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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3a62STURibosomal protein S6 kinase beta-12.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3a62STURibosomal protein S6 kinase beta-12.7.11.11.000
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.581
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.563
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.558
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.558
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.558
2hog710Serine/threonine-protein kinase Chk12.7.11.10.557
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.557
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.556
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.556
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.551
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.549
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.547
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.547
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.546
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.545
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.544
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.544
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.544
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.543
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.543
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.543
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.542
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.541
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.541
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.541
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.536
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.535
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.535
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.535
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.534
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.534
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.533
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.531
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.530
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.530
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.529
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.529
1wvxBD4Death-associated protein kinase 12.7.11.10.528
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.528
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.528
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.527
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.527
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.526
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.525
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.524
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.523
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.522
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.521
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.520
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.520
2ckeIQUDeath-associated protein kinase 2/0.520
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.517
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.517
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.516
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.516
3t8oATPRhodopsin kinase/0.516
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.515
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.515
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.514
1zrzBI1Protein kinase C iota type2.7.11.130.514
4bcmT7ZCyclin-dependent kinase 22.7.11.220.513
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.513
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.512
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.511
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.511
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.511
3sheI85MAP kinase-activated protein kinase 32.7.11.10.510
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.510
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.510
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.509
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.509
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.509
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.509
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.508
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.507
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.507
3zh8C58Protein kinase C iota type2.7.11.130.507
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.505
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.504
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.503
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.503
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.503
3gubGUBDeath-associated protein kinase 12.7.11.10.503
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.503
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.503
4fob0USALK tyrosine kinase receptor2.7.10.10.503
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.503
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.502
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.502
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.501
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.501
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.501
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.501
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.500
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.500
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.500
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.499
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.499
3eb0DRKUncharacterized protein/0.499
4b99R4LMitogen-activated protein kinase 72.7.11.240.499
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.499
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.498
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.498
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.498
4wboANWRhodopsin kinase/0.498
2j0m4STFocal adhesion kinase 12.7.10.20.497
3igoANPCalmodulin-domain protein kinase 1, putative/0.497
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.497
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.496
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.496
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.496
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.496
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.496
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.496
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.496
5dr9SKEAurora kinase A2.7.11.10.496
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.495
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.495
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.495
1g5sI17Cyclin-dependent kinase 22.7.11.220.494
3bqr4RBDeath-associated protein kinase 3/0.494
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.494
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.493
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.493
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.493
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.493
1fvv107Cyclin-dependent kinase 22.7.11.220.492
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.492
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.492
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.492
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.492
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.491
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.491
4hvh19RTyrosine-protein kinase JAK32.7.10.20.491
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.490
4fv6E57Mitogen-activated protein kinase 12.7.11.240.490
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.490
1aq1STUCyclin-dependent kinase 22.7.11.220.489
2vd5BI8Myotonin-protein kinase2.7.11.10.489
2wxvWXVCyclin-dependent kinase 22.7.11.220.489
4c62XWWTyrosine-protein kinase JAK2/0.489
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.489
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.489
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.488
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.488
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.488
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.488
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.488
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
3bhy7CPDeath-associated protein kinase 3/0.488
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.488
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.488
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.488
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.487
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.487
4fv9E71Mitogen-activated protein kinase 12.7.11.240.487
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.486
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.486
3zewSTUEphrin type-B receptor 42.7.10.10.486
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.486
4cd0AWJALK tyrosine kinase receptor2.7.10.10.486
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.486
4gk2L66Ephrin type-A receptor 32.7.10.10.486
5auwQUEDeath-associated protein kinase 12.7.11.10.486
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.485
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.485
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.485
2w05FRTCyclin-dependent kinase 22.7.11.220.485
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.485
3c4xATPRhodopsin kinase/0.485
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.485
3nynSGVG protein-coupled receptor kinase 62.7.11.160.485
4hvg19QTyrosine-protein kinase JAK32.7.10.20.485
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.485
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.484
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.484
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.483
1xjdSTUProtein kinase C theta type2.7.11.130.483
1yvj4STTyrosine-protein kinase JAK32.7.10.20.483
2vv9IM9Cyclin-dependent kinase 22.7.11.220.483
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.483
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.483
5av2KMPDeath-associated protein kinase 12.7.11.10.483
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.482
1zys199Serine/threonine-protein kinase Chk12.7.11.10.482
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.482
3ezrEZRCyclin-dependent kinase 22.7.11.220.482
3gu6ADPDeath-associated protein kinase 12.7.11.10.482
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.482
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.482
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.482
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.482
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.482
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.481
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.481
2x6dX6DAurora kinase A2.7.11.10.481
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.481
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.481
4o0wADNAurora kinase A2.7.11.10.481
5aaaVGHALK tyrosine kinase receptor2.7.10.10.481
2ijmADPFocal adhesion kinase 12.7.10.20.479
2x1nX1NCyclin-dependent kinase 22.7.11.220.479
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.479
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.479
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.479
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.479
4hvi19STyrosine-protein kinase JAK32.7.10.20.479
4jia1K3Tyrosine-protein kinase JAK2/0.479
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.479
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.479
5dt0SKEAurora kinase A2.7.11.10.479
2j0lANPFocal adhesion kinase 12.7.10.20.478
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.478
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.478
1u54ACPActivated CDC42 kinase 1/0.477
1wvySTUDeath-associated protein kinase 12.7.11.10.477
2yaaATPDeath-associated protein kinase 2/0.477
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.477
3i60E86Mitogen-activated protein kinase 12.7.11.240.477
4foc0UUALK tyrosine kinase receptor2.7.10.10.477
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.477
5av4GENDeath-associated protein kinase 12.7.11.10.477
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.476
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
3s2pPMUCyclin-dependent kinase 22.7.11.220.476
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.476
4yuqKS1Calmodulin-like domain protein kinase/0.476
2xb7GUIALK tyrosine kinase receptor2.7.10.10.475
3eyhIZATyrosine-protein kinase JAK1/0.475
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.475
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.475
4bgh3I6Cyclin-dependent kinase 22.7.11.220.475
4c61LMMTyrosine-protein kinase JAK2/0.475
2vu3LZECyclin-dependent kinase 22.7.11.220.474
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.474
3sqq99ZCyclin-dependent kinase 22.7.11.220.474
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.474
4ks7X4ZSerine/threonine-protein kinase PAK 62.7.11.10.474
1pkdUCNCyclin-dependent kinase 22.7.11.220.473
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.473
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.473
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.473
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.473
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.472
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.472
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.472
2yn8STUEphrin type-B receptor 42.7.10.10.472
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.472
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.472
4f640S8Fibroblast growth factor receptor 1/0.472
4l9i8PRRhodopsin kinase/0.472
1gih1PUCyclin-dependent kinase 22.7.11.220.471
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.471
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.471
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.471
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.471
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.471
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
1h1r6CPCyclin-dependent kinase 22.7.11.220.470
2i40BLZCyclin-dependent kinase 22.7.11.220.470
2in6839Wee1-like protein kinase2.7.10.20.470
2ojj82AMitogen-activated protein kinase 12.7.11.240.470
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.470
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.470
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.470
4fx360KCyclin-dependent kinase 22.7.11.220.470
5auvAGIDeath-associated protein kinase 12.7.11.10.470
3rkb12ZCyclin-dependent kinase 22.7.11.220.469
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.469
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.469
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.469
5e8xSTUTGF-beta receptor type-12.7.11.300.469
1dq8COA3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.468
1oiyN41Cyclin-dependent kinase 22.7.11.220.468
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.468
4ic7ANPMitogen-activated protein kinase 72.7.11.240.468
5auxKMPDeath-associated protein kinase 12.7.11.10.468
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
2etm7PYFocal adhesion kinase 12.7.10.20.467
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
2yac937Serine/threonine-protein kinase PLK12.7.11.210.467
3lltANPProtein serine/threonine kinase-1/0.467
3qc9ADPRhodopsin kinase/0.467
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.467
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.467
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.466
3zep1NXTyrosine-protein kinase JAK32.7.10.20.466
4bcqTJFCyclin-dependent kinase 22.7.11.220.466
4erwSTUCyclin-dependent kinase 22.7.11.220.466
5aacVGHALK tyrosine kinase receptor2.7.10.10.466
2pwlACPFibroblast growth factor receptor 2/0.465
3dfcANPDeath-associated protein kinase 12.7.11.10.465
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.465
4i5cC5ITyrosine-protein kinase JAK1/0.465
1e9hINRCyclin-dependent kinase 22.7.11.220.464
1ke6LS2Cyclin-dependent kinase 22.7.11.220.464
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.464
2bkzSBCCyclin-dependent kinase 22.7.11.220.464
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.464
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.464
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.464
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.464
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.464
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.463
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.463
4fod0UVALK tyrosine kinase receptor2.7.10.10.463
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.463
4ix6ADPUncharacterized protein/0.463
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.462
1pxmCK5Cyclin-dependent kinase 22.7.11.220.462
2cn8DBQSerine/threonine-protein kinase Chk22.7.11.10.462
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.462
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.462
4erkOLOMitogen-activated protein kinase 12.7.11.240.462
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.462
2acxANPG protein-coupled receptor kinase 62.7.11.160.461
2j9mPY8Cyclin-dependent kinase 22.7.11.220.461
2w1fL0FAurora kinase A2.7.11.10.461
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.461
3ral04ZCyclin-dependent kinase 22.7.11.220.461
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.461
4ez50RSCyclin-dependent kinase 62.7.11.220.461
4jbqVX6Aurora kinase A2.7.11.10.461
1eh4IC1Casein kinase I homolog 12.7.11.10.460
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
2c4g514Cyclin-dependent kinase 22.7.11.220.460
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.460
2izuP01Casein kinase I isoform gamma-32.7.11.10.460
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.460
3a8wATPProtein kinase C iota type2.7.11.130.460
3s4qNK0Mitogen-activated protein kinase 14/0.460
4a4l939Serine/threonine-protein kinase PLK12.7.11.210.460
4l445FIRibosomal protein S6 kinase beta-12.7.11.10.460
4qnaX11Serine/threonine-protein kinase 242.7.11.10.460
5aabVGHALK tyrosine kinase receptor2.7.10.10.460
1oguST8Cyclin-dependent kinase 22.7.11.220.459
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.459
2c5nCK8Cyclin-dependent kinase 22.7.11.220.459
2itpAEEEpidermal growth factor receptor2.7.10.10.459
2j7t274Serine/threonine-protein kinase 102.7.11.10.459
2xngA0HAurora kinase A2.7.11.10.459
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.459
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.459
4e6d0NUTyrosine-protein kinase JAK2/0.459
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.459
4gk3L87Ephrin type-A receptor 32.7.10.10.459
4jqeANPCasein kinase II subunit alpha2.7.11.10.459
4ysjADPCalmodulin-like domain protein kinase/0.459
1jklANPDeath-associated protein kinase 12.7.11.10.458
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.458
4brxKGWFocal adhesion kinase 12.7.10.20.458
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.458
4ivc1J6Tyrosine-protein kinase JAK1/0.458
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.458
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.458
4wsqKSAAP2-associated protein kinase 12.7.11.10.458
2itqITQEpidermal growth factor receptor2.7.10.10.457
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.457
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.457
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.457
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.457
3pe2E1BCasein kinase II subunit alpha2.7.11.10.457
3qxpX64Cyclin-dependent kinase 22.7.11.220.457
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4bbfO19Tyrosine-protein kinase JAK2/0.457
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.457
4fuxE75Mitogen-activated protein kinase 12.7.11.240.457
1oitHDTCyclin-dependent kinase 22.7.11.220.456
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
2cchATPCyclin-dependent kinase 22.7.11.220.456
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
3gu7ADPDeath-associated protein kinase 12.7.11.10.456
3rvg17PTyrosine-protein kinase JAK2/0.456
4b8lA0PAurora kinase B-A2.7.11.10.456
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.456
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4fyn0VETyrosine-protein kinase SYK2.7.10.20.456
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.456
5auzGENDeath-associated protein kinase 12.7.11.10.456
1m2rMNYCasein kinase II subunit alpha2.7.11.10.455
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.455
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.455
4gmy0X5Tyrosine-protein kinase JAK2/0.455
4j97ACPFibroblast growth factor receptor 2/0.455
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.455
4wkqIREEpidermal growth factor receptor2.7.10.10.455
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.454
2vgoAD5Aurora kinase B-A2.7.11.10.454
2wipP49Cyclin-dependent kinase 22.7.11.220.454
2xneASHAurora kinase A2.7.11.10.454
3c4wATPRhodopsin kinase/0.454
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.454
3k5uPFQAurora kinase A2.7.11.10.454
4j95ACPFibroblast growth factor receptor 2/0.454
5av3KMPDeath-associated protein kinase 12.7.11.10.454
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.453
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
2j0k4STFocal adhesion kinase 12.7.10.20.453
2pvnP63Casein kinase II subunit alpha2.7.11.10.453
2uzbC75Cyclin-dependent kinase 22.7.11.220.453
2xikJ60Serine/threonine-protein kinase 252.7.11.10.453
2xp2VGHALK tyrosine kinase receptor2.7.10.10.453
3c50ADPRhodopsin kinase/0.453
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.453
3lctADPALK tyrosine kinase receptor2.7.10.10.453
3nux3NVCyclin-dependent kinase 62.7.11.220.453
3r9dX6BCyclin-dependent kinase 22.7.11.220.453
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
1ke5LS1Cyclin-dependent kinase 22.7.11.220.452
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
1xl2189Gag-Pol polyprotein3.4.23.160.452
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
2uzeC95Cyclin-dependent kinase 22.7.11.220.452
2w06FRVCyclin-dependent kinase 22.7.11.220.452
2xa4AZ5Tyrosine-protein kinase JAK2/0.452
3nc9TR3Ketohexokinase/0.452
4hge15VTyrosine-protein kinase JAK2/0.452
5dr6SKEAurora kinase A2.7.11.10.452
1finATPCyclin-dependent kinase 22.7.11.220.451
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.451
1oecAA2Fibroblast growth factor receptor 2/0.451
2eufLQQCyclin-dependent kinase 62.7.11.220.451
2r64740Cyclin-dependent kinase 22.7.11.220.451
3a60STURibosomal protein S6 kinase beta-12.7.11.10.451
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
3c4zADPRhodopsin kinase/0.451
3lfqA28Cyclin-dependent kinase 22.7.11.220.451
4f081RSTyrosine-protein kinase JAK2/0.451
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.451
4i22IREEpidermal growth factor receptor2.7.10.10.451
4jhz1KVBeta-glucuronidase3.2.1.310.451
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.451
4y93746Tyrosine-protein kinase/0.451
2uzlC94Cyclin-dependent kinase 22.7.11.220.450
2w17I19Cyclin-dependent kinase 22.7.11.220.450
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.450
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.450
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.450
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.450
4bgg844Activin receptor type-12.7.11.300.450
4nks2M2Fibroblast growth factor receptor 1/0.450
2izt23DCasein kinase I isoform gamma-32.7.11.10.449
2jkqVG8Focal adhesion kinase 12.7.10.20.449
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.449
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.449
3emg685Tyrosine-protein kinase SYK2.7.10.20.449
4dt9GMPAPH(2'')-Id/0.449
4eooATPCyclin-dependent kinase 22.7.11.220.449
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.449
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.449
1unlRRCCyclin-dependent-like kinase 52.7.11.10.448
1v1k3FPCyclin-dependent kinase 22.7.11.220.448
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.448
2iw84SPCyclin-dependent kinase 22.7.11.220.448
2j0j4STFocal adhesion kinase 12.7.10.20.448
2z7qACPRibosomal protein S6 kinase alpha-12.7.11.10.448
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.448
3pxkPXKFocal adhesion kinase 12.7.10.20.448
3r8lZ30Cyclin-dependent kinase 22.7.11.220.448
3rni21ZCyclin-dependent kinase 22.7.11.220.448
3tnwF18Cyclin-dependent kinase 22.7.11.220.448
3vjoANPEpidermal growth factor receptor2.7.10.10.448
4anqVGHALK tyrosine kinase receptor2.7.10.10.448
4ehzJAKTyrosine-protein kinase JAK1/0.448
4ek816KCyclin-dependent kinase 22.7.11.220.448
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4fkv61KCyclin-dependent kinase 22.7.11.220.448
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.447
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.447
3bu5ATPInsulin receptor2.7.10.10.447
3ddpRC8Cyclin-dependent kinase 22.7.11.220.447
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.447
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.447
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.447
4ansVGHALK tyrosine kinase receptor2.7.10.10.447
4aqc88ATyrosine-protein kinase JAK2/0.447
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.447
4dtaADNAPH(2'')-Id/0.447
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.447
5dnrATPAurora kinase A2.7.11.10.447
5dpvSKEAurora kinase A2.7.11.10.447
5e8ySTUTGF-beta receptor type-22.7.11.300.447
2bfyH1NAurora kinase B-A2.7.11.10.446
2qo9ANPEphrin type-A receptor 32.7.10.10.446
2xru400Aurora kinase A2.7.11.10.446
3ztxZTXAurora kinase B-A2.7.11.10.446
1bxoPP7Penicillopepsin-13.4.23.200.445
1oirHDYCyclin-dependent kinase 22.7.11.220.445
1ppm0P1Penicillopepsin-13.4.23.200.445
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.445
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.445
3iok1P6Tyrosine-protein kinase JAK2/0.445
3raiX85Cyclin-dependent kinase 22.7.11.220.445
3rak03ZCyclin-dependent kinase 22.7.11.220.445
4e4m0NHTyrosine-protein kinase JAK2/0.445
4j99ACPFibroblast growth factor receptor 2/0.445
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.445
1oi9N20Cyclin-dependent kinase 22.7.11.220.444
1vjy460TGF-beta receptor type-12.7.11.300.444
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
3d7tSTUTyrosine-protein kinase CSK/0.444
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.444
3gu83GUDeath-associated protein kinase 12.7.11.10.444
3hx4ANPCalmodulin-domain protein kinase 1/0.444
3q92XNBKetohexokinase/0.444
3qa2XNAKetohexokinase/0.444
3rk507ZCyclin-dependent kinase 22.7.11.220.444
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.444
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.444
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.444
1w0xOLOCyclin-dependent kinase 22.7.11.220.443
2dwbANPAurora kinase A2.7.11.10.443
2pvlP55Casein kinase II subunit alpha2.7.11.10.443
2vnwM01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2yfxVGHALK tyrosine kinase receptor2.7.10.10.443
3my5RFZCyclin-dependent kinase 22.7.11.220.443
3umw596Serine/threonine-protein kinase pim-12.7.11.10.443
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.443
4ccbOFGALK tyrosine kinase receptor2.7.10.10.443
4dgnLU2Casein kinase II subunit alpha2.7.11.10.443
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.443
4qmpDKISerine/threonine-protein kinase 242.7.11.10.443
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.442
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.442
4c58824Cyclin-G-associated kinase2.7.11.10.442
4eor4SPCyclin-dependent kinase 22.7.11.220.442
4f650S9Fibroblast growth factor receptor 1/0.442
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4jq8KJ8Epidermal growth factor receptor2.7.10.10.442
4qgiROCGag-Pol polyprotein3.4.23.160.442
2itnANPEpidermal growth factor receptor2.7.10.10.441
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.10.441
3ml9ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4fmqANPMitogen-activated protein kinase 12.7.11.240.441
4fnzNZFALK tyrosine kinase receptor2.7.10.10.441
4ivd15TTyrosine-protein kinase JAK1/0.441
5aut2ANDeath-associated protein kinase 12.7.11.10.441
2vrx447Aurora kinase B-A2.7.11.10.440
3le62BZCyclin-dependent kinase 22.7.11.220.440
3rk708ZCyclin-dependent kinase 22.7.11.220.440
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.440
3zmmF9JTyrosine-protein kinase JAK2/0.440
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.440
4gk4L90Ephrin type-A receptor 32.7.10.10.440
4gu610NFocal adhesion kinase 12.7.10.20.440
4hgs15GCasein kinase I isoform gamma-32.7.11.10.440
4hnf16WCasein kinase I isoform delta2.7.11.10.440
4qmySTUSerine/threonine-protein kinase 242.7.11.10.440