sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3f8r | NAP | NADH oxidase/thioredoxin reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 1.000 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.612 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.603 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.476 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.452 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.449 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.448 | |
| 4ccr | FAD | Thioredoxin reductase | / | 0.444 |