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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.58

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.581.000
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.606
1s63778Protein farnesyltransferase subunit beta2.5.1.580.605
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.591
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.590
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.588
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.582
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.572
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.567
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.567
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.562
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.556
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.546
3pz43PZProtein farnesyltransferase subunit beta2.5.1.580.546
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.545
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.545
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.532
4gtp7TPProtein farnesyltransferase subunit beta2.5.1.580.531
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.500
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.494
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.492
4gtr7TRProtein farnesyltransferase subunit beta2.5.1.580.492
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.489
4lnbED5CaaX farnesyltransferase beta subunit Ram1/0.484
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.477
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.477
4gtm7TMProtein farnesyltransferase subunit beta2.5.1.580.476
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.466
4gto7TOProtein farnesyltransferase subunit beta2.5.1.580.463
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.449
1n4qLYS_CYS_VAL_ILE_LEUGeranylgeranyl transferase type-1 subunit beta2.5.1.590.448