sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2yay | DUP | DUTPase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2yay | DUP | DUTPase | / | 1.000 | |
| 4dkb | DUN | Deoxyuridine triphosphatase, putative | / | 0.626 | |
| 2cje | DUN | DUTPase | / | 0.599 | |
| 4dlc | UMP | Deoxyuridine triphosphatase, putative | / | 0.590 | |
| 2cic | DUP | DUTPase | / | 0.527 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.481 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.471 | |
| 4dyn | 0MR | Nucleoprotein | / | 0.453 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.451 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.451 | |
| 3tfn | 2CJ | Dehydrosqualene synthase | / | 0.450 | |
| 4to5 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.450 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.447 | |
| 4rph | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.447 | |
| 2zcq | B65 | Dehydrosqualene synthase | / | 0.446 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.445 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.444 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.444 | |
| 4g1c | CNA | NAD-dependent protein deacylase sirtuin-5, mitochondrial | / | 0.444 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.443 | |
| 5ckw | ANP | Uncharacterized protein | / | 0.443 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.442 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.441 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.441 | |
| 5doz | NDP | JamJ | / | 0.440 |