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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2zx8ZX8Alpha-L-fucosidase, putative

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2zx8ZX8Alpha-L-fucosidase, putative/1.000
2zx7ZX7Alpha-L-fucosidase, putative/0.899
2zx9ZX9Alpha-L-fucosidase, putative/0.618
2zx6ZX6Alpha-L-fucosidase, putative/0.610
2zx5ZX5Alpha-L-fucosidase, putative/0.607
2zxbZXBAlpha-L-fucosidase, putative/0.543
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449