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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3cv7C2UAlcohol dehydrogenase [NADP(+)]1.1.1.2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3cv7C2UAlcohol dehydrogenase [NADP(+)]1.1.1.21.000
3fx4FX4Alcohol dehydrogenase [NADP(+)]1.1.1.20.626
3h4gFIDAlcohol dehydrogenase [NADP(+)]1.1.1.20.574
5liu388Aldo-keto reductase family 1 member B101.1.10.548
2ikj393Aldose reductase1.1.1.210.545
2pd9FIDAldose reductase1.1.1.210.543
2f2kTGGAldose reductase1.1.1.210.533
2pdmZSTAldose reductase1.1.1.210.528
4ga8SBIAldo-keto reductase family 1 member B101.1.10.524
2pzn393Aldose reductase1.1.1.210.523
2inzOHPAldose reductase1.1.1.210.522
1z8962PAldose reductase1.1.1.210.519
2agtFIDAldose reductase1.1.1.210.519
2pdwFIDAldose reductase1.1.1.210.519
2fz8ZSTAldose reductase1.1.1.210.517
2is72CLAldose reductase1.1.1.210.515
3g5eQ74Aldose reductase1.1.1.210.513
3ghuLDTAldose reductase1.1.1.210.513
1us0LDTAldose reductase1.1.1.210.512
2pdyFIDAldose reductase1.1.1.210.512
3lz5LDTAldose reductase1.1.1.210.512
3af3GCPPantothenate kinase2.7.1.330.510
1ekoI84Aldose reductase1.1.1.210.509
2i16LDTAldose reductase1.1.1.210.509
3m64393Aldose reductase1.1.1.210.508
2pdg47DAldose reductase1.1.1.210.507
3mc5393Aldose reductase1.1.1.210.505
3s3gTLTAldose reductase1.1.1.210.505
1t40ID5Aldose reductase1.1.1.210.504
3v35NTIAldose reductase1.1.1.210.504
4wevSUZAldo-keto reductase family 1 member B101.1.10.503
1pwmFIDAldose reductase1.1.1.210.501
1ah0SBIAldose reductase1.1.1.210.500
1ef3FIDAldose reductase1.1.1.210.500
1el3I84Aldose reductase1.1.1.210.500
2iki388Aldose reductase1.1.1.210.500
2qxwLDTAldose reductase1.1.1.210.499
3ghrLDTAldose reductase1.1.1.210.499
4gca2X9Aldose reductase1.1.1.210.499
2pdp393Aldose reductase1.1.1.210.498
3af2ACPPantothenate kinase2.7.1.330.497
3m0iZSTAldose reductase1.1.1.210.497
2duxZSTAldose reductase1.1.1.210.496
2i17LDTAldose reductase1.1.1.210.496
2pdiZSTAldose reductase1.1.1.210.496
1pwlBFIAldose reductase1.1.1.210.494
2pdn47DAldose reductase1.1.1.210.494
2pdu393Aldose reductase1.1.1.210.494
2ikhLITAldose reductase1.1.1.210.492
2pdc393Aldose reductase1.1.1.210.492
3apwDP0Alpha-1-acid glycoprotein 2/0.492
2ipw2CLAldose reductase1.1.1.210.491
2pdh47DAldose reductase1.1.1.210.491
2hvoZSTAldose reductase1.1.1.210.490
2pdfZSTAldose reductase1.1.1.210.490
2qx7NAPEugenol synthase 11.1.1.3180.490
2zsdCOAPantothenate kinase2.7.1.330.490
3ghsLDTAldose reductase1.1.1.210.490
2hvnZSTAldose reductase1.1.1.210.489
2ea4F79Methionine aminopeptidase 2/0.488
3lqlLDTAldose reductase1.1.1.210.488
3p2vDOYAldose reductase1.1.1.210.488
1yw8A75Methionine aminopeptidase 2/0.487
2iqdLPAAldose reductase1.1.1.210.487
3mb9ZSTAldose reductase1.1.1.210.487
2tplHPPTyrosine phenol-lyase4.1.99.20.486
3c1oNAPEugenol synthase/0.486
4mv1ADPBiotin carboxylase6.3.4.140.486
1t41ID5Aldose reductase1.1.1.210.485
1z3n3NAAldose reductase1.1.1.210.485
2pdkSBIAldose reductase1.1.1.210.485
2r6kGTXGlutathione S-transferase A12.5.1.180.484
3lenZSTAldose reductase1.1.1.210.484
4ba5PXGProbable aminotransferase/0.483
3m4h388Aldose reductase1.1.1.210.482
1ah3TOLAldose reductase1.1.1.210.481
2zs8ADPPantothenate kinase2.7.1.330.481
3u2cSUZAldose reductase1.1.1.210.481
4dyp0MSNucleoprotein/0.481
1lkeDOGBilin-binding protein/0.479
3af4GCPPantothenate kinase2.7.1.330.479
4a4xJUPSerine/threonine-protein kinase Nek22.7.11.10.479
4ckcSAHmRNA-capping enzyme catalytic subunit2.1.1.560.479
1toiHCIAspartate aminotransferase2.6.1.10.478
1zuaTOLAldo-keto reductase family 1 member B101.1.10.478
2pd5ZSTAldose reductase1.1.1.210.477
1p8dCO1Oxysterols receptor LXR-beta/0.476
1xidASCXylose isomerase5.3.1.50.476
2fz9ZSTAldose reductase1.1.1.210.476
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.476
2zs9ADPPantothenate kinase2.7.1.330.476
3t423T4Aldose reductase1.1.1.210.476
4yu153NAldose reductase1.1.1.210.476
3sfxJANUncharacterized protein/0.475
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.475
4xo7ASDAldo-keto reductase family 1 member C2/0.475
1gsfEAAGlutathione S-transferase A12.5.1.180.474
1ivrCBAAspartate aminotransferase, mitochondrial2.6.1.10.474
2fzdTOLAldose reductase1.1.1.210.474
2getCOKPantothenate kinase2.7.1.330.474
3n0yAPCAdenylate cyclase 2/0.474
4aoaIK2Beta-phenylalanine transaminase2.6.10.474
4gabFIDAldo-keto reductase family 1 member B101.1.10.474
2haiPFIPolyprotein/0.473
1az1ALRAldose reductase1.1.1.210.472
1yunATPProbable nicotinate-nucleotide adenylyltransferase2.7.7.180.472
2zsaADPPantothenate kinase2.7.1.330.472
4pnmNU1Tankyrase-22.4.2.300.472
5c1gGDUHisto-blood group ABO system transferase/0.472
5dsg0HKMuscarinic acetylcholine receptor M4/0.472
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.471
2zseACPPantothenate kinase2.7.1.330.471
4bfyZVYPantothenate kinase2.7.1.330.471
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.471
4qfzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.471
1gpeFADGlucose oxidase1.1.3.40.470
1r58AO5Methionine aminopeptidase 2/0.470
2dv0ZSTAldose reductase1.1.1.210.470
4bzbDGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.470
4dbs0HVAldo-keto reductase family 1 member C3/0.470
4qfxDGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.470
2duzZSTAldose reductase1.1.1.210.469
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.469
1dp2LPBThiosulfate sulfurtransferase/0.468
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.468
1mapKETAspartate aminotransferase, mitochondrial2.6.1.10.468
2qw8NAPEugenol synthase 11.1.1.3180.468
3af0GDPPantothenate kinase2.7.1.330.468
3mz9BHNNickel-binding periplasmic protein/0.468
4gaaBESLeukotriene A(4) hydrolase/0.468
2fzbTOLAldose reductase1.1.1.210.467
2pdbZSTAldose reductase1.1.1.210.467
2qmeGCPRas-related C3 botulinum toxin substrate 3/0.467
2zsbADPPantothenate kinase2.7.1.330.467
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.467
4uy6SAHHistidine N-alpha-methyltransferase/0.467
1eyyNAPNADP-dependent fatty aldehyde dehydrogenase1.2.1.40.466
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.466
1qv0CZHObelin/0.466
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.466
2vd0D27Hematopoietic prostaglandin D synthase/0.466
3ld5LDTAldose reductase1.1.1.210.466
4imuH4BNitric oxide synthase, brain1.14.13.390.466
1a8t061Metallo-beta-lactamase type 2/0.465
1maqPGUAspartate aminotransferase, mitochondrial2.6.1.10.465
2xejOKDGlutamate carboxypeptidase 23.4.17.210.465
3d2dRENReticuline oxidase1.21.3.30.465
3lboLDTAldose reductase1.1.1.210.465
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.465
1qiqACCIsopenicillin N synthase1.21.3.10.464
1yw7A41Methionine aminopeptidase 2/0.464
3zo7K6HMuconolactone Delta-isomerase/0.464
3zoiM2WIsopenicillin N synthase1.21.3.10.464
4bfuZVUPantothenate kinase2.7.1.330.464
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.464
1qv1CZHObelin/0.463
1x2bSTXProline iminopeptidase3.4.11.50.463
1yw9A84Methionine aminopeptidase 2/0.463
2hv5ZSTAldose reductase1.1.1.210.463
2pdlTOLAldose reductase1.1.1.210.463
4itxIN5Cystathionine beta-lyase MetC4.4.1.80.463
4qa0SHHHistone deacetylase 83.5.1.980.463
1dgbNDPCatalase1.11.1.60.462
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.462
1ieiZESAldose reductase1.1.1.210.462
1n0sFLUBilin-binding protein/0.462
1v93FADMethylenetetrahydrofolate reductase/0.462
2bd0BIOSepiapterin reductase/0.462
2gevCOKPantothenate kinase2.7.1.330.462
2pdxZSTAldose reductase1.1.1.210.462
2r6jNDPEugenol synthase 11.1.1.3180.462
3af1GDPPantothenate kinase2.7.1.330.462
3c10TSNHistone deacetylase 73.5.1.980.462
4dbw511Aldo-keto reductase family 1 member C3/0.462
4xczT3QQdtf/0.462
1rxjBNIStreptavidin/0.461
1tojHCIAspartate aminotransferase2.6.1.10.461
2geuCOKPantothenate kinase2.7.1.330.461
2h63NAPBiliverdin reductase A1.3.1.240.461
2ipjFFAAldo-keto reductase family 1 member C2/0.461
2xuoTZ4Acetylcholinesterase3.1.1.70.461
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.461
3n61H4BNitric oxide synthase, brain1.14.13.390.461
3zrrPXGSerine-pyruvate aminotransferase (AgxT)/0.461
4b64NAPL-ornithine N(5)-monooxygenase/0.461
4kfjFOLDihydrofolate reductase1.5.1.30.461
1akbPPDAspartate aminotransferase, mitochondrial2.6.1.10.460
2qg4UGAUDP-glucose 6-dehydrogenase1.1.1.220.460
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.460
4jq4IMNAldo-keto reductase family 1 member C2/0.460
1k3yGTXGlutathione S-transferase A12.5.1.180.459
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.459
2bn4FADNADPH--cytochrome P450 reductase/0.459
2poqISDTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase1.3.1.200.459
2xegCI9Glutamate carboxypeptidase 23.4.17.210.459
3pahXDEPhenylalanine-4-hydroxylase1.14.16.10.459
4dya0MFNucleoprotein/0.459
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.458
2f0y3MNProtein farnesyltransferase subunit beta2.5.1.580.458
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.458
3l0hGTXGlutathione S-transferase A12.5.1.180.458
3nn6HNK6-hydroxy-L-nicotine oxidase/0.458
3stdMQ0Scytalone dehydratase4.2.1.940.458
3tydXHPDihydropteroate synthase/0.458
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.458
4rkdKETAminotransferase/0.458
4u163C0Muscarinic acetylcholine receptor M3/0.458
1m2xMCOMetallo-beta-lactamase type 2/0.457
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.457
2ea2F77Methionine aminopeptidase 2/0.457
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
2vkuDBELanosterol 14-alpha demethylase1.14.13.700.457
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.457
3mjrAC2Deoxycytidine kinase2.7.1.740.457
3pz43PZProtein farnesyltransferase subunit beta2.5.1.580.457
4j7gTRHPCZA361.3/0.457
4l1xSTRAldo-keto reductase family 1 member C2/0.457
5arkUMPRibonuclease 43.1.270.457
4u140HKMuscarinic acetylcholine receptor M3/0.457
1cq7PY5Aspartate aminotransferase2.6.1.10.456
1mrqSTRAldo-keto reductase family 1 member C1/0.456
1pl2ABYGlutathione S-transferase A12.5.1.180.456
3aezGDPPantothenate kinase2.7.1.330.456
3fufBESLeukotriene A-4 hydrolase3.3.2.60.456
3rc7TLOSugar 3-ketoreductase/0.456
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
4stdBFSScytalone dehydratase4.2.1.940.456
5kf2ACOPredicted acetyltransferase/0.456
1ihiIU5Aldo-keto reductase family 1 member C2/0.455
3lbnGNPGTPase HRas/0.455
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.455
4chzH75Integrase/0.455
4ivrN50Thymidine kinase/0.455
4wctFADFructosyl amine:oxygen oxidoreductase/0.455
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.455
1qjfACSIsopenicillin N synthase1.21.3.10.454
3c0zSHHHistone deacetylase 73.5.1.980.454
3eblGA4Gibberellin receptor GID1/0.454
3elePLPAminotransferase/0.454
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.454
5kf9ACOPredicted acetyltransferase/0.454
1ascNPLAspartate aminotransferase2.6.1.10.453
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
1s36CEIObelin/0.453
1x28PGUAspartate aminotransferase2.6.1.10.453
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.453
2w6cBM4Acetylcholinesterase3.1.1.70.453
2xnmWGZSerine/threonine-protein kinase Nek22.7.11.10.453
3c74ANUUridine phosphorylase2.4.2.30.453
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.453
3ftxBESLeukotriene A-4 hydrolase3.3.2.60.453
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
3pcg4HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.453
3pcg4HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.453
3uyk0CXProbable NDP-rhamnosyltransferase/0.453
1ahgTYR_PLPAspartate aminotransferase2.6.1.10.452
1cozCTPGlycerol-3-phosphate cytidylyltransferase2.7.7.390.452
1eouSMSCarbonic anhydrase 24.2.1.10.452
1nmkSFMPeptidyl-prolyl cis-trans isomerase A5.2.1.80.452
2c6c24IGlutamate carboxypeptidase 23.4.17.210.452
3ed1GA3Gibberellin receptor GID1/0.452
3nh8DC2N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)3.5.1.1140.452
4afeGGYSerine/threonine-protein kinase Nek22.7.11.10.452
4qak2AMRNA 2',3'-cyclic phosphodiesterase/0.452
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
2nvcITAAldose reductase1.1.1.210.451
2xkeWI2Serine/threonine-protein kinase Nek22.7.11.10.451
3ddcGNPGTPase HRas/0.451
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3khuUPGUDP-glucose 6-dehydrogenase1.1.1.220.451
3kslSZHProtein farnesyltransferase subunit beta2.5.1.580.451
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.451
4oex5EOcGMP-specific 3',5'-cyclic phosphodiesterase/0.451
4pabTHGDimethylglycine dehydrogenase, mitochondrial1.5.8.40.451
5stdUNNScytalone dehydratase4.2.1.940.451
1b2rFADFerredoxin--NADP reductase1.18.1.20.450
1bk0ACVIsopenicillin N synthase1.21.3.10.450
1dgfNDPCatalase1.11.1.60.450
1froGSBLactoylglutathione lyase4.4.1.50.450
1gt5BZQOdorant-binding protein/0.450
1isgAGSADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 23.2.2.60.450
1ogxEQUSteroid Delta-isomerase5.3.3.10.450
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
2d2gDZZPhosphotriesterase/0.450
2wgs1AZGlutamine synthetase6.3.1.20.450
2xkdT3MSerine/threonine-protein kinase Nek22.7.11.10.450
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.450
3d73NBBPheromone-binding protein ASP1/0.450
3gf4UPGUDP-galactopyranose mutase5.4.99.90.450
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.450
3h3r14HCollagen type IV alpha-3-binding protein/0.450
3jt4H4BNitric oxide synthase, brain1.14.13.390.450
3qh23NMThiazole tautomerase/0.450
3wtiCT4Acetylcholine-binding protein/0.450
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.450
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.450
4bfwZVWPantothenate kinase2.7.1.330.450
1bh5GTXLactoylglutathione lyase4.4.1.50.449
1crbRTLRetinol-binding protein 1/0.449
1lelBH7Avidin/0.449
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.449
2ct8MSPMethionine--tRNA ligase6.1.1.100.449
2gesCOKPantothenate kinase2.7.1.330.449
2mjpANPdITP/XTP pyrophosphatase3.6.1.190.449
2vbpVB1Isopenicillin N synthase1.21.3.10.449
3h3t16HCollagen type IV alpha-3-binding protein/0.449
3ho2N323-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.449
3v1s0LHStrictosidine synthase4.3.3.20.449
4k88HFGBifunctional glutamate/proline--tRNA ligase6.1.1.150.449
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.449
5c80URIUridine phosphorylase/0.449
1phqFPE2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.448
1qinGIPLactoylglutathione lyase4.4.1.50.448
1t3zCAOFormyl-CoA:oxalate CoA-transferase/0.448
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
2ga2A19Methionine aminopeptidase 2/0.448
2jb4A14Isopenicillin N synthase1.21.3.10.448
2rds1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.448
2ykvIK2Beta-transaminase/0.448
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.448
3aklADPSerine/threonine-protein kinase CtkA2.7.11.10.448
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.448
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.448
3hv3R49Mitogen-activated protein kinase 14/0.448
4uz6SCRPalmitoleoyl-protein carboxylesterase NOTUM/0.448
4xwtU5PRibonuclease J/0.448
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.447
1rvvINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.447
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.447
2zshGA3Gibberellin receptor GID1A30.447
3ba6AN2Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.447
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
3mzbBHRNickel-binding periplasmic protein/0.447
3nxrD2DDihydrofolate reductase1.5.1.30.447
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.447
4c3yANB3-ketosteroid dehydrogenase/0.447
4gtv7TRGeranylgeranyl transferase type-2 subunit beta2.5.1.600.447
4tjy3GNTankyrase-22.4.2.300.447
1afsTES3-alpha-hydroxysteroid dehydrogenase1.1.1.500.446
1touB1VFatty acid-binding protein, adipocyte/0.446
1uogP1CDeacetoxycephalosporin C synthase1.14.20.10.446
1upw444Oxysterols receptor LXR-beta/0.446
2f3815MAldo-keto reductase family 1 member C3/0.446
2gqnBLPCystathionine beta-lyase MetC4.4.1.80.446
2pdj393Aldose reductase1.1.1.210.446
2xujTZ5Acetylcholinesterase3.1.1.70.446
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.446
3l3lL3LPoly [ADP-ribose] polymerase 12.4.2.300.446
3oiwGNPGTPase HRas/0.446
3tfjTHGDimethylsulfonioproprionate demethylase DmdA2.1.1.2690.446
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
4g0k0VSGlutathionyl-hydroquinone reductase YqjG1.80.446
5cc9DDFDihydrofolate reductase1.5.1.30.446
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.445
1dggNDPCatalase1.11.1.60.445
1ohjCOPDihydrofolate reductase1.5.1.30.445
1u70MTXDihydrofolate reductase1.5.1.30.445
1v08NTZ4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.445
1vhnFMNtRNA-dihydrouridine synthase/0.445
1w2cANPInositol-trisphosphate 3-kinase A2.7.1.1270.445
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.445
2gvvDI9Diisopropyl-fluorophosphatase3.1.8.20.445
2jl1NAPTriphenylmethane reductase/0.445
2vrjNCWBeta-glucosidase A3.2.1.210.445
2xnoED8Serine/threonine-protein kinase Nek22.7.11.10.445
3bmqAX5Pteridine reductase/0.445
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.445
4iah1DXAlr2278 protein/0.445
4mv3ACPBiotin carboxylase6.3.4.140.445
5kgpACOPredicted acetyltransferase/0.445
4daj0HKMuscarinic acetylcholine receptor M3/0.445
1e2lTMCThymidine kinase/0.444
1h69ARHNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.444
2bjsACVIsopenicillin N synthase1.21.3.10.444
2d06ESTSulfotransferase 1A12.8.2.10.444
2qcxPF1Aminopyrimidine aminohydrolase/0.444
2r86ATP5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase/0.444
2w6oOA3Biotin carboxylase6.3.4.140.444
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.444
3htjETEbrA repressor/0.444
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.444
3pitGNPRas-related protein M-Ras/0.444
3s3vTOPDihydrofolate reductase1.5.1.30.444
4dk70KSOxysterols receptor LXR-beta/0.444
4iix1EGMicrocin C7 self-immunity protein MccF/0.444
4jq2SUZAldo-keto reductase family 1 member C2/0.444
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.444
4lngJANCaaX farnesyltransferase beta subunit Ram1/0.444
4zmeADNMyosin heavy chain kinase A2.7.11.70.444
1cq6PY4Aspartate aminotransferase2.6.1.10.443
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1o1t2NHProtein farnesyltransferase subunit beta2.5.1.580.443
1qw514WNitric oxide synthase, inducible1.14.13.390.443
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.443
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.443
3o9pMHIPeriplasmic murein peptide-binding protein/0.443
4b66NAPL-ornithine N(5)-monooxygenase/0.443
4bfsZVSPantothenate kinase2.7.1.330.443
4mz7DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.443
4nhyPD2Prolyl 3-hydroxylase OGFOD11.14.110.443
5k8bPDG8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase/0.443
5jtbZMAAdenosine receptor A2a/0.443
1dr4HBIDihydrofolate reductase1.5.1.30.442
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1hb3SCVIsopenicillin N synthase1.21.3.10.442
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.442
1xq04TRCarbonic anhydrase 24.2.1.10.442
2b8jADNClass B acid phosphatase3.1.3.20.442
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.442
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.442
2iejS48Protein farnesyltransferase subunit beta2.5.1.580.442
2vcmM11Isopenicillin N synthase1.21.3.10.442
2vcwZZAHematopoietic prostaglandin D synthase/0.442
2w6pOA4Biotin carboxylase6.3.4.140.442
2x9vTMQPteridine reductase/0.442
2zhw12UProthrombin3.4.21.50.442
3eon341Glutaryl-CoA dehydrogenase/0.442
3vf60H6Glucokinase2.7.1.20.442
3x065GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.442
3zkuHCVIsopenicillin N synthase1.21.3.10.442
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.442
4xoiGTPTransforming protein RhoA/0.442
4zo3C6LAcylhomoserine lactonase/0.442
5d1bTSNHistone deacetylase 83.5.1.980.442
1argPPDAspartate aminotransferase2.6.1.10.441
1cq8PY6Aspartate aminotransferase2.6.1.10.441
1mlzPLPAdenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.441
2r1nEPLPhosphotriesterase/0.441
2vrbNAPTriphenylmethane reductase/0.441
3gn73GNPoly [ADP-ribose] polymerase 12.4.2.300.441
3hkuTORCarbonic anhydrase 24.2.1.10.441
3nxtD2EDihydrofolate reductase1.5.1.30.441
3vgnFNNSteroid Delta-isomerase5.3.3.10.441
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.441
4bfxZVXPantothenate kinase2.7.1.330.441
4jseH4BNitric oxide synthase, brain1.14.13.390.441
4khnXG4DNA-directed DNA polymerase/0.441
4kykIMNLactoylglutathione lyase4.4.1.50.441
5dsyUHBPoly [ADP-ribose] polymerase 22.4.2.300.441
5kf8ACOPredicted acetyltransferase/0.441
1hb1OCVIsopenicillin N synthase1.21.3.10.440
1i59ADPChemotaxis protein CheA2.7.13.30.440
1l8qADPChromosomal replication initiator protein DnaA/0.440
1qipGNBLactoylglutathione lyase4.4.1.50.440
1tg2H2BPhenylalanine-4-hydroxylase1.14.16.10.440
1towCRZFatty acid-binding protein, adipocyte/0.440
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
2ix5CAAAcyl-coenzyme A oxidase 4, peroxisomal1.3.3.60.440
3gyaCOAGCN5-related N-acetyltransferase/0.440
3h3qH13Collagen type IV alpha-3-binding protein/0.440
3hu3AGSTransitional endoplasmic reticulum ATPase3.6.4.60.440
3s8xE59Carbonic anhydrase 24.2.1.10.440
3wi2P98cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
3znrNU9Histone deacetylase 73.5.1.980.440
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.440
4cbyKEEHistone deacetylase 43.5.1.980.440
4fal0T0Aldo-keto reductase family 1 member C3/0.440
4jq3ZOMAldo-keto reductase family 1 member C2/0.440
4jtrIZPAldo-keto reductase family 1 member C2/0.440
4xt8TMQPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.440
5cxv0HKMuscarinic acetylcholine receptor M1/0.440