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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2zcjSAHModification methylase HhaI2.1.1.37

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2zcjSAHModification methylase HhaI2.1.1.371.000
2z6uSAHModification methylase HhaI2.1.1.370.757
7mhtSAHModification methylase HhaI2.1.1.370.669
3mhtSAHModification methylase HhaI2.1.1.370.656
1skmSAHModification methylase HhaI2.1.1.370.618
9mhtSAHModification methylase HhaI2.1.1.370.606
5mhtSAHModification methylase HhaI2.1.1.370.594
8mhtSAHModification methylase HhaI2.1.1.370.582
2i9kSAHModification methylase HhaI2.1.1.370.577
2c7qSAHModification methylase HhaI2.1.1.370.573
2uyhSAHModification methylase HhaI2.1.1.370.568
1fjxSAHModification methylase HhaI2.1.1.370.567
1mhtSAHModification methylase HhaI2.1.1.370.557
10mhSAHModification methylase HhaI2.1.1.370.531
4mhtSAHModification methylase HhaI2.1.1.370.507
2hmySAMModification methylase HhaI2.1.1.370.501
3qv2SAH5-cytosine DNA methyltransferase/0.458