scPDB - Distribution of Binding site Similarity values of 3drc entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3drc	MTX	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3drc	MTX	Dihydrofolate reductase	1.5.1.3	1.000
1drb	MTX	Dihydrofolate reductase	1.5.1.3	0.691
1dhi	MTX	Dihydrofolate reductase	1.5.1.3	0.633
4dfr	MTX	Dihydrofolate reductase	1.5.1.3	0.613
1dra	MTX	Dihydrofolate reductase	1.5.1.3	0.605
3och	2MX	Dihydrofolate reductase	1.5.1.3	0.602
1tdr	MTX	Dihydrofolate reductase	1.5.1.3	0.601
1dhj	MTX	Dihydrofolate reductase	1.5.1.3	0.595
1rb3	MTX	Dihydrofolate reductase	1.5.1.3	0.579
1dds	MTX	Dihydrofolate reductase	1.5.1.3	0.565
1ddr	MTX	Dihydrofolate reductase	1.5.1.3	0.559
2drc	MTX	Dihydrofolate reductase	1.5.1.3	0.556
1jol	FFO	Dihydrofolate reductase	1.5.1.3	0.554
1dyj	DDF	Dihydrofolate reductase	1.5.1.3	0.537
1rb2	FOL	Dihydrofolate reductase	1.5.1.3	0.504
5hi6	MTX	Dihydrofolate reductase	/	0.504
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.491
1re7	FOL	Dihydrofolate reductase	1.5.1.3	0.489
1rf7	DHF	Dihydrofolate reductase	1.5.1.3	0.480
1dyh	DZF	Dihydrofolate reductase	1.5.1.3	0.475
2w9s	TOP	Dihydrofolate reductase type 1 from Tn4003	1.5.1.3	0.451
1dyi	FOL	Dihydrofolate reductase	1.5.1.3	0.446