidase A13.4.17.10.441
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.441
3ik6HCZGlutamate receptor 2/0.441
3ttp017Gag-Pol polyprotein3.4.23.160.441
4bkqNAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
4bmsNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.441
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.441
4mdhNADMalate dehydrogenase, cytoplasmic1.1.1.370.441
4n9wGDPPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.441
4nesUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.441
4uymVOR14-alpha sterol demethylase Cyp51B/0.441
4ww0ADPATP-dependent zinc metalloprotease FtsH/0.441
1m4dCOAAminoglycoside 2'-N-acetyltransferase2.3.10.440
1ma0NADAlcohol dehydrogenase class-31.1.1.10.440
1npa3NHGag-Pol polyprotein3.4.23.160.440
1npwLGZGag-Pol polyprotein3.4.23.160.440
1nzfUPGDNA beta-glucosyltransferase/0.440
1pzfA3DLactate dehydrogenase/0.440
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.440
1t7kBH0Gag-Pol polyprotein3.4.23.160.440
1tw4CHDFatty acid-binding protein, liver/0.440
1v4sMRKGlucokinase2.7.1.20.440
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.440
2fj1CTCTetracycline repressor protein class D/0.440
2fznFADBifunctional protein PutA1.5.5.20.440
2g94ZPQBeta-secretase 13.4.23.460.440
2gd6ACOProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.440
2hfuMEVMevalonate kinase/0.440
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.440
2il2LIXRenin3.4.23.150.440
2iviACWIsopenicillin N synthase1.21.3.10.440
2v6gNAP3-oxo-Delta(4,5)-steroid 5-beta-reductase/0.440
2zfaFMNLactate oxidase/0.440
2zvcSAHPrecorrin-3 C17-methyltransferase/0.440
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.440
3acy702Dehydrosqualene synthase/0.440
3bgxMEFThymidylate synthase/0.440
3fr5I4AFatty acid-binding protein, adipocyte/0.440
3rusADPChaperonin/0.440
3sdi3SDProteasome subunit beta type-53.4.25.10.440
3sdi3SDProteasome subunit beta type-63.4.25.10.440
3tnlNADShikimate dehydrogenase (NADP(+))/0.440
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.440
3vglANPGlucokinase/0.440
3w6uNAP6-phosphogluconate dehydrogenase, NAD-binding protein/0.440
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.440
4l03NAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.440
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.440