sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3eg5 | GNP | Cell division control protein 42 homolog |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 1.000 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.599 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.567 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.548 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.547 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.544 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.537 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.534 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.532 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.529 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.525 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.525 | |
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.525 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.523 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.523 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.520 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.520 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.517 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.516 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.515 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.512 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.510 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.508 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.507 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.505 | |
| 4nyi | GNP | GTPase HRas | / | 0.502 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.500 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.500 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.499 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.497 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.494 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.493 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.493 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.492 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.491 | |
| 4nyj | GNP | GTPase HRas | / | 0.491 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.489 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.488 | |
| 3lbn | GNP | GTPase HRas | / | 0.487 | |
| 2c5l | GTP | GTPase HRas | / | 0.485 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.485 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.484 | |
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.484 | |
| 4mit | GTP | Rho-related protein racC | / | 0.483 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.482 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.481 | |
| 3oiv | GNP | GTPase HRas | / | 0.480 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.479 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.478 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.477 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.477 | |
| 4gzl | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.477 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.477 | |
| 1z2c | GNP | Rho-related GTP-binding protein RhoC | / | 0.476 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.476 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.475 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.473 | |
| 3sbe | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.473 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.472 | |
| 3oiu | GNP | GTPase HRas | / | 0.472 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.471 | |
| 3v4f | GNP | GTPase HRas | / | 0.470 | |
| 4dlt | GNP | GTPase HRas | / | 0.469 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.469 | |
| 3i3s | GNP | GTPase HRas | / | 0.468 | |
| 3ddc | GNP | GTPase HRas | / | 0.465 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.465 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.463 | |
| 4k81 | GTP | GTPase HRas | / | 0.461 | |
| 3tgp | GNP | GTPase HRas | / | 0.458 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.457 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.452 | |
| 2rgb | GNP | GTPase HRas | / | 0.452 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.450 | |
| 3qbt | GNP | Ras-related protein Rab-8A | / | 0.450 | |
| 2p20 | PRX | Acetyl-coenzyme A synthetase | / | 0.448 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.448 | |
| 3rs5 | GNP | GTPase HRas | / | 0.447 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.446 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.446 | |
| 1z0a | GDP | Ras-related protein Rab-2A | / | 0.445 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.445 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.444 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2rgc | GNP | GTPase HRas | / | 0.444 | |
| 3kud | GDP | GTPase HRas | / | 0.444 | |
| 2rge | GNP | GTPase HRas | / | 0.443 |