sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3efv | NAD | Putative succinate-semialdehyde dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3efv | NAD | Putative succinate-semialdehyde dehydrogenase | / | 1.000 | |
| 4itb | NDP | Succinate-semialdehyde dehydrogenase | / | 0.506 | |
| 2jg7 | NAD | Antiquitin | / | 0.478 | |
| 2j6l | NAI | Alpha-aminoadipic semialdehyde dehydrogenase | 1.2.1.31 | 0.470 | |
| 2bhp | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.465 | |
| 2ehu | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.456 | |
| 2o2q | NAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.456 | |
| 4ihi | NAD | Probable pyrroline-5-carboxylate dehydrogenase RocA | / | 0.455 | |
| 4pz2 | NAD | Aldehyde dehydrogenase 2-6 | / | 0.454 | |
| 1o04 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.450 | |
| 1o01 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.448 | |
| 2ehq | NAP | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.448 | |
| 2onp | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.444 | |
| 3haz | NAD | Bifunctional protein PutA | / | 0.444 | |
| 2eii | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.442 | |
| 4fqf | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.442 | |
| 4v37 | NAD | Betaine aldehyde dehydrogenase, chloroplastic | 1.2.1.8 | 0.441 |