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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3b8hNADExotoxin A2.4.2.36

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3b8hNADExotoxin A2.4.2.361.000
2zitNADExotoxin A2.4.2.360.607
3b82NADExotoxin A2.4.2.360.574
3b78NADExotoxin A2.4.2.360.565
1zm4TADExotoxin A2.4.2.360.497
4tkg09LTankyrase-22.4.2.300.479
5dsyUHBPoly [ADP-ribose] polymerase 22.4.2.300.470
4bj9UHBTankyrase-22.4.2.300.459
1dtpAPUDiphtheria toxin/0.452
1ddtAPUDiphtheria toxin/0.446
4tvj09LPoly [ADP-ribose] polymerase 22.4.2.300.442