sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3bk2 | U5P | Ribonuclease J |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3bk2 | U5P | Ribonuclease J | / | 1.000 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.458 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.454 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.452 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.452 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.448 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.448 | |
| 4xwt | U5P | Ribonuclease J | / | 0.448 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.447 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.446 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.446 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.442 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.441 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.441 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.440 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 |