sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 1.000 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.528 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.475 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.470 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.467 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.463 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.463 | |
| 2w98 | P1Z | Prostaglandin reductase 2 | 1.3.1.48 | 0.455 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 5dc5 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.455 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.452 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.450 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.450 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.449 | |
| 1ysx | 4EB | Serum albumin | / | 0.448 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.447 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.447 | |
| 3up3 | XCA | aceDAF-12 | / | 0.446 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.446 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.445 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.445 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.445 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.444 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.444 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.444 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.444 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.443 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.443 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.442 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.442 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.442 | |
| 1fml | RTL | Retinol dehydratase | / | 0.441 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.441 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.441 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.441 | |
| 1ddu | CB3 | Thymidylate synthase | / | 0.440 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.440 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.440 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.440 |