sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 1.000 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.574 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.561 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.557 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.555 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.552 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.548 | |
| 3bzu | A21 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.542 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.535 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.526 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.510 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.506 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.500 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.485 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.482 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.479 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.474 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.473 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.469 | |
| 3up3 | XCA | aceDAF-12 | / | 0.467 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.463 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.461 | |
| 3tfq | 07M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.459 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.456 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.455 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.455 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.455 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.455 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.455 | |
| 1osv | CHC | Bile acid receptor | / | 0.454 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.454 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.452 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.452 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.451 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.451 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.451 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.451 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.450 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.449 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.449 | |
| 1kvo | OAP | Phospholipase A2, membrane associated | / | 0.448 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.447 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.446 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.445 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.445 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.445 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.445 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.445 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.445 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.443 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.442 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.442 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.442 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.442 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.442 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.441 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.441 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.441 | |
| 1fml | RTL | Retinol dehydratase | / | 0.440 |