sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 1.000 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.618 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.527 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.515 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.510 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.508 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.505 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.505 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.505 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.503 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.503 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.502 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.500 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.499 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.498 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.497 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.497 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.496 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.495 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.495 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.495 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.495 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.493 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.492 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.492 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.491 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.491 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.490 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.490 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.490 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.490 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.490 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.490 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.490 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.489 | |
| 3zuy | TCH | Transporter | / | 0.489 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.489 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.488 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.487 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.487 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.487 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.487 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.487 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.487 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.486 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.485 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.485 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.485 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.484 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.484 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.484 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.484 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.483 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.483 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.483 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.482 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.482 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.482 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.482 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.482 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.482 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.482 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.482 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.481 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.481 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.481 | |
| 2y3r | TRK | TamL | / | 0.481 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.481 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.481 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.481 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.480 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.480 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.479 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.479 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.479 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.479 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.478 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.478 | |
| 3qly | 55V | Uncharacterized protein | / | 0.478 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.478 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.477 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.477 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.477 | |
| 2y3s | TIR | TamL | / | 0.477 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.477 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.477 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.477 | |
| 4l8u | 9AZ | Serum albumin | / | 0.477 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.476 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.476 | |
| 2jfg | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.476 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.476 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.476 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.476 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.476 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.476 | |
| 4gah | 0ET | Acyl-coenzyme A thioesterase THEM4 | 3.1.2.2 | 0.476 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.476 | |
| 1eio | GCH | Gastrotropin | / | 0.475 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.475 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.475 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.475 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.475 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.474 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.474 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.474 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.474 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.473 | |
| 1fml | RTL | Retinol dehydratase | / | 0.473 | |
| 1r2j | FAD | FkbI | / | 0.473 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.473 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.473 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.473 | |
| 4l9q | 9TP | Serum albumin | / | 0.473 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.473 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.472 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.472 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.471 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.471 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.471 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.471 | |
| 2r3y | VAL_TYR_TRP_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.471 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.471 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.470 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.470 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.469 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
| 2f1k | NAP | Prephenate dehydrogenase | / | 0.469 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.469 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.469 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.469 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.469 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.469 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.469 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.469 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.468 | |
| 1enp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.468 | |
| 1tv8 | SAM | GTP 3',8-cyclase | 4.1.99.18 | 0.468 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.468 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.468 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.468 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.468 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.468 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.468 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.468 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1llq | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.467 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.467 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.467 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.466 | |
| 1rv1 | IMZ | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.466 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.466 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.466 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.466 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.466 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 2ves | GVR | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.466 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.466 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.466 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.465 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.465 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.465 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.465 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.465 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.465 | |
| 3lu8 | IQX | Serum albumin | / | 0.465 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.465 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.464 | |
| 1hdg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.464 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.464 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.464 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.464 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.464 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.464 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.464 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.464 | |
| 4b10 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.464 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.464 | |
| 4lvb | 20N | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.464 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.463 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.463 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.463 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.463 | |
| 4lva | 20M | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.463 | |
| 5a3b | APR | SIR2 family protein | / | 0.463 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.462 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 1zmd | NAI | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.462 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.462 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.462 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.462 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.462 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.462 | |
| 4xwt | U5P | Ribonuclease J | / | 0.462 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.461 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.461 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 2cd8 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.461 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.461 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.461 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.461 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.461 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 3lam | KRP | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.461 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.461 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.461 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.460 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.460 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.460 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.460 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.460 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.460 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 2pnu | ENM | Androgen receptor | / | 0.460 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.460 | |
| 3beg | ANP | SRSF protein kinase 1 | 2.7.11.1 | 0.460 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.460 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.460 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.460 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.460 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 4g73 | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.460 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.460 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1c7o | PPG | Hemolysin | / | 0.459 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.459 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.459 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.459 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.459 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.459 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.459 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.459 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.459 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.459 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.459 | |
| 3zc3 | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.459 | |
| 4a32 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.459 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.459 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.459 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.459 | |
| 4nr4 | 2LK | CREB-binding protein | / | 0.459 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.458 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.458 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.458 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.458 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.458 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.458 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.458 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.458 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.458 | |
| 3g8e | IS1 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.458 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.458 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
| 4b13 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.458 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.458 | |
| 4lww | LWW | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.458 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.458 | |
| 5hi6 | MTX | Dihydrofolate reductase | / | 0.458 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.457 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2c6h | PXI | Cytochrome P450 monooxygenase PikC | / | 0.457 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.457 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.457 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 2y4g | TIR | TamL | / | 0.457 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.457 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.457 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.457 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.457 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4f4p | 0SB | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.457 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.457 | |
| 4kfp | 1R7 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.457 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.456 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.456 | |
| 2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.456 | |
| 2nn7 | M29 | Carbonic anhydrase 1 | 4.2.1.1 | 0.456 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.456 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.456 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.456 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 3eej | 53R | Uncharacterized protein | / | 0.456 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.456 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.456 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.456 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.456 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.456 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.456 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.456 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.455 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.455 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.455 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.455 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.455 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.455 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.455 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.455 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.455 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.455 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.455 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.455 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.455 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.455 | |
| 5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.455 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1m8h | 6NI | Nitric oxide synthase, inducible | 1.14.13.39 | 0.454 | |
| 1owm | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.454 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.454 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.454 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.454 | |
| 2y3r | TIR | TamL | / | 0.454 | |
| 3k6l | 2BB | Peptide deformylase | 3.5.1.88 | 0.454 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.454 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.454 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.454 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.454 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.454 | |
| 4feh | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.454 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.454 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.454 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.453 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1rrm | APR | Lactaldehyde reductase | 1.1.1.77 | 0.453 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.453 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.453 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.453 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.453 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.453 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.453 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.453 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.453 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.453 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.452 | |
| 1jmh | UMP | Thymidylate synthase | / | 0.452 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.452 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 2g2f | AGS | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.452 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.452 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.452 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.452 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.452 | |
| 3lnb | COA | N-acetyltransferase family protein | / | 0.452 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.452 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.452 | |
| 3td7 | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.452 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.452 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.452 | |
| 4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.452 | |
| 4v12 | POG | MaoC like domain protein | / | 0.452 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.451 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.451 | |
| 1rkd | ADP | Ribokinase | / | 0.451 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.451 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.451 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 2gci | MRR | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.451 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.451 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.451 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.451 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.451 | |
| 3m6i | NAD | L-arabinitol 4-dehydrogenase | 1.1.1.12 | 0.451 | |
| 3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.451 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.451 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.451 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.451 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.451 | |
| 4hw2 | 19H | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.451 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.451 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.451 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.451 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.450 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.450 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.450 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.450 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.450 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.450 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.450 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.450 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 3cgd | NAD | Coenzyme A disulfide reductase | / | 0.450 | |
| 3cge | NDP | Coenzyme A disulfide reductase | / | 0.450 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.450 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 3ras | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.450 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.450 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.450 | |
| 3w0s | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.450 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 4apu | A2K | Progesterone receptor | / | 0.450 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.450 | |
| 4m10 | ICD | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.450 | |
| 4neu | Q1A | Receptor-interacting serine/threonine-protein kinase 1 | 2.7.11.1 | 0.450 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.450 | |
| 4trj | 665 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.450 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.449 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.449 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2g97 | DGB | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.449 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.449 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2zyn | BCD | Periplasmic binding protein | / | 0.449 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.449 | |
| 3ict | COA | Coenzyme A disulfide reductase | / | 0.449 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.449 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.449 | |
| 3vvp | BNU | Uncharacterized protein | / | 0.449 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.449 | |
| 4e2b | FMN | Dehydrogenase | / | 0.449 | |
| 4pb2 | 5UD | Nucleoside permease | / | 0.449 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.449 | |
| 4zp0 | DXC | Multidrug transporter MdfA | / | 0.449 | |
| 5a3c | NAD | SIR2 family protein | / | 0.449 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.449 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.449 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.448 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.448 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1vzd | CB3 | Thymidylate synthase | / | 0.448 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.448 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.448 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.448 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.448 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.448 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2xsz | ATP | RuvB-like 2 | 3.6.4.12 | 0.448 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.448 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3gob | HXX | DdmC | / | 0.448 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.448 | |
| 3kp4 | MII | Transcriptional regulator TcaR | / | 0.448 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.448 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.448 | |
| 4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.448 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.448 | |
| 4kto | FAD | Putative isovaleryl-CoA dehydrogenase protein | / | 0.448 | |
| 4otp | ADP | Serine/threonine-protein kinase RIO1 | 2.7.11.1 | 0.448 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.448 | |
| 1bpj | UMP | Thymidylate synthase | / | 0.447 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.447 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.447 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 1rm4 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.447 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.447 | |
| 3cjf | SAV | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.447 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.447 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.447 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.447 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.447 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.447 | |
| 4h3c | 0YZ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.447 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 4iah | 1DX | Alr2278 protein | / | 0.447 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.447 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.447 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.447 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.447 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1dv2 | ATP | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 1err | RAL | Estrogen receptor | / | 0.446 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.446 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.446 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.446 | |
| 1xny | BTN | Propionyl-CoA carboxylase complex B subunit | / | 0.446 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.446 | |
| 2iyp | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.446 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.446 | |
| 2p15 | EZT | Estrogen receptor | / | 0.446 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.446 | |
| 2wpx | ACO | Orf14 | / | 0.446 | |
| 2xvw | 9NR | Serum albumin | / | 0.446 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.446 | |
| 3gqo | APR | Non-structural polyprotein | / | 0.446 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.446 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.446 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.446 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.446 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.446 | |
| 4jnc | 1LF | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.446 | |
| 4okx | 198 | Androgen receptor | / | 0.446 | |
| 4qa1 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.446 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 5iw5 | NMN | NADH pyrophosphatase | / | 0.446 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1m8g | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.445 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.445 | |
| 1ty9 | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.445 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.445 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.445 | |
| 2h12 | CMX | Citrate synthase | / | 0.445 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.445 | |
| 2xp2 | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.445 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.445 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.445 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.445 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.445 | |
| 3iel | U5P | Ribonuclease TTHA0252 | 3.1 | 0.445 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.445 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4jr5 | 1LS | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.445 | |
| 4qmn | DB8 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.445 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.445 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 5cms | APR | O-acetyl-ADP-ribose deacetylase | / | 0.445 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.444 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.444 | |
| 1tw2 | ERT | Carminomycin 4-O-methyltransferase DnrK | 2.1.1.292 | 0.444 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.444 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.444 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.444 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.444 | |
| 2vnh | FAD | NADPH:ferredoxin reductase | / | 0.444 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.444 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.444 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.444 | |
| 3cps | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3juh | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.444 | |
| 3r5z | F42 | Uncharacterized protein | / | 0.444 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.444 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.444 | |
| 4gnc | ASO | Regucalcin | 3.1.1.17 | 0.444 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.444 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 4u7w | NDP | MxaA | / | 0.444 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.444 | |
| 1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.443 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 1ikv | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 1jra | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.443 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1tdc | UMP | Thymidylate synthase | / | 0.443 | |
| 2eld | SAH | Diphthine synthase | / | 0.443 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.443 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.443 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.443 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.443 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.443 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.443 | |
| 3iw5 | DF3 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.443 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.443 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.443 | |
| 4a33 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.443 | |
| 4fz6 | 0VG | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.443 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.443 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.443 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.443 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.442 | |
| 1dnp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.442 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.442 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1osv | CHC | Bile acid receptor | / | 0.442 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.442 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.442 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.442 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2i0e | PDS | Protein kinase C beta type | 2.7.11.13 | 0.442 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.442 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.442 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.442 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 3anl | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.442 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.442 | |
| 3eem | 53V | Uncharacterized protein | / | 0.442 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.442 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.442 | |
| 3mfu | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.442 | |
| 3s1c | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.442 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.442 | |
| 3v5j | 0F2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.442 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.442 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.442 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.442 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.442 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.442 | |
| 4o28 | 1QS | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.442 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1hk4 | T44 | Serum albumin | / | 0.441 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.441 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.441 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.441 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.441 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.441 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.441 | |
| 3eek | 53S | Uncharacterized protein | / | 0.441 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.441 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.441 | |
| 3tdl | 11D | Serum albumin | / | 0.441 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.441 | |
| 3uib | SB2 | Putative mitogen-activated protein kinase | / | 0.441 | |
| 3w2w | ATP | CRISPR system Cmr subunit Cmr2 | / | 0.441 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.441 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4a95 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.441 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4cta | ATP | CinA-like protein | / | 0.441 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.441 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.441 | |
| 4jrv | KJV | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.441 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1fp1 | HCC | Isoliquiritigenin 2'-O-methyltransferase | / | 0.440 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.440 | |
| 1thy | UMP | Thymidylate synthase | / | 0.440 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2acw | UPG | Glycosyltransferase | / | 0.440 | |
| 2c6d | ANP | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.440 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.440 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.440 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.440 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2x6d | X6D | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.440 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.440 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2yj5 | ATP | Copper-transporting ATPase | / | 0.440 | |
| 3f7z | 34O | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.440 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.440 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.440 | |
| 3mk6 | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.440 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.440 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.440 | |
| 4dsg | FAD | Uncharacterized protein | / | 0.440 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4iae | 1DX | Alr2278 protein | / | 0.440 | |
| 4ihl | 1F5 | 14-3-3 protein zeta/delta | / | 0.440 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.440 | |
| 4kfo | 1QS | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.440 | |
| 4lts | LTS | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.440 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.440 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4xiv | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.440 |