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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2yxlSFG450aa long hypothetical fmu protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2yxlSFG450aa long hypothetical fmu protein/1.000
4fzvSAM5-methylcytosine rRNA methyltransferase NSUN42.1.10.594
4fp9SAM5-methylcytosine rRNA methyltransferase NSUN42.1.10.540
3m6wSAMRibosomal RNA small subunit methyltransferase F/0.496
3m6vSAMRibosomal RNA small subunit methyltransferase F/0.483
3a4tSFGtRNA (cytosine(48)-C(5))-methyltransferase2.1.10.464
1sqfSAMRibosomal RNA small subunit methyltransferase B2.1.1.1760.440