Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3ctj320Hepatocyte growth factor receptor2.7.10.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3ctj320Hepatocyte growth factor receptor2.7.10.11.000
4eevL1XHepatocyte growth factor receptor2.7.10.10.584
3ce31FNHepatocyte growth factor receptor2.7.10.10.556
3eta351Insulin receptor2.7.10.10.501
4eyjN61Mitogen-activated protein kinase 132.7.11.240.496
4agwNG7Proto-oncogene tyrosine-protein kinase Src2.7.10.20.494
3b8q900Vascular endothelial growth factor receptor 22.7.10.10.493
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.492
4kaoKAOFocal adhesion kinase 12.7.10.20.477
2og81N8Tyrosine-protein kinase Lck2.7.10.20.476
2p4iMR9Angiopoietin-1 receptor2.7.10.10.470
3tubFPUTyrosine-protein kinase SYK2.7.10.20.464
3iw8HIZMitogen-activated protein kinase 14/0.459
4aseAV9Vascular endothelial growth factor receptor 22.7.10.10.458
4o2z046Mitogen-activated protein kinase/0.456
4c8b0LIReceptor-interacting serine/threonine-protein kinase 22.7.11.10.450
3vnt0JAVascular endothelial growth factor receptor 22.7.10.10.443
3fzt4JZProtein-tyrosine kinase 2-beta2.7.10.20.441