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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3flwFLWMitogen-activated protein kinase 14

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3flwFLWMitogen-activated protein kinase 14/1.000
3flyFLYMitogen-activated protein kinase 14/0.684
3flzFLZMitogen-activated protein kinase 14/0.679
3fmh533Mitogen-activated protein kinase 14/0.679
3fklFKLMitogen-activated protein kinase 14/0.670
3fln3FNMitogen-activated protein kinase 14/0.657
3fi4FI4Mitogen-activated protein kinase 14/0.649
3fmkFMKMitogen-activated protein kinase 14/0.620
3fskRO6Mitogen-activated protein kinase 14/0.607
3nww3NWMitogen-activated protein kinase 14/0.550
4lopSB4Mitogen-activated protein kinase 14/0.547
4aa4QC0Mitogen-activated protein kinase 14/0.541
2ghlLIBMitogen-activated protein kinase 14/0.536
3fmn530Mitogen-activated protein kinase 14/0.536
3iphG11Mitogen-activated protein kinase 14/0.534
4aacAAVMitogen-activated protein kinase 14/0.531
3dt1P40Mitogen-activated protein kinase 14/0.528
3flsFLSMitogen-activated protein kinase 14/0.527
2balPQAMitogen-activated protein kinase 14/0.525
4kiq1RAMitogen-activated protein kinase 14/0.521
4loqSB4Mitogen-activated protein kinase 14/0.520
4looSB4Mitogen-activated protein kinase 14/0.518
1ouk084Mitogen-activated protein kinase 14/0.516
4aa5NQBMitogen-activated protein kinase 14/0.516
3hl7I47Mitogen-activated protein kinase 14/0.515
3hvcGG5Mitogen-activated protein kinase 14/0.512
3atzFMNProstaglandin F2a synthase/0.509
1bl6SB6Mitogen-activated protein kinase 14/0.508
4kip1R9Mitogen-activated protein kinase 14/0.505
1zz2B11Mitogen-activated protein kinase 14/0.503
2qd9LGFMitogen-activated protein kinase 14/0.503
3hllI45Mitogen-activated protein kinase 14/0.502
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.498
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.495
3il1B5DGlutamate receptor 2/0.495
3fl4FL4Mitogen-activated protein kinase 14/0.494
3mpt1GKMitogen-activated protein kinase 14/0.494
3gw9VNILanosterol 14-alpha-demethylase/0.491
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.491
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.489
2rg6287Mitogen-activated protein kinase 14/0.488
3s4qNK0Mitogen-activated protein kinase 14/0.487
4gk2L66Ephrin type-A receptor 32.7.10.10.487
1jpaANPEphrin type-B receptor 22.7.10.10.486
1bxoPP7Penicillopepsin-13.4.23.200.485
3u8w09JMitogen-activated protein kinase 14/0.485
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.484
2vnaNAPProstaglandin reductase 21.3.1.480.483
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.483
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.482
2rg5279Mitogen-activated protein kinase 14/0.482
3fkoFKOMitogen-activated protein kinase 14/0.482
3uxyNADShort-chain dehydrogenase/reductase SDR/0.482
3syiFADSulfide-quinone reductase/0.480
4g3jVNTLanosterol 14-alpha-demethylase/0.480
4gk3L87Ephrin type-A receptor 32.7.10.10.480
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.479
3gfeP37Mitogen-activated protein kinase 14/0.479
3p3zP3ZPutative cytochrome P450/0.479
1bsvNDPGDP-L-fucose synthase/0.478
1ouy094Mitogen-activated protein kinase 14/0.478
3mvl38PMitogen-activated protein kinase 14/0.478
3fmlFMLMitogen-activated protein kinase 14/0.477
5a3bAPRSIR2 family protein/0.477
2itpAEEEpidermal growth factor receptor2.7.10.10.476
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.476
3lqfNADGalactitol dehydrogenase/0.476
3roc29AMitogen-activated protein kinase 14/0.476
4kin1M8Mitogen-activated protein kinase 14/0.476
2itzIREEpidermal growth factor receptor2.7.10.10.475
2y6o1N1Ephrin type-A receptor 42.7.10.10.475
2qo9ANPEphrin type-A receptor 32.7.10.10.474
3fknFKNMitogen-activated protein kinase 14/0.474
3tk3CPZCytochrome P450 2B41.14.14.10.474
4dfrMTXDihydrofolate reductase1.5.1.30.473
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.472
3t2zFADSulfide-quinone reductase/0.472
1vjy460TGF-beta receptor type-12.7.11.300.471
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.471
2gfsPQBMitogen-activated protein kinase 14/0.471
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.471
3kpkFADSulfide-quinone reductase/0.471
4gk4L90Ephrin type-A receptor 32.7.10.10.471
1bygSTUTyrosine-protein kinase CSK/0.470
3fmmXI2Mitogen-activated protein kinase 14/0.470
4g2fC07Ephrin type-A receptor 32.7.10.10.470
4ryvZEAProtein LlR18A/0.470
4btkDTQTau-tubulin kinase 12.7.11.10.469
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.469
1kkq471Peroxisome proliferator-activated receptor alpha/0.468
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.468
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.468
1ywrLI9Mitogen-activated protein kinase 14/0.468
1zyjBI5Mitogen-activated protein kinase 14/0.468
2zbaZBATrichothecene 3-O-acetyltransferase/0.468
3l8p0CEAngiopoietin-1 receptor2.7.10.10.468
4nk92K5Fibroblast growth factor receptor 1/0.468
2ftoCB3Thymidylate synthase/0.467
2gjlFMNNitronate monooxygenase1.13.12.160.467
5c8yACPTubulin tyrosine ligase/0.467
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.466
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.465
2igoFADPyranose 2-oxidase/0.465
2wedPP6Penicillopepsin-13.4.23.200.465
3atyFMNProstaglandin F2a synthase/0.465
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.465
1fxsNAPGDP-L-fucose synthase/0.464
1k6tXN1Gag-Pol polyprotein3.4.23.160.464
1nhhANPDNA mismatch repair protein MutL/0.464
1ppjANYCytochrome b/0.464
2excJNKMitogen-activated protein kinase 102.7.11.240.464
2po7CHDFerrochelatase, mitochondrial4.99.1.10.464
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.464
2zb0GK3Mitogen-activated protein kinase 14/0.464
3ibdCPZCytochrome P450 2B61.14.130.464
3mvm39PMitogen-activated protein kinase 14/0.464
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.464
3uibSB2Putative mitogen-activated protein kinase/0.464
1ove358Mitogen-activated protein kinase 14/0.463
1qrpHH0Pepsin A-43.4.23.10.463
1yb5NAPQuinone oxidoreductase1.6.5.50.463
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.463
2j5xGSPADP-ribosylation factor 6/0.463
3l8xN4DMitogen-activated protein kinase 14/0.463
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.463
3vtdTKDVitamin D3 receptor/0.463
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.463
4ez8DHFThymidylate synthase2.1.1.450.463
1dnpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.462
1m17AQ4Epidermal growth factor receptor2.7.10.10.462
2itnANPEpidermal growth factor receptor2.7.10.10.462
2ok7FADFerredoxin--NADP reductase, apicoplast/0.462
2qnqQN3Gag-Pol polyprotein3.4.23.160.462
3b70NAPEnoyl reductase LovC10.462
3ggoNAIPrephenate dehydrogenase/0.462
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.461
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.461
3bbrBHYGlutamate receptor 2/0.461
3w33W19Epidermal growth factor receptor2.7.10.10.461
4r21STRCytochrome P450 family 17 polypeptide 2/0.461
4tuvCPZCytochrome P450 1191.140.461
4xj43ATCyclic GMP-AMP synthase/0.461
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.461
5dp2NAPCurF/0.461
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.460
1rneC60Renin3.4.23.150.460
2q7vFADThioredoxin reductase/0.460
3ocgOCGMitogen-activated protein kinase 14/0.460
3rn8RN8Glutamate receptor 2/0.460
4dbzNDPPutative ketoacyl reductase1.3.10.460
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.460
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.460
1n83CLRNuclear receptor ROR-alpha/0.459
1np7FADCryptochrome DASH/0.459
1zemNADXylitol dehydrogenase/0.459
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.459
3bv2P38Mitogen-activated protein kinase 14/0.459
3s1dZIRCytokinin dehydrogenase 11.5.99.120.459
4c02TAKActivin receptor type-12.7.11.300.459
4eh70OOMitogen-activated protein kinase 14/0.459
1tehNADAlcohol dehydrogenase class-31.1.1.10.458
1yw2PGJMitogen-activated protein kinase 14/0.458
2d29FADAcyl-CoA dehydrogenase/0.458
2wecPP5Penicillopepsin-13.4.23.200.458
3a1nNADNDP-sugar epimerase/0.458
3gu83GUDeath-associated protein kinase 12.7.11.10.458
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.458
4g7gVFVLanosterol 14-alpha-demethylase/0.458
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.458
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.458
1m13HYFNuclear receptor subfamily 1 group I member 2/0.457
1naiNADUDP-glucose 4-epimerase5.1.3.20.457
1ppm0P1Penicillopepsin-13.4.23.200.457
1xddAAYIntegrin alpha-L/0.457
2p5uNADUDP-glucose 4-epimerase/0.457
2zb3NDPProstaglandin reductase 21.3.1.480.457
3t14FADSulfide-quinone reductase/0.457
3t2kFADSulfide-quinone reductase/0.457
3ttiKBIMitogen-activated protein kinase 102.7.11.240.457
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.457
4f650S9Fibroblast growth factor receptor 1/0.457
4gh5NADShort-chain dehydrogenase/reductase SDR/0.457
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.457
4ia7BIVVitamin D3 receptor A/0.457
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
2gtnLIEMitogen-activated protein kinase 14/0.456
2qoqANPEphrin type-A receptor 32.7.10.10.456
2vn0TDZCytochrome P450 2C8/0.456
3c1y2BADNA integrity scanning protein DisA/0.456
3gfbNADL-threonine 3-dehydrogenase/0.456
3h3sH15Collagen type IV alpha-3-binding protein/0.456
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.456
3itzP66Mitogen-activated protein kinase 14/0.456
3sz0FADSulfide-quinone reductase/0.456
4e2bFMNDehydrogenase/0.456
4kb81QOCasein kinase I isoform delta2.7.11.10.456
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.456
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.456
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.455
1f4fTP3Thymidylate synthase/0.454
1mp0NADAlcohol dehydrogenase class-31.1.1.10.454
1u3dFADCryptochrome-1/0.454
1y0s331Peroxisome proliferator-activated receptor delta/0.454
2henADPEphrin type-B receptor 22.7.10.10.454
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.454
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.454
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.454
4mv8ACPBiotin carboxylase6.3.4.140.454
4r20AERCytochrome P450 family 17 polypeptide 2/0.454
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.454
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1k6pXN3Gag-Pol polyprotein3.4.23.160.453
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1m7qDQOMitogen-activated protein kinase 14/0.453
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.453
2d8aNADL-threonine 3-dehydrogenase/0.453
2ittAEEEpidermal growth factor receptor2.7.10.10.453
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.453
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.453
3gy0NAPNAD(P)-dependent oxidoreductase/0.453
3l63CAMCamphor 5-monooxygenase1.14.15.10.453
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.453
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.453
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.453
4ia1BIVVitamin D3 receptor A/0.453
4l4dCAMCamphor 5-monooxygenase1.14.15.10.453
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.453
1d4dFADFumarate reductase flavoprotein subunit1.3.5.40.452
1rfvADPPyridoxal kinase2.7.1.350.452
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.452
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.452
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.452
3tdaPN0Cytochrome P450 2D6/0.452
3zc3NAPFerredoxin--NADP reductase1.18.1.20.452
3zkpERBErythromycin C-12 hydroxylase1.14.13.1540.452
4jr3KJREpidermal growth factor receptor2.7.10.10.452
4kl9NDPDihydrofolate reductase1.5.1.30.452
4xgxADPFAD:protein FMN transferase/0.452
5a3cNADSIR2 family protein/0.452
5jlaNADPutative short-chain dehydrogenase/reductase/0.452
1fm4DXCMajor pollen allergen Bet v 1-L/0.451
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.451
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.451
2q3kMUWGag-Pol polyprotein/0.451
2wdzNADGalactitol dehydrogenase/0.451
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.451
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.451
3a4vNADNDP-sugar epimerase/0.451
3bgcLJHGag-Pol polyprotein3.4.23.160.451
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.451
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.451
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.451
4ia3BIVVitamin D3 receptor A/0.451
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.451
4o701QKBromodomain-containing protein 4/0.451
4q1w017Gag-Pol polyprotein3.4.23.160.451
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.451
5ijzNAPNADP-specific glutamate dehydrogenase1.4.1.40.451
1fy7COAHistone acetyltransferase ESA1/0.450
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1hk5T44Serum albumin/0.450
1hncGDNGlutathione S-transferase Mu 22.5.1.180.450
1mg5NAIAlcohol dehydrogenase1.1.1.10.450
2ejvNADL-threonine 3-dehydrogenase/0.450
2q5g1FAPeroxisome proliferator-activated receptor delta/0.450
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.450
2zazGK1Mitogen-activated protein kinase 14/0.450
3drcMTXDihydrofolate reductase1.5.1.30.450
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.450
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.450
3uyt0CKCasein kinase I isoform delta2.7.11.10.450
4a6bQG8Gag-Pol polyprotein3.4.23.160.450
4bj9UHBTankyrase-22.4.2.300.450
4e2dFMNDehydrogenase/0.450
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.450
4nfn2KCTau-tubulin kinase 12.7.11.10.450
4y8wSTRSteroid 21-hydroxylase/0.450
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.450
1db1VDXVitamin D3 receptor/0.449
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1k7l544Peroxisome proliferator-activated receptor alpha/0.449
1qvnFRIInterleukin-2/0.449
1xe55FEPlasmepsin-23.4.23.390.449
2vd5BI8Myotonin-protein kinase2.7.11.10.449
3b6zCO7Enoyl reductase LovC10.449
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
3nbvANPKetohexokinase/0.449
3vyeVYERenin3.4.23.150.449
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.449
4dfg0JVGag-Pol polyprotein3.4.23.160.449
4l4xNDPAmphI/0.449
5k2bZMAAdenosine receptor A2a/0.449
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.448
1iwiCAMCamphor 5-monooxygenase1.14.15.10.448
1xkkFMMEpidermal growth factor receptor2.7.10.10.448
2oapANPType II secretion system protein (GspE-2)/0.448
2ou2ACOHistone acetyltransferase KAT5/0.448
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.448
3a3gDLZLumazine protein/0.448
3e5rNADGlyceraldehyde-3-phosphate dehydrogenase 1, cytosolic1.2.1.120.448
3gggNADPrephenate dehydrogenase/0.448
3i7eDJRGag-Pol polyprotein/0.448
3mdvCL6Cholesterol 24-hydroxylase/0.448
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.448
4ewqMWLMitogen-activated protein kinase 14/0.448
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.448
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.448
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.448
4jrvKJVEpidermal growth factor receptor2.7.10.10.448
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.448
4rf2NAPNADPH dependent R-specific alcohol dehydrogenase/0.448
5lc1NADL-threonine 3-dehydrogenase/0.448
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.447
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.447
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.447
2npnSAMPutative cobalamin synthesis related protein/0.447
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.447
3el9DR7Gag-Pol polyprotein3.4.23.160.447
3isjA8DPantothenate synthetase6.3.2.10.447
3toh079Gag-Pol polyprotein2.7.7.490.447
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.447
4enhFVXCholesterol 24-hydroxylase/0.447
4yaiNAIC alpha-dehydrogenase/0.447
1nvtNAPShikimate dehydrogenase (NADP(+))/0.446
1qiqACCIsopenicillin N synthase1.21.3.10.446
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.446
2jn3JN3Fatty acid-binding protein, liver/0.446
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.446
2y99NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.446
3ajrNADNDP-sugar epimerase/0.446
3hx4ANPCalmodulin-domain protein kinase 1/0.446
3rj9NADAlcohol dehydrogenase1.1.1.10.446
4q71FADBifunctional protein PutA/0.446
4rujVDXVitamin D3 receptor A/0.446
4yagNAIC alpha-dehydrogenase/0.446
1hwzNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.445
1ie8KH1Vitamin D3 receptor/0.445
1k6cMK1Gag-Pol polyprotein3.4.23.160.445
1pdhFASp-hydroxybenzoate hydroxylase/0.445
1qjfACSIsopenicillin N synthase1.21.3.10.445
1vikBAYGag-Pol polyprotein/0.445
2gtmLIDMitogen-activated protein kinase 14/0.445
2hcdBIVVitamin D3 receptor A/0.445
2vynNADGlyceraldehyde-3-phosphate dehydrogenase A/0.445
2yn8STUEphrin type-B receptor 42.7.10.10.445
3ey9TDPPyruvate dehydrogenase [ubiquinone]1.2.5.10.445
3gc9B45Mitogen-activated protein kinase 112.7.11.240.445
3iocA5DPantothenate synthetase6.3.2.10.445
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.445
3rucNADUDP-N-acetylglucosamine 4-epimerase/0.445
3sp9IL2Peroxisome proliferator-activated receptor delta/0.445
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.445
3tqhNDPQuinone oxidoreductase/0.445
3vrwYS5Vitamin D3 receptor/0.445
3vydVYDRenin3.4.23.150.445
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.445
4nmbFADBifunctional protein PutA/0.445
4v2gITCTetracycline repressor protein class D/0.445
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.445
1bxqPP8Penicillopepsin-13.4.23.200.444
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.444
1mjaCOAHistone acetyltransferase ESA1/0.444
1pr9NAPL-xylulose reductase1.1.1.100.444
1qo8FADFumarate reductase flavoprotein subunit/0.444
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.444
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
1yqj6NPMitogen-activated protein kinase 14/0.444
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.444
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.444
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.444
2q2qNADBeta-D-hydroxybutyrate dehydrogenase/0.444
3d7zGK5Mitogen-activated protein kinase 14/0.444
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.444
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.444
3ha85JZMitogen-activated protein kinase 14/0.444
3hp552PMitogen-activated protein kinase 14/0.444
3tvuB37Acetyl-CoA carboxylase/0.444
3w32W32Epidermal growth factor receptor2.7.10.10.444
3w4yFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.444
3zsh469Mitogen-activated protein kinase 14/0.444
4b1rITCTetracycline repressor protein class D/0.444
4jq7KJQEpidermal growth factor receptor2.7.10.10.444
4ki8ADP60 kDa chaperonin/0.444
4nieNBHNuclear receptor ROR-gamma/0.444
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.444
1a72PADAlcohol dehydrogenase E chain1.1.1.10.443
1cf3FADGlucose oxidase1.1.3.40.443
1gqtACPRibokinase/0.443
1jioDEB6-deoxyerythronolide B hydroxylase/0.443
1ma0NADAlcohol dehydrogenase class-31.1.1.10.443
1nzdUPGDNA beta-glucosyltransferase/0.443
1tkgSSAThreonine--tRNA ligase6.1.1.30.443
2fhnBNIAvidin-related protein 4/5/0.443
2ituITQEpidermal growth factor receptor2.7.10.10.443
2qo7ANPEphrin type-A receptor 32.7.10.10.443
2vwhNAPGlucose 1-dehydrogenase/0.443
2xa4AZ5Tyrosine-protein kinase JAK2/0.443
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.443
3hmm855TGF-beta receptor type-12.7.11.300.443
3ieuGDPGTPase Era/0.443
3p99LNPLanosterol 14-alpha-demethylase/0.443
3slkNDPPolyketide synthase extender module 2/0.443
3w6hAZMCarbonic anhydrase 14.2.1.10.443
4ambDUDPutative glycosyl transferase/0.443
4bb432WEphrin type-B receptor 42.7.10.10.443
4ejmNAPPutative zinc-binding dehydrogenase/0.443
4kbc1QJCasein kinase I isoform delta2.7.11.10.443
4nka2K7Fibroblast growth factor receptor 1/0.443
4oaeCLMUncharacterized protein/0.443
4x5gFOLDihydrofolate reductase1.5.1.30.443
1ae1NAPTropinone reductase 1/0.442
1fmlRTLRetinol dehydratase/0.442
1g6kNADGlucose 1-dehydrogenase1.1.1.470.442
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.442
1knrFADL-aspartate oxidase1.4.3.160.442
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.442
1mvsDTMDihydrofolate reductase1.5.1.30.442
1psa0ZLPepsin A3.4.23.10.442
1s0xC3SNuclear receptor ROR-alpha/0.442
2fy4COACholine O-acetyltransferase2.3.1.60.442
2j09FADDeoxyribodipyrimidine photo-lyase4.1.99.30.442
2o7pNAPRiboflavin biosynthesis protein RibD/0.442
3d8bADPFidgetin-like protein 13.6.40.442
3e2sFADBifunctional protein PutA1.5.5.20.442
3idsNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.442
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.442
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.442
4mihFADPyranose 2-oxidase1.1.3.100.442
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.442
4nc3ERM5-hydroxytryptamine receptor 2B/0.442
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.442
5e8wSTUTGF-beta receptor type-12.7.11.300.442
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.442
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.441
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.441
2a87FADThioredoxin reductase1.8.1.90.441
2dfvNADL-threonine 3-dehydrogenase/0.441
2he5NDPAldo-keto reductase family 1 member C211.1.10.441
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.441
2qboCAMCamphor 5-monooxygenase1.14.15.10.441
2v6gNAP3-oxo-Delta(4,5)-steroid 5-beta-reductase/0.441
2vbdV10Isopenicillin N synthase1.21.3.10.441
2vwz7X6Ephrin type-B receptor 42.7.10.10.441
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.441
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.441
2xx91NFGlutamate receptor 2/0.441
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.441
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.441
3fmjFMJMitogen-activated protein kinase 14/0.441
3ivgFG5Pantothenate synthetase6.3.2.10.441
3l0lHC3Nuclear receptor ROR-gamma/0.441
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.441
4cdmFADDeoxyribodipyrimidine photolyase/0.441
4e5yNDPGDP-L-fucose synthase1.1.1.2710.441
4eh60ONMitogen-activated protein kinase 14/0.441
4fod0UVALK tyrosine kinase receptor2.7.10.10.441
4ia2BIVVitamin D3 receptor A/0.441
4qe6JN3Bile acid receptor/0.441
1e3eNAIAlcohol dehydrogenase 41.1.1.10.440
1gypNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.440
1ipeNDPTropinone reductase 21.1.1.2360.440
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
2a94AP0L-lactate dehydrogenase1.1.1.270.440
2b7aIZATyrosine-protein kinase JAK2/0.440
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.440
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
2i0aMUIProtease/0.440
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.440
2o0uC0MMitogen-activated protein kinase 102.7.11.240.440
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.440
2vtbFADCryptochrome DASH, chloroplastic/mitochondrial/0.440
2vx07X7Ephrin type-B receptor 42.7.10.10.440
2vx17X8Ephrin type-B receptor 42.7.10.10.440
3iaeD7KBenzaldehyde lyase/0.440
3kytHC2Nuclear receptor ROR-gamma/0.440
3oibFDAPutative acyl-CoA dehydrogenase/0.440
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.440
3vrtYS2Vitamin D3 receptor/0.440
3w5p4OAVitamin D3 receptor/0.440
3zeiAWHO-acetylserine sulfhydrylase/0.440
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.440
4dymIYZActivin receptor type-12.7.11.300.440
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.440
4fv9E71Mitogen-activated protein kinase 12.7.11.240.440
4g95OAGDihydrofolate reductase1.5.1.30.440
4i231C9Epidermal growth factor receptor2.7.10.10.440
4i8zG08Gag-Pol polyprotein3.4.23.160.440
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.440
5eccNAPDehydrofolate reductase type I/0.440
5ifiPRXAcetyl-coenzyme A synthetase/0.440
4djhJDCKappa-type opioid receptor/0.440