Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3chs4BULeukotriene A-4 hydrolase3.3.2.6

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3chs4BULeukotriene A-4 hydrolase3.3.2.61.000
4rsyB3NLeukotriene A-4 hydrolase3.3.2.60.616
3fui812Leukotriene A-4 hydrolase3.3.2.60.603
3fuj00GLeukotriene A-4 hydrolase3.3.2.60.578
3ful52DLeukotriene A-4 hydrolase3.3.2.60.565
3fu5492Leukotriene A-4 hydrolase3.3.2.60.487
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.447
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.447
4xwtU5PRibonuclease J/0.447