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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3ew2BTNHypothetical conserved protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3ew2BTNHypothetical conserved protein/1.000
4z28BTNHoefavidin/0.578
2rtdBTNStreptavidin/0.496
2izhBTNStreptavidin/0.487
1mk5BTNStreptavidin/0.485
2izgBTNStreptavidin/0.482
2rteBTNStreptavidin/0.480
2izlIMIStreptavidin/0.475
4gdaBTNStreptavidin/0.473
2rtnIMIStreptavidin/0.467
1swtBTNStreptavidin/0.466
2rtgBTNStreptavidin/0.466
4dneDTBStreptavidin/0.466
2rtoIMIStreptavidin/0.465
4g1z0VPVitamin D3 receptor A/0.465
2izfBTNStreptavidin/0.464
2rtfBTNStreptavidin/0.462
3ry2BTNStreptavidin/0.460
4ure1PSCyclohexanol dehydrogenase/0.460
1ppjANYCytochrome b/0.456
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1sreHABStreptavidin/0.454
1i9hBNIStreptavidin/0.453
1luqBTNStreptavidin/0.453
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.451
1nqmBTNStreptavidin/0.448
2aviBTNAvidin/0.446
2rtrIMIStreptavidin/0.446
2fhnBNIAvidin-related protein 4/5/0.445
5cb3APRO-acetyl-ADP-ribose deacetylase/0.445
1stpBTNStreptavidin/0.443
1sriDMBStreptavidin/0.442
5g53NECAdenosine receptor A2a/0.441
1lcwSHMStreptavidin/0.440
4bx7B4FStreptavidin/0.440