sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 1.000 | |
| 2ydd | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.741 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.712 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.655 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.641 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.599 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.571 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.559 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.552 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.546 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.534 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.516 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.510 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.505 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.504 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.491 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.488 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.488 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.488 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.488 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.486 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.485 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.482 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.481 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.480 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.480 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.479 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.476 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.475 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.474 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.473 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.472 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.471 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.471 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.471 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.469 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.469 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.469 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.468 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.468 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.467 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.466 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.466 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.465 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.463 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.462 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.461 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.461 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.461 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 4phl | PIL | Phosphodiesterase | / | 0.461 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.460 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.460 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.459 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.459 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.459 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.459 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.459 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.459 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.458 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.458 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.458 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.458 | |
| 4kqr | VPP | Peptidoglycan D,D-transpeptidase FtsI | / | 0.458 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.458 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.458 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.457 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.457 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.457 | |
| 4ovi | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.457 | |
| 4ytn | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.457 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.456 | |
| 2o12 | FMN | Chorismate synthase | / | 0.456 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.456 | |
| 4hxy | NDP | Plm1 | / | 0.456 | |
| 5dp2 | NAP | CurF | / | 0.456 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.455 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.455 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.454 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.454 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.454 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.453 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.453 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 3hu1 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.453 | |
| 3tqc | ADP | Pantothenate kinase | / | 0.453 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 5eso | ISC | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.453 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.453 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.452 | |
| 2zi6 | 3D1 | Deoxycytidine kinase | 2.7.1.74 | 0.452 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4die | C5P | Cytidylate kinase | / | 0.452 | |
| 4gu5 | FAD | Cryptochrome-1 | / | 0.452 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.452 | |
| 4u7w | NDP | MxaA | / | 0.452 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.452 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.452 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.451 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3eku | CY9 | Actin-5C | / | 0.451 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.451 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.451 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.451 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.450 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.449 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.449 | |
| 3eek | 53S | Uncharacterized protein | / | 0.449 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.449 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.449 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 5dcy | NAP | Iridoid synthase | 1.3.1.99 | 0.449 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.448 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.448 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.448 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.448 | |
| 4ki0 | ANP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.448 | |
| 4njo | NAD | D-3-phosphoglycerate dehydrogenase, putative | / | 0.448 | |
| 5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.448 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.447 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.447 | |
| 3n5w | XFJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.447 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.447 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.447 | |
| 4jic | FMN | GTN Reductase | / | 0.447 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.446 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.446 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.446 | |
| 2q3e | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.446 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.446 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.446 | |
| 4tv9 | GTP | Tubulin alpha-1B chain | / | 0.446 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.446 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.445 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.445 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.445 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.445 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.445 | |
| 4d9e | LCS | D-cysteine desulfhydrase | / | 0.445 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.445 | |
| 4l9k | EHF | Serum albumin | / | 0.445 | |
| 4tlb | AGS | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.445 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.445 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.445 | |
| 1c7o | PPG | Hemolysin | / | 0.444 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.444 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.444 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.444 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.444 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.444 | |
| 3kej | 3EJ | Collagenase 3 | 3.4.24 | 0.444 | |
| 3v2u | ATP | Protein GAL3 | / | 0.444 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.444 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.444 | |
| 4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.444 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.444 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.443 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1e2n | RCA | Thymidine kinase | / | 0.443 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.443 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.443 | |
| 1w48 | APC | NTPase P4 | / | 0.443 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.443 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.443 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.443 | |
| 4kqq | VPP | Peptidoglycan D,D-transpeptidase FtsI | / | 0.443 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.443 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.443 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.442 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.442 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.442 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 4o4i | GTP | Tubulin alpha-1B chain | / | 0.442 | |
| 4tl8 | AGS | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.442 | |
| 5hwp | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
| 1nue | GDP | Nucleoside diphosphate kinase B | 2.7.4.6 | 0.441 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.441 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.441 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.441 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.441 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.441 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.441 | |
| 4rx6 | ATP | Nitrogen regulatory PII-like protein | / | 0.441 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.440 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.440 | |
| 2dxf | GNP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.440 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.440 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.440 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.440 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.440 | |
| 3gnv | XNZ | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.440 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.440 | |
| 3pn1 | IVH | DNA ligase | / | 0.440 | |
| 4gvj | ADP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.440 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.440 |