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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3evaSAHGenome polyprotein2.1.1.56

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3evaSAHGenome polyprotein2.1.1.561.000
3evbSAHGenome polyprotein2.1.1.560.626
3p8zSAHGenome polyprotein2.1.1.560.591
3evcSAHGenome polyprotein2.1.1.560.548
5cuqNSCGenome polyprotein/0.545
2px2SAHGenome polyprotein2.7.7.480.523
2p3qSAHGenome polyprotein/0.521
1l9kSAHGenome polyprotein2.7.7.480.520
2oxtSAMGenome polyprotein/0.519
3ns2PYVAbscisic acid receptor PYL2/0.508
2p1dSAHGenome polyprotein2.7.7.480.502
4ctkSAMGenome polyprotein/0.502
2pxaSAHGenome polyprotein2.7.7.480.501
3nr4PYVAbscisic acid receptor PYL2/0.498
1r6aSAHGenome polyprotein2.7.7.480.497
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.494
3elySAHMethyltransferase/0.493
5jjrSAHGenome polyprotein/0.492
3ibqATPPyridoxal kinase/0.488
2z7gEH9Adenosine deaminase3.5.4.40.487
2p41SAHGenome polyprotein/0.485
2px5SAHGenome polyprotein2.7.7.480.483
4g090VDHistidinol dehydrogenase/0.482
1ci7UMPThymidylate synthase2.1.1.450.481
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.481
5dtoSAHGenome polyprotein/0.481
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.480
3gwfFADCyclohexanone monooxygenase/0.480
3p97SAMGenome polyprotein2.1.1.560.478
1uy7PU4Heat shock protein HSP 90-alpha/0.477
2ojg19AMitogen-activated protein kinase 12.7.11.240.476
2itpAEEEpidermal growth factor receptor2.7.10.10.475
2wo7ASVIsopenicillin N synthase1.21.3.10.475
4hnc0UTMandelate racemase/0.475
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.475
4nmcFADBifunctional protein PutA/0.473
3zhrTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.472
1fw0KAIGlutamate receptor 2/0.471
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.470
3p8z36AGenome polyprotein2.1.1.560.470
2wa2SAMGenome polyprotein/0.469
3mpt1GKMitogen-activated protein kinase 14/0.469
1jpaANPEphrin type-B receptor 22.7.10.10.468
2p5uNADUDP-glucose 4-epimerase/0.468
3b9lAZZSerum albumin/0.468
3dhbC6LN-acyl homoserine lactonase AiiA3.1.1.810.468
4k6mSAHGenome polyprotein/0.468
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.467
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
2bfaCB3Pteridine reductase 11.5.1.330.467
3fp0FP015-O-acetyltransferase/0.467
3my5RFZCyclin-dependent kinase 22.7.11.220.467
3pxkPXKFocal adhesion kinase 12.7.10.20.467
4otyLURProstaglandin G/H synthase 21.14.99.10.467
3q3cNADNAD-dependent L-serine dehydrogenase/0.466
3uqdATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.466
3a6rFMNFMN-binding protein/0.465
3nmpPYVAbscisic acid receptor PYL2/0.465
4u0oMTALipoyl synthase 2/0.465
1e92HBIPteridine reductase 11.5.1.330.464
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.464
2bkzSBCCyclin-dependent kinase 22.7.11.220.463
2bwg5GPGMP reductase 1/0.463
2fwzH71Heat shock protein HSP 90-alpha/0.463
2ittAEEEpidermal growth factor receptor2.7.10.10.463
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.463
3hkoANPCalcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands/0.463
1h1s4SPCyclin-dependent kinase 22.7.11.220.462
2itwITQEpidermal growth factor receptor2.7.10.10.462
2izuP01Casein kinase I isoform gamma-32.7.11.10.462
3njoP2MAbscisic acid receptor PYR1/0.462
3roy22ZCyclin-dependent kinase 22.7.11.220.462
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.462
4ctjSAMGenome polyprotein/0.462
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.462
4ho8THMGlucose-1-phosphate thymidylyltransferase/0.462
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.462
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.461
1dxyNADD-2-hydroxyisocaproate dehydrogenase1.1.10.461
1lhuESTSex hormone-binding globulin/0.461
1v0oINRCell division control protein 2 homolog2.7.11.220.461
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.461
2vkeTACTetracycline repressor protein class D/0.461
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.461
3a14NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.461
3bhrTHGThymidylate synthase/0.461
3nmnPYVAbscisic acid receptor PYL1/0.461
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.461
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.461
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.461
4fogC2FThymidylate synthase ThyA/0.461
1bsvNDPGDP-L-fucose synthase/0.460
1uy9PU6Heat shock protein HSP 90-alpha/0.460
2cduFADNADH oxidase/0.460
2izt23DCasein kinase I isoform gamma-32.7.11.10.460
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.460
3otwCOAPhosphopantetheine adenylyltransferase/0.460
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.460
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
1r2jFADFkbI/0.459
2qocANPEphrin type-A receptor 32.7.10.10.459
2w6zL21Biotin carboxylase6.3.4.140.459
3fhxPLPPyridoxal kinase2.7.1.350.459
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.459
3g2hKOTGlycogen phosphorylase, muscle form2.4.1.10.459
3kdiA8SAbscisic acid receptor PYL2/0.459
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.459
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.459
5e8wSTUTGF-beta receptor type-12.7.11.300.459
1f3eDPZQueuine tRNA-ribosyltransferase2.4.2.290.458
1pxxDIFProstaglandin G/H synthase 21.14.99.10.458
1wxyFRKAdenosine deaminase3.5.4.40.458
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.458
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.458
2wihP48Cyclin-dependent kinase 22.7.11.220.458
3c35KAIGlutamate receptor ionotropic, kainate 1/0.458
3ddqRRCCyclin-dependent kinase 22.7.11.220.458
3dogNNNCyclin-dependent kinase 22.7.11.220.458
4c02TAKActivin receptor type-12.7.11.300.458
5jjsSAHGenome polyprotein/0.458
1cdeGARPhosphoribosylglycinamide formyltransferase/0.457
1ihxSNDGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.457
2ds11CDCyclin-dependent kinase 22.7.11.220.457
2vn0TDZCytochrome P450 2C8/0.457
3mtfA3FActivin receptor type-12.7.11.300.457
3oafOAGDihydrofolate reductase1.5.1.30.457
4b99R4LMitogen-activated protein kinase 72.7.11.240.457
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.456
1qxlFR8Adenosine deaminase3.5.4.40.456
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.456
2jlaTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.456
3eluSAMMethyltransferase/0.456
3q9wEMOCasein kinase II subunit alpha2.7.11.10.456
3uibSB2Putative mitogen-activated protein kinase/0.456
3w9rA8SAbscisic acid receptor PYL9/0.456
4qnaX11Serine/threonine-protein kinase 242.7.11.10.456
1h63FMNPentaerythritol tetranitrate reductase/0.455
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.455
2v59LZKBiotin carboxylase6.3.4.140.455
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.455
1h65GDPTranslocase of chloroplast 343.6.50.454
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.454
4bb432WEphrin type-B receptor 42.7.10.10.454
5fs9FADApoptosis-inducing factor 1, mitochondrial1.1.10.454
1bwsNDPGDP-L-fucose synthase/0.453
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.453
1jm6ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.453
1krhFADBenzoate 1,2-dioxygenase electron transfer component1.18.1.30.453
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.453
1v79FR7Adenosine deaminase3.5.4.40.453
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.453
2w6nOA2Biotin carboxylase6.3.4.140.453
3ed1GA3Gibberellin receptor GID1/0.453
3eldSFGMethyltransferase/0.453
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.453
4fhbFOLDihydrofolate reductase1.5.1.30.453
4fob0USALK tyrosine kinase receptor2.7.10.10.453
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
1csnATPCasein kinase I homolog 12.7.11.10.452
1e7qNAPGDP-L-fucose synthase/0.452
1h51FMNPentaerythritol tetranitrate reductase/0.452
1n3rGTPGTP cyclohydrolase 13.5.4.160.452
1oirHDYCyclin-dependent kinase 22.7.11.220.452
1u3cFADCryptochrome-1/0.452
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.452
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.452
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.452
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
3nj0PYVAbscisic acid receptor PYL2/0.452
4cd0AWJALK tyrosine kinase receptor2.7.10.10.452
4l4dCAMCamphor 5-monooxygenase1.14.15.10.452
4n57ADPAPH(2'')-Id/0.452
4ogrADNCyclin-dependent kinase 92.7.11.220.452
4u7wNDPMxaA/0.452
4zs2FLUAlpha-ketoglutarate-dependent dioxygenase FTO/0.452
1e9hINRCyclin-dependent kinase 22.7.11.220.451
1o5rFR9Adenosine deaminase3.5.4.40.451
2bgjFADNADPH:ferredoxin reductase/0.451
2zjwREFCasein kinase II subunit alpha2.7.11.10.451
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.451
3kb6NADD-lactate dehydrogenase/0.451
3ujlA8SAbscisic acid receptor PYL2/0.451
3vg9ZMAAdenosine receptor A2a/0.451
3zdu38RCyclin-dependent kinase-like 32.7.11.220.451
4hjfC2EGGDEF family protein/0.451
4rw4494Gag-Pol polyprotein2.7.7.490.451
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.450
1l8qADPChromosomal replication initiator protein DnaA/0.450
2x1nX1NCyclin-dependent kinase 22.7.11.220.450
3a7hATPSerine/threonine-protein kinase 242.7.11.10.450
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
3inwJZBHeat shock protein HSP 90-alpha/0.450
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.450
3r1qX75Cyclin-dependent kinase 22.7.11.220.450
3wv9FEGHmd co-occurring protein HcgE/0.450
4cfnJYMCyclin-dependent kinase 22.7.11.220.450
4iteTEYVitamin D3 receptor/0.450
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.450
4yuqKS1Calmodulin-like domain protein kinase/0.450
5eccNAPDehydrofolate reductase type I/0.450
5ej9TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.450
1culFOKAdenylate cyclase type 2/0.449
1culFOKAdenylate cyclase type 5/0.449
1g4tFTPThiamine-phosphate synthase/0.449
1uyuCAMCamphor 5-monooxygenase1.14.15.10.449
1x7e244Estrogen receptor/0.449
2cchATPCyclin-dependent kinase 22.7.11.220.449
2wipP49Cyclin-dependent kinase 22.7.11.220.449
3a8wATPProtein kinase C iota type2.7.11.130.449
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.449
3iggEFQCyclin-dependent kinase 22.7.11.220.449
3op5REBSerine/threonine-protein kinase VRK12.7.11.10.449
3pd2A3SThreonine--tRNA ligase6.1.1.30.449
4bfvZVVPantothenate kinase2.7.1.330.449
4bfxZVXPantothenate kinase2.7.1.330.449
4dpuAGSMevalonate diphosphate decarboxylase/0.449
4ejh0QACytochrome P450 2A131.14.14.10.449
4enhFVXCholesterol 24-hydroxylase/0.449
4fk8FADFerredoxin--NADP reductase/0.449
4gk3L87Ephrin type-A receptor 32.7.10.10.449
4jicFMNGTN Reductase/0.449
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.449
4lgaA2OAbscisic acid receptor PYL2/0.449
4lsmNADGlyceraldehyde-3-phosphate dehydrogenase/0.449
4lt63ATPoly(A) polymerase gamma2.7.7.190.449
4oal245Cytokinin dehydrogenase 4/0.449
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.449
4umxNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.449
5fm7ADPRuvB-like helicase/0.449
1udaUFGUDP-glucose 4-epimerase5.1.3.20.448
2bf7HBIPteridine reductase 11.5.1.330.448
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.448
2cig1DGDihydrofolate reductase1.5.1.30.448
2hl1A3SThreonine--tRNA ligase6.1.1.30.448
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.448
2wghDTPRibonucleoside-diphosphate reductase large subunit1.17.4.10.448
2wpa889Cyclin-dependent kinase 22.7.11.220.448
3c1xCKKHepatocyte growth factor receptor2.7.10.10.448
3miaANPCyclin-dependent kinase 92.7.11.220.448
3tnwF18Cyclin-dependent kinase 22.7.11.220.448
3wbbNAPMeso-diaminopimelate D-dehydrogenase/0.448
4bgg844Activin receptor type-12.7.11.300.448
4gu94GUFocal adhesion kinase 12.7.10.20.448
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.448
4l6gCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.448
4lrzADPPEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL2.70.448
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.448
1agwSU2Fibroblast growth factor receptor 1/0.447
1dr3HBIDihydrofolate reductase1.5.1.30.447
1lhwESMSex hormone-binding globulin/0.447
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.447
1oiyN41Cyclin-dependent kinase 22.7.11.220.447
1pdhFASp-hydroxybenzoate hydroxylase/0.447
1rl3PCGcAMP-dependent protein kinase type I-alpha regulatory subunit/0.447
1rm5NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.447
1xzqFONtRNA modification GTPase MnmE3.6.50.447
2c3qGTXGlutathione S-transferase theta-12.5.1.180.447
2iw84SPCyclin-dependent kinase 22.7.11.220.447
2qzsADPGlycogen synthase2.4.1.210.447
2vww7X2Ephrin type-B receptor 42.7.10.10.447
2y5s78HDihydropteroate synthase/0.447
3kb3A8SAbscisic acid receptor PYL2/0.447
4b1rITCTetracycline repressor protein class D/0.447
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.447
4mcc21XtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.447
5bt9NAP3-oxoacyl-(Acyl-carrier-protein) reductase/0.447
5iqiGNPBifunctional AAC/APH2.3.10.447
1e3eNAIAlcohol dehydrogenase 41.1.1.10.446
1ezvUQ6Cytochrome b/0.446
1ja0NAPNADPH--cytochrome P450 reductase/0.446
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.446
1kqoDNDNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.446
1kvkATPMevalonate kinase2.7.1.360.446
1omoNADAlanine dehydrogenase/0.446
1psdNADD-3-phosphoglycerate dehydrogenase1.1.1.950.446
1v7aFRCAdenosine deaminase3.5.4.40.446
2itqITQEpidermal growth factor receptor2.7.10.10.446
2x06NADL-sulfolactate dehydrogenase/0.446
2x7hPFNProstaglandin reductase 310.446
3bhlTHGThymidylate synthase/0.446
3c36KAIGlutamate receptor ionotropic, kainate 1/0.446
3nux3NVCyclin-dependent kinase 62.7.11.220.446
3oom507Activin receptor type-12.7.11.300.446
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4ek1CAMCamphor 5-monooxygenase1.14.15.10.446
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.446
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.446
4qmlANPSerine/threonine-protein kinase 242.7.11.10.446
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.446
1cq7PY5Aspartate aminotransferase2.6.1.10.445
1dz4CAMCamphor 5-monooxygenase1.14.15.10.445
1mewXMPInosine-5'-monophosphate dehydrogenase/0.445
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.445
2b55D31Cyclin-dependent kinase 22.7.11.220.445
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.445
2wxvWXVCyclin-dependent kinase 22.7.11.220.445
2xy93ESAngiotensin-converting enzyme3.2.10.445
3fhxPXLPyridoxal kinase2.7.1.350.445
3fr4F8AFatty acid-binding protein, adipocyte/0.445
3h4vDVPPteridine reductase 11.5.1.330.445
3ha5SFGHydroxymycolate synthase MmaA42.1.10.445
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.445
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.445
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
4pk4ADPUnconventional myosin-VI/0.445
5ej7TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.445
5iu86DZAdenosine receptor A2a/0.445
1j7kATPHolliday junction ATP-dependent DNA helicase RuvB/0.444
1o76CAMCamphor 5-monooxygenase1.14.15.10.444
1xjgDTPVitamin B12-dependent ribonucleotide reductase/0.444
2bfmTOPPteridine reductase 11.5.1.330.444
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.444
2czfXMPOrotidine 5'-phosphate decarboxylase4.1.1.230.444
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.444
2qbmCAMCamphor 5-monooxygenase1.14.15.10.444
2x7jTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.444
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.444
3d8vUD1Bifunctional protein GlmU/0.444
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.444
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.444
3uyt0CKCasein kinase I isoform delta2.7.11.10.444
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.444
3wv7ADPHmd co-occurring protein HcgE/0.444
4hgs15GCasein kinase I isoform gamma-32.7.11.10.444
4uocNCNCinA-like protein/0.444
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.444
1a8rGTPGTP cyclohydrolase 13.5.4.160.443
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.443
1py5PY1TGF-beta receptor type-12.7.11.300.443
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.443
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.443
2a1oCAMCamphor 5-monooxygenase1.14.15.10.443
2abbFMNPentaerythritol tetranitrate reductase/0.443
2bxmIMNSerum albumin/0.443
2oegUPGUDP-glucose pyrophosphorylase/0.443
2p5yNADUDP-glucose 4-epimerase/0.443
2qo9ANPEphrin type-A receptor 32.7.10.10.443
2uzeC95Cyclin-dependent kinase 22.7.11.220.443
2v58LZJBiotin carboxylase6.3.4.140.443
2zvbSAHPrecorrin-3 C17-methyltransferase/0.443
3copADPGlycogen synthase2.4.1.210.443
3f03FMNPentaerythritol tetranitrate reductase/0.443
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
3q1fYPPBeta-lactamase/0.443
3qtqX35Cyclin-dependent kinase 22.7.11.220.443
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.443
4alg1GHBromodomain-containing protein 2/0.443
4dc0NDPPutative ketoacyl reductase1.3.10.443
4g1z0VPVitamin D3 receptor A/0.443
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.443
4h4d10E4-hydroxy-3-methylbut-2-enyl diphosphate reductase/0.443
4ubtCOASteroid 3-ketoacyl-CoA thiolase/0.443
4z17PEPEnolase/0.443
1ep4S11Gag-Pol polyprotein2.7.7.490.442
1f28UMPThymidylate synthase2.1.1.450.442
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.442
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.442
1kl2FONSerine hydroxymethyltransferase/0.442
1lnyIMOAdenylosuccinate synthetase isozyme 1/0.442
1z6tADPApoptotic protease-activating factor 1/0.442
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.442
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.442
2i0ePDSProtein kinase C beta type2.7.11.130.442
2ji9TPWOxalyl-CoA decarboxylase4.1.1.80.442
2qboCAMCamphor 5-monooxygenase1.14.15.10.442
2yboSAHMethyltransferase/0.442
3bgxTMPThymidylate synthase/0.442
3blqATPCyclin-dependent kinase 92.7.11.220.442
3mn6ATPActin-5C/0.442
3p62FMNPentaerythritol tetranitrate reductase/0.442
3p82FMNPentaerythritol tetranitrate reductase/0.442
3r8zZ63Cyclin-dependent kinase 22.7.11.220.442
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.442
4bcoT6QCyclin-dependent kinase 22.7.11.220.442
4dymIYZActivin receptor type-12.7.11.300.442
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.442
4gncASORegucalcin3.1.1.170.442
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.442
4l5aTBNS-methyl-5'-thioadenosine phosphorylase/0.442
5c7oNADGlyceraldehyde-3-phosphate dehydrogenase, testis-specific1.2.1.120.442
5ikqJMSProstaglandin G/H synthase 21.14.99.10.442
1nzdUPGDNA beta-glucosyltransferase/0.441
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.441
1ykr628Cyclin-dependent kinase 22.7.11.220.441
2g0nGDPRas-related C3 botulinum toxin substrate 3/0.441
2npnSAMPutative cobalamin synthesis related protein/0.441
2q46NAPUncharacterized protein At5g02240/0.441
3a62STURibosomal protein S6 kinase beta-12.7.11.10.441
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.441
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.441
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.441
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.441
3zze6XPHepatocyte growth factor receptor2.7.10.10.441
4f650S9Fibroblast growth factor receptor 1/0.441
4fweFADLysine-specific histone demethylase 1B10.441
4hy6FJ1Heat shock protein HSP 90-alpha/0.441
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.441
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.441
4prvADPDNA gyrase subunit B/0.441
4xivACPChemotaxis protein CheA2.7.13.30.441
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.441
5hyrESTEstrogen receptor/0.441
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.440
1c1dNAIPhenylalanine dehydrogenase/0.440
1fxoTMPGlucose-1-phosphate thymidylyltransferase/0.440
1jlrGTPUracil phosphoribosyltransferase/0.440
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.440
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.440
2c6tDT5Cyclin-dependent kinase 22.7.11.220.440
2g9uG27Glycogen phosphorylase, muscle form2.4.1.10.440
2hl0A3SThreonine--tRNA ligase6.1.1.30.440
2puiADPMethylthioribose kinase2.7.1.1000.440
2vw5BC6ATP-dependent molecular chaperone HSP82/0.440
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.440
3bhtMFRCyclin-dependent kinase 22.7.11.220.440
3cquCQURAC-alpha serine/threonine-protein kinase2.7.11.10.440
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3flwFLWMitogen-activated protein kinase 14/0.440
3h3qH13Collagen type IV alpha-3-binding protein/0.440
3rkb12ZCyclin-dependent kinase 22.7.11.220.440
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.440
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.440
4ccbOFGALK tyrosine kinase receptor2.7.10.10.440
4erkOLOMitogen-activated protein kinase 12.7.11.240.440
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.440
4k39SAMAnaerobic sulfatase-maturating enzyme1.8.980.440
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.440
4or0NPSSerum albumin/0.440
4prxADPDNA gyrase subunit B/0.440
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440