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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.585
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.571
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.546
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.533
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.518
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.518
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.497
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.491
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.484
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442