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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2yczI32Beta-1 adrenergic receptor

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2yczI32Beta-1 adrenergic receptor/1.000
2ycyP32Beta-1 adrenergic receptor/0.641
2ycxP32Beta-1 adrenergic receptor/0.592
5d5aCAUBeta-2 adrenergic receptor/0.587
5d6lCAUBeta-2 adrenergic receptor/0.585
4amjCVDBeta-1 adrenergic receptor/0.574
5d5bCAUBeta-2 adrenergic receptor/0.567
4gbrCAUBeta-2 adrenergic receptor/0.567
2rh1CAUBeta-2 adrenergic receptor/0.566
4amiG90Beta-1 adrenergic receptor/0.555
2ycwCAUBeta-1 adrenergic receptor/0.548
5f8uP32Beta-1 adrenergic receptor/0.542
5a8eXTKBeta-1 adrenergic receptor/0.540
4bvnP32Beta-1 adrenergic receptor/0.536
3ny9JSZBeta-2 adrenergic receptor/0.535
3d4sTIMBeta-2 adrenergic receptor/0.526
2y0468HBeta-1 adrenergic receptor/0.515
3ny8JRZBeta-2 adrenergic receptor/0.515
5jqhCAUBeta-2 adrenergic receptor/0.514
2vt4P32Beta-1 adrenergic receptor/0.510
3nyaJTZBeta-2 adrenergic receptor/0.508
2y01Y00Beta-1 adrenergic receptor/0.504
2y035FWBeta-1 adrenergic receptor/0.489
2y02WHJBeta-1 adrenergic receptor/0.485
4ldeP0GBeta-2 adrenergic receptor/0.468
3zpqXF5Beta-1 adrenergic receptor/0.464
4iarERM5-hydroxytryptamine receptor 1B/0.453