scPDB - Distribution of Binding site Similarity values of 3dv0 entry / Site 4

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3dv0	TPW	Pyruvate dehydrogenase E1 component subunit alpha	1.2.4.1

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3dv0	TPW	Pyruvate dehydrogenase E1 component subunit alpha	1.2.4.1	1.000
3dv0	TPW	Pyruvate dehydrogenase E1 component subunit beta	1.2.4.1	1.000
3zhs	TD6	Multifunctional 2-oxoglutarate metabolism enzyme	1.2.4.2	0.483
2j9f	THV	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial	1.2.4.4	0.481
2j9f	THV	2-oxoisovalerate dehydrogenase subunit beta, mitochondrial	1.2.4.4	0.481
3zht	TD9	Multifunctional 2-oxoglutarate metabolism enzyme	1.2.4.2	0.470
2o1x	TDP	1-deoxy-D-xylulose-5-phosphate synthase	2.2.1.7	0.462
1umc	TDP	2-oxoisovalerate dehydrogenase subunit alpha	1.2.4.4	0.454
1umc	TDP	2-oxoisovalerate dehydrogenase subunit beta	1.2.4.4	0.454
3zhq	TPP	Multifunctional 2-oxoglutarate metabolism enzyme	1.2.4.2	0.445
3zhu	TD8	Multifunctional 2-oxoglutarate metabolism enzyme	1.2.4.2	0.444
2g25	TDK	Pyruvate dehydrogenase E1 component	1.2.4.1	0.442
3zhv	TDW	Multifunctional 2-oxoglutarate metabolism enzyme	1.2.4.2	0.440