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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3fgoCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.8

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3fgoCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.81.000
4bewCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.888
3fpbCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.600
2eauCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.460
3m9vTYDFAD-dependent oxidoreductase/0.452
3opdHIEHeat shock protein 83/0.447
4kcfAKMFAD-dependent oxidoreductase/0.447
2j0dERYCytochrome P450 3A4/0.443
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440