Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3ewrAPRReplicase polyprotein 1a3.4.22

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3ewrAPRReplicase polyprotein 1a3.4.221.000
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.517
5fsxADPUncharacterized protein/0.516
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.514
5cb3APRO-acetyl-ADP-ribose deacetylase/0.481
2f98NGVAklanonic acid methyl ester cyclase AcmA5.5.1.230.462
5cb5APRO-acetyl-ADP-ribose deacetylase/0.454
3siiA1RUncharacterized protein/0.451
3w2eNADNADH-cytochrome b5 reductase 31.6.2.20.449
3sigAR6Uncharacterized protein/0.448
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.445