sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2zce | PYL | Pyrrolysine--tRNA ligase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2zce | PYL | Pyrrolysine--tRNA ligase | / | 1.000 | |
| 2q7g | CCL | Pyrrolysine--tRNA ligase | / | 0.585 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.535 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.530 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.524 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.510 | |
| 3dpd | 41A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.506 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.505 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.502 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.500 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.498 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.497 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.497 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.495 | |
| 2ejz | SAH | Diphthine synthase | / | 0.494 | |
| 3pre | 3RE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.494 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.494 | |
| 4czt | CPS | CBL-interacting serine/threonine-protein kinase 23 | 2.7.11.1 | 0.491 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.491 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.489 | |
| 1m8h | 6NI | Nitric oxide synthase, inducible | 1.14.13.39 | 0.488 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.488 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.487 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.487 | |
| 4j6i | 1JV | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.486 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.486 | |
| 1e8w | QUE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.485 | |
| 3ml9 | ML9 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.485 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.485 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.484 | |
| 3e7i | B2 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.484 | |
| 3e6o | A55 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.483 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.482 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.482 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.482 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.481 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.481 | |
| 3a8w | ATP | Protein kinase C iota type | 2.7.11.13 | 0.481 | |
| 4bqu | CLR | Japanin | / | 0.481 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.480 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.479 | |
| 2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.478 | |
| 4bwa | N0B | Pyrrolysine--tRNA ligase | / | 0.478 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.478 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.476 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.476 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.475 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.475 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.475 | |
| 4l23 | X6K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.475 | |
| 1be4 | PCG | Nucleoside diphosphate kinase A 2 | 2.7.4.6 | 0.474 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.474 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.474 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.474 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.473 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.473 | |
| 1m9r | INE | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.471 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.470 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.470 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.470 | |
| 2pmn | K51 | Protein kinase 7 | / | 0.469 | |
| 2zio | AYB | Pyrrolysine--tRNA ligase | / | 0.469 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.468 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.468 | |
| 3ngu | ADP | Nucleoside diphosphate kinase | / | 0.468 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.468 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.468 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.467 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.466 | |
| 2xsz | ATP | RuvB-like 2 | 3.6.4.12 | 0.465 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.464 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.464 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.464 | |
| 4qjc | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 2a5u | QYT | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.461 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.461 | |
| 3e7t | B14 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.461 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.461 | |
| 4kto | FAD | Putative isovaleryl-CoA dehydrogenase protein | / | 0.461 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.460 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.460 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.460 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.460 | |
| 3vqx | BLK | Pyrrolysine--tRNA ligase | / | 0.460 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.459 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.459 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.458 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 4gqe | 6KJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.458 | |
| 4rrf | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.458 | |
| 1sm2 | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.457 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.457 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 5h84 | 1VU | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.457 | |
| 1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.456 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.455 | |
| 1z4r | ACO | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.455 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.455 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.455 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.455 | |
| 4bcq | TJF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 4lwb | QJ8 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.455 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.454 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.454 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.454 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.454 | |
| 4qoe | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.454 | |
| 5aab | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.454 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.453 | |
| 1tj2 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.453 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.453 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.453 | |
| 3up0 | D7S | aceDAF-12 | / | 0.453 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.453 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1g0r | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.452 | |
| 1m9m | 6NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.452 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.452 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.452 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.451 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 3ebf | 332 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.451 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.451 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.451 | |
| 4ful | 0VU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4h38 | 0YX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.451 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.450 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.450 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.450 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 3eai | 328 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.450 | |
| 3x2e | NAI | Adenosylhomocysteinase | / | 0.450 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.450 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.450 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.449 | |
| 2a0c | CK9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2aax | PDN | Mineralocorticoid receptor | / | 0.449 | |
| 2c31 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.449 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.449 | |
| 3bgr | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.449 | |
| 4jsj | QJ7 | Nitric oxide synthase, brain | 1.14.13.39 | 0.449 | |
| 4ug7 | 1EV | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.449 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.448 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2fzm | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.448 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.448 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.448 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.448 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.448 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.448 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.447 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2pnu | ENM | Androgen receptor | / | 0.447 | |
| 2v7a | 627 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.447 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.447 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.446 | |
| 1wc3 | APC | Adenylate cyclase | / | 0.446 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3qts | X46 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.446 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.446 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.446 | |
| 1m9j | CLW | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.445 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.445 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.445 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.445 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.445 | |
| 2p15 | EZT | Estrogen receptor | / | 0.444 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.444 | |
| 3nef | PYV | Abscisic acid receptor PYL1 | / | 0.444 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.444 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.444 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.444 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 4fvz | 4KJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 4tv3 | ML9 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.444 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.444 | |
| 1fin | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.443 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.443 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.443 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.443 | |
| 4fa6 | 0TA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4jse | QJ2 | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 4phl | PIL | Phosphodiesterase | / | 0.443 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.442 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2bxq | IMN | Serum albumin | / | 0.442 | |
| 2olc | ADP | Methylthioribose kinase | 2.7.1.100 | 0.442 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2y37 | A54 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.442 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.442 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3my5 | RFZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.442 | |
| 4bcm | T7Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4dk5 | 0KO | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.442 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.442 | |
| 5h86 | BCO | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.442 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.442 | |
| 1p93 | DEX | Glucocorticoid receptor | / | 0.441 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.441 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.441 | |
| 2pkl | DHT | Androgen receptor | / | 0.441 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.441 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 3jx0 | JI4 | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3qtr | X36 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3roy | 22Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4b8l | A0P | Aurora kinase B-A | 2.7.11.1 | 0.441 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.441 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.441 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 4ks7 | X4Z | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.441 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 1tvw | CB3 | Thymidylate synthase | / | 0.440 | |
| 2amb | 17H | Androgen receptor | / | 0.440 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2bgj | FAD | NADPH:ferredoxin reductase | / | 0.440 | |
| 2gnf | Y27 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 3cse | N22 | Uncharacterized protein | / | 0.440 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.440 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.440 | |
| 3kdi | A8S | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3nmh | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.440 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.440 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4lwa | Q13 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.440 |