sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3fl9 | TOP | Dihydrofolate reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3fl9 | TOP | Dihydrofolate reductase | / | 1.000 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.618 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.604 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.591 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.585 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.563 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.558 | |
| 4elh | 53I | Dihydrofolate reductase | / | 0.558 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.556 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.555 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.554 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.554 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.549 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.544 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.542 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.541 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.540 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.532 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.530 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.523 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.522 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.522 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.520 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.519 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.518 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.518 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.518 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.517 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.517 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.515 | |
| 4qi9 | MTX | Dihydrofolate reductase | / | 0.514 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.503 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.502 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.497 | |
| 1rg7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.495 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.494 | |
| 5hi6 | MTX | Dihydrofolate reductase | / | 0.492 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.491 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.486 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.484 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.484 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.482 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.482 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.481 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.481 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.480 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.479 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.479 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.479 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.478 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.478 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.478 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.478 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.477 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.476 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.476 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.475 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.475 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.474 | |
| 2d0k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.474 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.473 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.473 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.473 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.473 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.473 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.472 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.472 | |
| 3m08 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.471 | |
| 1efv | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.470 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.470 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.469 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.468 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.468 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.468 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.467 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.467 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.467 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 3nxe | 2NC | Protease | / | 0.467 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.467 | |
| 4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.467 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.467 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.466 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.466 | |
| 3dej | RXC | Caspase-3 | 3.4.22.56 | 0.466 | |
| 4o4f | ATP | Kinase | / | 0.466 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.466 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.466 | |
| 1zdw | FLV | Prenyltransferase | / | 0.465 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.465 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.465 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.464 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.464 | |
| 1k2c | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 1ppj | ANY | Cytochrome b | / | 0.464 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.464 | |
| 3qly | 55V | Uncharacterized protein | / | 0.464 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.464 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.464 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.464 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.463 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.463 | |
| 3hwr | NDP | 2-dehydropantoate 2-reductase | / | 0.463 | |
| 3zux | TCH | Transporter | / | 0.463 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.463 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.463 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.463 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.462 | |
| 1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.462 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.462 | |
| 3w0n | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.462 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.462 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 4iae | 1DX | Alr2278 protein | / | 0.462 | |
| 1osv | CHC | Bile acid receptor | / | 0.461 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.461 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.461 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.461 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.461 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.460 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.460 | |
| 4ki8 | ADP | 60 kDa chaperonin | / | 0.460 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.459 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.459 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.459 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.459 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.459 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.459 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.459 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.458 | |
| 3el9 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 3f47 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.458 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.458 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.458 | |
| 4o0s | ADN | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 4xx0 | COA | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | 6.2.1.4 | 0.458 | |
| 5a3b | APR | SIR2 family protein | / | 0.458 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1fff | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.457 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.457 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.457 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.457 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.457 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.457 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.457 | |
| 4idt | T28 | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.457 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.457 | |
| 2h3w | COA | Carnitine O-acetyltransferase | 2.3.1.7 | 0.456 | |
| 2xye | CXG | Gag-Pol polyprotein | / | 0.456 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.456 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.456 | |
| 3gob | HXX | DdmC | / | 0.456 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.456 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.456 | |
| 4bbh | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.456 | |
| 4o7u | THF | Thymidylate synthase | / | 0.456 | |
| 4ye3 | G04 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 5a3c | NAD | SIR2 family protein | / | 0.456 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.455 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.455 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.455 | |
| 3jy0 | LYG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.455 | |
| 3w1f | 1O5 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.455 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.455 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.455 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.454 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1rl8 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.454 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.454 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.454 | |
| 3el5 | 1UN | Gag-Pol polyprotein | / | 0.454 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.454 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.454 | |
| 3qcx | 3Q2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.454 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.454 | |
| 4fog | C2F | Thymidylate synthase ThyA | / | 0.454 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.454 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.454 | |
| 1fml | RTL | Retinol dehydratase | / | 0.453 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.453 | |
| 1gqt | ACP | Ribokinase | / | 0.453 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.453 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 3dat | MTX | Dihydrofolate reductase | / | 0.453 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.453 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.453 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.453 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.453 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.453 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.453 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.453 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.453 | |
| 1daw | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 1e0a | GNP | Cell division control protein 42 homolog | / | 0.452 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.452 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.452 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.452 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.452 | |
| 2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.452 | |
| 2bja | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.452 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.452 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.452 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.452 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3mb7 | 14I | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 3ttp | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3zuy | TCH | Transporter | / | 0.452 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.452 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.452 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.452 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.452 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.452 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.452 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.452 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.452 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.452 | |
| 5c41 | ACP | Ribokinase | / | 0.452 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.452 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.451 | |
| 2dr3 | ADP | UPF0273 protein PH0284 | / | 0.451 | |
| 2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.451 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.451 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.451 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.451 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.451 | |
| 3up4 | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.451 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.451 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.451 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.451 | |
| 1an5 | CB3 | Thymidylate synthase | / | 0.450 | |
| 1c6y | MK1 | Protease | / | 0.450 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.450 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.450 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.450 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.450 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.450 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.450 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.450 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.450 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.450 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 3haz | FAD | Bifunctional protein PutA | / | 0.450 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.450 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.450 | |
| 3oro | AGS | Serine/threonine protein kinase | / | 0.450 | |
| 3sh0 | SAX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.450 | |
| 3ucb | 017 | Gag-Pol polyprotein | / | 0.450 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.450 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.450 | |
| 4wbb | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.450 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 1exa | 394 | Retinoic acid receptor gamma | / | 0.449 | |
| 1fd0 | 254 | Retinoic acid receptor gamma | / | 0.449 | |
| 1hvi | A77 | Protease | / | 0.449 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.449 | |
| 1m2p | HNA | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.449 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2pvy | ACP | Fibroblast growth factor receptor 2 | / | 0.449 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.449 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.449 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3b20 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.449 | |
| 3srq | Q19 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4b4d | FAD | Ferredoxin-NADP reductase | / | 0.449 | |
| 4e2b | FMN | Dehydrogenase | / | 0.449 | |
| 4e2d | FMN | Dehydrogenase | / | 0.449 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.449 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 1sqv | UHD | Cytochrome b | / | 0.448 | |
| 2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.448 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.448 | |
| 2bpw | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 2gek | GDP | Phosphatidyl-myo-inositol mannosyltransferase | 2.4.1.57 | 0.448 | |
| 2idw | 017 | Protease | / | 0.448 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.448 | |
| 3fy9 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.448 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.448 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.448 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.448 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.448 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.448 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.448 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.448 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.448 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1ghe | ACO | Acetyltransferase | 2.3.1 | 0.447 | |
| 1k2b | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.447 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.447 | |
| 2fgj | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.447 | |
| 2nnp | ROC | Protease | / | 0.447 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 3aba | FLI | Cytochrome P450 | / | 0.447 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.447 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.447 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.447 | |
| 4v12 | POG | MaoC like domain protein | / | 0.447 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.447 | |
| 5a27 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.446 | |
| 1hvs | A77 | Gag-Pol polyprotein | / | 0.446 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.446 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.446 | |
| 2g27 | 4LG | Renin | 3.4.23.15 | 0.446 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.446 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.446 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.446 | |
| 3el1 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.446 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.446 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.446 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.446 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.446 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.445 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1ci7 | CB3 | Thymidylate synthase | 2.1.1.45 | 0.445 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.445 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.445 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.445 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.445 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.445 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.445 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.445 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.445 | |
| 3ekw | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3fyw | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.445 | |
| 4a32 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 4bl5 | GFB | GDP-L-fucose synthase | 1.1.1.271 | 0.445 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.445 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.445 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 1ddu | CB3 | Thymidylate synthase | / | 0.444 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1pnv | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.444 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.444 | |
| 2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.444 | |
| 2owu | SAH | Diphthine synthase | / | 0.444 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2vu3 | LZE | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2yyy | NAP | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.59 | 0.444 | |
| 3dcr | KVS | Protease | / | 0.444 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.444 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.444 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.444 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.444 | |
| 4eu5 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.444 | |
| 4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.444 | |
| 4l8u | 9AZ | Serum albumin | / | 0.444 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.444 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.443 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.443 | |
| 1q6s | 214 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.443 | |
| 1rye | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.443 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 2aqu | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2ejz | SAH | Diphthine synthase | / | 0.443 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.443 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.443 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.443 | |
| 3fi3 | JK2 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.443 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.443 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.443 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.443 | |
| 4l9k | EHF | Serum albumin | / | 0.443 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.443 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.443 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.443 | |
| 1d4h | BEH | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.442 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.442 | |
| 2b1p | AIZ | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.442 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.442 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 3ce3 | 1FN | Hepatocyte growth factor receptor | 2.7.10.1 | 0.442 | |
| 3cge | NDP | Coenzyme A disulfide reductase | / | 0.442 | |
| 3dk1 | G05 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.442 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.442 | |
| 3pxk | PXK | Focal adhesion kinase 1 | 2.7.10.2 | 0.442 | |
| 3u9e | COA | Lmo1369 protein | / | 0.442 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.442 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 3w2w | ATP | CRISPR system Cmr subunit Cmr2 | / | 0.442 | |
| 3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.442 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.442 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.442 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 1dif | A85 | Gag-Pol polyprotein | / | 0.441 | |
| 1ff0 | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.441 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.441 | |
| 1khr | VIR | Streptogramin A acetyltransferase | 2.3.1 | 0.441 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.441 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.441 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.441 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.441 | |
| 2hc0 | AB2 | Protease | / | 0.441 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.441 | |
| 2ijm | ADP | Focal adhesion kinase 1 | 2.7.10.2 | 0.441 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.441 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.441 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.441 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.441 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3ggx | GGX | Gag-Pol polyprotein | / | 0.441 | |
| 3i2l | 2NC | Protease | / | 0.441 | |
| 3kfs | 3TL | Gag-Pol polyprotein | / | 0.441 | |
| 3pwr | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3qrm | NK7 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3r8v | Z62 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 3uk6 | ADP | RuvB-like 2 | 3.6.4.12 | 0.441 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4b14 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.441 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.441 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.441 | |
| 4py6 | R78 | Bromodomain protein, putative | / | 0.441 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.441 | |
| 5amn | DTQ | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.441 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.441 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.441 | |
| 1dd6 | MCI | Metallo-beta-lactamase type 2 | / | 0.440 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1xdk | REA | Retinoic acid receptor beta | / | 0.440 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.440 | |
| 2qak | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.440 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.440 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.440 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.440 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.440 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 4h3q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 4nxw | ADP | Mitochondrial dynamics protein MID51 | / | 0.440 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.440 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.440 | |
| 5awm | ANP | Stress-activated protein kinase JNK | 2.7.11.24 | 0.440 | |
| 5doz | NDP | JamJ | / | 0.440 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.440 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.440 |