scPDB - Distribution of Binding site Similarity values of 3e8n entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3e8n	VRA	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3e8n	VRA	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	1.000
1s9j	BBM	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.539
3dv3	MEK	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.533
3os3	3OS	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.476
4lmn	EUI	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.472
1fm4	DXC	Major pollen allergen Bet v 1-L	/	0.457
3pp1	IZG	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.454
4an2	EUI	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.443
4an9	2P7	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.443
3orn	3OR	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.442