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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3bsyACOUDP-N-acetylbacillosamine N-acetyltransferase2.3.1.203

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3bsyACOUDP-N-acetylbacillosamine N-acetyltransferase2.3.1.2031.000
1yhjR6CPyridoxal kinase2.7.1.350.535
3zoiM2WIsopenicillin N synthase1.21.3.10.523
3s41S41Glucokinase2.7.1.20.519
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.511
1xddAAYIntegrin alpha-L/0.510
3zkyWT4Isopenicillin N synthase1.21.3.10.507
1hb1OCVIsopenicillin N synthase1.21.3.10.506
4b4w9L9Bifunctional protein FolD/0.506
1oc1ASVIsopenicillin N synthase1.21.3.10.505
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.501
1bk0ACVIsopenicillin N synthase1.21.3.10.500
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.500
3up0D7SaceDAF-12/0.499
2y60M8FIsopenicillin N synthase1.21.3.10.498
1obnASVIsopenicillin N synthase1.21.3.10.497
1ygkRRCPyridoxal kinase2.7.1.350.497
1cqp803Integrin alpha-L/0.496
1qjfACSIsopenicillin N synthase1.21.3.10.496
1ygjRMCPyridoxal kinase2.7.1.350.496
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.496
2jb4A14Isopenicillin N synthase1.21.3.10.496
1o6qR17Squalene--hopene cyclase4.2.1.1290.494
4iaq2GM5-hydroxytryptamine receptor 1B/0.494
4ku5DCC3-oxoacyl-[ACP] synthase III/0.492
1hb3SCVIsopenicillin N synthase1.21.3.10.490
3h4vDVPPteridine reductase 11.5.1.330.490
4dhyS41Glucokinase2.7.1.20.490
1uzwCDHIsopenicillin N synthase1.21.3.10.489
2iviACWIsopenicillin N synthase1.21.3.10.489
2vbdV10Isopenicillin N synthase1.21.3.10.489
4bb3KKAIsopenicillin N synthase1.21.3.10.489
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.488
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.488
1t2cNAIL-lactate dehydrogenase1.1.1.270.487
2gvcFADThiol-specific monooxygenase1.14.130.487
1h35R01Squalene--hopene cyclase4.2.1.1290.486
4at0FADPossible succinate dehydrogenase/0.486
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.485
3qm4PN0Cytochrome P450 2D6/0.485
3vf60H6Glucokinase2.7.1.20.485
4d9eLCSD-cysteine desulfhydrase/0.485
4dvi2IWTankyrase-12.4.2.300.485
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.484
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.484
1w6hTITPlasmepsin-23.4.23.390.483
2gd2CAAProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.483
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.482
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.482
4g3jVNTLanosterol 14-alpha-demethylase/0.482
2zynBCDPeriplasmic binding protein/0.481
4jlk1NODeoxycytidine kinase2.7.1.740.481
4iarERM5-hydroxytryptamine receptor 1B/0.480
2bu9HFVIsopenicillin N synthase1.21.3.10.479
2uxoTACHTH-type transcriptional regulator TtgR/0.479
4ixd1HVIntegrin alpha-L/0.479
4m99ACOUDP-N-acetylgalactosaminyltransferase/0.479
1blzACVIsopenicillin N synthase1.21.3.10.478
1pq944BOxysterols receptor LXR-beta/0.478
1s3uTQDDihydrofolate reductase1.5.1.30.478
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.478
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.477
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.477
1mrqSTRAldo-keto reductase family 1 member C1/0.476
3nz2ACOHexapeptide-repeat containing-acetyltransferase/0.476
4rvgTYDD-mycarose 3-C-methyltransferase/0.476
2c92TP66,7-dimethyl-8-ribityllumazine synthase2.5.1.780.475
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.475
3zeiAWHO-acetylserine sulfhydrylase/0.475
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.475
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.475
1qiqACCIsopenicillin N synthase1.21.3.10.474
1zdwFLVPrenyltransferase/0.474
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.474
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.474
3p3zP3ZPutative cytochrome P450/0.474
3qe2FMNNADPH--cytochrome P450 reductase/0.474
4jlj1NMDeoxycytidine kinase2.7.1.740.474
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.474
1pqc444Oxysterols receptor LXR-beta/0.473
2fxuBIDActin, alpha skeletal muscle/0.473
2zbaZBATrichothecene 3-O-acetyltransferase/0.473
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.473
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.472
2f3815MAldo-keto reductase family 1 member C3/0.472
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.472
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.472
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.472
3zcnATPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.472
4ixc1JDGlucokinase2.7.1.20.472
5uviZMAAdenosine receptor A2a/0.472
1g6oADPCag alpha/0.471
1ja0FMNNADPH--cytochrome P450 reductase/0.471
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.471
3l77NJPShort-chain alcohol dehydrogenase/0.471
4n4v2GYTankyrase-12.4.2.300.471
4phlPILPhosphodiesterase/0.471
1rf7DHFDihydrofolate reductase1.5.1.30.470
2vcmM11Isopenicillin N synthase1.21.3.10.470
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.470
3oafOAGDihydrofolate reductase1.5.1.30.470
4bfuZVUPantothenate kinase2.7.1.330.470
1o6rR19Squalene--hopene cyclase4.2.1.1290.469
1ry0PG2Aldo-keto reductase family 1 member C3/0.469
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.469
3gncQQQGlutaryl-CoA dehydrogenase/0.469
3nx4NAPPutative oxidoreductase/0.469
3pefNAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase/0.469
5c3jFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.469
5k2dZMAAdenosine receptor A2a/0.469
1uyhPU0Heat shock protein HSP 90-alpha/0.468
1w06W05Isopenicillin N synthase1.21.3.10.468
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.468
2ntjP1HEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.468
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.468
3rkuNAPNADP-dependent 3-hydroxy acid dehydrogenase/0.468
3vtbTKAVitamin D3 receptor/0.468
3zkuHCVIsopenicillin N synthase1.21.3.10.468
4az3S35Lysosomal protective protein3.4.16.50.468
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.468
4s1iPLPPyridoxal kinase, putative/0.468
5dbfNDPIridoid synthase1.3.1.990.468
5k2cZMAAdenosine receptor A2a/0.468
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.467
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.467
2wo7ASVIsopenicillin N synthase1.21.3.10.467
3wv9FEGHmd co-occurring protein HcgE/0.467
4b4vL34Bifunctional protein FolD/0.467
5iu86DZAdenosine receptor A2a/0.467
3emlZMAAdenosine receptor A2a/0.467
1g63FMNEpidermin decarboxylase4.1.10.466
1h36R88Squalene--hopene cyclase4.2.1.1290.466
1lf2R37Plasmepsin-23.4.23.390.466
1rd4L08Integrin alpha-L/0.466
1vf3GDNGlutathione S-transferase 32.5.1.180.466
2bfmTOPPteridine reductase 11.5.1.330.466
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.466
2o7pNAPRiboflavin biosynthesis protein RibD/0.466
2x6o2TCTetracycline repressor protein class D/0.466
2y6fM9FIsopenicillin N synthase1.21.3.10.466
2ydoADNAdenosine receptor A2a/0.466
3qwbNDPProbable quinone oxidoreductase1.6.5.50.466
3vtdTKDVitamin D3 receptor/0.466
4nwiCTN7-methylguanosine phosphate-specific 5'-nucleotidase/0.466
5jtbZMAAdenosine receptor A2a/0.466
1disBDMDihydrofolate reductase1.5.1.30.465
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.465
1wp4NDP3-hydroxyisobutyrate dehydrogenase/0.465
2cy2ACOProbable acetyltransferase/0.465
2fhjH4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.465
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.465
3imxB84Glucokinase2.7.1.20.465
4ytnFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.465
5kf9ACOPredicted acetyltransferase/0.465
1xg5NAPDehydrogenase/reductase SDR family member 11/0.464
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.464
2ntvP1HEnoyl-[acyl-carrier-protein] reductase [NADH]/0.464
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.464
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.464
2yimMC4Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.464
3h3qH13Collagen type IV alpha-3-binding protein/0.464
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.464
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
4ej1FOLDihydrofolate reductase1.5.1.30.464
4r20AERCytochrome P450 family 17 polypeptide 2/0.464
1e6eFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.463
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.463
2rd2QSIGlutamine--tRNA ligase6.1.1.180.463
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.463
3aosJH2Hemolymph juvenile hormone binding protein/0.463
4iwv1J9Glucokinase2.7.1.20.463
5g53NECAdenosine receptor A2a/0.463
5k2bZMAAdenosine receptor A2a/0.463
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.462
2a94AP0L-lactate dehydrogenase1.1.1.270.462
2gd6ACOProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.462
2j9lATPH(+)/Cl(-) exchange transporter 5/0.462
3eon341Glutaryl-CoA dehydrogenase/0.462
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.462
3ghvGHCDihydrofolate reductase1.5.1.30.462
3l0lHC3Nuclear receptor ROR-gamma/0.462
3upyFOMOxidoreductase, putative/0.462
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
4eiyZMAAdenosine receptor A2a/0.462
5irnADPNucleotide binding oligomerization domain containing 2/0.462
1p8dCO1Oxysterols receptor LXR-beta/0.461
1pz1NAPGeneral stress protein 69/0.461
1yc2NADNAD-dependent protein deacylase 2/0.461
2e48FADD-amino-acid oxidase1.4.3.30.461
2po7CHDFerrochelatase, mitochondrial4.99.1.10.461
2r6jNDPEugenol synthase 11.1.1.3180.461
3a1l2CCCytochrome P450/0.461
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.461
3hkyIX6Genome polyprotein2.7.7.480.461
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.461
3pduNAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase/0.461
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.461
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.460
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.460
2zevB71Geranylgeranyl pyrophosphate synthase/0.460
3f63GTXGlutathione transferase GST1-4/0.460
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.460
4bfvZVVPantothenate kinase2.7.1.330.460
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.460
1c7oPPGHemolysin/0.459
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.459
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.459
1uy9PU6Heat shock protein HSP 90-alpha/0.459
3br9DEYGenome polyprotein2.7.7.480.459
3ds6A17Mitogen-activated protein kinase 14/0.459
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
3ol5SAWCamphor 5-monooxygenase1.14.15.10.459
3q44D50M1 family aminopeptidase3.4.110.459
4c0bATPmRNA cleavage and polyadenylation factor CLP1/0.459
4exg916Beta-secretase 13.4.23.460.459
4mka2AYGenome polyprotein2.7.7.480.459
4ubtCOASteroid 3-ketoacyl-CoA thiolase/0.459
5hs1VORLanosterol 14-alpha demethylase/0.459
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.458
1x8lOXRRetinol dehydratase/0.458
1xkdNAPIsocitrate dehydrogenase [NADP]/0.458
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2b58COADiamine acetyltransferase 1/0.458
3gw9VNILanosterol 14-alpha-demethylase/0.458
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.458
3tdaPN0Cytochrome P450 2D6/0.458
4eaw0NQGenome polyprotein2.7.7.480.458
4g95OAGDihydrofolate reductase1.5.1.30.458
4h6pFMNChromate reductase/0.458
2geuCOKPantothenate kinase2.7.1.330.457
2rqfJH3Hemolymph juvenile hormone binding protein/0.457
2vbpVB1Isopenicillin N synthase1.21.3.10.457
3igvB80Genome polyprotein2.7.7.480.457
3ix8TX3Transcriptional activator protein LasR/0.457
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3qpg3QPAspartate aminotransferase2.6.1.10.457
3vg9ZMAAdenosine receptor A2a/0.457
4a81DXCMajor pollen allergen Bet v 1-A/0.457
4e2yJHZMethyltransferase/0.457
4jlm1NNDeoxycytidine kinase2.7.1.740.457
5iubCLRAdenosine receptor A2a/0.457
5kgjACOPredicted acetyltransferase/0.457
1o8cNDPProbable acrylyl-CoA reductase AcuI1.3.1.840.456
1rpwDIDHTH-type transcriptional regulator QacR/0.456
1s7gNADNAD-dependent protein deacylase 2/0.456
1upw444Oxysterols receptor LXR-beta/0.456
2nn7M29Carbonic anhydrase 14.2.1.10.456
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.456
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.456
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
4bkjSTIEpithelial discoidin domain-containing receptor 12.7.10.10.456
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.456
4lb2DM5Serum albumin/0.456
4y0kNAPAntE/0.456
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.455
1iyzNDPProbable quinone oxidoreductase/0.455
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
1tfz8694-hydroxyphenylpyruvate dioxygenase1.13.11.270.455
1txzAPRProbable ADP-ribose 1''-phosphate phosphatase YML087W3.1.3.840.455
1u1d181Uridine phosphorylase2.4.2.30.455
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.455
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.455
2q4wFADCytokinin dehydrogenase 71.5.99.120.455
2vkmBSDBeta-secretase 13.4.23.460.455
2xlpNAPPutative flavin-containing monooxygenase/0.455
3exnACOProbable acetyltransferase/0.455
3h3r14HCollagen type IV alpha-3-binding protein/0.455
3in6FMNUncharacterized protein/0.455
3q9bB3NAcetylpolyamine amidohydrolase/0.455
4a83DXCMajor pollen allergen Bet v 1-A/0.455
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.455
4ubuCOASteroid 3-ketoacyl-CoA thiolase/0.455
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.455
5ctoNTD4-hydroxyphenylpyruvate dioxygenase1.13.11.270.455
1al8DHPPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.454
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.454
1mbzIOTCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.454
1mvsDTMDihydrofolate reductase1.5.1.30.454
1ogiFADFerredoxin--NADP reductase1.18.1.20.454
1pu9COAHAT A1/0.454
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.454
2fzwNADAlcohol dehydrogenase class-31.1.1.10.454
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.454
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.454
3zkpERBErythromycin C-12 hydroxylase1.14.13.1540.454
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.454
4dlcUMPDeoxyuridine triphosphatase, putative/0.454
4h3f10OBeta-secretase 13.4.23.460.454
4kxjP34Nucleoprotein/0.454
5iua6DXAdenosine receptor A2a/0.454
1jomFFODihydrofolate reductase1.5.1.30.453
1tg56454-hydroxyphenylpyruvate dioxygenase1.13.11.270.453
2bi4NADLactaldehyde reductase1.1.1.770.453
2flhZEACytokinin-specific binding protein/0.453
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.453
2jf6S55Strictosidine-O-beta-D-glucosidase3.2.1.1050.453
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
3bgxMEFThymidylate synthase/0.453
3ekuCY9Actin-5C/0.453
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
3hqdANPKinesin-like protein KIF11/0.453
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.453
3ogwIMNLactoperoxidase1.11.1.70.453
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.453
4l5b1UXDeoxycytidine kinase2.7.1.740.453
4mk928RGenome polyprotein2.7.7.480.453
1diuBDMDihydrofolate reductase1.5.1.30.452
1fmjRTLRetinol dehydratase/0.452
1id0ANPSensor protein PhoQ2.7.13.30.452
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.452
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.452
2gpvOHTEstrogen-related receptor gamma/0.452
2ym1FADPhenylacetone monooxygenase1.14.13.920.452
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.452
3eigMTXDihydrofolate reductase1.5.1.30.452
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.452
3lfcZ86Mitogen-activated protein kinase 14/0.452
3slkNDPPolyketide synthase extender module 2/0.452
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
4ia1BIVVitamin D3 receptor A/0.452
4q0kGA3Phytohormone-binding protein/0.452
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.452
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.452
1pq6965Oxysterols receptor LXR-beta/0.451
1ypeUIPProthrombin3.4.21.50.451
2getCOKPantothenate kinase2.7.1.330.451
2r2mI50Prothrombin3.4.21.50.451
2vn1FK5Peptidylprolyl isomerase/0.451
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
3h3t16HCollagen type IV alpha-3-binding protein/0.451
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.451
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
3ndjJHZMethyltransferase/0.451
3ox4NADAlcohol dehydrogenase 21.1.1.10.451
3qlrNDPDihydrofolate reductase1.5.1.30.451
3sf6FDAGlutaryl-CoA dehydrogenase/0.451
3t3r9PLCytochrome P450 2A61.14.130.451
4bftZVTPantothenate kinase2.7.1.330.451
4bfxZVXPantothenate kinase2.7.1.330.451
4dpf0LGBeta-secretase 13.4.23.460.451
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
5a2yUTPMitochondrial poly(A) polymerase/0.451
5kf8ACOPredicted acetyltransferase/0.451
5k2aZMAAdenosine receptor A2a/0.451
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.450
1pd9CO4Dihydrofolate reductase1.5.1.30.450
1pt8ACOFormyl-CoA:oxalate CoA-transferase/0.450
1tlcF89Thymidylate synthase/0.450
1txtCAAHMG-CoA synthase/0.450
1tysDHFThymidylate synthase/0.450
1wl4COAAcetyl-CoA acetyltransferase, cytosolic2.3.1.90.450
2du8FADD-amino-acid oxidase1.4.3.30.450
3gkjHC3Niemann-Pick C1 protein/0.450
3v94WYQPhosphodiesterase/0.450
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.450
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.450
4ryvZEAProtein LlR18A/0.450
1mewXMPInosine-5'-monophosphate dehydrogenase/0.449
1obbNADAlpha-glucosidase3.2.1.200.449
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.449
1uydPU8Heat shock protein HSP 90-alpha/0.449
1yinCM3Estrogen receptor/0.449
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.449
2dhfDZFDihydrofolate reductase1.5.1.30.449
2fwyH64Heat shock protein HSP 90-alpha/0.449
2npiATPmRNA cleavage and polyadenylation factor CLP1/0.449
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2q7hYLYPyrrolysine--tRNA ligase/0.449
2wf0ZY0Beta-secretase 13.4.23.460.449
3fhxPLPPyridoxal kinase2.7.1.350.449
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
3hl0NADMaleylacetate reductase/0.449
3n62XFJNitric oxide synthase, brain1.14.13.390.449
3s3vTOPDihydrofolate reductase1.5.1.30.449
3up3XCAaceDAF-12/0.449
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.449
4oztP1AEcdysone receptor, putative/0.449
4u9vACON-alpha-acetyltransferase 402.3.10.449
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.449
1mvtDTMDihydrofolate reductase1.5.1.30.448
1p33MTXPteridine reductase 11.5.1.330.448
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1uy8PU5Heat shock protein HSP 90-alpha/0.448
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.448
2hpsCTZCa2+-triggered coelenterazine-binding protein 1/0.448
2idkC2FGlycine N-methyltransferase2.1.1.200.448
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.448
2qx7NAPEugenol synthase 11.1.1.3180.448
2re8GSUGlutamine--tRNA ligase6.1.1.180.448
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.448
3bg7FADPyranose 2-oxidase/0.448
3csoXNIGenome polyprotein2.7.7.480.448
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.448
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.448
3fwjCAMCamphor 5-monooxygenase1.14.15.10.448
3gkiCLRNiemann-Pick C1 protein/0.448
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3p67FMNPentaerythritol tetranitrate reductase/0.448
3t88S0N1,4-dihydroxy-2-naphthoyl-CoA synthase/0.448
3tfyCOAN-alpha-acetyltransferase 502.3.10.448
3toxNAPPutative oxidoreductase/0.448
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.448
4bfwZVWPantothenate kinase2.7.1.330.448
4bj9UHBTankyrase-22.4.2.300.448
4dpi0N1Beta-secretase 13.4.23.460.448
4elf35IDihydrofolate reductase/0.448
4fsa0V3Queuine tRNA-ribosyltransferase2.4.2.290.448
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.448
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.448
4jl6ADPAdenylate kinase/0.448
4jv41ORcAMP-dependent protein kinase type I-alpha regulatory subunit/0.448
4k8s1QTBeta-secretase 13.4.23.460.448
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.448
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.448
4xnhACON-terminal acetyltransferase A complex subunit NAT52.3.10.448
1drfFOLDihydrofolate reductase1.5.1.30.447
1hfqMOTDihydrofolate reductase1.5.1.30.447
1pt5ACOFormyl-CoA:oxalate CoA-transferase/0.447
1w29TS06,7-dimethyl-8-ribityllumazine synthase2.5.1.780.447
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
1zgv501Prothrombin3.4.21.50.447
2cv2GSUGlutamate--tRNA ligase6.1.1.170.447
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.447
2lfoGCHFatty acid-binding protein, liver/0.447
2o7oDXTTetracycline repressor protein class D/0.447
3abaFLICytochrome P450/0.447
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.447
3ixj586Beta-secretase 13.4.23.460.447
3nhpHGZRibosyldihydronicotinamide dehydrogenase [quinone]/0.447
4b5oACOAlpha-tubulin N-acetyltransferase 1/0.447
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.447
4g48PZBMycocyclosin synthase1.14.21.90.447
4g7gVFVLanosterol 14-alpha-demethylase/0.447
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
4j7uNAPSepiapterin reductase1.1.1.1530.447
4u2lSFDCholesterol oxidase1.1.3.60.447
4x8lAP5Adenylate kinase/0.447
4x9dU5PUncharacterized protein MJ1435/0.447
4yfy0FXVioF/0.447
5jscFADPutative acyl-CoA dehydrogenase/0.447
1jnzFADAdenylylsulfate reductase, subunit A (AprA)/0.446
1qvuPRLHTH-type transcriptional regulator QacR/0.446
1s9dAFBCytohesin-2/0.446
1s9dAFBADP-ribosylation factor 1/0.446
1szcCNANAD-dependent protein deacetylase HST23.5.10.446
2e9dB76Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.446
2vijC44Beta-secretase 13.4.23.460.446
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.446
3nu03TUDihydrofolate reductase1.5.1.30.446
4bfsZVSPantothenate kinase2.7.1.330.446
4bfzZVZPantothenate kinase2.7.1.330.446
4fevPP1Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.446
4n1gCEIObelin/0.446
4rphGDUUDP-galactopyranose mutase5.4.99.90.446
5bp9SAHPutative methyltransferase protein/0.446
5kf2ACOPredicted acetyltransferase/0.446
1d3pBT3Prothrombin3.4.21.50.445
1h69ARHNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1mjaCOAHistone acetyltransferase ESA1/0.445
1ndzFR5Adenosine deaminase3.5.4.40.445
1o97FADElectron transfer flavoprotein subunit alpha/0.445
1rf9DBRCamphor 5-monooxygenase1.14.15.10.445
1rvvINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.445
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.445
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.445
2culFADGidA-related protein/0.445
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.445
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.445
2jdcCAOProbable acetyltransferase/0.445
2jddACOProbable acetyltransferase/0.445
2pswCOAN-alpha-acetyltransferase 50/0.445
2xveFADPutative flavin-containing monooxygenase/0.445
3jynNDPQuinone oxidoreductase/0.445
3qbhQBHBeta-secretase 13.4.23.460.445
4a6rTA8Probable aminotransferase/0.445
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
4e2xTYDMethyltransferase/0.445
4o9cCOAAcetyl-CoA acetyltransferase2.3.1.90.445
4yaoFMNNADPH--cytochrome P450 reductase/0.445
4zowCLMMultidrug transporter MdfA/0.445
5dbgNADIridoid synthase1.3.1.990.445
5fd8A5APutative carboxypeptidase yocD/0.445
5fkmTDCTetracycline repressor protein class D/0.445
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.445
1a4iNDPC-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.444
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.444
1xp8AGSProtein RecA/0.444
1zg32HIIsoflavone 4'-O-methyltransferase/0.444
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.444
2e0iFADDNA photolyase/0.444
2gv8NDPThiol-specific monooxygenase1.14.130.444
2rgxAP5Adenylate kinase/0.444
2ym1NAPPhenylacetone monooxygenase1.14.13.920.444
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.444
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
3g70A5TRenin3.4.23.150.444
3ghh2NFCD38 molecule/0.444
3ou2SAHSAM-dependent methyltransferase/0.444
3pqbVGPPutative oxidoreductase/0.444
3uk6ADPRuvB-like 23.6.4.120.444
3vwdACOAlpha-tubulin N-acetyltransferase 1/0.444
4da6GA2Purine nucleoside phosphorylase DeoD-type2.4.2.10.444
4dbc3QPAspartate aminotransferase2.6.1.10.444
4dch4DCGlucokinase2.7.1.20.444
4e2zJHZMethyltransferase/0.444
4e32DWNMethyltransferase/0.444
4e37NDPCatalase1.11.1.60.444
4ead0NPThymidine phosphorylase2.4.2.40.444
4gr9372Ribosyldihydronicotinamide dehydrogenase [quinone]/0.444
4hx519VCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
4jtqNAPAldo-keto reductase family 1 member C2/0.444
4k6fNAPPutative Acetoacetyl-CoA reductase/0.444
4kak06UDihydrofolate reductase1.5.1.30.444
4pnmNU1Tankyrase-22.4.2.300.444
4twnB96Ephrin type-A receptor 32.7.10.10.444
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.444
4xbjIN5Alanine racemase, biosynthetic/0.444
5f8eSAHPossible transcriptional regulatory protein/0.444
1e2nRCAThymidine kinase/0.443
1fcx184Retinoic acid receptor gamma/0.443
1mp0NADAlcohol dehydrogenase class-31.1.1.10.443
1ne6SP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.443
1oo6SN2Oxygen-insensitive NAD(P)H nitroreductase/0.443
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.443
1tkaN3TTransketolase 12.2.1.10.443
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.443
1wn3HXCPhenylacetic acid degradation protein PaaI/0.443
1xuoLA1Integrin alpha-L/0.443
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2b4yAPRNAD-dependent protein deacylase sirtuin-5, mitochondrial/0.443
2belCBOCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
2e0nSAHPrecorrin-2 C20-methyltransferase/0.443
2e95B75Geranylgeranyl pyrophosphate synthase/0.443
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
2stdCRPScytalone dehydratase4.2.1.940.443
2vkeTACTetracycline repressor protein class D/0.443
3axbFADPutative oxidoreductase/0.443
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.443
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.443
3kpkFADSulfide-quinone reductase/0.443
3vqrFADPutative oxidoreductase/0.443
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.443
4b78KGGBeta-secretase 13.4.23.460.443
4dz5NAPAldo-keto reductase family 1 member C3/0.443
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.443
4glx0XSDNA ligase6.5.1.20.443
4qx5CMPcGMP-dependent protein kinase 12.7.11.120.443
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.443
4zm6ACON-acetyl-beta-D glucosaminidase/0.443
5kf1COAPredicted acetyltransferase/0.443
5stdUNNScytalone dehydratase4.2.1.940.443
3uzcT4EAdenosine receptor A2a/0.443
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.442
1ta6177Prothrombin3.4.21.50.442
1xdsDRAAclacinomycin 10-hydroxylase RdmB4.1.10.442
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.442
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.442
2ohiFMNType A flavoprotein FprA10.442
2vxkCOAGlucosamine 6-phosphate acetyltransferase, putative/0.442
2z3uCRRCytochrome P450/0.442
3fsjD7KBenzoylformate decarboxylase4.1.1.70.442
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.442
3h3sH15Collagen type IV alpha-3-binding protein/0.442
3i0pNADMalate dehydrogenase, putative/0.442
3n5xXFKNitric oxide synthase, brain1.14.13.390.442
3qeoLLTDeoxycytidine kinase2.7.1.740.442
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.442
3uph0C1Genome polyprotein2.7.7.480.442
3znpFADD-amino-acid oxidase1.4.3.30.442
4jq3NAPAldo-keto reductase family 1 member C2/0.442
4nh82LCHeat shock protein HSP 90-alpha/0.442
4uymVOR14-alpha sterol demethylase Cyp51B/0.442
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.442
1dhfFOLDihydrofolate reductase1.5.1.30.441
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.441
1kf6FADFumarate reductase flavoprotein subunit1.3.5.40.441
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
1pkfEPDEpothilone C/D epoxidase1.140.441
1r8qAFBCytohesin-2/0.441
1r8qAFBADP-ribosylation factor 1/0.441
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.441
2gciMRRProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.441
2rgjFADFlavin-containing monooxygenase/0.441
2v6gNAP3-oxo-Delta(4,5)-steroid 5-beta-reductase/0.441
2vn0TDZCytochrome P450 2C8/0.441
2y01Y00Beta-1 adrenergic receptor/0.441
2zymACXPeriplasmic binding protein/0.441
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.441
3d3wNAPL-xylulose reductase1.1.1.100.441
3h59H59Genome polyprotein2.7.7.480.441
3t5iSER_SER_CMT_FARRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.441
3wixLC3Induced myeloid leukemia cell differentiation protein Mcl-1/0.441
4b7754MBeta-secretase 13.4.23.460.441
4jl5ADPAdenylate kinase/0.441
4kwhNAPReductase homolog/0.441
4la0198Serum albumin/0.441
4lv5ADPRhoptry protein 5B/0.441
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.441
4xo7NAPAldo-keto reductase family 1 member C2/0.441
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.441
1e1nFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.440
1e1qADPATP synthase subunit beta, mitochondrial3.6.3.140.440
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.440
1jf2CZHObelin/0.440
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.440
1ra3NAPDihydrofolate reductase1.5.1.30.440
2g274LGRenin3.4.23.150.440
2givACOHistone acetyltransferase KAT8/0.440
2hasC3OVitamin D3 receptor/0.440
2nmtNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.440
2pamTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.440
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.440
2x9dITCTetracycline repressor protein class D/0.440
2ym2NAPPhenylacetone monooxygenase1.14.13.920.440
2zu8GDDMannosyl-3-phosphoglycerate synthase2.4.1.2170.440
3d7zGK5Mitogen-activated protein kinase 14/0.440
3hu1AGSTransitional endoplasmic reticulum ATPase3.6.4.60.440
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3n0hTOPDihydrofolate reductase1.5.1.30.440
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.440
3p99LNPLanosterol 14-alpha-demethylase/0.440
3qiyQI1Botulinum neurotoxin type A3.4.24.690.440
3tn7NJPShort-chain alcohol dehydrogenase/0.440
3u2mFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.440
4b1rITCTetracycline repressor protein class D/0.440
4bfyZVYPantothenate kinase2.7.1.330.440
4g1z0VPVitamin D3 receptor A/0.440
4gtv7TRGeranylgeranyl transferase type-2 subunit beta2.5.1.600.440
4hy6FJ1Heat shock protein HSP 90-alpha/0.440
4i0h1BLBeta-secretase 13.4.23.460.440
4i1nFOLDihydrofolate reductase1.5.1.30.440
4j491J1Uncharacterized protein/0.440
4j6bPLOCytochrome P450 monooxygenase/0.440
4o701QKBromodomain-containing protein 4/0.440
4qbiAP5Adenylate kinase/0.440
4rujVDXVitamin D3 receptor A/0.440
4v2gCTCTetracycline repressor protein class D/0.440